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The map label for this gene is pcaH [H]

Identifier: 99080399

GI number: 99080399

Start: 595135

End: 595857

Strand: Reverse

Name: pcaH [H]

Synonym: TM1040_0558

Alternate gene names: 99080399

Gene position: 595857-595135 (Counterclockwise)

Preceding gene: 99080400

Following gene: 99080398

Centisome position: 18.62

GC content: 61.41

Gene sequence:

>723_bases
ATGAGCAACGGATATGTAAATCGCGACCGACGCTGGCATCCCCCCAGCATCACGCCCGATTATAAAACCTCCGTCGCGCG
CGGGCCGCGCCATGCGCCCTTGTCCTTTCCCACCACTTTGGTCGAGGAAACCGGGCCTGTCTTTGGCCACGAGATCCTGG
GCCCGCGCGACAACGACCTGATCCTCAATTTTGCCAAGGACGGCGGCATGGCGATCGGCCCGCGTATCATTGTGCACGGG
CAGCTGCGCGATGAATTTGGCCGTGGCGTTCCCGGCGCGCTGATCGAGGTCTGGCAGGCCAATGCAGGCGGTCGCTACCG
CCACAAGAAGGAAAGCTATCTTGCGCCGCTCGATCCCAATTTTGGTGGCTGCGGGCGCTGCATCACGGACGCAGAGGGGT
TTTACGAGTTCCGCACCATCATGCCAGGCCCCTACCCCTGGCCCAATACCATGAACGACTGGCGCCCCGCGCATATCCAT
TTCTCGATCTTTGGCGCGAGCTTTGCCCAGCGCCTCATCACCCAGATGTATTTCGAGGGAGATCCGCTCATTTGGCGCTG
CCCAATCGTGGATACGATCCCCACGCGCGAAGCGATTGAAAGCCTCGTGGCGCCCCTTGATATGGCGCGCACCGTGCCGA
TGGACGCGCGTGCCTATAAATTCGACATCACCCTGCGCGGCCGCCGCCAGACCCTGTTTGAAAATCGCATGGAGGGGCTT
TGA

Upstream 100 bases:

>100_bases
TTCAGCATGTCGCGGTCTATGCAGGGGTGCCACGCGCAAATCATGCGCTGAAACTGGCCAAGGAAACCTATGCCGAAATG
GACCGGGAGGACCAACAGTC

Downstream 100 bases:

>100_bases
TCATGGTACAACCTCTGACGCACCTCAAGGAATCCCCGTCTCAGACGGCTGGCCCCTATGTACATATTGGCTGTACACCG
AATTTTGCTGACATCGCCGG

Product: protocatechuate 3,4-dioxygenase, beta subunit

Products: NA

Alternate protein names: 3,4-PCD [H]

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MSNGYVNRDRRWHPPSITPDYKTSVARGPRHAPLSFPTTLVEETGPVFGHEILGPRDNDLILNFAKDGGMAIGPRIIVHG
QLRDEFGRGVPGALIEVWQANAGGRYRHKKESYLAPLDPNFGGCGRCITDAEGFYEFRTIMPGPYPWPNTMNDWRPAHIH
FSIFGASFAQRLITQMYFEGDPLIWRCPIVDTIPTREAIESLVAPLDMARTVPMDARAYKFDITLRGRRQTLFENRMEGL

Sequences:

>Translated_240_residues
MSNGYVNRDRRWHPPSITPDYKTSVARGPRHAPLSFPTTLVEETGPVFGHEILGPRDNDLILNFAKDGGMAIGPRIIVHG
QLRDEFGRGVPGALIEVWQANAGGRYRHKKESYLAPLDPNFGGCGRCITDAEGFYEFRTIMPGPYPWPNTMNDWRPAHIH
FSIFGASFAQRLITQMYFEGDPLIWRCPIVDTIPTREAIESLVAPLDMARTVPMDARAYKFDITLRGRRQTLFENRMEGL
>Mature_239_residues
SNGYVNRDRRWHPPSITPDYKTSVARGPRHAPLSFPTTLVEETGPVFGHEILGPRDNDLILNFAKDGGMAIGPRIIVHGQ
LRDEFGRGVPGALIEVWQANAGGRYRHKKESYLAPLDPNFGGCGRCITDAEGFYEFRTIMPGPYPWPNTMNDWRPAHIHF
SIFGASFAQRLITQMYFEGDPLIWRCPIVDTIPTREAIESLVAPLDMARTVPMDARAYKFDITLRGRRQTLFENRMEGL

Specific function: Plays an essential role in the utilization of numerous aromatic and hydroaromatic compounds via the beta-ketoadipate pathway [H]

COG id: COG3485

COG function: function code Q; Protocatechuate 3,4-dioxygenase beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the intradiol ring-cleavage dioxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000627
- InterPro:   IPR015889
- InterPro:   IPR012785 [H]

Pfam domain/function: PF00775 Dioxygenase_C [H]

EC number: =1.13.11.3 [H]

Molecular weight: Translated: 27172; Mature: 27041

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: PS00083 INTRADIOL_DIOXYGENAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNGYVNRDRRWHPPSITPDYKTSVARGPRHAPLSFPTTLVEETGPVFGHEILGPRDNDL
CCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHCCCCCCHHHCCCCCCCE
ILNFAKDGGMAIGPRIIVHGQLRDEFGRGVPGALIEVWQANAGGRYRHKKESYLAPLDPN
EEEEECCCCEEECCEEEEECCHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHCCCCCCCCC
FGGCGRCITDAEGFYEFRTIMPGPYPWPNTMNDWRPAHIHFSIFGASFAQRLITQMYFEG
CCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHCCC
DPLIWRCPIVDTIPTREAIESLVAPLDMARTVPMDARAYKFDITLRGRRQTLFENRMEGL
CCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHCCC
>Mature Secondary Structure 
SNGYVNRDRRWHPPSITPDYKTSVARGPRHAPLSFPTTLVEETGPVFGHEILGPRDNDL
CCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHCCCCCCHHHCCCCCCCE
ILNFAKDGGMAIGPRIIVHGQLRDEFGRGVPGALIEVWQANAGGRYRHKKESYLAPLDPN
EEEEECCCCEEECCEEEEECCHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHCCCCCCCCC
FGGCGRCITDAEGFYEFRTIMPGPYPWPNTMNDWRPAHIHFSIFGASFAQRLITQMYFEG
CCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHCCC
DPLIWRCPIVDTIPTREAIESLVAPLDMARTVPMDARAYKFDITLRGRRQTLFENRMEGL
CCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407791; 115853; 3194022; 7990141; 9254599; 9254600; 9298971 [H]