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The map label for this gene is cycM [H]

Identifier: 99080245

GI number: 99080245

Start: 413522

End: 414805

Strand: Direct

Name: cycM [H]

Synonym: TM1040_0404

Alternate gene names: 99080245

Gene position: 413522-414805 (Clockwise)

Preceding gene: 99080244

Following gene: 99080246

Centisome position: 12.92

GC content: 62.69

Gene sequence:

>1284_bases
ATGCTGCGGCGACTGGCTCTTGGCCTGCTCCTCTGCGCCGCCTCTGGGGTGAGCGCGGAGGAGTTCCAGACCCTCAAAGG
ACACGGAGGGCCGATCATGGCGCTTGCCGTGAACGATCGGGGGCACGTGGCCAGCGCCAGTTTCGACAATTCCGTCTCAC
TCTGGCAGGAGGGGGCGCCGAGCTGGCTCGAGGCACATGAAGCAGCCGCGACCGTGGTGGCCTTTGGCCCTGATGATACC
CTGTTCAGCGCAGGCGACGACTTTGTGATTTATCGCTGGCAGCAGGGCCACCCCCAAGAGATCGGACGGCATACCGCCAA
GATCCGCGCCTTGGACCTCTCGCGCGATGGGGAATGGCTCGCCTCCGCAAGCTGGGATGGCGGCATTGGTCTTTGGCCTA
TGAGTGCGGGCACGCCCCGCCGCATCGCGGTTGGAACGGGCGTGAACGATCTTGCCTTTGACGGGGCCGGTCGCCTCTTC
GTCGCCACCATGACCGGGCAGATCCAAGTCTTCGACAGCCCGGAGGCTGCCCCACGAATTCTGGCGGAACAAGGGTTTGG
CATCAACCGTTTGGTGCTCTCTGCTGCTGGCTGGCTGGCCTATGGCGCCGTTGATGGCGGCACCCGTGTGATCAACGCAG
AAACCGGGGCCGAGATTGCCGATTTCACCCTCGACCGGCGGCCCATACTGGCCCTTGCGCATCATGCCGAGAGCCAGCAG
ATCGCCGTGGGTGATGGGCATGGCTATATCATGATGATCGACACACACGACTGGAGCATTGCGCGCGATTTTCGGGCCAT
GCGCGAAGGCCCCGTCTGGGCTCTGGCGTTTTCAAAGGACGGCCAGCGGGTCTGGGCAGGCGGCATACACGATGTGATCT
ATGGCTGGCCCATCGCGCTGATGGCCAGCAGCCCAGCGGCGGGAACCGAGACCCGCACATTCCTGCAGGCGCCTGAAACC
ATGCCCAATGGTGAGCGCCAATTCATGCGAAAATGCTCGGTTTGCCACGATTTGGTCGCCACAGAGCAGCGGCGCGCCGG
TCCTCATCTGGCGGGGCTCTTTGGACGACCGGCCGGCAGTCTGCCTGGCTATCGGTATTCCGACACGCTGGCGCAGTCTG
ACATCATCTGGGGTGCCGAGACCATCGATGCCCTGTTCGATCTCGGCCCTGACCATTATATTCCGGGGTCCAAGATGCCG
ATGCAGCGCATCACCGCCCCCACAGATCGCCAAGATCTGATAGACTATCTGAAAACCGCGACACAACTTTCGGAGGATAA
TTGA

Upstream 100 bases:

>100_bases
GCCTGGGCCCATCAGCACCATTCGATCTGGCTCGAAGAAGTGAAGGAAAAAGAGCGCGCAAAAGGCAGCGACGCGAGCGC
CACTCCGGCGGAGTGACGCG

Downstream 100 bases:

>100_bases
AATGAAAGCCATGCTAACAGGCTTTGCCCTCATCGCCGTCATCGCCGTGGGCGCAGATCTTGCGCTGGAGCAGGCAGGGT
ATTCGGCGCAGGAGCAAAAC

Product: cytochrome c, class I

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MLRRLALGLLLCAASGVSAEEFQTLKGHGGPIMALAVNDRGHVASASFDNSVSLWQEGAPSWLEAHEAAATVVAFGPDDT
LFSAGDDFVIYRWQQGHPQEIGRHTAKIRALDLSRDGEWLASASWDGGIGLWPMSAGTPRRIAVGTGVNDLAFDGAGRLF
VATMTGQIQVFDSPEAAPRILAEQGFGINRLVLSAAGWLAYGAVDGGTRVINAETGAEIADFTLDRRPILALAHHAESQQ
IAVGDGHGYIMMIDTHDWSIARDFRAMREGPVWALAFSKDGQRVWAGGIHDVIYGWPIALMASSPAAGTETRTFLQAPET
MPNGERQFMRKCSVCHDLVATEQRRAGPHLAGLFGRPAGSLPGYRYSDTLAQSDIIWGAETIDALFDLGPDHYIPGSKMP
MQRITAPTDRQDLIDYLKTATQLSEDN

Sequences:

>Translated_427_residues
MLRRLALGLLLCAASGVSAEEFQTLKGHGGPIMALAVNDRGHVASASFDNSVSLWQEGAPSWLEAHEAAATVVAFGPDDT
LFSAGDDFVIYRWQQGHPQEIGRHTAKIRALDLSRDGEWLASASWDGGIGLWPMSAGTPRRIAVGTGVNDLAFDGAGRLF
VATMTGQIQVFDSPEAAPRILAEQGFGINRLVLSAAGWLAYGAVDGGTRVINAETGAEIADFTLDRRPILALAHHAESQQ
IAVGDGHGYIMMIDTHDWSIARDFRAMREGPVWALAFSKDGQRVWAGGIHDVIYGWPIALMASSPAAGTETRTFLQAPET
MPNGERQFMRKCSVCHDLVATEQRRAGPHLAGLFGRPAGSLPGYRYSDTLAQSDIIWGAETIDALFDLGPDHYIPGSKMP
MQRITAPTDRQDLIDYLKTATQLSEDN
>Mature_427_residues
MLRRLALGLLLCAASGVSAEEFQTLKGHGGPIMALAVNDRGHVASASFDNSVSLWQEGAPSWLEAHEAAATVVAFGPDDT
LFSAGDDFVIYRWQQGHPQEIGRHTAKIRALDLSRDGEWLASASWDGGIGLWPMSAGTPRRIAVGTGVNDLAFDGAGRLF
VATMTGQIQVFDSPEAAPRILAEQGFGINRLVLSAAGWLAYGAVDGGTRVINAETGAEIADFTLDRRPILALAHHAESQQ
IAVGDGHGYIMMIDTHDWSIARDFRAMREGPVWALAFSKDGQRVWAGGIHDVIYGWPIALMASSPAAGTETRTFLQAPET
MPNGERQFMRKCSVCHDLVATEQRRAGPHLAGLFGRPAGSLPGYRYSDTLAQSDIIWGAETIDALFDLGPDHYIPGSKMP
MQRITAPTDRQDLIDYLKTATQLSEDN

Specific function: May be involved in electron transfer from bc1 complex to aa3 [H]

COG id: COG3474

COG function: function code C; Cytochrome c2

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c family [H]

Homologues:

Organism=Homo sapiens, GI11128019, Length=98, Percent_Identity=42.8571428571429, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI26665869, Length=289, Percent_Identity=23.8754325259516, Blast_Score=69, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320796, Length=105, Percent_Identity=31.4285714285714, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322508, Length=99, Percent_Identity=34.3434343434343, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17137228, Length=99, Percent_Identity=37.3737373737374, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17137204, Length=97, Percent_Identity=34.020618556701, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002327
- InterPro:   IPR009056
- InterPro:   IPR003088 [H]

Pfam domain/function: PF00034 Cytochrom_C [H]

EC number: NA

Molecular weight: Translated: 46064; Mature: 46064

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS51007 CYTC ; PS50082 WD_REPEATS_2 ; PS50294 WD_REPEATS_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRRLALGLLLCAASGVSAEEFQTLKGHGGPIMALAVNDRGHVASASFDNSVSLWQEGAP
CHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEEEECCCCCEEECCCCCCHHHHHCCCC
SWLEAHEAAATVVAFGPDDTLFSAGDDFVIYRWQQGHPQEIGRHTAKIRALDLSRDGEWL
HHHHHHHCEEEEEEECCCCCEEECCCCEEEEEECCCCHHHHHHHHEEEEEEECCCCCCEE
ASASWDGGIGLWPMSAGTPRRIAVGTGVNDLAFDGAGRLFVATMTGQIQVFDSPEAAPRI
EECCCCCCEEEEECCCCCCCEEEEECCCCHHEECCCCCEEEEEECCEEEEECCCCHHHHH
LAEQGFGINRLVLSAAGWLAYGAVDGGTRVINAETGAEIADFTLDRRPILALAHHAESQQ
HHHCCCCHHHHHHHHCCCEEEEEECCCCEEEECCCCCCHHHHCCCCCCCEEEEECCCCCE
IAVGDGHGYIMMIDTHDWSIARDFRAMREGPVWALAFSKDGQRVWAGGIHDVIYGWPIAL
EEEECCCEEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCEEECCCHHHHHHCCCEEE
MASSPAAGTETRTFLQAPETMPNGERQFMRKCSVCHDLVATEQRRAGPHLAGLFGRPAGS
EECCCCCCCCCHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHCCCCCCC
LPGYRYSDTLAQSDIIWGAETIDALFDLGPDHYIPGSKMPMQRITAPTDRQDLIDYLKTA
CCCCCCHHHHHCCCEEECHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHH
TQLSEDN
HHHCCCC
>Mature Secondary Structure
MLRRLALGLLLCAASGVSAEEFQTLKGHGGPIMALAVNDRGHVASASFDNSVSLWQEGAP
CHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEEEECCCCCEEECCCCCCHHHHHCCCC
SWLEAHEAAATVVAFGPDDTLFSAGDDFVIYRWQQGHPQEIGRHTAKIRALDLSRDGEWL
HHHHHHHCEEEEEEECCCCCEEECCCCEEEEEECCCCHHHHHHHHEEEEEEECCCCCCEE
ASASWDGGIGLWPMSAGTPRRIAVGTGVNDLAFDGAGRLFVATMTGQIQVFDSPEAAPRI
EECCCCCCEEEEECCCCCCCEEEEECCCCHHEECCCCCEEEEEECCEEEEECCCCHHHHH
LAEQGFGINRLVLSAAGWLAYGAVDGGTRVINAETGAEIADFTLDRRPILALAHHAESQQ
HHHCCCCHHHHHHHHCCCEEEEEECCCCEEEECCCCCCHHHHCCCCCCCEEEEECCCCCE
IAVGDGHGYIMMIDTHDWSIARDFRAMREGPVWALAFSKDGQRVWAGGIHDVIYGWPIAL
EEEECCCEEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCEEECCCHHHHHHCCCEEE
MASSPAAGTETRTFLQAPETMPNGERQFMRKCSVCHDLVATEQRRAGPHLAGLFGRPAGS
EECCCCCCCCCHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHCCCCCCC
LPGYRYSDTLAQSDIIWGAETIDALFDLGPDHYIPGSKMPMQRITAPTDRQDLIDYLKTA
CCCCCCHHHHHCCCEEECHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHH
TQLSEDN
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]