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The map label for this gene is mshA [H]

Identifier: 99080069

GI number: 99080069

Start: 242545

End: 243768

Strand: Direct

Name: mshA [H]

Synonym: TM1040_0228

Alternate gene names: 99080069

Gene position: 242545-243768 (Clockwise)

Preceding gene: 99080068

Following gene: 99080070

Centisome position: 7.58

GC content: 63.48

Gene sequence:

>1224_bases
ATGAAATTGCTCGTCGTATCGACGAATGCTGCCCTCACCATGGGGGGCGAGGCGATGAAGGCGCTGCAGTATATGCAGCA
GCTCTTGGCGGATGGACGCGATGCCACTCTCATCACCCATGAACGCTGTCGCGAGGCTCTTGCGGGGCAATTGCCAGAAG
ATCGGGTGATCTATGTGCATGACAGCCGTGCAATGAAGGCCTGTTGGCGCACGCCGGGGCTTGGGCGGTTGGTGAACAGT
TTTTTTCACCTCGAGGTCGCCCGGATCTGTCGCGGCTTTAACCCGAGCGAGGTGGTGATCCACTATCTTTGTCCGATCTC
CCCCGTCGAGCAGCGCTTCCCGCCGAAGGGGTATCGCTATGTCATCGGCCCGCTTTCAGGCAATATCTTCTACCCAGAGG
GGTTTCGACATCTTGCGGGGCGGGGGCTGCGCCTGCAGCATCAGGCGTATCGGCCTTTGCAGATGGCGCTTGGCCTCTTG
TCTAGGCAATTCACGCGCGCCTCGACCGTGTTGGTCTCTGGCTATGACCGTACCCGAGAGGCCCTCGGCTGGGCGGGTTG
CCCGGAGGCCCGCATGCAGGACGTCTGGGATGCGGGCCTGTCTCCAGATTTCTTTGCGCGTTCCCGGATCCGGCCGGGCA
AGAACCCGGCGCATTTTGTGTGGATTGGACGTATGGTGCCCTACAAGGGGGCGGATCTTGCGTTGCGCGCGCTGGCGCTT
GCCCCGGCAGAGGCACGGCTCACGCTCTATGGAGATGGGCCGGATCGTGCCGAACTGGAGGCGCTCGCCCGCGATCTTGG
CCTGATGTCGCGGGTCACCTTTGCGGGCTGGCTTGCGCATGGGGATCTCTCCGAGGCGTTGGGCCAGTACCGAGCACTTT
TGTTCCCGAGCCTCAAAGAAGCCAACGGCATCATCGTGCAGGAATGTATGGCGATCGGCTTGCCGGTCGTGGCCTTGCGC
TGGGGCGGGCCTGTGGGGCTCGCGGATGACACTGAGGCGCTGTTTGTCGAGGCGCAGAATGCCGTACAGGTCGAGCAGGA
CTTGGCTGCGGCCATGGCGCGTCTGACAGAAGACCCAGCCCTTGCGGAGGCGCTCTCTGATGCGGCGCGACGCAAGGCTG
AAAACGAGTTCCCCTGGCCGCAGGTGGCCCAAAGCTGGTGCAGCGCAGCGCTTCGCGCGCAGGATGCGGCTGCAGCAGAG
CCAAAGCACCGCGGCGGGGGTTGA

Upstream 100 bases:

>100_bases
GCGCCGGTTTCCGGCGCTACACGGAATTTCCCATTGGGAACTTGAGGATCGGCCCCTAAAATGGGGCCGATTTTTGTTTG
GTCCGCCGGAGTTCCCGCCC

Downstream 100 bases:

>100_bases
TCTCTGCAGAGATGGGGCGTATGAGCCGCCAATCTGCCCGGTTTCTCAACCGGGCGTGATTCTTGTGGGAGGCCCAAGCG
TCGCGACGTGTTGGGTCGAA

Product: glycosyl transferase, group 1

Products: NA

Alternate protein names: N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase; GlcNAc-Ins-P N-acetylglucosaminyltransferase [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MKLLVVSTNAALTMGGEAMKALQYMQQLLADGRDATLITHERCREALAGQLPEDRVIYVHDSRAMKACWRTPGLGRLVNS
FFHLEVARICRGFNPSEVVIHYLCPISPVEQRFPPKGYRYVIGPLSGNIFYPEGFRHLAGRGLRLQHQAYRPLQMALGLL
SRQFTRASTVLVSGYDRTREALGWAGCPEARMQDVWDAGLSPDFFARSRIRPGKNPAHFVWIGRMVPYKGADLALRALAL
APAEARLTLYGDGPDRAELEALARDLGLMSRVTFAGWLAHGDLSEALGQYRALLFPSLKEANGIIVQECMAIGLPVVALR
WGGPVGLADDTEALFVEAQNAVQVEQDLAAAMARLTEDPALAEALSDAARRKAENEFPWPQVAQSWCSAALRAQDAAAAE
PKHRGGG

Sequences:

>Translated_407_residues
MKLLVVSTNAALTMGGEAMKALQYMQQLLADGRDATLITHERCREALAGQLPEDRVIYVHDSRAMKACWRTPGLGRLVNS
FFHLEVARICRGFNPSEVVIHYLCPISPVEQRFPPKGYRYVIGPLSGNIFYPEGFRHLAGRGLRLQHQAYRPLQMALGLL
SRQFTRASTVLVSGYDRTREALGWAGCPEARMQDVWDAGLSPDFFARSRIRPGKNPAHFVWIGRMVPYKGADLALRALAL
APAEARLTLYGDGPDRAELEALARDLGLMSRVTFAGWLAHGDLSEALGQYRALLFPSLKEANGIIVQECMAIGLPVVALR
WGGPVGLADDTEALFVEAQNAVQVEQDLAAAMARLTEDPALAEALSDAARRKAENEFPWPQVAQSWCSAALRAQDAAAAE
PKHRGGG
>Mature_407_residues
MKLLVVSTNAALTMGGEAMKALQYMQQLLADGRDATLITHERCREALAGQLPEDRVIYVHDSRAMKACWRTPGLGRLVNS
FFHLEVARICRGFNPSEVVIHYLCPISPVEQRFPPKGYRYVIGPLSGNIFYPEGFRHLAGRGLRLQHQAYRPLQMALGLL
SRQFTRASTVLVSGYDRTREALGWAGCPEARMQDVWDAGLSPDFFARSRIRPGKNPAHFVWIGRMVPYKGADLALRALAL
APAEARLTLYGDGPDRAELEALARDLGLMSRVTFAGWLAHGDLSEALGQYRALLFPSLKEANGIIVQECMAIGLPVVALR
WGGPVGLADDTEALFVEAQNAVQVEQDLAAAMARLTEDPALAEALSDAARRKAENEFPWPQVAQSWCSAALRAQDAAAAE
PKHRGGG

Specific function: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway [H]

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family. MshA subfamily [H]

Homologues:

Organism=Caenorhabditis elegans, GI17532709, Length=211, Percent_Identity=28.436018957346, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR017814 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.250 [H]

Molecular weight: Translated: 44612; Mature: 44612

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLVVSTNAALTMGGEAMKALQYMQQLLADGRDATLITHERCREALAGQLPEDRVIYVH
CEEEEEECCCEEEECHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCCEEEEE
DSRAMKACWRTPGLGRLVNSFFHLEVARICRGFNPSEVVIHYLCPISPVEQRFPPKGYRY
CCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHEECCCCHHHHCCCCCCCEE
VIGPLSGNIFYPEGFRHLAGRGLRLQHQAYRPLQMALGLLSRQFTRASTVLVSGYDRTRE
EEEECCCCEECCCHHHHHHCCCCEECHHHCCHHHHHHHHHHHHHHHHHEEEEECCHHHHH
ALGWAGCPEARMQDVWDAGLSPDFFARSRIRPGKNPAHFVWIGRMVPYKGADLALRALAL
HHCCCCCCHHHHHHHHHCCCCCCHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHH
APAEARLTLYGDGPDRAELEALARDLGLMSRVTFAGWLAHGDLSEALGQYRALLFPSLKE
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHH
ANGIIVQECMAIGLPVVALRWGGPVGLADDTEALFVEAQNAVQVEQDLAAAMARLTEDPA
CCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCHH
LAEALSDAARRKAENEFPWPQVAQSWCSAALRAQDAAAAEPKHRGGG
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKLLVVSTNAALTMGGEAMKALQYMQQLLADGRDATLITHERCREALAGQLPEDRVIYVH
CEEEEEECCCEEEECHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCCEEEEE
DSRAMKACWRTPGLGRLVNSFFHLEVARICRGFNPSEVVIHYLCPISPVEQRFPPKGYRY
CCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHEECCCCHHHHCCCCCCCEE
VIGPLSGNIFYPEGFRHLAGRGLRLQHQAYRPLQMALGLLSRQFTRASTVLVSGYDRTRE
EEEECCCCEECCCHHHHHHCCCCEECHHHCCHHHHHHHHHHHHHHHHHEEEEECCHHHHH
ALGWAGCPEARMQDVWDAGLSPDFFARSRIRPGKNPAHFVWIGRMVPYKGADLALRALAL
HHCCCCCCHHHHHHHHHCCCCCCHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHH
APAEARLTLYGDGPDRAELEALARDLGLMSRVTFAGWLAHGDLSEALGQYRALLFPSLKE
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHH
ANGIIVQECMAIGLPVVALRWGGPVGLADDTEALFVEAQNAVQVEQDLAAAMARLTEDPA
CCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCHH
LAEALSDAARRKAENEFPWPQVAQSWCSAALRAQDAAAAEPKHRGGG
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]