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The map label for this gene is pyrF [H]

Identifier: 99079970

GI number: 99079970

Start: 136844

End: 137569

Strand: Reverse

Name: pyrF [H]

Synonym: TM1040_0129

Alternate gene names: 99079970

Gene position: 137569-136844 (Counterclockwise)

Preceding gene: 99079973

Following gene: 99079968

Centisome position: 4.3

GC content: 60.88

Gene sequence:

>726_bases
ATGACCAGCCCCCTCGCAGATGACCGCCTGATCGTTGCCATGGATGTTCCCAACGCCCTTGAAGGGCTCAAACTGGCGGA
ACAGCTGGGTGACGCGGTCTCATTCTACAAAATCGGCCTTGGGATGCTCACCGGGGGCGGGCTGGCCCTCGCAAATGAGT
TGAAGCAAGAGTTAGGTAAAAAGATCTTCCTCGACATGAAGCTCTTTGACATCGGGGCCACCGTGGAAAACGCGGTGCGC
GGATTGGCGCAGTTCGATCTCGACTTCCTGACCGTGCACGGCGACCCCTATGTGGTGCGCGCCGCAAAAGAAGGGGCTGC
GGGCAAGGATCTGAAGATCCTCGCCGTGACAATCCTTACGTCGCTGGATCGCGACGATCTGGATGGGGCGATGATCAAAT
CCGGTGAGATCAAAGATCTGGTGCAAGAGCGCGCCGGCAAGGCGTTCTCGGCTGGCGCAGATGGCGTCATTGCAAGCCCG
CAGGAAGCCGCCATGATCCGCTCCCTGCCCGAAGCAGAAGGCAAGCTGATCGTCACTCCTGGTGTGCGCCCGGTGGGCGC
TGACCTTGGCGACCAGAAGCGCGTTACAACCCCGGCGCAGGCTCTTGCTTCCGGCGTTGACCACATCGTTGTCGGTCGCC
CGATCTGGCAGGCGGAAGCACCCCGGGTAGCGGCAGAGTCAATTCTGCAAGAGATGAACAGCCCGCAGGCGAAAGCGCCG
AACTGA

Upstream 100 bases:

>100_bases
CCGGGATCAACTCTGGCAAAAAGCCACCGTCTCCCCTTTTCGAGGCCCTTCTAAGACAGTAGGAAGGCGCCAGCTTGCCC
TAAAAACCGGAGTATCCCCG

Downstream 100 bases:

>100_bases
GGCACGCGCAGCCACACGCCTGTTTTTTGTGCGCTCGACCCCGATAAACAAACGCAAACGCACCAAATAGCCCCGTTGCG
CCCTGCGGGGCCACCCTAAC

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase [H]

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MTSPLADDRLIVAMDVPNALEGLKLAEQLGDAVSFYKIGLGMLTGGGLALANELKQELGKKIFLDMKLFDIGATVENAVR
GLAQFDLDFLTVHGDPYVVRAAKEGAAGKDLKILAVTILTSLDRDDLDGAMIKSGEIKDLVQERAGKAFSAGADGVIASP
QEAAMIRSLPEAEGKLIVTPGVRPVGADLGDQKRVTTPAQALASGVDHIVVGRPIWQAEAPRVAAESILQEMNSPQAKAP
N

Sequences:

>Translated_241_residues
MTSPLADDRLIVAMDVPNALEGLKLAEQLGDAVSFYKIGLGMLTGGGLALANELKQELGKKIFLDMKLFDIGATVENAVR
GLAQFDLDFLTVHGDPYVVRAAKEGAAGKDLKILAVTILTSLDRDDLDGAMIKSGEIKDLVQERAGKAFSAGADGVIASP
QEAAMIRSLPEAEGKLIVTPGVRPVGADLGDQKRVTTPAQALASGVDHIVVGRPIWQAEAPRVAAESILQEMNSPQAKAP
N
>Mature_240_residues
TSPLADDRLIVAMDVPNALEGLKLAEQLGDAVSFYKIGLGMLTGGGLALANELKQELGKKIFLDMKLFDIGATVENAVRG
LAQFDLDFLTVHGDPYVVRAAKEGAAGKDLKILAVTILTSLDRDDLDGAMIKSGEIKDLVQERAGKAFSAGADGVIASPQ
EAAMIRSLPEAEGKLIVTPGVRPVGADLGDQKRVTTPAQALASGVDHIVVGRPIWQAEAPRVAAESILQEMNSPQAKAPN

Specific function: Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) [H]

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787537, Length=218, Percent_Identity=38.5321100917431, Blast_Score=113, Evalue=1e-26,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR014732
- InterPro:   IPR018089
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.23 [H]

Molecular weight: Translated: 25305; Mature: 25174

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00156 OMPDECASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPLADDRLIVAMDVPNALEGLKLAEQLGDAVSFYKIGLGMLTGGGLALANELKQELGK
CCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCH
KIFLDMKLFDIGATVENAVRGLAQFDLDFLTVHGDPYVVRAAKEGAAGKDLKILAVTILT
HEEEEEEEEECCCHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHH
SLDRDDLDGAMIKSGEIKDLVQERAGKAFSAGADGVIASPQEAAMIRSLPEAEGKLIVTP
HCCCCCCCCCEECCCCHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHCCCCCCCEEECC
GVRPVGADLGDQKRVTTPAQALASGVDHIVVGRPIWQAEAPRVAAESILQEMNSPQAKAP
CCCCCCCCCCCCCCCCCHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCC
N
C
>Mature Secondary Structure 
TSPLADDRLIVAMDVPNALEGLKLAEQLGDAVSFYKIGLGMLTGGGLALANELKQELGK
CCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCH
KIFLDMKLFDIGATVENAVRGLAQFDLDFLTVHGDPYVVRAAKEGAAGKDLKILAVTILT
HEEEEEEEEECCCHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHH
SLDRDDLDGAMIKSGEIKDLVQERAGKAFSAGADGVIASPQEAAMIRSLPEAEGKLIVTP
HCCCCCCCCCEECCCCHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHCCCCCCCEEECC
GVRPVGADLGDQKRVTTPAQALASGVDHIVVGRPIWQAEAPRVAAESILQEMNSPQAKAP
CCCCCCCCCCCCCCCCCHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCC
N
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA