Click here to switch to the map view.

The map label for this gene is rnhC [H]

Identifier: 94995019

GI number: 94995019

Start: 1558947

End: 1559849

Strand: Direct

Name: rnhC [H]

Synonym: MGAS10750_Spy1623

Alternate gene names: 94995019

Gene position: 1558947-1559849 (Clockwise)

Preceding gene: 94995013

Following gene: 94995020

Centisome position: 80.48

GC content: 36.99

Gene sequence:

>903_bases
ATGAATACCTTAGTTTTGAAAATAGATGCTATACTGAGTAAACATTTAAAAAAACAGCTAGCCCCCTACACCATCAATAG
CCAAAATACCTATGTAGCCTTTGCTGCTAAAAAAAATGGGGTTACTGTTTTGCTGTACAAATCCGGAAAATTAGTTCTCC
AGGGAAACGGTGCAAATGCTTTAGCTCAAGAGCTTAATCTTCCAGTAGCTAAGACAGTTTTTGAAGCAAGCAACAATAGC
CAAGATATACCTATAATCGGCAGTGATGAGGTGGGTAATGGCTCTTATTTTGGTGGGATTGCTGTTGTGGCAAGTTTTGT
CGATCCTAAAGATCATTCCTTCCTGAAAAAGCTTGGGGTTGATGATTCTAAAAAATTATCGGATAAAACCATTCAACAGA
TTGCGCCTCTGTTAGAGAAACAAATACCTCATCAATCACTTCTCCTATCACCTAAAAAATATAACGAATTGGTTGGTAAA
AGTAAACCATATAATGCCATTTCTATCAAAGTTGCTCTTCATAACCAAGCTATTTTTTTGTTGTTACAAAAAGGCATTCA
ACCTAAACAAATTGTTATTGATGCTTTCACTAGCCAATCAAATTATGAAAAGCATCTAAAAAAGGAAAAAAGCCATTTCC
CAAATCCTCTAACCTTTCAAGAAAAGGCAGAAAGTCACTATTTGGCTGTGGCTGTTAGCTCTATCATTGCTAGAAATCTA
TTTTTAGACAATCTCGATCAATTAGGTCAAGATTTAGGTTACCAACTCCCAAGCGGTGCTGGTTCAGCTTCAGATAAAGT
TGCTAGCCAACTCTTAGCCGCTTATGGTATGTCTAGCTTAGAATATAGTGCTAAACTTCACTTCGCCAACACTCACAAAG
CGCAAGCGCTTCTCACTAAATAA

Upstream 100 bases:

>100_bases
CCATTGCCCTAACCTGTCTAAAAATTCGAGTCTCTGTTTTCTTTGTTAAATAAACTTATGAATTAACCATAGTCAACTAT
TTTATGTTAAAATAATTATT

Downstream 100 bases:

>100_bases
AAGGAATCATATGAAACAGTTTATTAAAGAATGGGGCCCATTCACTCTCTTTTTAATTCTCTTTGGTCTATCTCGTCTTT
TTTTGTGGCAGGCTGTTAAA

Product: ribonuclease HIII

Products: NA

Alternate protein names: RNase HIII [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MNTLVLKIDAILSKHLKKQLAPYTINSQNTYVAFAAKKNGVTVLLYKSGKLVLQGNGANALAQELNLPVAKTVFEASNNS
QDIPIIGSDEVGNGSYFGGIAVVASFVDPKDHSFLKKLGVDDSKKLSDKTIQQIAPLLEKQIPHQSLLLSPKKYNELVGK
SKPYNAISIKVALHNQAIFLLLQKGIQPKQIVIDAFTSQSNYEKHLKKEKSHFPNPLTFQEKAESHYLAVAVSSIIARNL
FLDNLDQLGQDLGYQLPSGAGSASDKVASQLLAAYGMSSLEYSAKLHFANTHKAQALLTK

Sequences:

>Translated_300_residues
MNTLVLKIDAILSKHLKKQLAPYTINSQNTYVAFAAKKNGVTVLLYKSGKLVLQGNGANALAQELNLPVAKTVFEASNNS
QDIPIIGSDEVGNGSYFGGIAVVASFVDPKDHSFLKKLGVDDSKKLSDKTIQQIAPLLEKQIPHQSLLLSPKKYNELVGK
SKPYNAISIKVALHNQAIFLLLQKGIQPKQIVIDAFTSQSNYEKHLKKEKSHFPNPLTFQEKAESHYLAVAVSSIIARNL
FLDNLDQLGQDLGYQLPSGAGSASDKVASQLLAAYGMSSLEYSAKLHFANTHKAQALLTK
>Mature_300_residues
MNTLVLKIDAILSKHLKKQLAPYTINSQNTYVAFAAKKNGVTVLLYKSGKLVLQGNGANALAQELNLPVAKTVFEASNNS
QDIPIIGSDEVGNGSYFGGIAVVASFVDPKDHSFLKKLGVDDSKKLSDKTIQQIAPLLEKQIPHQSLLLSPKKYNELVGK
SKPYNAISIKVALHNQAIFLLLQKGIQPKQIVIDAFTSQSNYEKHLKKEKSHFPNPLTFQEKAESHYLAVAVSSIIARNL
FLDNLDQLGQDLGYQLPSGAGSASDKVASQLLAAYGMSSLEYSAKLHFANTHKAQALLTK

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG1039

COG function: function code L; Ribonuclease HIII

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family. RnhC subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001352
- InterPro:   IPR004641
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01351 RNase_HII [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 32655; Mature: 32655

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTLVLKIDAILSKHLKKQLAPYTINSQNTYVAFAAKKNGVTVLLYKSGKLVLQGNGANA
CCEEEEEHHHHHHHHHHHHCCCEEECCCCEEEEEEECCCCEEEEEEECCEEEEECCCCHH
LAQELNLPVAKTVFEASNNSQDIPIIGSDEVGNGSYFGGIAVVASFVDPKDHSFLKKLGV
HHHHHCCCHHHHHHHCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCC
DDSKKLSDKTIQQIAPLLEKQIPHQSLLLSPKKYNELVGKSKPYNAISIKVALHNQAIFL
CCCHHHHHHHHHHHHHHHHHHCCHHHHEECCHHHHHHHCCCCCCCEEEEEEEECCHHHHH
LLQKGIQPKQIVIDAFTSQSNYEKHLKKEKSHFPNPLTFQEKAESHYLAVAVSSIIARNL
HHHHCCCCHHEEEEECCCCCHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHH
FLDNLDQLGQDLGYQLPSGAGSASDKVASQLLAAYGMSSLEYSAKLHFANTHKAQALLTK
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHCCCC
>Mature Secondary Structure
MNTLVLKIDAILSKHLKKQLAPYTINSQNTYVAFAAKKNGVTVLLYKSGKLVLQGNGANA
CCEEEEEHHHHHHHHHHHHCCCEEECCCCEEEEEEECCCCEEEEEEECCEEEEECCCCHH
LAQELNLPVAKTVFEASNNSQDIPIIGSDEVGNGSYFGGIAVVASFVDPKDHSFLKKLGV
HHHHHCCCHHHHHHHCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCC
DDSKKLSDKTIQQIAPLLEKQIPHQSLLLSPKKYNELVGKSKPYNAISIKVALHNQAIFL
CCCHHHHHHHHHHHHHHHHHHCCHHHHEECCHHHHHHHCCCCCCCEEEEEEEECCHHHHH
LLQKGIQPKQIVIDAFTSQSNYEKHLKKEKSHFPNPLTFQEKAESHYLAVAVSSIIARNL
HHHHCCCCHHEEEEECCCCCHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHH
FLDNLDQLGQDLGYQLPSGAGSASDKVASQLLAAYGMSSLEYSAKLHFANTHKAQALLTK
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]