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The map label for this gene is maoC [H]

Identifier: 99080278

GI number: 99080278

Start: 453126

End: 455156

Strand: Reverse

Name: maoC [H]

Synonym: TM1040_0437

Alternate gene names: 99080278

Gene position: 455156-453126 (Counterclockwise)

Preceding gene: 99080284

Following gene: 99080277

Centisome position: 14.22

GC content: 63.02

Gene sequence:

>2031_bases
ATGTGCCCGAAAGATGTGGCGAGCTTTGCCGCCGGAGAATGGATCGCACCGGACCACAGCGCACGCGAGATTGCCTCTGC
CATCACCGGAGAGGTGATTGCGCGCGCGGGCAATGCCACGCTCGATGTGCAAGCGATGCTCGATCATGCCCGCGATACGG
GCGGCCCCGCCCTGCGCGCCATGACCTTCCATGACCGCGCCCGCATGCTCAAGGCGCTGGCGCAGCATTTGGACGCCCAC
AAACAAGAGCTCTACGACCAGAGCTTTGACACCGGCGCGACCCAGAAGGACCACCTGATCGACGTGGACGGCGGCATCGG
CACGGTGTTTGTCTTTGCCTCCAAGGGGCGACGCGAAATGCCCGACAGCACGGTCTATACAGACGGCGCGGTCGAGCAAC
TGTCGCGCCACGGCAGCTTTATGGGCCAGCACATCTGCACCTCGCTGCCCGGTGTTGCGGTACATATCAACGCCTTCAAC
TTCCCGGTCTGGGGCATGCTGGAAAAGCTCGCACCCACCCTGCTCGCCGGTGTTCCGGCCATTGTAAAACCAGCCACCGC
CACCTGCTACGTCACCGAGGCCGCCGTGCGCCTAATGCTCGACAGCGGTCTTCTGCCCGAAGGGGCGTTGCAACTGGTAA
GTGGCGGACTTGGCGACATGCTGGACCGGCTGACCTGTCAGGACGTGGTGAGCTTTACCGGCTCTGCCGCAACCGCGCTC
AAACTGCGCCAGACCCCCGCGATTGTTGAAAACTCCGTGCGGTTTGTAGCGGAACAAGACAGCCTCAACGCGTCGATCCT
CGGCCCCGACGCAGCACCCGGTAGCGCGGAGTTTGATCTCTTCCTCAAGGAAGTACAGCGTGAGATGACCACCAAAGCGG
GTCAGAAGTGTACTGCGATCCGCCGCATCATCGTGCCCGACGCACAGGTAAACGCTGTGATCGATGGGCTGAGCGCCGCG
CTTGCCAAGATCACCATTGGTGACCCACGCGCCGACAGCACCCGTATGGGCGCGCTGGTCTCCGCCGCGCAAAAACGCGA
TGTGCTGGAGCAAGCCGACAAAATCGCAACCGAGGCCACCCGCGTCTTTGGCGACCCCGACAATTTCACCGTTGAGGGCG
CTGACAAAGACAAAGGCGCCTTCGTGCCGCCCATGCTGTTCCACTGTGCCGACCCGGACGCCGCGCGACATGTGCACGAC
ACCGAAGCCTTTGGCCCTGTCTCTACCGTCATGGGCTATCGCGACCTTTCTCATGCGTCCGAACTCGCCAATCGCGGCCA
AGGCTCCCTCGTGGCGTCCCTGATCACCGCAGACCCGGTGGTCGCACGCGAGGTCACGCTAAACATCGCGGCCTTCCATG
GACGCGTCTATATCAACAATGCCACCTCCATGAAGGAATCCACGGGCCACGGCTCTCCCCTGCCCCATATGGTGCATGGC
GGCCCCGGTCGCGCCGGCGGCGGCGAGGAGCTGGGCGGCGTGCGTGCGGTGAAACACTACATGCAGCGCACTGCGGTACA
GGGTTCGCCCGAGATTCTGTCGGCGATCACCGGCAAATGGGTGCCCGGCGGCCCCGAAACCACAGGGCCCGCACATCCCT
TCACGCGCCGCTTTGGCGCACTCACGATTGGGGAAACACTGCACACCGCGCCGCGTGTCGTCACCAGCGATGACGTCGCC
CATTTTGCGCAGTTCACCGGCGACACCTTCTATGCCCACATGGACGATGCCGCCGCAGAGCGAAACCCGTTCTTTCCCGG
CCGCGTTGCTCATGGCTACCTGCTCCTGTCCTTTGCAGCGGGCATGTTCGTAGAGCCGAATGAGGGCCCCGTGCTCGCCA
ATACCGGACTTGATAACCTGCGCTTCATGAAGCCGGTGGTGCCTGGCGACAGCATCAAGGTGCGCCTGACCGTCAAAGCC
AAGACCCCGCGAAACGAAGAATATGGCGAGGTCCGCTGGCATGTGACCCTCACCAATCAAGATGATGAGCTGGTGGCGGA
ATACGACCTGCTGACCATGGTGGCGTTCTGA

Upstream 100 bases:

>100_bases
ACCGACCGGACGGTCAATATATTCAATCAGGAAAATGAGCCGCCCCGAACTCGGGCGCTGGCACTGCATTTGCACAACAG
GCTTCAGGGAGACACGAGAC

Downstream 100 bases:

>100_bases
ACCCACCTCAGCCTCGATGATGTCACGTCATGGCAGTTGGGCTGGCGCTAACCCGCGCCAGCCCTTATCGTATCTGCATG
ACACAACACACCGACGACTG

Product: bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase

Products: NA

Alternate protein names: Phenylacetic acid degradation protein paaZ [H]

Number of amino acids: Translated: 676; Mature: 676

Protein sequence:

>676_residues
MCPKDVASFAAGEWIAPDHSAREIASAITGEVIARAGNATLDVQAMLDHARDTGGPALRAMTFHDRARMLKALAQHLDAH
KQELYDQSFDTGATQKDHLIDVDGGIGTVFVFASKGRREMPDSTVYTDGAVEQLSRHGSFMGQHICTSLPGVAVHINAFN
FPVWGMLEKLAPTLLAGVPAIVKPATATCYVTEAAVRLMLDSGLLPEGALQLVSGGLGDMLDRLTCQDVVSFTGSAATAL
KLRQTPAIVENSVRFVAEQDSLNASILGPDAAPGSAEFDLFLKEVQREMTTKAGQKCTAIRRIIVPDAQVNAVIDGLSAA
LAKITIGDPRADSTRMGALVSAAQKRDVLEQADKIATEATRVFGDPDNFTVEGADKDKGAFVPPMLFHCADPDAARHVHD
TEAFGPVSTVMGYRDLSHASELANRGQGSLVASLITADPVVAREVTLNIAAFHGRVYINNATSMKESTGHGSPLPHMVHG
GPGRAGGGEELGGVRAVKHYMQRTAVQGSPEILSAITGKWVPGGPETTGPAHPFTRRFGALTIGETLHTAPRVVTSDDVA
HFAQFTGDTFYAHMDDAAAERNPFFPGRVAHGYLLLSFAAGMFVEPNEGPVLANTGLDNLRFMKPVVPGDSIKVRLTVKA
KTPRNEEYGEVRWHVTLTNQDDELVAEYDLLTMVAF

Sequences:

>Translated_676_residues
MCPKDVASFAAGEWIAPDHSAREIASAITGEVIARAGNATLDVQAMLDHARDTGGPALRAMTFHDRARMLKALAQHLDAH
KQELYDQSFDTGATQKDHLIDVDGGIGTVFVFASKGRREMPDSTVYTDGAVEQLSRHGSFMGQHICTSLPGVAVHINAFN
FPVWGMLEKLAPTLLAGVPAIVKPATATCYVTEAAVRLMLDSGLLPEGALQLVSGGLGDMLDRLTCQDVVSFTGSAATAL
KLRQTPAIVENSVRFVAEQDSLNASILGPDAAPGSAEFDLFLKEVQREMTTKAGQKCTAIRRIIVPDAQVNAVIDGLSAA
LAKITIGDPRADSTRMGALVSAAQKRDVLEQADKIATEATRVFGDPDNFTVEGADKDKGAFVPPMLFHCADPDAARHVHD
TEAFGPVSTVMGYRDLSHASELANRGQGSLVASLITADPVVAREVTLNIAAFHGRVYINNATSMKESTGHGSPLPHMVHG
GPGRAGGGEELGGVRAVKHYMQRTAVQGSPEILSAITGKWVPGGPETTGPAHPFTRRFGALTIGETLHTAPRVVTSDDVA
HFAQFTGDTFYAHMDDAAAERNPFFPGRVAHGYLLLSFAAGMFVEPNEGPVLANTGLDNLRFMKPVVPGDSIKVRLTVKA
KTPRNEEYGEVRWHVTLTNQDDELVAEYDLLTMVAF
>Mature_676_residues
MCPKDVASFAAGEWIAPDHSAREIASAITGEVIARAGNATLDVQAMLDHARDTGGPALRAMTFHDRARMLKALAQHLDAH
KQELYDQSFDTGATQKDHLIDVDGGIGTVFVFASKGRREMPDSTVYTDGAVEQLSRHGSFMGQHICTSLPGVAVHINAFN
FPVWGMLEKLAPTLLAGVPAIVKPATATCYVTEAAVRLMLDSGLLPEGALQLVSGGLGDMLDRLTCQDVVSFTGSAATAL
KLRQTPAIVENSVRFVAEQDSLNASILGPDAAPGSAEFDLFLKEVQREMTTKAGQKCTAIRRIIVPDAQVNAVIDGLSAA
LAKITIGDPRADSTRMGALVSAAQKRDVLEQADKIATEATRVFGDPDNFTVEGADKDKGAFVPPMLFHCADPDAARHVHD
TEAFGPVSTVMGYRDLSHASELANRGQGSLVASLITADPVVAREVTLNIAAFHGRVYINNATSMKESTGHGSPLPHMVHG
GPGRAGGGEELGGVRAVKHYMQRTAVQGSPEILSAITGKWVPGGPETTGPAHPFTRRFGALTIGETLHTAPRVVTSDDVA
HFAQFTGDTFYAHMDDAAAERNPFFPGRVAHGYLLLSFAAGMFVEPNEGPVLANTGLDNLRFMKPVVPGDSIKVRLTVKA
KTPRNEEYGEVRWHVTLTNQDDELVAEYDLLTMVAF

Specific function: Phenylacetic acid aerobic catabolism. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI153266822, Length=443, Percent_Identity=24.8306997742664, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI25777724, Length=497, Percent_Identity=24.3460764587525, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI12007648, Length=424, Percent_Identity=25, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI25777728, Length=440, Percent_Identity=24.3181818181818, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI25777730, Length=478, Percent_Identity=24.6861924686192, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI21361176, Length=443, Percent_Identity=24.1534988713318, Blast_Score=83, Evalue=8e-16,
Organism=Homo sapiens, GI25777732, Length=477, Percent_Identity=24.7379454926625, Blast_Score=80, Evalue=8e-15,
Organism=Homo sapiens, GI115387104, Length=363, Percent_Identity=26.4462809917355, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI238814322, Length=453, Percent_Identity=23.6203090507726, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI188035924, Length=357, Percent_Identity=25.7703081232493, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI310128103, Length=357, Percent_Identity=25.7703081232493, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI1787653, Length=679, Percent_Identity=52.1354933726068, Blast_Score=640, Evalue=0.0,
Organism=Escherichia coli, GI87082295, Length=507, Percent_Identity=26.0355029585799, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1789015, Length=484, Percent_Identity=24.5867768595041, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1787684, Length=346, Percent_Identity=27.1676300578035, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI87081896, Length=359, Percent_Identity=26.4623955431755, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1786504, Length=460, Percent_Identity=26.5217391304348, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI87081926, Length=343, Percent_Identity=22.7405247813411, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787558, Length=406, Percent_Identity=26.8472906403941, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787715, Length=344, Percent_Identity=27.3255813953488, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788042, Length=442, Percent_Identity=25.5656108597285, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1787250, Length=353, Percent_Identity=25.2124645892351, Blast_Score=77, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI25143874, Length=512, Percent_Identity=25.5859375, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI25143876, Length=512, Percent_Identity=25.5859375, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17562198, Length=480, Percent_Identity=23.75, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115532534, Length=371, Percent_Identity=25.6064690026954, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI133930964, Length=459, Percent_Identity=22.8758169934641, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17534447, Length=359, Percent_Identity=25.6267409470752, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI32564151, Length=277, Percent_Identity=27.0758122743682, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71986308, Length=443, Percent_Identity=23.9277652370203, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320917, Length=362, Percent_Identity=27.0718232044199, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6324950, Length=449, Percent_Identity=25.1670378619154, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6323822, Length=363, Percent_Identity=25.8953168044077, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6325196, Length=436, Percent_Identity=23.8532110091743, Blast_Score=74, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6323821, Length=367, Percent_Identity=25.0681198910082, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI20129399, Length=526, Percent_Identity=25.6653992395437, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI281362580, Length=430, Percent_Identity=25.5813953488372, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI62472918, Length=430, Percent_Identity=25.5813953488372, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI62472926, Length=430, Percent_Identity=25.5813953488372, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI62472936, Length=430, Percent_Identity=25.5813953488372, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21356737, Length=430, Percent_Identity=25.5813953488372, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24650465, Length=446, Percent_Identity=23.7668161434978, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR002539
- InterPro:   IPR011966 [H]

Pfam domain/function: PF00171 Aldedh; PF01575 MaoC_dehydratas [H]

EC number: NA

Molecular weight: Translated: 72098; Mature: 72098

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCPKDVASFAAGEWIAPDHSAREIASAITGEVIARAGNATLDVQAMLDHARDTGGPALRA
CCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCEEEE
MTFHDRARMLKALAQHLDAHKQELYDQSFDTGATQKDHLIDVDGGIGTVFVFASKGRREM
EHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEEEEEECCCCCCC
PDSTVYTDGAVEQLSRHGSFMGQHICTSLPGVAVHINAFNFPVWGMLEKLAPTLLAGVPA
CCCCEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCH
IVKPATATCYVTEAAVRLMLDSGLLPEGALQLVSGGLGDMLDRLTCQDVVSFTGSAATAL
HHCCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHEE
KLRQTPAIVENSVRFVAEQDSLNASILGPDAAPGSAEFDLFLKEVQREMTTKAGQKCTAI
EECCCCHHHHCCHHEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHH
RRIIVPDAQVNAVIDGLSAALAKITIGDPRADSTRMGALVSAAQKRDVLEQADKIATEAT
HHHHCCCCHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVFGDPDNFTVEGADKDKGAFVPPMLFHCADPDAARHVHDTEAFGPVSTVMGYRDLSHAS
HHCCCCCCEEEECCCCCCCCCCCCHHEECCCCHHHHHCCCCHHCCCHHHHHHHHHHHHHH
ELANRGQGSLVASLITADPVVAREVTLNIAAFHGRVYINNATSMKESTGHGSPLPHMVHG
HHHHCCCCHHHHHHHHCCCCEEHEEEEEEEEEECEEEECCCCCCCCCCCCCCCCCCCCCC
GPGRAGGGEELGGVRAVKHYMQRTAVQGSPEILSAITGKWVPGGPETTGPAHPFTRRFGA
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCC
LTIGETLHTAPRVVTSDDVAHFAQFTGDTFYAHMDDAAAERNPFFPGRVAHGYLLLSFAA
EEECHHHHCCCCEECCHHHHHHHHHCCCEEEEECCCHHHCCCCCCCCHHHHHHHHHHHHC
GMFVEPNEGPVLANTGLDNLRFMKPVVPGDSIKVRLTVKAKTPRNEEYGEVRWHVTLTNQ
CCEECCCCCCEEEECCCCCCHHHCCCCCCCCEEEEEEEEECCCCCCCCCEEEEEEEEECC
DDELVAEYDLLTMVAF
CCHHHHHHHHHHHHCC
>Mature Secondary Structure
MCPKDVASFAAGEWIAPDHSAREIASAITGEVIARAGNATLDVQAMLDHARDTGGPALRA
CCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCEEEE
MTFHDRARMLKALAQHLDAHKQELYDQSFDTGATQKDHLIDVDGGIGTVFVFASKGRREM
EHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEEEEEECCCCCCC
PDSTVYTDGAVEQLSRHGSFMGQHICTSLPGVAVHINAFNFPVWGMLEKLAPTLLAGVPA
CCCCEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCH
IVKPATATCYVTEAAVRLMLDSGLLPEGALQLVSGGLGDMLDRLTCQDVVSFTGSAATAL
HHCCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHEE
KLRQTPAIVENSVRFVAEQDSLNASILGPDAAPGSAEFDLFLKEVQREMTTKAGQKCTAI
EECCCCHHHHCCHHEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHH
RRIIVPDAQVNAVIDGLSAALAKITIGDPRADSTRMGALVSAAQKRDVLEQADKIATEAT
HHHHCCCCHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVFGDPDNFTVEGADKDKGAFVPPMLFHCADPDAARHVHDTEAFGPVSTVMGYRDLSHAS
HHCCCCCCEEEECCCCCCCCCCCCHHEECCCCHHHHHCCCCHHCCCHHHHHHHHHHHHHH
ELANRGQGSLVASLITADPVVAREVTLNIAAFHGRVYINNATSMKESTGHGSPLPHMVHG
HHHHCCCCHHHHHHHHCCCCEEHEEEEEEEEEECEEEECCCCCCCCCCCCCCCCCCCCCC
GPGRAGGGEELGGVRAVKHYMQRTAVQGSPEILSAITGKWVPGGPETTGPAHPFTRRFGA
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCC
LTIGETLHTAPRVVTSDDVAHFAQFTGDTFYAHMDDAAAERNPFFPGRVAHGYLLLSFAA
EEECHHHHCCCCEECCHHHHHHHHHCCCEEEEECCCHHHCCCCCCCCHHHHHHHHHHHHC
GMFVEPNEGPVLANTGLDNLRFMKPVVPGDSIKVRLTVKAKTPRNEEYGEVRWHVTLTNQ
CCEECCCCCCEEEECCCCCCHHHCCCCCCCCEEEEEEEEECCCCCCCCCEEEEEEEEECC
DDELVAEYDLLTMVAF
CCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]