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The map label for this gene is ectB [H]

Identifier: 99080393

GI number: 99080393

Start: 588982

End: 590268

Strand: Direct

Name: ectB [H]

Synonym: TM1040_0552

Alternate gene names: 99080393

Gene position: 588982-590268 (Clockwise)

Preceding gene: 99080392

Following gene: 99080394

Centisome position: 18.4

GC content: 59.98

Gene sequence:

>1287_bases
ATGCCCAAAGACATGGCAACCGATACGTCTATCTATACGCGCCGCGAAAGTAATGCGCGCTCCTACTGCCGCTCCTTCAC
AGCGTCGTTTGACACCGCACGCGGCTCCGAGCTGTTTACTGAAGACGGCACCCGCTACATCGACTTTCTGGCGGGCTGCT
CCTCGCTCAACTACGGCCACAATGACCCCGACATGAAGGATGCGCTGGTTGCGCATATCCTGAAGGACGGCATCACCCAT
GGCCTCGACTTTCATACCGAAGCCAAGGAAGCCTTCCTGCACAGCTTCACCGATTTGATCTTGGCGCCCCGTGGCATGGA
TCATAAGGTCATGTTTACCGGCCCGACGGGCGCGAACGCTGTTGAGGCAGCGATGAAGATCGCCCGCAAGGTGACCGGCC
GGACCAATGTGATTTCCTTCACCAACGGGTTTCATGGCGTGACCATGGGGGCGCTGGCCGCGACTGGTAACGGCTATCAC
CGCGGTGGGGCAGGCATGGACAAGGCGGGTGTGACCCGCATGCCGTATGATGCCTATGTCGATGGTGTCGACAGTGCAGC
GCTTCTGGACAAGATGCTGTCTGATCCGTCGGGCGGGATCGACGCGCCTGCTGCAATCATGCTGGAACCGGTGCAGGGCG
AAGGCGGTCTGAACGCCGCTTCGGCTGGTTTTGTGAAGAAAGTTCAAGAGATTGCCCATAAGCACGGCGCGCTGTTGATC
ATCGACGACATTCAGTCCGGGTGTGGTCGCACAGGCACGTTCTTCTCTTTTGAAGACATGGGCGTTCAGCCTGACGTCGT
GACCATGGCGAAATCGGTCTCGGGTTTTGGCCTGCCGATGGCGATGGTTCTGGTGCGTCCGCAGCATGACGTCTTTGGCC
CTGCCGAGCACAACGGGACCTTCCGTGGCAACACCCATGCCTTTGTGACCGCCCGTGTCGCGATCGAGAAATTCTGGGCC
GATGATGCGTTCCAGACTGAGCTTGCCCGCAAGTCGGAGCTGGTGACGAGCGCGCTGCAGGAAGTGGCAAGCCACATTCC
AGGAGCCTACCTCAAGGGTCGTGGCCTCATGCAAGGTGTCGACGTGGGCTCTGGCGAGCTGGCCGGGGACATCTGTGCCC
GTGCCTACGAGCTGGGTCTCGTGGTCGAGACCTCTGGCCCCAACGATGAGGTGGTCAAGATCCTCGCACCGCTCACCACA
TCCGAGCAGCTGCTTTGCGAAGGCTTCGCCATCCTGAGCACTGCGGCCCGCGAAGTGGCTGCAAAAACCAAAATTGCCGC
GCAATAA

Upstream 100 bases:

>100_bases
TGGTGACCATTACGCTCGACAATGAGGCAAAGATCCTCAAGCGCGCGGCCTAAACTCCTCCCCTCATCCAGAATTTACCT
TATCCGAAAAGGATTTACCC

Downstream 100 bases:

>100_bases
TCTGAAGACCGGAGACCAAGACTAATGATCGTACGCGATTTCAACGAACTGAAAAACACTGACCGCTCCGTCTCTGATGC
GCGCTGGACATCCACCCGTA

Product: diaminobutyrate--2-oxoglutarate aminotransferase

Products: NA

Alternate protein names: DABA aminotransferase; Diaminobutyrate--2-oxoglutarate aminotransferase; L-2,4-diaminobutyric acid transaminase [H]

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MPKDMATDTSIYTRRESNARSYCRSFTASFDTARGSELFTEDGTRYIDFLAGCSSLNYGHNDPDMKDALVAHILKDGITH
GLDFHTEAKEAFLHSFTDLILAPRGMDHKVMFTGPTGANAVEAAMKIARKVTGRTNVISFTNGFHGVTMGALAATGNGYH
RGGAGMDKAGVTRMPYDAYVDGVDSAALLDKMLSDPSGGIDAPAAIMLEPVQGEGGLNAASAGFVKKVQEIAHKHGALLI
IDDIQSGCGRTGTFFSFEDMGVQPDVVTMAKSVSGFGLPMAMVLVRPQHDVFGPAEHNGTFRGNTHAFVTARVAIEKFWA
DDAFQTELARKSELVTSALQEVASHIPGAYLKGRGLMQGVDVGSGELAGDICARAYELGLVVETSGPNDEVVKILAPLTT
SEQLLCEGFAILSTAAREVAAKTKIAAQ

Sequences:

>Translated_428_residues
MPKDMATDTSIYTRRESNARSYCRSFTASFDTARGSELFTEDGTRYIDFLAGCSSLNYGHNDPDMKDALVAHILKDGITH
GLDFHTEAKEAFLHSFTDLILAPRGMDHKVMFTGPTGANAVEAAMKIARKVTGRTNVISFTNGFHGVTMGALAATGNGYH
RGGAGMDKAGVTRMPYDAYVDGVDSAALLDKMLSDPSGGIDAPAAIMLEPVQGEGGLNAASAGFVKKVQEIAHKHGALLI
IDDIQSGCGRTGTFFSFEDMGVQPDVVTMAKSVSGFGLPMAMVLVRPQHDVFGPAEHNGTFRGNTHAFVTARVAIEKFWA
DDAFQTELARKSELVTSALQEVASHIPGAYLKGRGLMQGVDVGSGELAGDICARAYELGLVVETSGPNDEVVKILAPLTT
SEQLLCEGFAILSTAAREVAAKTKIAAQ
>Mature_427_residues
PKDMATDTSIYTRRESNARSYCRSFTASFDTARGSELFTEDGTRYIDFLAGCSSLNYGHNDPDMKDALVAHILKDGITHG
LDFHTEAKEAFLHSFTDLILAPRGMDHKVMFTGPTGANAVEAAMKIARKVTGRTNVISFTNGFHGVTMGALAATGNGYHR
GGAGMDKAGVTRMPYDAYVDGVDSAALLDKMLSDPSGGIDAPAAIMLEPVQGEGGLNAASAGFVKKVQEIAHKHGALLII
DDIQSGCGRTGTFFSFEDMGVQPDVVTMAKSVSGFGLPMAMVLVRPQHDVFGPAEHNGTFRGNTHAFVTARVAIEKFWAD
DAFQTELARKSELVTSALQEVASHIPGAYLKGRGLMQGVDVGSGELAGDICARAYELGLVVETSGPNDEVVKILAPLTTS
EQLLCEGFAILSTAAREVAAKTKIAAQ

Specific function: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate [H]

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=427, Percent_Identity=26.6978922716628, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI13994255, Length=365, Percent_Identity=26.3013698630137, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI284507298, Length=311, Percent_Identity=27.3311897106109, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI37574042, Length=414, Percent_Identity=25.6038647342995, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI226442705, Length=415, Percent_Identity=25.5421686746988, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI226442709, Length=319, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI188536080, Length=299, Percent_Identity=26.4214046822742, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI38679950, Length=299, Percent_Identity=26.4214046822742, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI38679946, Length=299, Percent_Identity=26.4214046822742, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1789016, Length=401, Percent_Identity=32.9177057356608, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1787560, Length=408, Percent_Identity=32.843137254902, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI1788044, Length=404, Percent_Identity=28.7128712871287, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI145693181, Length=402, Percent_Identity=25.8706467661692, Blast_Score=131, Evalue=7e-32,
Organism=Escherichia coli, GI1789759, Length=395, Percent_Identity=27.0886075949367, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI1786991, Length=299, Percent_Identity=27.7591973244147, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1786349, Length=341, Percent_Identity=26.6862170087977, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32564660, Length=409, Percent_Identity=27.8728606356968, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI25144271, Length=406, Percent_Identity=24.6305418719212, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI25144274, Length=268, Percent_Identity=26.4925373134328, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI71992977, Length=452, Percent_Identity=23.4513274336283, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17541228, Length=436, Percent_Identity=23.394495412844, Blast_Score=76, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6323470, Length=434, Percent_Identity=26.9585253456221, Blast_Score=137, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6324432, Length=417, Percent_Identity=26.6187050359712, Blast_Score=137, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6321456, Length=391, Percent_Identity=24.2966751918159, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI21357415, Length=415, Percent_Identity=26.9879518072289, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI28574759, Length=410, Percent_Identity=25.609756097561, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI161085790, Length=407, Percent_Identity=25.7985257985258, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI21356575, Length=426, Percent_Identity=24.1784037558685, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI281366494, Length=290, Percent_Identity=27.2413793103448, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24667139, Length=290, Percent_Identity=27.2413793103448, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24667143, Length=290, Percent_Identity=27.2413793103448, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR004637
- InterPro:   IPR012773
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.76 [H]

Molecular weight: Translated: 45392; Mature: 45261

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS00599 AA_TRANSFER_CLASS_2 ; PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKDMATDTSIYTRRESNARSYCRSFTASFDTARGSELFTEDGTRYIDFLAGCSSLNYGH
CCCCCCCCCHHEEECCCHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHCCCCCCC
NDPDMKDALVAHILKDGITHGLDFHTEAKEAFLHSFTDLILAPRGMDHKVMFTGPTGANA
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHH
VEAAMKIARKVTGRTNVISFTNGFHGVTMGALAATGNGYHRGGAGMDKAGVTRMPYDAYV
HHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHEECCCCCCCCCCCCCCCCCCCCCHHHHH
DGVDSAALLDKMLSDPSGGIDAPAAIMLEPVQGEGGLNAASAGFVKKVQEIAHKHGALLI
CCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEE
IDDIQSGCGRTGTFFSFEDMGVQPDVVTMAKSVSGFGLPMAMVLVRPQHDVFGPAEHNGT
EECCCCCCCCCCCEEEECCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCC
FRGNTHAFVTARVAIEKFWADDAFQTELARKSELVTSALQEVASHIPGAYLKGRGLMQGV
CCCCCEEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCC
DVGSGELAGDICARAYELGLVVETSGPNDEVVKILAPLTTSEQLLCEGFAILSTAAREVA
CCCCCHHHHHHHHHHHHEEEEEECCCCCHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHH
AKTKIAAQ
HHHHHCCC
>Mature Secondary Structure 
PKDMATDTSIYTRRESNARSYCRSFTASFDTARGSELFTEDGTRYIDFLAGCSSLNYGH
CCCCCCCCHHEEECCCHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHCCCCCCC
NDPDMKDALVAHILKDGITHGLDFHTEAKEAFLHSFTDLILAPRGMDHKVMFTGPTGANA
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHH
VEAAMKIARKVTGRTNVISFTNGFHGVTMGALAATGNGYHRGGAGMDKAGVTRMPYDAYV
HHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHEECCCCCCCCCCCCCCCCCCCCCHHHHH
DGVDSAALLDKMLSDPSGGIDAPAAIMLEPVQGEGGLNAASAGFVKKVQEIAHKHGALLI
CCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEE
IDDIQSGCGRTGTFFSFEDMGVQPDVVTMAKSVSGFGLPMAMVLVRPQHDVFGPAEHNGT
EECCCCCCCCCCCEEEECCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCC
FRGNTHAFVTARVAIEKFWADDAFQTELARKSELVTSALQEVASHIPGAYLKGRGLMQGV
CCCCCEEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCC
DVGSGELAGDICARAYELGLVVETSGPNDEVVKILAPLTTSEQLLCEGFAILSTAAREVA
CCCCCHHHHHHHHHHHHEEEEEECCCCCHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHH
AKTKIAAQ
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]