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The map label for this gene is pcaB [H]

Identifier: 99080396

GI number: 99080396

Start: 592559

End: 593632

Strand: Reverse

Name: pcaB [H]

Synonym: TM1040_0555

Alternate gene names: 99080396

Gene position: 593632-592559 (Counterclockwise)

Preceding gene: 99080397

Following gene: 99080391

Centisome position: 18.55

GC content: 63.31

Gene sequence:

>1074_bases
GTGAATCCGCTGACCTCATCGAACCCCTATTTTGCAGGCCTTTTTGCCGACCAGGAAATCACGGCCTTGTTTGAAGGGGC
GGCCACGGCAGACGCGTTCTTGGCGTATGAGATGGCCCTGACCCGTGCCGCCGCAGAGGTTGGGCAGATCGACATCGGTC
TGGCGCAGCGTGCGCTGGCGGCCATGGTAGATTTCACCCCCGATGTTGCGGAGCTTCAGAGCGATCTCTCAGCCGACGGC
ATGGCGGTGCCCGGATATGTGCGTCAACTCAAGGCCCATGTCGGCGCCGAATGTGTCGCCGCCGTGCATCCGGGGGCTAC
CAGTCAGGACTTGATAGACACTGCACAGGCCTTGGCTCTTCGCGCCGCAAACGAAATTTATATCTCGCGCCTCACCACGC
TGATCGACGCGCTGCGCGATCTGGAAGAAACCCATGGCGATAATCGCCTGATGGGGCGCACCCGGATGCAGGCGGCGCTG
CCGATCTCCGCCGGACATCGGATCTCAAGCTGGATCTCACCGCTCGTGCGTCATACCTCCCGGCTGGAGATACTGCGCCC
CGAGGTAGAAGCCCTGCAATTTGGTGGCCCGGTTGGCGACGGGCAGCGCAGCCAGCCCCATGCCGCCGCCATGGCCGACC
ACATGGGAAAGGCACTGGGGCTCCGCGCGCCTGAACGCTGCTGGCACACGGAGCGCGACTCATTGGTCACATATGCCGGA
TGGCTTTCTGCGCTTACCGGCAGTCTGGGCAAATTCGGCCAAGACGTGTGTTTGATGGTGCAACAGGGTGTGGATGCGCT
CGCGCAGGCCGGAGGCGGCAGCAGTTCTGCCATGGCGCACAAGCAAAACCCGGTTACCGCAGAGATGCTGGTGACGCTCT
CACGCTACAACGCCGGACAGGTTGCCCTGATGCATCAGGCCTCCGTGCATGAACAGGAGCGCTCGGGCGCCATGTGGACG
CTTGAGTGGATGGTTCTGCCGGCAATGATGACCTGCACCGGAGCCGCACTCCGCCTCGCAACCCGGCAGGTGCAGGCAAT
CACGCGCATCGGCGAGCCTCCCACCACGCGTTGA

Upstream 100 bases:

>100_bases
GCGCCCCGTCGCCACCTGGCAACAGGCCAGAGAGATCCTTGACGTGCCATTGCGGGCCTGATCTGCTGTTCTGACTCCGC
TTCGAAGGACCGTGCCACCT

Downstream 100 bases:

>100_bases
CCCGCGCGGTCCGTCTTCACTTCTCGCACAGAGCCGATTTTTACGCTCGAAAACCAGCGACTCTGCTCTTGGCCTGCCCC
TGCCGTACCCGATTCACTCA

Product: 3-carboxy-cis,cis-muconate cycloisomerase

Products: NA

Alternate protein names: 3-carboxymuconate lactonizing enzyme; CMLE [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MNPLTSSNPYFAGLFADQEITALFEGAATADAFLAYEMALTRAAAEVGQIDIGLAQRALAAMVDFTPDVAELQSDLSADG
MAVPGYVRQLKAHVGAECVAAVHPGATSQDLIDTAQALALRAANEIYISRLTTLIDALRDLEETHGDNRLMGRTRMQAAL
PISAGHRISSWISPLVRHTSRLEILRPEVEALQFGGPVGDGQRSQPHAAAMADHMGKALGLRAPERCWHTERDSLVTYAG
WLSALTGSLGKFGQDVCLMVQQGVDALAQAGGGSSSAMAHKQNPVTAEMLVTLSRYNAGQVALMHQASVHEQERSGAMWT
LEWMVLPAMMTCTGAALRLATRQVQAITRIGEPPTTR

Sequences:

>Translated_357_residues
MNPLTSSNPYFAGLFADQEITALFEGAATADAFLAYEMALTRAAAEVGQIDIGLAQRALAAMVDFTPDVAELQSDLSADG
MAVPGYVRQLKAHVGAECVAAVHPGATSQDLIDTAQALALRAANEIYISRLTTLIDALRDLEETHGDNRLMGRTRMQAAL
PISAGHRISSWISPLVRHTSRLEILRPEVEALQFGGPVGDGQRSQPHAAAMADHMGKALGLRAPERCWHTERDSLVTYAG
WLSALTGSLGKFGQDVCLMVQQGVDALAQAGGGSSSAMAHKQNPVTAEMLVTLSRYNAGQVALMHQASVHEQERSGAMWT
LEWMVLPAMMTCTGAALRLATRQVQAITRIGEPPTTR
>Mature_357_residues
MNPLTSSNPYFAGLFADQEITALFEGAATADAFLAYEMALTRAAAEVGQIDIGLAQRALAAMVDFTPDVAELQSDLSADG
MAVPGYVRQLKAHVGAECVAAVHPGATSQDLIDTAQALALRAANEIYISRLTTLIDALRDLEETHGDNRLMGRTRMQAAL
PISAGHRISSWISPLVRHTSRLEILRPEVEALQFGGPVGDGQRSQPHAAAMADHMGKALGLRAPERCWHTERDSLVTYAG
WLSALTGSLGKFGQDVCLMVQQGVDALAQAGGGSSSAMAHKQNPVTAEMLVTLSRYNAGQVALMHQASVHEQERSGAMWT
LEWMVLPAMMTCTGAALRLATRQVQAITRIGEPPTTR

Specific function: Catalyzes an anti cycloisomerization [H]

COG id: COG0015

COG function: function code F; Adenylosuccinate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II fumarase/aspartase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019468
- InterPro:   IPR003031
- InterPro:   IPR000362
- InterPro:   IPR020557
- InterPro:   IPR008948
- InterPro:   IPR022761
- InterPro:   IPR012789 [H]

Pfam domain/function: PF10397 ADSL_C; PF00206 Lyase_1 [H]

EC number: =5.5.1.2 [H]

Molecular weight: Translated: 38140; Mature: 38140

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPLTSSNPYFAGLFADQEITALFEGAATADAFLAYEMALTRAAAEVGQIDIGLAQRALA
CCCCCCCCCEEEEEECCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AMVDFTPDVAELQSDLSADGMAVPGYVRQLKAHVGAECVAAVHPGATSQDLIDTAQALAL
HHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCHHHHHHCCCCCCHHHHHHHHHHHHH
RAANEIYISRLTTLIDALRDLEETHGDNRLMGRTRMQAALPISAGHRISSWISPLVRHTS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
RLEILRPEVEALQFGGPVGDGQRSQPHAAAMADHMGKALGLRAPERCWHTERDSLVTYAG
HHHHHCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHH
WLSALTGSLGKFGQDVCLMVQQGVDALAQAGGGSSSAMAHKQNPVTAEMLVTLSRYNAGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCHHHHHHHHHHCCCCC
VALMHQASVHEQERSGAMWTLEWMVLPAMMTCTGAALRLATRQVQAITRIGEPPTTR
EEEEHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNPLTSSNPYFAGLFADQEITALFEGAATADAFLAYEMALTRAAAEVGQIDIGLAQRALA
CCCCCCCCCEEEEEECCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AMVDFTPDVAELQSDLSADGMAVPGYVRQLKAHVGAECVAAVHPGATSQDLIDTAQALAL
HHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCHHHHHHCCCCCCHHHHHHHHHHHHH
RAANEIYISRLTTLIDALRDLEETHGDNRLMGRTRMQAALPISAGHRISSWISPLVRHTS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
RLEILRPEVEALQFGGPVGDGQRSQPHAAAMADHMGKALGLRAPERCWHTERDSLVTYAG
HHHHHCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHH
WLSALTGSLGKFGQDVCLMVQQGVDALAQAGGGSSSAMAHKQNPVTAEMLVTLSRYNAGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCHHHHHHHHHHCCCCC
VALMHQASVHEQERSGAMWTLEWMVLPAMMTCTGAALRLATRQVQAITRIGEPPTTR
EEEEHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8063101 [H]