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The map label for this gene is 99080405

Identifier: 99080405

GI number: 99080405

Start: 600959

End: 602131

Strand: Reverse

Name: 99080405

Synonym: TM1040_0564

Alternate gene names: NA

Gene position: 602131-600959 (Counterclockwise)

Preceding gene: 99080408

Following gene: 99080402

Centisome position: 18.81

GC content: 60.7

Gene sequence:

>1173_bases
ATGCCAGCCTTTGCAAGATGGATCAAACGCCTCGTGGGTCTCGCCATATGTGCGATTATGGCGTTTTTTATCTTCGCTCC
GGCGGCTCTCGACCGCCAGCGCAACCCCGTTGCAGAGCATGACTCTTATCCGATCAGCGACGCAGCACGTGACCTGCACC
AAAGCCTCATCATCGGCGATCTGCACGCAGACCCGCTGCTGTGGAAACGTGACCTGACCAAGCGCAACGCGCGCGGCCAT
GTGGACATCCCCCGGCTGATCGAGGGCAATGTCACCTTGCAGGTCTTCACCGCTGTGACCAAATCCCCCGCCGGGCAGAA
CTATGACCATAATGATGCGGATGCGCGGGACAACATCACGCTGCTTGCGATCGGTCAGCTTTGGCCCCTTCCCACCTGGA
CGTCGCTCTATGAACGCGCCCTGCATCAAGCCGAGAAGTTGCACCGGTTCCAGGAACGCTCCGAAGGGCGGCTGCGTATC
ATTCGTACTGAGGCCGATCTCGACATTCTGCTGGAGCGCAAACGCGCAGGTCACGAAGTCGTCGGTGGGCTTTTGGGCAT
CGAGGGCGCACACCCGCTGGAGGGCGACATCAGTAAACTGCAAGGCCTAGAGGAGGCCGGATACCGCCTGATCGCGCTGC
AGCATTTCTTTGACAATGCGCTTGGGGGTTCGTTGCATGGCGCAGGCGATCTGGGTCTCTCGGCGTTTGGGCGCGACGTG
GTTTCGGAGTCGGTTGATCGCGGCTTGATCCTGGATCTTGCACATTCCAGCCCGCAGGTGGTGCGGGATGTCATTGCGAT
GACCGATGTCCCGTTGGTTCTGTCGCACACCGGCATCCACAAGGCCTGCCCCGTAAAGCGAAACCTACCGGACGCCCTGA
TGCGCGACATCGCCGCTACGGGCGGGGTGATCGGAATTGGCTACTGGGCAGATGCCGTGTGTGATGCCTCCCCCAGTGGG
ATCGCCCGTGCCATTCACAGCGCCATCGAGGTGGTTGGAGAAAACCACGTTGCCCTTGGTTCAGACTTTGACGGCTCTGT
TGCGACGACTTTCGACAGCTCCGAACTTGCTGCGCTAACCCAGGCCATGCTCGATGAGGGGCTGAGCGAGACCCAAATCC
GCAAAGTCGCCGGGGAGAACATGTTGCGCGTCCTGCGCGCACGCCTCGACTGA

Upstream 100 bases:

>100_bases
CAAACATCTCGATGCCGTGGCGCGAGGCGCGAGACAAGAGGGTTGCGTTTGTGCTGTTGCACCGTAGCCTGCCTACAAAC
CAAATGTCAGGATCTCCTCC

Downstream 100 bases:

>100_bases
GTGCAAAGCATGCCTTTGGCAGAGCGCCTTTGCACGGGCGCAACCAGAAACCCGACAACAATAGTCAACTATTTGATTTG
GTTGAGTTTTTTATTGACCT

Product: peptidase M19, renal dipeptidase

Products: NA

Alternate protein names: ORF X [H]

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MPAFARWIKRLVGLAICAIMAFFIFAPAALDRQRNPVAEHDSYPISDAARDLHQSLIIGDLHADPLLWKRDLTKRNARGH
VDIPRLIEGNVTLQVFTAVTKSPAGQNYDHNDADARDNITLLAIGQLWPLPTWTSLYERALHQAEKLHRFQERSEGRLRI
IRTEADLDILLERKRAGHEVVGGLLGIEGAHPLEGDISKLQGLEEAGYRLIALQHFFDNALGGSLHGAGDLGLSAFGRDV
VSESVDRGLILDLAHSSPQVVRDVIAMTDVPLVLSHTGIHKACPVKRNLPDALMRDIAATGGVIGIGYWADAVCDASPSG
IARAIHSAIEVVGENHVALGSDFDGSVATTFDSSELAALTQAMLDEGLSETQIRKVAGENMLRVLRARLD

Sequences:

>Translated_390_residues
MPAFARWIKRLVGLAICAIMAFFIFAPAALDRQRNPVAEHDSYPISDAARDLHQSLIIGDLHADPLLWKRDLTKRNARGH
VDIPRLIEGNVTLQVFTAVTKSPAGQNYDHNDADARDNITLLAIGQLWPLPTWTSLYERALHQAEKLHRFQERSEGRLRI
IRTEADLDILLERKRAGHEVVGGLLGIEGAHPLEGDISKLQGLEEAGYRLIALQHFFDNALGGSLHGAGDLGLSAFGRDV
VSESVDRGLILDLAHSSPQVVRDVIAMTDVPLVLSHTGIHKACPVKRNLPDALMRDIAATGGVIGIGYWADAVCDASPSG
IARAIHSAIEVVGENHVALGSDFDGSVATTFDSSELAALTQAMLDEGLSETQIRKVAGENMLRVLRARLD
>Mature_389_residues
PAFARWIKRLVGLAICAIMAFFIFAPAALDRQRNPVAEHDSYPISDAARDLHQSLIIGDLHADPLLWKRDLTKRNARGHV
DIPRLIEGNVTLQVFTAVTKSPAGQNYDHNDADARDNITLLAIGQLWPLPTWTSLYERALHQAEKLHRFQERSEGRLRII
RTEADLDILLERKRAGHEVVGGLLGIEGAHPLEGDISKLQGLEEAGYRLIALQHFFDNALGGSLHGAGDLGLSAFGRDVV
SESVDRGLILDLAHSSPQVVRDVIAMTDVPLVLSHTGIHKACPVKRNLPDALMRDIAATGGVIGIGYWADAVCDASPSGI
ARAIHSAIEVVGENHVALGSDFDGSVATTFDSSELAALTQAMLDEGLSETQIRKVAGENMLRVLRARLD

Specific function: Unknown

COG id: COG2355

COG function: function code E; Zn-dependent dipeptidase, microsomal dipeptidase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M19 family [H]

Homologues:

Organism=Homo sapiens, GI189458885, Length=356, Percent_Identity=25, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI4758190, Length=356, Percent_Identity=25, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI11641269, Length=243, Percent_Identity=27.5720164609054, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI193211608, Length=325, Percent_Identity=23.0769230769231, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI193211610, Length=325, Percent_Identity=23.0769230769231, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI161083233, Length=398, Percent_Identity=26.8844221105528, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI281362638, Length=326, Percent_Identity=26.9938650306748, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281362636, Length=326, Percent_Identity=26.9938650306748, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI221475880, Length=400, Percent_Identity=24.75, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008257 [H]

Pfam domain/function: PF01244 Peptidase_M19 [H]

EC number: NA

Molecular weight: Translated: 42393; Mature: 42262

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAFARWIKRLVGLAICAIMAFFIFAPAALDRQRNPVAEHDSYPISDAARDLHQSLIIGD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
LHADPLLWKRDLTKRNARGHVDIPRLIEGNVTLQVFTAVTKSPAGQNYDHNDADARDNIT
CCCCCHHHHHHHHHCCCCCCCCCCHHHCCCCEEEEEEHHHCCCCCCCCCCCCCCCCCCEE
LLAIGQLWPLPTWTSLYERALHQAEKLHRFQERSEGRLRIIRTEADLDILLERKRAGHEV
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCHHH
VGGLLGIEGAHPLEGDISKLQGLEEAGYRLIALQHFFDNALGGSLHGAGDLGLSAFGRDV
HHHHHCCCCCCCCCCCHHHHCCHHHCCCEEEHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
VSESVDRGLILDLAHSSPQVVRDVIAMTDVPLVLSHTGIHKACPVKRNLPDALMRDIAAT
HHHHHCCCEEEEECCCCHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHC
GGVIGIGYWADAVCDASPSGIARAIHSAIEVVGENHVALGSDFDGSVATTFDSSELAALT
CCEEEECHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCEEEECCCHHHHHHH
QAMLDEGLSETQIRKVAGENMLRVLRARLD
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PAFARWIKRLVGLAICAIMAFFIFAPAALDRQRNPVAEHDSYPISDAARDLHQSLIIGD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
LHADPLLWKRDLTKRNARGHVDIPRLIEGNVTLQVFTAVTKSPAGQNYDHNDADARDNIT
CCCCCHHHHHHHHHCCCCCCCCCCHHHCCCCEEEEEEHHHCCCCCCCCCCCCCCCCCCEE
LLAIGQLWPLPTWTSLYERALHQAEKLHRFQERSEGRLRIIRTEADLDILLERKRAGHEV
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCHHH
VGGLLGIEGAHPLEGDISKLQGLEEAGYRLIALQHFFDNALGGSLHGAGDLGLSAFGRDV
HHHHHCCCCCCCCCCCHHHHCCHHHCCCEEEHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
VSESVDRGLILDLAHSSPQVVRDVIAMTDVPLVLSHTGIHKACPVKRNLPDALMRDIAAT
HHHHHCCCEEEEECCCCHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHC
GGVIGIGYWADAVCDASPSGIARAIHSAIEVVGENHVALGSDFDGSVATTFDSSELAALT
CCEEEECHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCEEEECCCHHHHHHH
QAMLDEGLSETQIRKVAGENMLRVLRARLD
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1313537 [H]