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The map label for this gene is pitA [C]

Identifier: 99080508

GI number: 99080508

Start: 713370

End: 714860

Strand: Reverse

Name: pitA [C]

Synonym: TM1040_0667

Alternate gene names: 99080508

Gene position: 714860-713370 (Counterclockwise)

Preceding gene: 99080509

Following gene: 99080505

Centisome position: 22.33

GC content: 61.37

Gene sequence:

>1491_bases
ATGACACAGCCGGACTGGAGATCACTGGACAAGGACCTAGTGCGCCTTAACCAGACGGAGCGGACCACAGGCTATGTGGT
GCGCCCGCTCCTCGGGTTTGGCCTGGCGCTGACCTTCATGGCTTTGGCTGGTGTTGAAGCGGCCTTTGTACTGGGGACAT
CCCAAACCACGATGATGGCAATGGTCGCAGCCATGTTCGGCGCGTATCTCGCACTCAACATCGGGGCCAATGATGTGGCC
AACAACATGGGTCCCGCTGTCGGCGCTAAGGCGCTACCGATGACCGCAGCCTTGATTGCTGCCGCCTTGGCCGAGGTTAC
AGGCGCGCTTCTGGGAGGCAGCGAGGTGGTGGCAACCGTCTCTACCCGCCTGATCGAGCCGGACGCCATGAGCGCGCCGC
ATATGCTCATTCAGGCGATGATGTCGGCCATGATTGCATCCGCTCTCTGGGTCAATCTGGCCACATGGATGGGGGCGCCG
GTTTCCACAACACAGAGCATCATTGGTGCCATTCTAGGTGCGACAACAGCGGCGGCCGGTTTTGGCGCGGTGGATTGGCT
GACCTTTGGCAGCATCGCCACAAGCTGGATGCTTTCTCCGCTGATCGGGGCCGTGCTTGCGATGGCGCTCCTCGCCCTGA
TCCGACAGGTGATCACCGAGCAGGATGAAAAGCTCGAAGCCGCGCGCCGGTGGGTGCCGATCCTGCTGGCCGGTATGGGG
GGCGCATTTGGGACGTTCTTCGTGCTCAAGCTGCCTGAAACCGTTGCCGCCGCAACCTCTGCCCAAGCCCTGCTGGCGGG
CGGTTGCCTCGGGCTGTTGTCCTTTGTGATTGCTCGGCCGCTCATTCTGCGCCGCGCCGCAGAGCTTGAGAACCAAAAGG
GCGCGATAAAGGCCCTGTTCCGCCTGCCCCTTGTGATCGCCGCGATCCTGATGTCCTTTGCGCATGGGGCCAATGATGTG
GCAAATGCCATCGGCCCGCTTGCCAGCATCGTGCAGGCAATGGATCTGGAAAACACCGGCTCACACCCAGCCGAAATCAA
TGCGTTCACCACTCTTGATGTGCCTGTCTGGGTTCTGATCATCGGAGCGTTTGGCATGGCAATGGGTGTGGTTCTGTTTG
GTCCCAGATTGGTGAACATGGTGGGCAACCAGATCACCAAGCTGAACCCGATCCGGGCCTATTGCGTGTCCACGTCTGCC
GCGCTCACGGTCATCATGGCCAGTTGGTTGGGTCTGCCGGTATCGTCGACCCATGTGGCCGTCGGCGCCGTCTTTGGGGT
TGGATTCTACCGCGAGCACGCCGCAGCACAGGCGCGCCGCGCAGGCCAGAAGGAGACCCGACCCGGCCTGCCTCACGAAG
ATCGCAGCCGCCGTCGACTGGTGCGCCGCAGCCATGTTCTGACAATCTTGGCAGCCTGGCTCATTACCGTGCCGCTTTCT
GGTTTGCTGTCAGCGGGCATCTACGGGATCTTGCATCTGTTTTCTGGCTAA

Upstream 100 bases:

>100_bases
CCGAGACTGTATCCTTTTGCATCGCGCGCGGGCCTCTCCCACGCCAGCGCGCAAAGCAGTGCGCAAGGCAGGAACTCGCA
GTGATTGACGGGGGCGCGCG

Downstream 100 bases:

>100_bases
CGAGAGAGTGCAAGCGGGGCATCCGGCCTCCACGGCGTGCCCGATGCTCATGCTCTTTTGTTTGTCATGTCAGCGCTGAA
GCAGCCTGTTGAGACGCCGA

Product: phosphate transporter

Products: Proton [Cytoplasm]; phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 495

Protein sequence:

>496_residues
MTQPDWRSLDKDLVRLNQTERTTGYVVRPLLGFGLALTFMALAGVEAAFVLGTSQTTMMAMVAAMFGAYLALNIGANDVA
NNMGPAVGAKALPMTAALIAAALAEVTGALLGGSEVVATVSTRLIEPDAMSAPHMLIQAMMSAMIASALWVNLATWMGAP
VSTTQSIIGAILGATTAAAGFGAVDWLTFGSIATSWMLSPLIGAVLAMALLALIRQVITEQDEKLEAARRWVPILLAGMG
GAFGTFFVLKLPETVAAATSAQALLAGGCLGLLSFVIARPLILRRAAELENQKGAIKALFRLPLVIAAILMSFAHGANDV
ANAIGPLASIVQAMDLENTGSHPAEINAFTTLDVPVWVLIIGAFGMAMGVVLFGPRLVNMVGNQITKLNPIRAYCVSTSA
ALTVIMASWLGLPVSSTHVAVGAVFGVGFYREHAAAQARRAGQKETRPGLPHEDRSRRRLVRRSHVLTILAAWLITVPLS
GLLSAGIYGILHLFSG

Sequences:

>Translated_496_residues
MTQPDWRSLDKDLVRLNQTERTTGYVVRPLLGFGLALTFMALAGVEAAFVLGTSQTTMMAMVAAMFGAYLALNIGANDVA
NNMGPAVGAKALPMTAALIAAALAEVTGALLGGSEVVATVSTRLIEPDAMSAPHMLIQAMMSAMIASALWVNLATWMGAP
VSTTQSIIGAILGATTAAAGFGAVDWLTFGSIATSWMLSPLIGAVLAMALLALIRQVITEQDEKLEAARRWVPILLAGMG
GAFGTFFVLKLPETVAAATSAQALLAGGCLGLLSFVIARPLILRRAAELENQKGAIKALFRLPLVIAAILMSFAHGANDV
ANAIGPLASIVQAMDLENTGSHPAEINAFTTLDVPVWVLIIGAFGMAMGVVLFGPRLVNMVGNQITKLNPIRAYCVSTSA
ALTVIMASWLGLPVSSTHVAVGAVFGVGFYREHAAAQARRAGQKETRPGLPHEDRSRRRLVRRSHVLTILAAWLITVPLS
GLLSAGIYGILHLFSG
>Mature_495_residues
TQPDWRSLDKDLVRLNQTERTTGYVVRPLLGFGLALTFMALAGVEAAFVLGTSQTTMMAMVAAMFGAYLALNIGANDVAN
NMGPAVGAKALPMTAALIAAALAEVTGALLGGSEVVATVSTRLIEPDAMSAPHMLIQAMMSAMIASALWVNLATWMGAPV
STTQSIIGAILGATTAAAGFGAVDWLTFGSIATSWMLSPLIGAVLAMALLALIRQVITEQDEKLEAARRWVPILLAGMGG
AFGTFFVLKLPETVAAATSAQALLAGGCLGLLSFVIARPLILRRAAELENQKGAIKALFRLPLVIAAILMSFAHGANDVA
NAIGPLASIVQAMDLENTGSHPAEINAFTTLDVPVWVLIIGAFGMAMGVVLFGPRLVNMVGNQITKLNPIRAYCVSTSAA
LTVIMASWLGLPVSSTHVAVGAVFGVGFYREHAAAQARRAGQKETRPGLPHEDRSRRRLVRRSHVLTILAAWLITVPLSG
LLSAGIYGILHLFSG

Specific function: Potential transporter for phosphate [H]

COG id: COG0306

COG function: function code P; Phosphate/sulphate permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family [H]

Homologues:

Organism=Homo sapiens, GI31543630, Length=203, Percent_Identity=32.512315270936, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI5803173, Length=201, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71981576, Length=481, Percent_Identity=27.6507276507277, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17539280, Length=211, Percent_Identity=34.5971563981043, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI25146401, Length=198, Percent_Identity=33.8383838383838, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI32566716, Length=168, Percent_Identity=31.547619047619, Blast_Score=92, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17536725, Length=215, Percent_Identity=27.906976744186, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17557328, Length=133, Percent_Identity=35.3383458646617, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319773, Length=277, Percent_Identity=25.9927797833935, Blast_Score=97, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21356511, Length=215, Percent_Identity=32.5581395348837, Blast_Score=113, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001204 [H]

Pfam domain/function: PF01384 PHO4 [H]

EC number: NA

Molecular weight: Translated: 51858; Mature: 51727

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQPDWRSLDKDLVRLNQTERTTGYVVRPLLGFGLALTFMALAGVEAAFVLGTSQTTMMA
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCHHHHHH
MVAAMFGAYLALNIGANDVANNMGPAVGAKALPMTAALIAAALAEVTGALLGGSEVVATV
HHHHHHHHHHEEECCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
STRLIEPDAMSAPHMLIQAMMSAMIASALWVNLATWMGAPVSTTQSIIGAILGATTAAAG
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
FGAVDWLTFGSIATSWMLSPLIGAVLAMALLALIRQVITEQDEKLEAARRWVPILLAGMG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
GAFGTFFVLKLPETVAAATSAQALLAGGCLGLLSFVIARPLILRRAAELENQKGAIKALF
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
RLPLVIAAILMSFAHGANDVANAIGPLASIVQAMDLENTGSHPAEINAFTTLDVPVWVLI
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECHHHHHHHH
IGAFGMAMGVVLFGPRLVNMVGNQITKLNPIRAYCVSTSAALTVIMASWLGLPVSSTHVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
VGAVFGVGFYREHAAAQARRAGQKETRPGLPHEDRSRRRLVRRSHVLTILAAWLITVPLS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLLSAGIYGILHLFSG
HHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQPDWRSLDKDLVRLNQTERTTGYVVRPLLGFGLALTFMALAGVEAAFVLGTSQTTMMA
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCHHHHHH
MVAAMFGAYLALNIGANDVANNMGPAVGAKALPMTAALIAAALAEVTGALLGGSEVVATV
HHHHHHHHHHEEECCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
STRLIEPDAMSAPHMLIQAMMSAMIASALWVNLATWMGAPVSTTQSIIGAILGATTAAAG
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
FGAVDWLTFGSIATSWMLSPLIGAVLAMALLALIRQVITEQDEKLEAARRWVPILLAGMG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
GAFGTFFVLKLPETVAAATSAQALLAGGCLGLLSFVIARPLILRRAAELENQKGAIKALF
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
RLPLVIAAILMSFAHGANDVANAIGPLASIVQAMDLENTGSHPAEINAFTTLDVPVWVLI
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECHHHHHHHH
IGAFGMAMGVVLFGPRLVNMVGNQITKLNPIRAYCVSTSAALTVIMASWLGLPVSSTHVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
VGAVFGVGFYREHAAAQARRAGQKETRPGLPHEDRSRRRLVRRSHVLTILAAWLITVPLS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLLSAGIYGILHLFSG
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + phosphate [Periplasm] = Proton [Cytoplasm] + phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]