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The map label for this gene is fni [H]

Identifier: 94994173

GI number: 94994173

Start: 750255

End: 751334

Strand: Direct

Name: fni [H]

Synonym: MGAS10750_Spy0777

Alternate gene names: 94994173

Gene position: 750255-751334 (Clockwise)

Preceding gene: 94994172

Following gene: 94994176

Centisome position: 38.73

GC content: 41.94

Gene sequence:

>1080_bases
TTGCCTTTAATCAGGATGCTAGAGATACCCTTATTTCCAAATGGCAAGAAGCTGATATCGCATTACTTTATCAAGAAAGG
TGGGGAGAGAATGACTAACCGTAAAGATGATCACATCAAATATGCTCTCAAGTACCAATCGCCTTATAATGCTTTTGATG
ACATAGAACTCATACACCATTCCTTACCTAGCTATGATTTGTCTGATATTGATCTCAGTACTCATTTTGCTGGGCAAGAC
TTCGACTTTCCCTTTTACATCAATGCCATGACAGGAGGAAGTCAAAAAGGCAAAGCTGTCAATGAAAAATTGGCCAAAGT
AGCAGCAGCAACAGGGATTGTCATGGTGACAGGGTCTTATAGCGCTGCTTTAAAAAATCCTAACGACGATTCCTATCGTT
TACATGAGGTGGCAGATAACTTGAAACTAGCCACGAATATTGGTCTAGATAAACCTGTGGCGCTAGGACAACAAACGGTT
CAAGAAATGCAGCCCCTCTTTTTACAGGTTCATGTGAATGTGATGCAAGAGTTGCTGATGCCAGAGGGTGAGCGCGTCTT
TCATACCTGGAAAAAACACCTCGCTGAATACGCTAGTCAAATACCAGTTCCTGTCATTCTCAAAGAAGTTGGTTTTGGCA
TGGATGTCAATAGTATCAAGCTAGCACATGACCTAGGCATTCAAACCTTTGATATTTCAGGTAGAGGAGGAACTTCATTT
GCTTACATTGAAAATCAAAGAGGGGGAGACCGCTCTTACTTAAACGATTGGGGACAAACCACTGTTCAGTGCTTACTGAA
TGCACAAGGACTGATGGACCAAGTGGAAATCTTAGCTTCGGGTGGTGTCAGACACCCCTTGGACATGATTAAGTGTTTTG
TCTTAGGAGCACGTGCAGTGGGACTCTCACGCACCGTTTTAGAATTGGTCGAAAAATACCCAACCGAGCGTGTGATTGCT
ATCGTTAATGGCTGGAAAGAAGAATTAAAAATCATTATGTGTGCTCTTGACTGTAAAACTATTAAAGAATTAAAGGGAGT
CGACTACTTACTATATGGACGCTTGCAGCAGGTCAATTAG

Upstream 100 bases:

>100_bases
ATCTACCATCCTAAGCTAGTAACCTTGGTAGCTGCTTGTCAGAAGCAAGATGCTGTTGCTAAATCTTCAGGTTCTGGTGG
TGGAGATTGTGGCATCGCGC

Downstream 100 bases:

>100_bases
GCTTCATCACCTCTACAATAGTGTCACCTACTACAAAGATGATAGAGCTTTTTTAGAACATAATATAAAATATTTATAAA
TACCTCATCAAACTCAGAAT

Product: isopentenyl pyrophosphate isomerase

Products: NA

Alternate protein names: IPP isomerase; Isopentenyl pyrophosphate isomerase [H]

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MPLIRMLEIPLFPNGKKLISHYFIKKGGERMTNRKDDHIKYALKYQSPYNAFDDIELIHHSLPSYDLSDIDLSTHFAGQD
FDFPFYINAMTGGSQKGKAVNEKLAKVAAATGIVMVTGSYSAALKNPNDDSYRLHEVADNLKLATNIGLDKPVALGQQTV
QEMQPLFLQVHVNVMQELLMPEGERVFHTWKKHLAEYASQIPVPVILKEVGFGMDVNSIKLAHDLGIQTFDISGRGGTSF
AYIENQRGGDRSYLNDWGQTTVQCLLNAQGLMDQVEILASGGVRHPLDMIKCFVLGARAVGLSRTVLELVEKYPTERVIA
IVNGWKEELKIIMCALDCKTIKELKGVDYLLYGRLQQVN

Sequences:

>Translated_359_residues
MPLIRMLEIPLFPNGKKLISHYFIKKGGERMTNRKDDHIKYALKYQSPYNAFDDIELIHHSLPSYDLSDIDLSTHFAGQD
FDFPFYINAMTGGSQKGKAVNEKLAKVAAATGIVMVTGSYSAALKNPNDDSYRLHEVADNLKLATNIGLDKPVALGQQTV
QEMQPLFLQVHVNVMQELLMPEGERVFHTWKKHLAEYASQIPVPVILKEVGFGMDVNSIKLAHDLGIQTFDISGRGGTSF
AYIENQRGGDRSYLNDWGQTTVQCLLNAQGLMDQVEILASGGVRHPLDMIKCFVLGARAVGLSRTVLELVEKYPTERVIA
IVNGWKEELKIIMCALDCKTIKELKGVDYLLYGRLQQVN
>Mature_358_residues
PLIRMLEIPLFPNGKKLISHYFIKKGGERMTNRKDDHIKYALKYQSPYNAFDDIELIHHSLPSYDLSDIDLSTHFAGQDF
DFPFYINAMTGGSQKGKAVNEKLAKVAAATGIVMVTGSYSAALKNPNDDSYRLHEVADNLKLATNIGLDKPVALGQQTVQ
EMQPLFLQVHVNVMQELLMPEGERVFHTWKKHLAEYASQIPVPVILKEVGFGMDVNSIKLAHDLGIQTFDISGRGGTSFA
YIENQRGGDRSYLNDWGQTTVQCLLNAQGLMDQVEILASGGVRHPLDMIKCFVLGARAVGLSRTVLELVEKYPTERVIAI
VNGWKEELKIIMCALDCKTIKELKGVDYLLYGRLQQVN

Specific function: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) [H]

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IPP isomerase type 2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000262
- InterPro:   IPR011179 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =5.3.3.2 [H]

Molecular weight: Translated: 40159; Mature: 40028

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLIRMLEIPLFPNGKKLISHYFIKKGGERMTNRKDDHIKYALKYQSPYNAFDDIELIHH
CCCCEEEECCCCCCHHHHHHHHHHHCCCHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHH
SLPSYDLSDIDLSTHFAGQDFDFPFYINAMTGGSQKGKAVNEKLAKVAAATGIVMVTGSY
CCCCCCCCCCCCEECCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEECCC
SAALKNPNDDSYRLHEVADNLKLATNIGLDKPVALGQQTVQEMQPLFLQVHVNVMQELLM
HHEECCCCCCCCHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PEGERVFHTWKKHLAEYASQIPVPVILKEVGFGMDVNSIKLAHDLGIQTFDISGRGGTSF
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEHHHCCCEEEEECCCCCCEE
AYIENQRGGDRSYLNDWGQTTVQCLLNAQGLMDQVEILASGGVRHPLDMIKCFVLGARAV
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
GLSRTVLELVEKYPTERVIAIVNGWKEELKIIMCALDCKTIKELKGVDYLLYGRLQQVN
HHHHHHHHHHHHCCCCEEEEHHHCCHHHHEEEHHHHCHHHHHHHCCCCEEECCHHHCCC
>Mature Secondary Structure 
PLIRMLEIPLFPNGKKLISHYFIKKGGERMTNRKDDHIKYALKYQSPYNAFDDIELIHH
CCCEEEECCCCCCHHHHHHHHHHHCCCHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHH
SLPSYDLSDIDLSTHFAGQDFDFPFYINAMTGGSQKGKAVNEKLAKVAAATGIVMVTGSY
CCCCCCCCCCCCEECCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEECCC
SAALKNPNDDSYRLHEVADNLKLATNIGLDKPVALGQQTVQEMQPLFLQVHVNVMQELLM
HHEECCCCCCCCHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PEGERVFHTWKKHLAEYASQIPVPVILKEVGFGMDVNSIKLAHDLGIQTFDISGRGGTSF
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEHHHCCCEEEEECCCCCCEE
AYIENQRGGDRSYLNDWGQTTVQCLLNAQGLMDQVEILASGGVRHPLDMIKCFVLGARAV
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
GLSRTVLELVEKYPTERVIAIVNGWKEELKIIMCALDCKTIKELKGVDYLLYGRLQQVN
HHHHHHHHHHHHCCCCEEEEHHHCCHHHHEEEHHHHCHHHHHHHCCCCEEECCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]