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The map label for this gene is cobP [H]

Identifier: 99080296

GI number: 99080296

Start: 472629

End: 473249

Strand: Reverse

Name: cobP [H]

Synonym: TM1040_0455

Alternate gene names: 99080296

Gene position: 473249-472629 (Counterclockwise)

Preceding gene: 99080307

Following gene: 99080295

Centisome position: 14.78

GC content: 57.49

Gene sequence:

>621_bases
ATGCTCTATGCATCCTGGTCGCCGGCGAAACTACGGATCATTCGGGCGTGGGCGTCTTGGCGCATGATGCTCAACGCGCC
TACAACTCTGAGGATACGCAAATTGGCCAGCAAAGTCACAATCATTCTCGGCGGCGCAGCGTCGGGCAAATCTGCGTTTG
CTGAGCAAGCTTGTGTTAAGACAGGGAAAAGCAGGGTTTACTGGGCGACTTCACAAATATTTGACTCTGAAATGCAGGAG
AAGGTCGCCCGCCATGTCGATCAGCGTGGCGCCGGCTGGACCACAATCGAAGAGCCCTATGAAGCCAAAACGGCGCTTGG
CGCCGCTCAATCTCAGGATGTTCTCTTGATGGATTGTGCGACCATGTGGCTCACCAACCATCTGCTTGCGGAAAATGACC
TCGAGAAAGAGACCCGCGTCCTGCTGGAGGCGATCAAGGACTGCCCCGCCGAAGTTGTCATCGTCACCAACGAGACCGGT
CTTGGGATTGTTCCCGAGAATGCGCTGGCACGGCGGTTTCGCGAGGCGCAGGGACGCTTGAATATTGCGCTCGCCGCTGC
GGCGGACACGGTGGTCTTGGTCGCAGCAGGGCTGCCAATGACGCTGAAAGGCACGACATGA

Upstream 100 bases:

>100_bases
TCTCGTCCAGTGCCATTTTAAACTCCCTGTTCTAAGAACTACGTTGACAACGTGCGAGGGCCGGCTTTGGTTCAAAAATA
ATCTGTCGGATATTCAAAAG

Downstream 100 bases:

>100_bases
TCACGCGTTTTCACATGATACGCCATGGCCCGACCCACGCCAAATCCATGGTGGGCTGGTCGGATTTACCCGCAGACCTC
TCGGATGCGGCGATGCTGTC

Product: adenosylcobinamide kinase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MLYASWSPAKLRIIRAWASWRMMLNAPTTLRIRKLASKVTIILGGAASGKSAFAEQACVKTGKSRVYWATSQIFDSEMQE
KVARHVDQRGAGWTTIEEPYEAKTALGAAQSQDVLLMDCATMWLTNHLLAENDLEKETRVLLEAIKDCPAEVVIVTNETG
LGIVPENALARRFREAQGRLNIALAAAADTVVLVAAGLPMTLKGTT

Sequences:

>Translated_206_residues
MLYASWSPAKLRIIRAWASWRMMLNAPTTLRIRKLASKVTIILGGAASGKSAFAEQACVKTGKSRVYWATSQIFDSEMQE
KVARHVDQRGAGWTTIEEPYEAKTALGAAQSQDVLLMDCATMWLTNHLLAENDLEKETRVLLEAIKDCPAEVVIVTNETG
LGIVPENALARRFREAQGRLNIALAAAADTVVLVAAGLPMTLKGTT
>Mature_206_residues
MLYASWSPAKLRIIRAWASWRMMLNAPTTLRIRKLASKVTIILGGAASGKSAFAEQACVKTGKSRVYWATSQIFDSEMQE
KVARHVDQRGAGWTTIEEPYEAKTALGAAQSQDVLLMDCATMWLTNHLLAENDLEKETRVLLEAIKDCPAEVVIVTNETG
LGIVPENALARRFREAQGRLNIALAAAADTVVLVAAGLPMTLKGTT

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=179, Percent_Identity=38.5474860335196, Blast_Score=111, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 22457; Mature: 22457

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYASWSPAKLRIIRAWASWRMMLNAPTTLRIRKLASKVTIILGGAASGKSAFAEQACVK
CCCCCCCCHHEEEEEEHHHHEEEECCCCHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHH
TGKSRVYWATSQIFDSEMQEKVARHVDQRGAGWTTIEEPYEAKTALGAAQSQDVLLMDCA
CCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCEEEHHHH
TMWLTNHLLAENDLEKETRVLLEAIKDCPAEVVIVTNETGLGIVPENALARRFREAQGRL
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCE
NIALAAAADTVVLVAAGLPMTLKGTT
EEEEEECCCEEEEEECCCCEEEECCC
>Mature Secondary Structure
MLYASWSPAKLRIIRAWASWRMMLNAPTTLRIRKLASKVTIILGGAASGKSAFAEQACVK
CCCCCCCCHHEEEEEEHHHHEEEECCCCHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHH
TGKSRVYWATSQIFDSEMQEKVARHVDQRGAGWTTIEEPYEAKTALGAAQSQDVLLMDCA
CCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCEEEHHHH
TMWLTNHLLAENDLEKETRVLLEAIKDCPAEVVIVTNETGLGIVPENALARRFREAQGRL
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCE
NIALAAAADTVVLVAAGLPMTLKGTT
EEEEEECCCEEEEEECCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1655696 [H]