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The map label for this gene is nrdF [H]

Identifier: 94994624

GI number: 94994624

Start: 1174423

End: 1175382

Strand: Direct

Name: nrdF [H]

Synonym: MGAS10750_Spy1228

Alternate gene names: 94994624

Gene position: 1174423-1175382 (Clockwise)

Preceding gene: 94994622

Following gene: 94994628

Centisome position: 60.63

GC content: 35.94

Gene sequence:

>960_bases
ATGACTACATATTATGAAGCAATTAACTGGAATGAAATCGAAGACGTCATTGACAAGTCAACTTGGGAAAAGTTGACCGA
ACAATTTTGGCTTGATACCCGTATCCCTTTATCAAATGACTTAGACGATTGGCGCAAACTTTCTCTTCAAGAAAAAGATC
TTGTTGGCAAGGTTTTTGGAGGATTAACCCTACTTGATACCATGCAATCAGAAACTGGTGTCGAAGCTATTCGTGCTGAT
GTTCGCACTCCTCACGAAGAAGCTGTCTTAAACAATATTCAATTCATGGAATCTGTTCACGCTAAATCTTATTCGTCTAT
CTTTTCAACCTTAAACACCAAAAAAGAAATTGAAGAGATCTTTGAGTGGACTAATAATAATGAGTTTCTTCAAGAAAAAG
CACGTATTATCAATAACATTTACGCTAATGGAGATGCCTTACAAAAGAAAGTTGCCTCAACATATCTCGAAACTTTCCTT
TTTTATTCTGGCTTTTTCACCCCTCTTTACTATTTGGGAAATAATAAGCTAGCAAATGTTGCTGAAATCATAAAACTAAT
TATTCGTGATGAATCTGTACATGGTACTTATATCGGTTACAAATTCCAGCTTGGTTTTAACGAACTACCAGAAGATGAGC
AAGAGAATTTTCGTGATTGGATGTATGACCTCCTTTATCAGCTGTATGAAAATGAAGAAAAATACACCAAAACGCTTTAT
GATGGCGTAGGGTGGACTGAAGAAGTTATGACCTTTTTACGCTACAATGCTAACAAAGCTCTTATGAATTTAGGACAAGA
TCCTTTATTCCCAGATACTGCAAACGATGTTAACCCAATTGTTATGAATGGTATTTCAACAGGAACATCAAACCATGACT
TTTTCTCACAGGTAGGGAATGGCTATCTTCTTGGTTCTGTAGAAGCTATGTCTGATGACGATTATAATTATGGACTCTAA

Upstream 100 bases:

>100_bases
CTATTTAAACTTATTATTACCGGTAGAACTTTGGTCGGTTCTACTGGTTTATCTCGATATCCTTAACGCACTTTACTACT
CTTTAGGAGATCATTTTTCT

Downstream 100 bases:

>100_bases
TAGTGCTCACGAGACTGATAATCTATCAGTCTCTCAGATTGAAGACAAACATCGATTTGGTGCTTGTCTTTTTTAGTGTT
TTTAGATAAAAATGGCTGTT

Product: ribonucleotide-diphosphate reductase subunit beta

Products: NA

Alternate protein names: Ribonucleotide reductase small subunit [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDWRKLSLQEKDLVGKVFGGLTLLDTMQSETGVEAIRAD
VRTPHEEAVLNNIQFMESVHAKSYSSIFSTLNTKKEIEEIFEWTNNNEFLQEKARIINNIYANGDALQKKVASTYLETFL
FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEDEQENFRDWMYDLLYQLYENEEKYTKTLY
DGVGWTEEVMTFLRYNANKALMNLGQDPLFPDTANDVNPIVMNGISTGTSNHDFFSQVGNGYLLGSVEAMSDDDYNYGL

Sequences:

>Translated_319_residues
MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDWRKLSLQEKDLVGKVFGGLTLLDTMQSETGVEAIRAD
VRTPHEEAVLNNIQFMESVHAKSYSSIFSTLNTKKEIEEIFEWTNNNEFLQEKARIINNIYANGDALQKKVASTYLETFL
FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEDEQENFRDWMYDLLYQLYENEEKYTKTLY
DGVGWTEEVMTFLRYNANKALMNLGQDPLFPDTANDVNPIVMNGISTGTSNHDFFSQVGNGYLLGSVEAMSDDDYNYGL
>Mature_318_residues
TTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDWRKLSLQEKDLVGKVFGGLTLLDTMQSETGVEAIRADV
RTPHEEAVLNNIQFMESVHAKSYSSIFSTLNTKKEIEEIFEWTNNNEFLQEKARIINNIYANGDALQKKVASTYLETFLF
YSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEDEQENFRDWMYDLLYQLYENEEKYTKTLYD
GVGWTEEVMTFLRYNANKALMNLGQDPLFPDTANDVNPIVMNGISTGTSNHDFFSQVGNGYLLGSVEAMSDDDYNYGL

Specific function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [H]

COG id: COG0208

COG function: function code F; Ribonucleotide reductase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonucleoside diphosphate reductase small chain family [H]

Homologues:

Organism=Escherichia coli, GI1789031, Length=312, Percent_Identity=49.3589743589744, Blast_Score=326, Evalue=1e-90,
Organism=Escherichia coli, GI1788567, Length=340, Percent_Identity=23.2352941176471, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009078
- InterPro:   IPR012348
- InterPro:   IPR000358 [H]

Pfam domain/function: PF00268 Ribonuc_red_sm [H]

EC number: =1.17.4.1 [H]

Molecular weight: Translated: 36953; Mature: 36821

Theoretical pI: Translated: 4.12; Mature: 4.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDWRKLSLQEKDLVGKVFG
CCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCHHHHHHHHHHH
GLTLLDTMQSETGVEAIRADVRTPHEEAVLNNIQFMESVHAKSYSSIFSTLNTKKEIEEI
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
FEWTNNNEFLQEKARIINNIYANGDALQKKVASTYLETFLFYSGFFTPLYYLGNNKLANV
HHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AEIIKLIIRDESVHGTYIGYKFQLGFNELPEDEQENFRDWMYDLLYQLYENEEKYTKTLY
HHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHH
DGVGWTEEVMTFLRYNANKALMNLGQDPLFPDTANDVNPIVMNGISTGTSNHDFFSQVGN
HCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHCCC
GYLLGSVEAMSDDDYNYGL
CEEEEEEHHCCCCCCCCCC
>Mature Secondary Structure 
TTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDWRKLSLQEKDLVGKVFG
CCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCHHHHHHHHHHH
GLTLLDTMQSETGVEAIRADVRTPHEEAVLNNIQFMESVHAKSYSSIFSTLNTKKEIEEI
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
FEWTNNNEFLQEKARIINNIYANGDALQKKVASTYLETFLFYSGFFTPLYYLGNNKLANV
HHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
AEIIKLIIRDESVHGTYIGYKFQLGFNELPEDEQENFRDWMYDLLYQLYENEEKYTKTLY
HHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHH
DGVGWTEEVMTFLRYNANKALMNLGQDPLFPDTANDVNPIVMNGISTGTSNHDFFSQVGN
HCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHCCC
GYLLGSVEAMSDDDYNYGL
CEEEEEEHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]