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The map label for this gene is mcpA [H]

Identifier: 99080924

GI number: 99080924

Start: 1157674

End: 1159446

Strand: Reverse

Name: mcpA [H]

Synonym: TM1040_1083

Alternate gene names: 99080924

Gene position: 1159446-1157674 (Counterclockwise)

Preceding gene: 99080925

Following gene: 99080923

Centisome position: 36.22

GC content: 62.04

Gene sequence:

>1773_bases
ATGACGAATCTCTCGCTGCGCAAACAAATCTTTGGTTTTGCGGGAATCTTTATCGCGATGATCCTGATCATCGCCGCGAT
TTCGTGGTTTGCAAACCAACGCCTTGCCGGGGCCACCTATCACTATCGCGCGGTCAGCACCCAAAGCAAAAGCTTCGACG
CCATCAAGGAAGACATCGAACAAGGTATCGGCGATCTCTTGTCCTATACCGTCGGCATGCCCGAGGGGCTGAGCGACCTG
CGCGCCAATATCGAAGAGATCCGTAGCGAGCTTGCCGTCGCAGAGGATAATTTCAAATCCACCCCCATCATCGCCGCACG
GGACATGCAGGCCTACGACGCGCTGGTCTCGACCGAGCCGCTTCTGGATCAGCTTGAGGCAACATTGCAGGAGGTAGAGC
GCACCGAAGGCGAGGCGCAGCTGCGCGTGGTCTTTGACAAGGTGTTCCCGCTCGCCGGACAGGTGCGCGATGTGGTGGAT
GCGCTTCAGGACAAACTTGCCGCCACCAGCAAATCCGTCCGCGCAGAGGTCGACTCCCTCATTTTGTTCTGCCAGATCAT
ACAGATCGCCACCAGCGTCGCAGCGGCGCTTGTCGCGGTGACCGTGGCCTTTGTCTTTGGGCGCAAATTGAGCCAACCAG
TGTCTGACGCAGCGCAGAGCATCGCGGCGCTGGCAAAGAAGGACTACGTGGCAGAGATTTCCGGCACTCAGCGCGGCGAC
GAACTCGGTCAGATTGCCCGCAATCTCAAGGATTTGCGCACTCAGCTCGCCGAGGCTGACGCGCATGACCGCCAGAACGC
CGCCGAAAACGCGCGCCGGGTCGAGCTATTTGGCGTCCTCGGTGCCTCCATGAGCGGTCTCAAGAGCGGCGATCTCGACC
AGAACATCGTGGCGCAGGACTGGGAAGACCTCGGCCCCGGTTACGCCACGCTCTGCGAGGATTTCAACGCGCTCTCCTCC
TCGCTTTCGGATCTGGTGGCCCAGCTCAATCAAAGCTCCACCGTCGTGGAACAAAACGCGCGCGAAATGGAACGGATGTC
GGATCAGATGTCGCAGCGCTCCGAGACCCAGGCCGCCACGCTGGAAGAAAGCGCTGCCGCGCTGGAAGAAATGTCGACCG
CCGTGCAATCCAGCGCCGCGCAGGCCAAGGCCGCCGACCGCGAAGTTGAGGAAGGCCGCCGCCGCGCCGAACAGGGCGGC
GAGGTGATGGCGCAGGCGAGCCGCGCCATGGCCTCGATTGCGGAATATTCCAACCGCATCTCCCAGATCATCACCGCGAT
CGACGATATCGCCTTTCAGACCAGTCTGTTGGCGCTCAACGCGGGCGTCGAGGCCGCGCGGGCCGGGGAAGCCGGCCGTG
GCTTTGCGGTGGTGGCCTCCGAAGTGCGCGGACTGGCCATGAAAGCGGCCCATTCTGCAAGTGAAATCAAGCAGTTGGTT
CAGGAAAGCTCCAGCCAGGTCGAAGAGGGAGAGCAGCTGGTACAGGCCACCGCCGAAACCCTGACCCAGATCGTCGAGAG
CGTCACCAATGTCTCTGGCATGGTCTCCGCCATCGCCAGCTCCTCCAGCGAGCAGGCTGCCGGCATCCAGGAAATCAACA
TCGGCGTGGCGCAGCTCGACAAGGCCACGCAGGAAAACGCCGCCATGGTGCAGGAAACCTATTCCGCCAGCCATGAGATG
CGCACCCAGGCCTCCCGCCTCACCAACCTGCTAGAAGGCTTTACCGGTGGGCAGGCAAGCTCTAGCACCGCAGCTCCCGC
CCGCGCGGCCTGA

Upstream 100 bases:

>100_bases
CGTCTTTCCCCTGGGGCAACAACCGAATTTTTACACAGTTTACGGTAGGCTTTCTGCGATGCGCGCGCCTATGCGCCCAT
CTGTATTAAGGGGCCCCCGG

Downstream 100 bases:

>100_bases
TCCGCAAGGCATCTACCGATACATCCCGGCGCATCCTCTGCGCCGGGTGTTTTTTAGGAAACCCTCCTGACAGGGGGGCG
TCGGCCTAAAAACGAACGCG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 590; Mature: 589

Protein sequence:

>590_residues
MTNLSLRKQIFGFAGIFIAMILIIAAISWFANQRLAGATYHYRAVSTQSKSFDAIKEDIEQGIGDLLSYTVGMPEGLSDL
RANIEEIRSELAVAEDNFKSTPIIAARDMQAYDALVSTEPLLDQLEATLQEVERTEGEAQLRVVFDKVFPLAGQVRDVVD
ALQDKLAATSKSVRAEVDSLILFCQIIQIATSVAAALVAVTVAFVFGRKLSQPVSDAAQSIAALAKKDYVAEISGTQRGD
ELGQIARNLKDLRTQLAEADAHDRQNAAENARRVELFGVLGASMSGLKSGDLDQNIVAQDWEDLGPGYATLCEDFNALSS
SLSDLVAQLNQSSTVVEQNAREMERMSDQMSQRSETQAATLEESAAALEEMSTAVQSSAAQAKAADREVEEGRRRAEQGG
EVMAQASRAMASIAEYSNRISQIITAIDDIAFQTSLLALNAGVEAARAGEAGRGFAVVASEVRGLAMKAAHSASEIKQLV
QESSSQVEEGEQLVQATAETLTQIVESVTNVSGMVSAIASSSSEQAAGIQEINIGVAQLDKATQENAAMVQETYSASHEM
RTQASRLTNLLEGFTGGQASSSTAAPARAA

Sequences:

>Translated_590_residues
MTNLSLRKQIFGFAGIFIAMILIIAAISWFANQRLAGATYHYRAVSTQSKSFDAIKEDIEQGIGDLLSYTVGMPEGLSDL
RANIEEIRSELAVAEDNFKSTPIIAARDMQAYDALVSTEPLLDQLEATLQEVERTEGEAQLRVVFDKVFPLAGQVRDVVD
ALQDKLAATSKSVRAEVDSLILFCQIIQIATSVAAALVAVTVAFVFGRKLSQPVSDAAQSIAALAKKDYVAEISGTQRGD
ELGQIARNLKDLRTQLAEADAHDRQNAAENARRVELFGVLGASMSGLKSGDLDQNIVAQDWEDLGPGYATLCEDFNALSS
SLSDLVAQLNQSSTVVEQNAREMERMSDQMSQRSETQAATLEESAAALEEMSTAVQSSAAQAKAADREVEEGRRRAEQGG
EVMAQASRAMASIAEYSNRISQIITAIDDIAFQTSLLALNAGVEAARAGEAGRGFAVVASEVRGLAMKAAHSASEIKQLV
QESSSQVEEGEQLVQATAETLTQIVESVTNVSGMVSAIASSSSEQAAGIQEINIGVAQLDKATQENAAMVQETYSASHEM
RTQASRLTNLLEGFTGGQASSSTAAPARAA
>Mature_589_residues
TNLSLRKQIFGFAGIFIAMILIIAAISWFANQRLAGATYHYRAVSTQSKSFDAIKEDIEQGIGDLLSYTVGMPEGLSDLR
ANIEEIRSELAVAEDNFKSTPIIAARDMQAYDALVSTEPLLDQLEATLQEVERTEGEAQLRVVFDKVFPLAGQVRDVVDA
LQDKLAATSKSVRAEVDSLILFCQIIQIATSVAAALVAVTVAFVFGRKLSQPVSDAAQSIAALAKKDYVAEISGTQRGDE
LGQIARNLKDLRTQLAEADAHDRQNAAENARRVELFGVLGASMSGLKSGDLDQNIVAQDWEDLGPGYATLCEDFNALSSS
LSDLVAQLNQSSTVVEQNAREMERMSDQMSQRSETQAATLEESAAALEEMSTAVQSSAAQAKAADREVEEGRRRAEQGGE
VMAQASRAMASIAEYSNRISQIITAIDDIAFQTSLLALNAGVEAARAGEAGRGFAVVASEVRGLAMKAAHSASEIKQLVQ
ESSSQVEEGEQLVQATAETLTQIVESVTNVSGMVSAIASSSSEQAAGIQEINIGVAQLDKATQENAAMVQETYSASHEMR
TQASRLTNLLEGFTGGQASSSTAAPARAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=282, Percent_Identity=40.4255319148936, Blast_Score=188, Evalue=6e-49,
Organism=Escherichia coli, GI1788194, Length=302, Percent_Identity=37.4172185430464, Blast_Score=179, Evalue=7e-46,
Organism=Escherichia coli, GI2367378, Length=264, Percent_Identity=39.0151515151515, Blast_Score=176, Evalue=5e-45,
Organism=Escherichia coli, GI1787690, Length=288, Percent_Identity=36.4583333333333, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI1789453, Length=232, Percent_Identity=38.3620689655172, Blast_Score=160, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 62833; Mature: 62702

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TNLSLRKQIFGFAGIFIAMILIIAAISWFANQRLAGATYHYRAVSTQSKSFDAIKEDIE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCHHHHHHHHHHH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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]