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The map label for this gene is csgA [H]

Identifier: 99080248

GI number: 99080248

Start: 418401

End: 419141

Strand: Reverse

Name: csgA [H]

Synonym: TM1040_0407

Alternate gene names: 99080248

Gene position: 419141-418401 (Counterclockwise)

Preceding gene: 99080249

Following gene: 99080247

Centisome position: 13.09

GC content: 60.46

Gene sequence:

>741_bases
ATGACAGACCCGCGCACAGTCGTGATTTTTGGAGCCTCAGGCGGCATTGGCCGCGCCCTGGTGGAAACCTATGCCGGCAT
GTCGGCGGTTGAGACGGTCCATGCCGTATCCCGCGGGGGTGACATCTCCTTTGAAGGGTCGCCCGCTGGCCAAGAGAAAA
TCGCTCAACATCAAGCAGATATAACATCCGACTCGGATCTTGAAGCACTCGCAACGCGGATCGGTGCGGCGGAGATGGTG
ATTGTGGCAACCGGCATTCTGACCGACCAAGAGACAGGGCTTTCACCGGAAAAGAGCTACCGGCATCAAGACAAAGCCGC
GTTTGAGCAGGTGTTCGGCATCAACACGATCGGCCCTGCGCTGGTGGCCAAACACTTTCTGGGGCGGATGCCCCGCAAGG
GACGCACGGTTTTTGCGGCACTGGCCGCTCGGGTGGGATCCATCAGCGACAACGGCCTCGGCGGTTGGCACGCCTATCGT
GCCTCCAAGGCTGCATTGTGTATGCTGATGCGCAACTACGCCATCGAGGTTGCACGCAAGAACGAAGATGCGATCTGCGT
CTGCCTGCACCCCGGCACCGTGGACACGGGGCTTTCCGCCCCGTTTCAGGGCAATGTTCCCGAGGGCAAACTGTTCACGC
CTGAATACTCTGCGAAATGCCTGGCCTCCGTGCTGAGCCAGCTGACCCCCAAAGACAGCGGCAAACAGTTCGACTGGGCG
GGTGCGGAGGTACCAGCCTAA

Upstream 100 bases:

>100_bases
CGATGCGCTCAAATCGGTTCCAGACTTCTTTTCCCGCGCCGTTTTCGTGGGTGTTTCGCATCGCTGCACTCCTGCCCCGC
AAATTGGTAACGAGGTTGAT

Downstream 100 bases:

>100_bases
TCCAAATCCCTCAGCGCCCGCCTTGCACCCAAGGCGCGTTCCAGCGAGACTGTTCGCACATGGAGCGCCGTCTGGCGGCG
CTGGGAGGGAGCCCCATTCA

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: C signal [H]

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MTDPRTVVIFGASGGIGRALVETYAGMSAVETVHAVSRGGDISFEGSPAGQEKIAQHQADITSDSDLEALATRIGAAEMV
IVATGILTDQETGLSPEKSYRHQDKAAFEQVFGINTIGPALVAKHFLGRMPRKGRTVFAALAARVGSISDNGLGGWHAYR
ASKAALCMLMRNYAIEVARKNEDAICVCLHPGTVDTGLSAPFQGNVPEGKLFTPEYSAKCLASVLSQLTPKDSGKQFDWA
GAEVPA

Sequences:

>Translated_246_residues
MTDPRTVVIFGASGGIGRALVETYAGMSAVETVHAVSRGGDISFEGSPAGQEKIAQHQADITSDSDLEALATRIGAAEMV
IVATGILTDQETGLSPEKSYRHQDKAAFEQVFGINTIGPALVAKHFLGRMPRKGRTVFAALAARVGSISDNGLGGWHAYR
ASKAALCMLMRNYAIEVARKNEDAICVCLHPGTVDTGLSAPFQGNVPEGKLFTPEYSAKCLASVLSQLTPKDSGKQFDWA
GAEVPA
>Mature_245_residues
TDPRTVVIFGASGGIGRALVETYAGMSAVETVHAVSRGGDISFEGSPAGQEKIAQHQADITSDSDLEALATRIGAAEMVI
VATGILTDQETGLSPEKSYRHQDKAAFEQVFGINTIGPALVAKHFLGRMPRKGRTVFAALAARVGSISDNGLGGWHAYRA
SKAALCMLMRNYAIEVARKNEDAICVCLHPGTVDTGLSAPFQGNVPEGKLFTPEYSAKCLASVLSQLTPKDSGKQFDWAG
AEVPA

Specific function: Cell-cell signaling protein required for fruiting body morphogenesis. Necessary for cellular aggregation, for spore differentiation, and for gene expression that is initiated after 6 hour of starvation [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To yeast YKL071W [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322227, Length=251, Percent_Identity=29.0836653386454, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: NA

Molecular weight: Translated: 25895; Mature: 25763

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDPRTVVIFGASGGIGRALVETYAGMSAVETVHAVSRGGDISFEGSPAGQEKIAQHQAD
CCCCCEEEEEECCCCHHHHHHHHHHCHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHC
ITSDSDLEALATRIGAAEMVIVATGILTDQETGLSPEKSYRHQDKAAFEQVFGINTIGPA
CCCCCHHHHHHHHHCHHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHH
LVAKHFLGRMPRKGRTVFAALAARVGSISDNGLGGWHAYRASKAALCMLMRNYAIEVARK
HHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEC
NEDAICVCLHPGTVDTGLSAPFQGNVPEGKLFTPEYSAKCLASVLSQLTPKDSGKQFDWA
CCCEEEEEECCCCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHCCCCCCCCCCCCC
GAEVPA
CCCCCC
>Mature Secondary Structure 
TDPRTVVIFGASGGIGRALVETYAGMSAVETVHAVSRGGDISFEGSPAGQEKIAQHQAD
CCCCEEEEEECCCCHHHHHHHHHHCHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHC
ITSDSDLEALATRIGAAEMVIVATGILTDQETGLSPEKSYRHQDKAAFEQVFGINTIGPA
CCCCCHHHHHHHHHCHHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHH
LVAKHFLGRMPRKGRTVFAALAARVGSISDNGLGGWHAYRASKAALCMLMRNYAIEVARK
HHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEC
NEDAICVCLHPGTVDTGLSAPFQGNVPEGKLFTPEYSAKCLASVLSQLTPKDSGKQFDWA
CCCEEEEEECCCCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHCCCCCCCCCCCCC
GAEVPA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2152896; 2107980; 2118510; 1372277 [H]