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The map label for this gene is groES [H]

Identifier: 99080437

GI number: 99080437

Start: 637635

End: 637922

Strand: Direct

Name: groES [H]

Synonym: TM1040_0596

Alternate gene names: 99080437

Gene position: 637635-637922 (Clockwise)

Preceding gene: 99080436

Following gene: 99080438

Centisome position: 19.92

GC content: 57.64

Gene sequence:

>288_bases
ATGGCATTGAAACCGCTTCATGACCGTGTGCTGGTTCGCCGTACCGAAAGCGAAGAAAAAACCGCAGGTGGTCTGATCAT
TCCCGACAGCGCCAAGGAAAAACCGTCCGAGGGCGTTGTTGTCGCGTGTGGCGAAGGCGCGCGCAAGGACAGCGGCGAGC
TGATCGCGATGGCCGTGAAAGAGGGTGACAACATCCTGTTCGGCAAATGGTCCGGCACCGAAGTCACCGTCGACGGCGAA
GAGCTGCTGATGATGAAAGAGAGCGACATCATGGGTGTGATCGTCTGA

Upstream 100 bases:

>100_bases
CCGCAGTTAGCACTCGACTGAGGTGAGTGCTAACGTCTCCGCGGCCCATGATGGGCGTGGGGAAAGGAAAACACTTTGAG
CCTTTTGAGGAGCTGCAAAG

Downstream 100 bases:

>100_bases
GCCTCGCTCCGACACATCCCACATCGCGTAACAAGACAGTATTCTCAAGGAGACTGAATAATGGCTGCTAAGGACGTCAA
ATTCGACACCGATGCCCGCA

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10 [H]

Number of amino acids: Translated: 95; Mature: 94

Protein sequence:

>95_residues
MALKPLHDRVLVRRTESEEKTAGGLIIPDSAKEKPSEGVVVACGEGARKDSGELIAMAVKEGDNILFGKWSGTEVTVDGE
ELLMMKESDIMGVIV

Sequences:

>Translated_95_residues
MALKPLHDRVLVRRTESEEKTAGGLIIPDSAKEKPSEGVVVACGEGARKDSGELIAMAVKEGDNILFGKWSGTEVTVDGE
ELLMMKESDIMGVIV
>Mature_94_residues
ALKPLHDRVLVRRTESEEKTAGGLIIPDSAKEKPSEGVVVACGEGARKDSGELIAMAVKEGDNILFGKWSGTEVTVDGEE
LLMMKESDIMGVIV

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter [H]

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family [H]

Homologues:

Organism=Homo sapiens, GI4504523, Length=91, Percent_Identity=37.3626373626374, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790585, Length=95, Percent_Identity=42.1052631578947, Blast_Score=79, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17555568, Length=93, Percent_Identity=44.0860215053763, Blast_Score=90, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6324594, Length=91, Percent_Identity=34.0659340659341, Blast_Score=62, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356029, Length=90, Percent_Identity=43.3333333333333, Blast_Score=75, Evalue=6e-15,
Organism=Drosophila melanogaster, GI21358317, Length=89, Percent_Identity=42.6966292134831, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032 [H]

Pfam domain/function: PF00166 Cpn10 [H]

EC number: NA

Molecular weight: Translated: 10171; Mature: 10040

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALKPLHDRVLVRRTESEEKTAGGLIIPDSAKEKPSEGVVVACGEGARKDSGELIAMAVK
CCCCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEE
EGDNILFGKWSGTEVTVDGEELLMMKESDIMGVIV
CCCEEEEEECCCCEEEECHHHEEEEECCCEEEEEC
>Mature Secondary Structure 
ALKPLHDRVLVRRTESEEKTAGGLIIPDSAKEKPSEGVVVACGEGARKDSGELIAMAVK
CCCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEE
EGDNILFGKWSGTEVTVDGEELLMMKESDIMGVIV
CCCEEEEEECCCCEEEECHHHEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA