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The map label for this gene is gapB [H]

Identifier: 99080952

GI number: 99080952

Start: 1192007

End: 1193008

Strand: Reverse

Name: gapB [H]

Synonym: TM1040_1111

Alternate gene names: 99080952

Gene position: 1193008-1192007 (Counterclockwise)

Preceding gene: 99080954

Following gene: 99080951

Centisome position: 37.27

GC content: 62.67

Gene sequence:

>1002_bases
ATGACCATCAAAGTTGGAATCAATGGCTTCGGACGTATCGGCCGCTGCACCCTCGCCCATATCGCGGGCAGCTTTCGCAA
CGATATCGAGGTGATCAAGGTCAATGCGACCGGCCCGATCGAGACGGCAGCGCATCTCATCAAATACGACAGCGTGCATG
GCCGTTTCCCCGGTCAGGTCGATTTCAGCGAAGGCCGCCTGAACCTTGGCCGCGGCGACATGCAGGTGTTTTCCACCTAC
GACATGGACACGCTGGACTGGGAAGGCTGCGATGTCGTGCTGGAATGCACCGGCAAATTCAACGATGGCCTGAAGGCGAA
GAAGCACCTCGAGCGCGGCGCAGGCAAGGTTCTGCTGTCCGCACCTGGCAAGAACGTGGACCGCACCGTGGTTTACGGCG
TCAACGACGAGGATCTTCTGTCCACCGACAAGATGGTCTCCAACGGGTCTTGCACCACCAACTGCCTTGCACCGCTGGCC
AAGGTACTGGACGAGGCCTTTGGCATCGAGCATGGCATCATGACCACCATCCACGCCTACACCGGCGATCAGCCGACGCT
AGACCGCCGTCACGACGATCTCTACCGCGCCCGTGCGGCAGCGATGTCGATGATCCCGACCTCTACGGGCGCGGCCAAGG
CGCTGGGTGAGGTTCTGCCGAACCTCAAGGGCCGTCTCGATGGCTCAGCGATCCGCGTGCCGACCCCGAATGTGTCCGCG
GTGGACCTGACCTTCCGCGCGGGGCGCGAGGTCACCGCCGAAGAGGTGAACGCCGCCGTGGCAGAGGCGTCCAAGGGCCA
TATGTCGCGCGTTCTGGGCTATGAGCCCGCGCCGCTGGTCTCGACCGACTTCAACCACACCGAAGAAAGCTCCATCTTTG
CGCCCGACCAGACCCGCGTGGTCGACGGTCGCATGGTGCGCGTGCTGGCGTGGTATGACAACGAATGGGGCTTCTCGGTC
CGGATGGCCGATGTTGCCACCGCCATGGGTCGCCTGAACTAA

Upstream 100 bases:

>100_bases
TGCGCTAACAGTCTGTGTTTACTCTAATTTCTTCTTTTTCCCGAGGTTAATGATCGCTATAGGCTGCCCCTAAGACAGCC
TTCTCGTGGAGACGACAGAG

Downstream 100 bases:

>100_bases
CACCTTCCTCGCGTGAGGGTTGAGATTTTACGCCCGGTCAGGCATAGCTGGCCGGGCGTATTTTATTGGGCTTCCCGCAT
GACCAACACCATCGCCATCG

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MTIKVGINGFGRIGRCTLAHIAGSFRNDIEVIKVNATGPIETAAHLIKYDSVHGRFPGQVDFSEGRLNLGRGDMQVFSTY
DMDTLDWEGCDVVLECTGKFNDGLKAKKHLERGAGKVLLSAPGKNVDRTVVYGVNDEDLLSTDKMVSNGSCTTNCLAPLA
KVLDEAFGIEHGIMTTIHAYTGDQPTLDRRHDDLYRARAAAMSMIPTSTGAAKALGEVLPNLKGRLDGSAIRVPTPNVSA
VDLTFRAGREVTAEEVNAAVAEASKGHMSRVLGYEPAPLVSTDFNHTEESSIFAPDQTRVVDGRMVRVLAWYDNEWGFSV
RMADVATAMGRLN

Sequences:

>Translated_333_residues
MTIKVGINGFGRIGRCTLAHIAGSFRNDIEVIKVNATGPIETAAHLIKYDSVHGRFPGQVDFSEGRLNLGRGDMQVFSTY
DMDTLDWEGCDVVLECTGKFNDGLKAKKHLERGAGKVLLSAPGKNVDRTVVYGVNDEDLLSTDKMVSNGSCTTNCLAPLA
KVLDEAFGIEHGIMTTIHAYTGDQPTLDRRHDDLYRARAAAMSMIPTSTGAAKALGEVLPNLKGRLDGSAIRVPTPNVSA
VDLTFRAGREVTAEEVNAAVAEASKGHMSRVLGYEPAPLVSTDFNHTEESSIFAPDQTRVVDGRMVRVLAWYDNEWGFSV
RMADVATAMGRLN
>Mature_332_residues
TIKVGINGFGRIGRCTLAHIAGSFRNDIEVIKVNATGPIETAAHLIKYDSVHGRFPGQVDFSEGRLNLGRGDMQVFSTYD
MDTLDWEGCDVVLECTGKFNDGLKAKKHLERGAGKVLLSAPGKNVDRTVVYGVNDEDLLSTDKMVSNGSCTTNCLAPLAK
VLDEAFGIEHGIMTTIHAYTGDQPTLDRRHDDLYRARAAAMSMIPTSTGAAKALGEVLPNLKGRLDGSAIRVPTPNVSAV
DLTFRAGREVTAEEVNAAVAEASKGHMSRVLGYEPAPLVSTDFNHTEESSIFAPDQTRVVDGRMVRVLAWYDNEWGFSVR
MADVATAMGRLN

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=330, Percent_Identity=41.5151515151515, Blast_Score=248, Evalue=4e-66,
Organism=Homo sapiens, GI7657116, Length=334, Percent_Identity=41.6167664670659, Blast_Score=242, Evalue=3e-64,
Organism=Escherichia coli, GI1789295, Length=334, Percent_Identity=43.1137724550898, Blast_Score=277, Evalue=7e-76,
Organism=Escherichia coli, GI1788079, Length=328, Percent_Identity=46.3414634146341, Blast_Score=276, Evalue=9e-76,
Organism=Caenorhabditis elegans, GI17534677, Length=332, Percent_Identity=43.6746987951807, Blast_Score=247, Evalue=6e-66,
Organism=Caenorhabditis elegans, GI17534679, Length=332, Percent_Identity=43.3734939759036, Blast_Score=246, Evalue=9e-66,
Organism=Caenorhabditis elegans, GI32566163, Length=334, Percent_Identity=42.814371257485, Blast_Score=243, Evalue=8e-65,
Organism=Caenorhabditis elegans, GI17568413, Length=334, Percent_Identity=42.814371257485, Blast_Score=243, Evalue=1e-64,
Organism=Saccharomyces cerevisiae, GI6321631, Length=335, Percent_Identity=42.6865671641791, Blast_Score=259, Evalue=4e-70,
Organism=Saccharomyces cerevisiae, GI6322409, Length=329, Percent_Identity=43.4650455927052, Blast_Score=257, Evalue=2e-69,
Organism=Saccharomyces cerevisiae, GI6322468, Length=335, Percent_Identity=42.089552238806, Blast_Score=257, Evalue=2e-69,
Organism=Drosophila melanogaster, GI85725000, Length=330, Percent_Identity=44.8484848484849, Blast_Score=256, Evalue=2e-68,
Organism=Drosophila melanogaster, GI22023983, Length=330, Percent_Identity=44.8484848484849, Blast_Score=256, Evalue=2e-68,
Organism=Drosophila melanogaster, GI17933600, Length=330, Percent_Identity=43.9393939393939, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI18110149, Length=330, Percent_Identity=43.9393939393939, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI19922412, Length=328, Percent_Identity=39.3292682926829, Blast_Score=239, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36018; Mature: 35887

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKVGINGFGRIGRCTLAHIAGSFRNDIEVIKVNATGPIETAAHLIKYDSVHGRFPGQV
CEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCEE
DFSEGRLNLGRGDMQVFSTYDMDTLDWEGCDVVLECTGKFNDGLKAKKHLERGAGKVLLS
ECCCCCEECCCCCEEEEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEE
APGKNVDRTVVYGVNDEDLLSTDKMVSNGSCTTNCLAPLAKVLDEAFGIEHGIMTTIHAY
CCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEE
TGDQPTLDRRHDDLYRARAAAMSMIPTSTGAAKALGEVLPNLKGRLDGSAIRVPTPNVSA
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCEE
VDLTFRAGREVTAEEVNAAVAEASKGHMSRVLGYEPAPLVSTDFNHTEESSIFAPDQTRV
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCEECCCCCEE
VDGRMVRVLAWYDNEWGFSVRMADVATAMGRLN
ECCEEEEEEEEECCCCCEEEEHHHHHHHHHCCC
>Mature Secondary Structure 
TIKVGINGFGRIGRCTLAHIAGSFRNDIEVIKVNATGPIETAAHLIKYDSVHGRFPGQV
EEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCCEE
DFSEGRLNLGRGDMQVFSTYDMDTLDWEGCDVVLECTGKFNDGLKAKKHLERGAGKVLLS
ECCCCCEECCCCCEEEEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEE
APGKNVDRTVVYGVNDEDLLSTDKMVSNGSCTTNCLAPLAKVLDEAFGIEHGIMTTIHAY
CCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEE
TGDQPTLDRRHDDLYRARAAAMSMIPTSTGAAKALGEVLPNLKGRLDGSAIRVPTPNVSA
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCEE
VDLTFRAGREVTAEEVNAAVAEASKGHMSRVLGYEPAPLVSTDFNHTEESSIFAPDQTRV
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCEECCCCCEE
VDGRMVRVLAWYDNEWGFSVRMADVATAMGRLN
ECCEEEEEEEEECCCCCEEEEHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1939098 [H]