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The map label for this gene is ppiD [H]

Identifier: 99080985

GI number: 99080985

Start: 1230946

End: 1232781

Strand: Reverse

Name: ppiD [H]

Synonym: TM1040_1144

Alternate gene names: 99080985

Gene position: 1232781-1230946 (Counterclockwise)

Preceding gene: 99080986

Following gene: 99080984

Centisome position: 38.51

GC content: 62.53

Gene sequence:

>1836_bases
ATGAAAAAGCTTTCAAAGACCTTCGTTTGGATCCTCATGGGTCTGTTGTTCGTGGGGCTTGCGGGCTTTGGTGCGATCAA
CGTATCCGGCACCACCCGCACGCTGGCCACCGTGGGTGATGCCACCGTCAGCGTTGATGACTACGCCCGCGCCCTGCAAC
AGGAACAACGTGCCATTCAGGCCCAGTCCGGCCAGTCCATTCCCCTGTCGCAGCTGATCGCCATGGGCGTGGATCGCGGT
GTGCTCTCGGGGCTTGTGGCTACGGCCGCGCTCGACAATGAGCTCACAGAGATCGGCCTGTCTGTGGGCGACGAAGTGCT
GCTCGAAGAGATCACCCGGATTTCGGCCTTCCAGGGGTCTGATGGCAGCTTCAGCCGCGACAACTACCGTTTTGCCCTTG
ATAACGCAGGTCTGTCCGAGGCTGAGTTCGAGGCCGACATGCGGTCTGAAACCGCGCGCACGCTGCTGCAAGGGGCCATC
ACCGGTGGCACCCGCATGCCCGCGGTGCTGGGCGAGACACTCACCAACTATATCGGTGCGCGTCGCAGCTTTTCCTATGT
TCGGCTCGCCGAGGCCAACGTCCCCCTGACCGCGATCGCGCCCACCGAGGATGCGCTCAAGGCTTATTACGAGACCCACA
TCGAGGATTTCACCCTGCCCGAGACCAAGGTGATCACCTATGTCGCCCTGCGCCCCGACGCGCTGGTGGATCAGGTCGAG
GTGGATGAAACCGCTCTGCGCGGTCTCTACGAGGAGCGCGACGCAGAATTCAACGTCCCCGAGCGCCGCCTTGTCGAACA
GCTGGTGTTCCCCGACGAGGACGCCGCCCAAACCGCCAAGGCCGAGCTCGATGTGGGGGGGACCACCTTTGAAACCCTGG
TGGCAGATCGCGAACTCTCCCTGTCGGACATCGACATGGGTGATGTGGCGATTGGCGACCTTGGCGCTGCGGGCGAAGCC
GTCTTTGCCGCCGACGTGGGCGCCGTGGTTGGCCCGCTTCCATCAGATTTTGGCCCCGCGCTCTACCGTGTGAACGGCGT
GCTCGAAGCGAATTTCACCAGCTTTGAAGAGGCCCTGCCGGTCTTGCGCGAAGAGCTGGCTCTGGATCGTGCCCGCCGCC
TGATTGAATCCCGCGCCGAAGGGCTGGATGATGCGCTCGCCGGTGGCGCGACGCTCGAAGATCTCGCCGAGGAAGAAAAC
GGCGTGGTGCTCGGCCAGCTTGACTGGACCGCCAATACCACTGACGACATTGCGGCCTATGACACCTTCCGCAACGCGGC
AGAGGCCGTGACGACCGAAGATTTCCCCGAAGTGGGCTATCTCGAGGATGGCAGCCTCTTTGCGTTGCGCCTCGATGAGG
TCCTGCCCCCGCGCCCCGAGCCCTTTGAGGACGCGCGCACAGCCGTTTCCGAAGCCTACGAGGGCGACCGGATCGCCAAG
GCGCTTGCCGCGCAGGCCGAACAGATCAAAACCGCGACCGAGGGCAACAACGGCCAGTTCCCCGAAGGTCGCGAAGTGAT
CGAGCAGACCGGCCTTACCCGGACCGCCTATCTCGATCAGACCCCGGTTGATCTCCTCAATCAGGTGTTCGAAATGGAAG
TGGGCGAAGTGCGTGTTGTCTCCGACGCAGAAGGCACTGTTGTGGTGCGTCTCGACGAGATCCTGCCCCCGGATGACGGC
AATGACATGCAGTTCCTGTCTCAGGCGCTCGGCGATCAGCTGAACCAGTCGCTCTCCAACGAGATCTTCCAGATCTATCT
GCAATCGGTTCAGACCCGCGCCCGTCCGCAGGTCAACCAACAGGCCGTGAATGCTGTTCACGCCAACTTCCAGTAA

Upstream 100 bases:

>100_bases
GCGACGACAGGAGACCGCCGAGCCATTCGGCAGAATTTCGGCCGCCCGGCATCCCCGCCCCGGCGCGCCAGCAAAAAAGA
CGACATAAAGGGCCGCAGGC

Downstream 100 bases:

>100_bases
CTCAGTACGAGGCGCATGCGCTTATGGCCCTGATCCCCGATTTCGACAGTTTCGCCAAAGCCTATGAGGCGGGCGAAAAC
CAGGTGGTCTACACACGGCT

Product: putative peptidyl-prolyl cis-trans isomerse D

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 611; Mature: 611

Protein sequence:

>611_residues
MKKLSKTFVWILMGLLFVGLAGFGAINVSGTTRTLATVGDATVSVDDYARALQQEQRAIQAQSGQSIPLSQLIAMGVDRG
VLSGLVATAALDNELTEIGLSVGDEVLLEEITRISAFQGSDGSFSRDNYRFALDNAGLSEAEFEADMRSETARTLLQGAI
TGGTRMPAVLGETLTNYIGARRSFSYVRLAEANVPLTAIAPTEDALKAYYETHIEDFTLPETKVITYVALRPDALVDQVE
VDETALRGLYEERDAEFNVPERRLVEQLVFPDEDAAQTAKAELDVGGTTFETLVADRELSLSDIDMGDVAIGDLGAAGEA
VFAADVGAVVGPLPSDFGPALYRVNGVLEANFTSFEEALPVLREELALDRARRLIESRAEGLDDALAGGATLEDLAEEEN
GVVLGQLDWTANTTDDIAAYDTFRNAAEAVTTEDFPEVGYLEDGSLFALRLDEVLPPRPEPFEDARTAVSEAYEGDRIAK
ALAAQAEQIKTATEGNNGQFPEGREVIEQTGLTRTAYLDQTPVDLLNQVFEMEVGEVRVVSDAEGTVVVRLDEILPPDDG
NDMQFLSQALGDQLNQSLSNEIFQIYLQSVQTRARPQVNQQAVNAVHANFQ

Sequences:

>Translated_611_residues
MKKLSKTFVWILMGLLFVGLAGFGAINVSGTTRTLATVGDATVSVDDYARALQQEQRAIQAQSGQSIPLSQLIAMGVDRG
VLSGLVATAALDNELTEIGLSVGDEVLLEEITRISAFQGSDGSFSRDNYRFALDNAGLSEAEFEADMRSETARTLLQGAI
TGGTRMPAVLGETLTNYIGARRSFSYVRLAEANVPLTAIAPTEDALKAYYETHIEDFTLPETKVITYVALRPDALVDQVE
VDETALRGLYEERDAEFNVPERRLVEQLVFPDEDAAQTAKAELDVGGTTFETLVADRELSLSDIDMGDVAIGDLGAAGEA
VFAADVGAVVGPLPSDFGPALYRVNGVLEANFTSFEEALPVLREELALDRARRLIESRAEGLDDALAGGATLEDLAEEEN
GVVLGQLDWTANTTDDIAAYDTFRNAAEAVTTEDFPEVGYLEDGSLFALRLDEVLPPRPEPFEDARTAVSEAYEGDRIAK
ALAAQAEQIKTATEGNNGQFPEGREVIEQTGLTRTAYLDQTPVDLLNQVFEMEVGEVRVVSDAEGTVVVRLDEILPPDDG
NDMQFLSQALGDQLNQSLSNEIFQIYLQSVQTRARPQVNQQAVNAVHANFQ
>Mature_611_residues
MKKLSKTFVWILMGLLFVGLAGFGAINVSGTTRTLATVGDATVSVDDYARALQQEQRAIQAQSGQSIPLSQLIAMGVDRG
VLSGLVATAALDNELTEIGLSVGDEVLLEEITRISAFQGSDGSFSRDNYRFALDNAGLSEAEFEADMRSETARTLLQGAI
TGGTRMPAVLGETLTNYIGARRSFSYVRLAEANVPLTAIAPTEDALKAYYETHIEDFTLPETKVITYVALRPDALVDQVE
VDETALRGLYEERDAEFNVPERRLVEQLVFPDEDAAQTAKAELDVGGTTFETLVADRELSLSDIDMGDVAIGDLGAAGEA
VFAADVGAVVGPLPSDFGPALYRVNGVLEANFTSFEEALPVLREELALDRARRLIESRAEGLDDALAGGATLEDLAEEEN
GVVLGQLDWTANTTDDIAAYDTFRNAAEAVTTEDFPEVGYLEDGSLFALRLDEVLPPRPEPFEDARTAVSEAYEGDRIAK
ALAAQAEQIKTATEGNNGQFPEGREVIEQTGLTRTAYLDQTPVDLLNQVFEMEVGEVRVVSDAEGTVVVRLDEILPPDDG
NDMQFLSQALGDQLNQSLSNEIFQIYLQSVQTRARPQVNQQAVNAVHANFQ

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=522, Percent_Identity=23.3716475095785, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 66052; Mature: 66052

Theoretical pI: Translated: 3.90; Mature: 3.90

Prosite motif: PS00398 RECOMBINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLSKTFVWILMGLLFVGLAGFGAINVSGTTRTLATVGDATVSVDDYARALQQEQRAIQ
CCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEHEECCCCEEEHHHHHHHHHHHHHHHH
AQSGQSIPLSQLIAMGVDRGVLSGLVATAALDNELTEIGLSVGDEVLLEEITRISAFQGS
HCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
DGSFSRDNYRFALDNAGLSEAEFEADMRSETARTLLQGAITGGTRMPAVLGETLTNYIGA
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
RRSFSYVRLAEANVPLTAIAPTEDALKAYYETHIEDFTLPETKVITYVALRPDALVDQVE
CCCCCEEEEECCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCEEEEEEECCHHHHHHHH
VDETALRGLYEERDAEFNVPERRLVEQLVFPDEDAAQTAKAELDVGGTTFETLVADRELS
HHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHCCCCC
LSDIDMGDVAIGDLGAAGEAVFAADVGAVVGPLPSDFGPALYRVNGVLEANFTSFEEALP
CCCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHCCCEEECCCHHHHHHHH
VLREELALDRARRLIESRAEGLDDALAGGATLEDLAEEENGVVLGQLDWTANTTDDIAAY
HHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHCCCCEEEEEECCCCCCCCHHHHH
DTFRNAAEAVTTEDFPEVGYLEDGSLFALRLDEVLPPRPEPFEDARTAVSEAYEGDRIAK
HHHHHHHHHHCCCCCCCCCEECCCCEEEEEEHHHCCCCCCCHHHHHHHHHHHHCHHHHHH
ALAAQAEQIKTATEGNNGQFPEGREVIEQTGLTRTAYLDQTPVDLLNQVFEMEVGEVRVV
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCCEEEE
SDAEGTVVVRLDEILPPDDGNDMQFLSQALGDQLNQSLSNEIFQIYLQSVQTRARPQVNQ
ECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
QAVNAVHANFQ
HHHHHHHCCCC
>Mature Secondary Structure
MKKLSKTFVWILMGLLFVGLAGFGAINVSGTTRTLATVGDATVSVDDYARALQQEQRAIQ
CCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEHEECCCCEEEHHHHHHHHHHHHHHHH
AQSGQSIPLSQLIAMGVDRGVLSGLVATAALDNELTEIGLSVGDEVLLEEITRISAFQGS
HCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
DGSFSRDNYRFALDNAGLSEAEFEADMRSETARTLLQGAITGGTRMPAVLGETLTNYIGA
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
RRSFSYVRLAEANVPLTAIAPTEDALKAYYETHIEDFTLPETKVITYVALRPDALVDQVE
CCCCCEEEEECCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCEEEEEEECCHHHHHHHH
VDETALRGLYEERDAEFNVPERRLVEQLVFPDEDAAQTAKAELDVGGTTFETLVADRELS
HHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHCCCCC
LSDIDMGDVAIGDLGAAGEAVFAADVGAVVGPLPSDFGPALYRVNGVLEANFTSFEEALP
CCCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHCCCEEECCCHHHHHHHH
VLREELALDRARRLIESRAEGLDDALAGGATLEDLAEEENGVVLGQLDWTANTTDDIAAY
HHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHCCCCEEEEEECCCCCCCCHHHHH
DTFRNAAEAVTTEDFPEVGYLEDGSLFALRLDEVLPPRPEPFEDARTAVSEAYEGDRIAK
HHHHHHHHHHCCCCCCCCCEECCCCEEEEEEHHHCCCCCCCHHHHHHHHHHHHCHHHHHH
ALAAQAEQIKTATEGNNGQFPEGREVIEQTGLTRTAYLDQTPVDLLNQVFEMEVGEVRVV
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCCEEEE
SDAEGTVVVRLDEILPPDDGNDMQFLSQALGDQLNQSLSNEIFQIYLQSVQTRARPQVNQ
ECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
QAVNAVHANFQ
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]