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The map label for this gene is sigK [H]

Identifier: 99080256

GI number: 99080256

Start: 425629

End: 426225

Strand: Direct

Name: sigK [H]

Synonym: TM1040_0415

Alternate gene names: 99080256

Gene position: 425629-426225 (Clockwise)

Preceding gene: 99080246

Following gene: 99080257

Centisome position: 13.3

GC content: 62.31

Gene sequence:

>597_bases
GTGGGCGAGGGCACAAGCGGTTGCCGGGAGAGCGACAGAGTGACAGGTGAGGCATATTCCGAGACGACAGTCTGGATGCT
GGCAGTGCGCGATGACAGGGACAAAGCCGCCTTCGGGCGCTTGTTCGATCACTTTGCGCCCCGCCTCAAAGGCGTGATTT
GCCGCTCGGGTGTCTCCCCTGCGCAGGCTGAGGACATCGTTCAGGACGTGATGCTCACGGTCTGGCGAAAGTCGCATATG
TTCGACCCCGGTCGCGCTCAGGTTTCGGCCTGGATCTACCAGATCGCGCGCAACCGGCAGATCGACATCTTGCGCAAGGA
AAAGCGTCCCGTACCGGAAGAGTTGAAGCCGGTCGAGGACACAGAGGATGACGCGTCACAGGTCGTGGCGCTGGAACAGG
AGACGCAGGCTCTGCGTGCGGCGCTTCAGACCCTGAAGCCCGCGCAGCGCGAAATGGTGGAGCGCGCCTATCTGGGCGAG
CTGACCCATGCGGAGATCAAGGCCGAGACCGGTCTGCCGCTGGGAACCATCAAGTCGCGCATCCGGCTGGGGCTGGAGAA
ACTGCGTCATGAATTGAAGGGAACGCAACGCTCATGA

Upstream 100 bases:

>100_bases
TTATGATCTGCTCGATGAAGCCGTGCGTACTGAAGGTATGTTCGAAGCATCTGCAGCTCTTTGTGAGGACCCACTTGATG
CCCGCGCCCCGACCGCTAGT

Downstream 100 bases:

>100_bases
CGGGTATTACGCACCATATCCCTGACGAGTTGCTGATAGCCTACGCGGCGGGCAGCTTGACAAAGGCGTTTTCACTTGTG
GTCGCCGCGCATGTTTCCAT

Product: RNA polymerase sigma factor RpoE

Products: NA

Alternate protein names: Sigma-K factor [H]

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MGEGTSGCRESDRVTGEAYSETTVWMLAVRDDRDKAAFGRLFDHFAPRLKGVICRSGVSPAQAEDIVQDVMLTVWRKSHM
FDPGRAQVSAWIYQIARNRQIDILRKEKRPVPEELKPVEDTEDDASQVVALEQETQALRAALQTLKPAQREMVERAYLGE
LTHAEIKAETGLPLGTIKSRIRLGLEKLRHELKGTQRS

Sequences:

>Translated_198_residues
MGEGTSGCRESDRVTGEAYSETTVWMLAVRDDRDKAAFGRLFDHFAPRLKGVICRSGVSPAQAEDIVQDVMLTVWRKSHM
FDPGRAQVSAWIYQIARNRQIDILRKEKRPVPEELKPVEDTEDDASQVVALEQETQALRAALQTLKPAQREMVERAYLGE
LTHAEIKAETGLPLGTIKSRIRLGLEKLRHELKGTQRS
>Mature_197_residues
GEGTSGCRESDRVTGEAYSETTVWMLAVRDDRDKAAFGRLFDHFAPRLKGVICRSGVSPAQAEDIVQDVMLTVWRKSHMF
DPGRAQVSAWIYQIARNRQIDILRKEKRPVPEELKPVEDTEDDASQVVALEQETQALRAALQTLKPAQREMVERAYLGEL
THAEIKAETGLPLGTIKSRIRLGLEKLRHELKGTQRS

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR007627
- InterPro:   IPR007630
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF04545 Sigma70_r4 [H]

EC number: NA

Molecular weight: Translated: 22354; Mature: 22223

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS01063 SIGMA70_ECF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEGTSGCRESDRVTGEAYSETTVWMLAVRDDRDKAAFGRLFDHFAPRLKGVICRSGVSP
CCCCCCCCCHHCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCH
AQAEDIVQDVMLTVWRKSHMFDPGRAQVSAWIYQIARNRQIDILRKEKRPVPEELKPVED
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHCCCCCC
TEDDASQVVALEQETQALRAALQTLKPAQREMVERAYLGELTHAEIKAETGLPLGTIKSR
CCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHH
IRLGLEKLRHELKGTQRS
HHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GEGTSGCRESDRVTGEAYSETTVWMLAVRDDRDKAAFGRLFDHFAPRLKGVICRSGVSP
CCCCCCCCHHCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCH
AQAEDIVQDVMLTVWRKSHMFDPGRAQVSAWIYQIARNRQIDILRKEKRPVPEELKPVED
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHCCCCCC
TEDDASQVVALEQETQALRAALQTLKPAQREMVERAYLGELTHAEIKAETGLPLGTIKSR
CCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHH
IRLGLEKLRHELKGTQRS
HHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]