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The map label for this gene is ydjE [C]

Identifier: 94995264

GI number: 94995264

Start: 1828396

End: 1829739

Strand: Direct

Name: ydjE [C]

Synonym: MGAS10750_Spy1868

Alternate gene names: 94995264

Gene position: 1828396-1829739 (Clockwise)

Preceding gene: 94995263

Following gene: 162139172

Centisome position: 94.39

GC content: 43.75

Gene sequence:

>1344_bases
ATGGCGTCAAATCACATGAACGAACAAGAAAGAGAACAGGCAAAGTTTAGCTTGAGCGGTGCCACTCTTTACGGGATCAA
TGCCGTTATCGGCTCTGGTATTTTTCTCTTACCTAGGGCCATTTACAAGGGCCTTGGCCCTGCATCCATCGCTGTTATGT
TTGGAACAGCTATTTTGACCATCATGTTGGCAGTTTGTTTTGCAGAAGTCTCTGGTTATTTTGGGAAAAACGGCGGGGCC
TTCCAATATTCCAAACGAGCTTTTGGTGATTTTATTGGCTTTAACGTTGGCTTCCTTGGTTGGACCGTTACCATCTTCGC
TTGGGCAGCCATGGCAGCTGGGTTTGCCAGAATGTTTATCATTACTTTCCCTGCCTTTGAAGGTTGGCACATTCCACTTA
GCATTGGGTTAATCATCTTACTATCTTTGATGAATATCGCTGGTTTGAAAACCTCTAAAATTGTCACCATCACAGCCACC
ATTGCTAAGTTAATTCCAATCGTTGCCTTTTGTGCCTGTACCCTTTTCTTCATCAAAAACGGGCTTCCTAACTTTACCCC
ATTTGTTCAGTTGGAACCAGGGACTAACCTCTTAGGGGCTATCTCCAATACTGCTGTTTATATCTTCTATGGCTTTATCG
GTTTTGAAACCCTCTCTATTGTCGCTGGGGAAATGCGTGACCCTGAAAAAAATGTACCGCGTGCTCTTTTAGGATCAATC
AGTATCGTCTCTGTCTTATATATGCTGATTATCGGTGGAACCATTGCCATGCTTGGCTCTCAAATCATGATGACCAATGC
ACCTGTTCAAGATGCCTTTGTTAAAATGATAGGCCCTGCTGGCGCTTGGATGGTCTCAATCGGTGCTTTAATTTCCATTA
CAGGTCTTAACATAGGAGAATCCATCATGGTGCCACGTTACGGTGCTGCCATTGCTGATGAAGGGCTCTTACCAGCTGCT
ATTGCCAAGCAAAATCAAAATGGCGCACCACTCGTTGCTATCTTGGTTTCAGGAGCAATTGCTATTGTACTCCTACTCAC
TGGCTCATTTGAAAACTTAGCAAAACTCAGTGTTATTTTCCGCTTCTTCCAATACATTCCAACAGCACTAGCCGTTATGA
AATTACGGAAGGACGATCCCGATGCTAATGTGATCTTCCGAGTACCATTTGGTCCTATTATCCCAATTCTTGCAGTTATC
GTTAGTTTAGTTATGATTTGGGGTGACAACCCAATGAACTTTGTTTATGGTGCAGTTGGTGTCATCATTGCAAGTAGTGT
GTACTACCTTATGCACGGACGTAACCACCAAATGGACCAAATGCCCCCTAAGGAACAAATCTAG

Upstream 100 bases:

>100_bases
GTGCAAGAAGGACCCTCCTAAACCGACTATCTCCTCATTTCCTAGCGACCTTATCCATTATATTTGAACGCAATTTGCAA
ACAAAAAGGAGAGCATTATT

Downstream 100 bases:

>100_bases
GAGAAAAACTATGACAAGAGTGATTAATTTAGATGGCGAAAGCCTTACTATCGAAGACGTGATTGCGATTGCTCGCCAAG
GCATAGCCTGTCGCATTGAT

Product: amino acid permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MASNHMNEQEREQAKFSLSGATLYGINAVIGSGIFLLPRAIYKGLGPASIAVMFGTAILTIMLAVCFAEVSGYFGKNGGA
FQYSKRAFGDFIGFNVGFLGWTVTIFAWAAMAAGFARMFIITFPAFEGWHIPLSIGLIILLSLMNIAGLKTSKIVTITAT
IAKLIPIVAFCACTLFFIKNGLPNFTPFVQLEPGTNLLGAISNTAVYIFYGFIGFETLSIVAGEMRDPEKNVPRALLGSI
SIVSVLYMLIIGGTIAMLGSQIMMTNAPVQDAFVKMIGPAGAWMVSIGALISITGLNIGESIMVPRYGAAIADEGLLPAA
IAKQNQNGAPLVAILVSGAIAIVLLLTGSFENLAKLSVIFRFFQYIPTALAVMKLRKDDPDANVIFRVPFGPIIPILAVI
VSLVMIWGDNPMNFVYGAVGVIIASSVYYLMHGRNHQMDQMPPKEQI

Sequences:

>Translated_447_residues
MASNHMNEQEREQAKFSLSGATLYGINAVIGSGIFLLPRAIYKGLGPASIAVMFGTAILTIMLAVCFAEVSGYFGKNGGA
FQYSKRAFGDFIGFNVGFLGWTVTIFAWAAMAAGFARMFIITFPAFEGWHIPLSIGLIILLSLMNIAGLKTSKIVTITAT
IAKLIPIVAFCACTLFFIKNGLPNFTPFVQLEPGTNLLGAISNTAVYIFYGFIGFETLSIVAGEMRDPEKNVPRALLGSI
SIVSVLYMLIIGGTIAMLGSQIMMTNAPVQDAFVKMIGPAGAWMVSIGALISITGLNIGESIMVPRYGAAIADEGLLPAA
IAKQNQNGAPLVAILVSGAIAIVLLLTGSFENLAKLSVIFRFFQYIPTALAVMKLRKDDPDANVIFRVPFGPIIPILAVI
VSLVMIWGDNPMNFVYGAVGVIIASSVYYLMHGRNHQMDQMPPKEQI
>Mature_446_residues
ASNHMNEQEREQAKFSLSGATLYGINAVIGSGIFLLPRAIYKGLGPASIAVMFGTAILTIMLAVCFAEVSGYFGKNGGAF
QYSKRAFGDFIGFNVGFLGWTVTIFAWAAMAAGFARMFIITFPAFEGWHIPLSIGLIILLSLMNIAGLKTSKIVTITATI
AKLIPIVAFCACTLFFIKNGLPNFTPFVQLEPGTNLLGAISNTAVYIFYGFIGFETLSIVAGEMRDPEKNVPRALLGSIS
IVSVLYMLIIGGTIAMLGSQIMMTNAPVQDAFVKMIGPAGAWMVSIGALISITGLNIGESIMVPRYGAAIADEGLLPAAI
AKQNQNGAPLVAILVSGAIAIVLLLTGSFENLAKLSVIFRFFQYIPTALAVMKLRKDDPDANVIFRVPFGPIIPILAVIV
SLVMIWGDNPMNFVYGAVGVIIASSVYYLMHGRNHQMDQMPPKEQI

Specific function: Probable amino-acid or metabolite transport protein [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI186910308, Length=412, Percent_Identity=24.7572815533981, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI186910306, Length=412, Percent_Identity=24.7572815533981, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI186910304, Length=412, Percent_Identity=24.7572815533981, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI71999149, Length=407, Percent_Identity=23.5872235872236, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI4507047, Length=212, Percent_Identity=28.3018867924528, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI33286428, Length=379, Percent_Identity=26.9129287598945, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI115648063, Length=443, Percent_Identity=23.7020316027088, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI115648022, Length=443, Percent_Identity=23.7020316027088, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI258614003, Length=402, Percent_Identity=23.3830845771144, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI258614005, Length=402, Percent_Identity=23.3830845771144, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI187423910, Length=428, Percent_Identity=21.7289719626168, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI7657591, Length=428, Percent_Identity=21.7289719626168, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI181337167, Length=391, Percent_Identity=24.8081841432225, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI258645169, Length=401, Percent_Identity=22.6932668329177, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI114326544, Length=180, Percent_Identity=24.4444444444444, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI114326550, Length=180, Percent_Identity=24.4444444444444, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI2367353, Length=450, Percent_Identity=27.1111111111111, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1787890, Length=461, Percent_Identity=22.7765726681128, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87082250, Length=460, Percent_Identity=23.4782608695652, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786908, Length=389, Percent_Identity=21.8508997429306, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1787768, Length=391, Percent_Identity=25.8312020460358, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1789017, Length=375, Percent_Identity=21.8666666666667, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788480, Length=432, Percent_Identity=25.6944444444444, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87081708, Length=458, Percent_Identity=22.707423580786, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786302, Length=404, Percent_Identity=23.019801980198, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71982612, Length=432, Percent_Identity=26.8518518518519, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71982608, Length=432, Percent_Identity=26.8518518518519, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17532491, Length=408, Percent_Identity=23.2843137254902, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17540018, Length=404, Percent_Identity=26.4851485148515, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI32566695, Length=444, Percent_Identity=25.2252252252252, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI193208714, Length=441, Percent_Identity=25.1700680272109, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17531343, Length=407, Percent_Identity=24.5700245700246, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71995382, Length=421, Percent_Identity=24.2280285035629, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71995388, Length=421, Percent_Identity=24.2280285035629, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71993915, Length=399, Percent_Identity=25.062656641604, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17533459, Length=410, Percent_Identity=24.1463414634146, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24668806, Length=412, Percent_Identity=24.2718446601942, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI21356285, Length=412, Percent_Identity=24.2718446601942, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24668802, Length=412, Percent_Identity=24.2718446601942, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI45550968, Length=437, Percent_Identity=24.0274599542334, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI19921172, Length=437, Percent_Identity=24.0274599542334, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24667468, Length=389, Percent_Identity=24.1645244215938, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24666159, Length=407, Percent_Identity=25.0614250614251, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI221512776, Length=407, Percent_Identity=25.0614250614251, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24651635, Length=429, Percent_Identity=23.0769230769231, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24651633, Length=429, Percent_Identity=23.0769230769231, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI221331183, Length=315, Percent_Identity=24.7619047619048, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17647653, Length=315, Percent_Identity=24.7619047619048, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24664379, Length=315, Percent_Identity=24.7619047619048, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI116007818, Length=409, Percent_Identity=24.4498777506112, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI85725152, Length=409, Percent_Identity=24.4498777506112, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161077963, Length=396, Percent_Identity=23.2323232323232, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281366235, Length=180, Percent_Identity=29.4444444444444, Blast_Score=65, Evalue=1e-10,
Organism=Drosophila melanogaster, GI116007820, Length=180, Percent_Identity=29.4444444444444, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 47862; Mature: 47730

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASNHMNEQEREQAKFSLSGATLYGINAVIGSGIFLLPRAIYKGLGPASIAVMFGTAILT
CCCCCCCHHHHHHHHHEECCCEEEEHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHH
IMLAVCFAEVSGYFGKNGGAFQYSKRAFGDFIGFNVGFLGWTVTIFAWAAMAAGFARMFI
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHE
ITFPAFEGWHIPLSIGLIILLSLMNIAGLKTSKIVTITATIAKLIPIVAFCACTLFFIKN
EEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHC
GLPNFTPFVQLEPGTNLLGAISNTAVYIFYGFIGFETLSIVAGEMRDPEKNVPRALLGSI
CCCCCCCEEEECCCCCHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
SIVSVLYMLIIGGTIAMLGSQIMMTNAPVQDAFVKMIGPAGAWMVSIGALISITGLNIGE
HHHHHHHHHHHHHHHHHHCCHHEECCCCHHHHHHHHHCCCHHHHHHHHHHHEEECCCCCC
SIMVPRYGAAIADEGLLPAAIAKQNQNGAPLVAILVSGAIAIVLLLTGSFENLAKLSVIF
CEECCCCCCHHCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
RFFQYIPTALAVMKLRKDDPDANVIFRVPFGPIIPILAVIVSLVMIWGDNPMNFVYGAVG
HHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VIIASSVYYLMHGRNHQMDQMPPKEQI
HHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ASNHMNEQEREQAKFSLSGATLYGINAVIGSGIFLLPRAIYKGLGPASIAVMFGTAILT
CCCCCCHHHHHHHHHEECCCEEEEHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHH
IMLAVCFAEVSGYFGKNGGAFQYSKRAFGDFIGFNVGFLGWTVTIFAWAAMAAGFARMFI
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHE
ITFPAFEGWHIPLSIGLIILLSLMNIAGLKTSKIVTITATIAKLIPIVAFCACTLFFIKN
EEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHC
GLPNFTPFVQLEPGTNLLGAISNTAVYIFYGFIGFETLSIVAGEMRDPEKNVPRALLGSI
CCCCCCCEEEECCCCCHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
SIVSVLYMLIIGGTIAMLGSQIMMTNAPVQDAFVKMIGPAGAWMVSIGALISITGLNIGE
HHHHHHHHHHHHHHHHHHCCHHEECCCCHHHHHHHHHCCCHHHHHHHHHHHEEECCCCCC
SIMVPRYGAAIADEGLLPAAIAKQNQNGAPLVAILVSGAIAIVLLLTGSFENLAKLSVIF
CEECCCCCCHHCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
RFFQYIPTALAVMKLRKDDPDANVIFRVPFGPIIPILAVIVSLVMIWGDNPMNFVYGAVG
HHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VIIASSVYYLMHGRNHQMDQMPPKEQI
HHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]