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The map label for this gene is ftsK [H]

Identifier: 94993770

GI number: 94993770

Start: 376144

End: 378549

Strand: Direct

Name: ftsK [H]

Synonym: MGAS10750_Spy0374

Alternate gene names: 94993770

Gene position: 376144-378549 (Clockwise)

Preceding gene: 94993768

Following gene: 162139190

Centisome position: 19.42

GC content: 40.44

Gene sequence:

>2406_bases
ATGGTTAAAAGAAATCAAAGAAGAAAAAGTGCGCCTAAGAAGCGTCTGACAAAAGCAGAAGTGGAAAAGCAACGTGCCAT
TAAGAGGATGATTTTATCTGTTTTAATGGCTTTGTTGCTTATTTTTGCGATGCTTCGCTTGGGCGTCTTTGGCGTGACAA
CTTATAATATGATTCGTTTTTTGGTGGGTAGTTTAGCCTATCCGTTTATGTTTGCCTGGTTAATTTACTTATTTTGTTTT
AAATGGTTACGGCAAAAAGATGGAATGATTGCGGGAGTTGTTATTGCCTTTTTGGGATTGCTAGTTGAGTGGCACGCCTT
CTTATTTGCGATGCCTAGGATGCTTGATCAAGATATTTTTCTAGGCACTGCGCGGCTAATTACAAGAGATTTACTAGCCC
TGCGCGTGACTGAATTTGTTGGTGGAGGAATGCTTGGTGCATTACTTTATAAACCCATAGCCTTTTTATTTTCGAATATC
GGCTCTTACTTTATTGGTTTTTTGTTTATCTTATTAGGATTATTTCTAATGACGCCTTGGGATATCTATGATGTGAGTCA
CCTTGTGAAAGAGGCTGTTGATAAACTAGCAGTGGCTTATCAGGAAAATAAAGAAAAGCGGTTCATCAAACGAGAAGAGC
ACCGCTTACAAGCTGAAAAAGAGGCTTTAGAGAAACAAGCACAAGAGGAAGAAAAACGTCTAGCAGAATTGACGGTTGAT
CCTGAGACGGGAGAGATTGTTGAGGATAGTCAGTCTCAAGTCAGCTATGATTTGGCTGAGGATATGACAAAAGAGCCAGA
GATTCTTGCTTATGATAGTCACCTCAAAGACGATGAGGCAAGCTTATTTGACCAAGAAGACTTGGCTTATGCTCATGAGG
AAATTGGGGCTTATGACTCTTTATCTGCTTTAGCATCTTCTGAAGATGAGATGGATATGGATGAACCTGTTGAAGTTGAT
TTCACACCAAAAACCCATCTTCTTTATAAACTTCCAACGATAGATTTATTTGCACCAGATAAGCCCAAAAACCAGTCCAA
AGAGAAAAACTTAGTCCGCAAAAATATCAAGGTGCTTGAAGATACCTTCCAAAGTTTTGGGATTGATGTCAAGGTAGAAC
GAGCAGAAATCGGGCCTTCCGTCACCAAATATGAAATTAAACCAGCTGTCGGGGTCCGAGTTAATCGTATTTCAAATCTT
GCTGATGATTTGGCACTTGCTCTGGCTGCTAAAGATGTTCGTATTGAAGCACCAATTCCTGGAAAATCATTAATAGGTAT
TGAAGTTCCTAACTCAGAAATTGCAACGGTTTCTTTCCGCGAACTTTGGGAACAATCTGATGCCAATCCTGAAAACCTTT
TAGAAGTACCACTAGGTAAAGCTGTTAATGGCAACGCTCGCAGTTTTAACTTAGCTAGAATGCCGCATCTTTTGGTAGCT
GGGTCAACTGGTTCAGGTAAATCTGTGGCAGTTAATGGCATTATTTCAAGTATTTTGATGAAGGCACGTCCAGATCAAGT
TAAGTTTATGATGATTGACCCCAAAATGGTTGAATTATCTGTTTATAATGATATTCCACATTTATTAATCCCTGTTGTAA
CCAATCCGCGTAAAGCCAGTAAGGCACTCCAAAAAGTGGTTGATGAGATGGAAAACCGCTACGAGTTATTTAGTAAAATT
GGTGTGCGTAATATAGCAGGTTATAATACAAAGGTTGAAGAGTTTAATGCTTCTTCTGAGCAAAAACAAATACCGTTGCC
TTTAATCGTTGTCATTGTAGATGAATTGGCTGACTTGATGATGGTTGCTAGTAAAGAAGTTGAAGATGCTATTATTCGTT
TGGGGCAAAAAGCGCGTGCGGCAGGTATCCATATGATTCTTGCAACTCAACGTCCCTCTGTAGATGTTATTTCTGGTTTG
ATTAAAGCAAATGTTCCTTCGCGTATGGCATTTGCTGTTTCAAGTGGTACTGATAGCCGTACGATCCTTGATGAAAATGG
TGCTGAAAAGCTCTTGGGACGGGGTGATATGCTCTTTAAGCCGATTGATGAAAATCACCCTGTTCGCTTGCAAGGGTCTT
TCATCTCAGATGATGATGTGGAGCGTATTGTCAACTTTATCAAAGACCAAGCTGAAGCGGATTATGATGACGCCTTTGAT
CCTGGTGAAGTTAGCGACAATGATCCTGGTTTTTCTGGAAATGGCGGAGCTGCTGAAGGTGATCCTCTTTTTGAAGAAGC
AAAAGCCTTGGTCTTAGAGACACAAAAAGCTAGTGCCTCAATGATTCAAAGGCGTTTGTCGGTTGGATTTAATCGTGCCA
CGCGCTTGATGGATGAATTGGAAGAAGCAGGTGTTATCGGTCCAGCAGAAGGAACCAAACCTCGTAAGGTATTGCAGACA
AACTAA

Upstream 100 bases:

>100_bases
CTACGACTGTTATTATAGCACAAGATGCTATAGAAAAACTTAAAATACCTTGGTTTTTTAGAGCTATTTCCTAATAGTTA
AAAAATGGTATAATAGTGTT

Downstream 100 bases:

>100_bases
AAGAACCTGACGTCTCATAATGAGATGTCAGGTTCTTTTTTTGTGATGTCAGGCCAGTTGATGAGATGCCTATGCTAATG
TAAAAATAAAGATAACTAGA

Product: cell division protein ftsK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 801; Mature: 801

Protein sequence:

>801_residues
MVKRNQRRKSAPKKRLTKAEVEKQRAIKRMILSVLMALLLIFAMLRLGVFGVTTYNMIRFLVGSLAYPFMFAWLIYLFCF
KWLRQKDGMIAGVVIAFLGLLVEWHAFLFAMPRMLDQDIFLGTARLITRDLLALRVTEFVGGGMLGALLYKPIAFLFSNI
GSYFIGFLFILLGLFLMTPWDIYDVSHLVKEAVDKLAVAYQENKEKRFIKREEHRLQAEKEALEKQAQEEEKRLAELTVD
PETGEIVEDSQSQVSYDLAEDMTKEPEILAYDSHLKDDEASLFDQEDLAYAHEEIGAYDSLSALASSEDEMDMDEPVEVD
FTPKTHLLYKLPTIDLFAPDKPKNQSKEKNLVRKNIKVLEDTFQSFGIDVKVERAEIGPSVTKYEIKPAVGVRVNRISNL
ADDLALALAAKDVRIEAPIPGKSLIGIEVPNSEIATVSFRELWEQSDANPENLLEVPLGKAVNGNARSFNLARMPHLLVA
GSTGSGKSVAVNGIISSILMKARPDQVKFMMIDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKI
GVRNIAGYNTKVEEFNASSEQKQIPLPLIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGIHMILATQRPSVDVISGL
IKANVPSRMAFAVSSGTDSRTILDENGAEKLLGRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKDQAEADYDDAFD
PGEVSDNDPGFSGNGGAAEGDPLFEEAKALVLETQKASASMIQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVLQT
N

Sequences:

>Translated_801_residues
MVKRNQRRKSAPKKRLTKAEVEKQRAIKRMILSVLMALLLIFAMLRLGVFGVTTYNMIRFLVGSLAYPFMFAWLIYLFCF
KWLRQKDGMIAGVVIAFLGLLVEWHAFLFAMPRMLDQDIFLGTARLITRDLLALRVTEFVGGGMLGALLYKPIAFLFSNI
GSYFIGFLFILLGLFLMTPWDIYDVSHLVKEAVDKLAVAYQENKEKRFIKREEHRLQAEKEALEKQAQEEEKRLAELTVD
PETGEIVEDSQSQVSYDLAEDMTKEPEILAYDSHLKDDEASLFDQEDLAYAHEEIGAYDSLSALASSEDEMDMDEPVEVD
FTPKTHLLYKLPTIDLFAPDKPKNQSKEKNLVRKNIKVLEDTFQSFGIDVKVERAEIGPSVTKYEIKPAVGVRVNRISNL
ADDLALALAAKDVRIEAPIPGKSLIGIEVPNSEIATVSFRELWEQSDANPENLLEVPLGKAVNGNARSFNLARMPHLLVA
GSTGSGKSVAVNGIISSILMKARPDQVKFMMIDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKI
GVRNIAGYNTKVEEFNASSEQKQIPLPLIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGIHMILATQRPSVDVISGL
IKANVPSRMAFAVSSGTDSRTILDENGAEKLLGRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKDQAEADYDDAFD
PGEVSDNDPGFSGNGGAAEGDPLFEEAKALVLETQKASASMIQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVLQT
N
>Mature_801_residues
MVKRNQRRKSAPKKRLTKAEVEKQRAIKRMILSVLMALLLIFAMLRLGVFGVTTYNMIRFLVGSLAYPFMFAWLIYLFCF
KWLRQKDGMIAGVVIAFLGLLVEWHAFLFAMPRMLDQDIFLGTARLITRDLLALRVTEFVGGGMLGALLYKPIAFLFSNI
GSYFIGFLFILLGLFLMTPWDIYDVSHLVKEAVDKLAVAYQENKEKRFIKREEHRLQAEKEALEKQAQEEEKRLAELTVD
PETGEIVEDSQSQVSYDLAEDMTKEPEILAYDSHLKDDEASLFDQEDLAYAHEEIGAYDSLSALASSEDEMDMDEPVEVD
FTPKTHLLYKLPTIDLFAPDKPKNQSKEKNLVRKNIKVLEDTFQSFGIDVKVERAEIGPSVTKYEIKPAVGVRVNRISNL
ADDLALALAAKDVRIEAPIPGKSLIGIEVPNSEIATVSFRELWEQSDANPENLLEVPLGKAVNGNARSFNLARMPHLLVA
GSTGSGKSVAVNGIISSILMKARPDQVKFMMIDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKI
GVRNIAGYNTKVEEFNASSEQKQIPLPLIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGIHMILATQRPSVDVISGL
IKANVPSRMAFAVSSGTDSRTILDENGAEKLLGRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKDQAEADYDDAFD
PGEVSDNDPGFSGNGGAAEGDPLFEEAKALVLETQKASASMIQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVLQT
N

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=487, Percent_Identity=46.2012320328542, Blast_Score=402, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 89263; Mature: 89263

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKRNQRRKSAPKKRLTKAEVEKQRAIKRMILSVLMALLLIFAMLRLGVFGVTTYNMIRF
CCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVGSLAYPFMFAWLIYLFCFKWLRQKDGMIAGVVIAFLGLLVEWHAFLFAMPRMLDQDIF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGTARLITRDLLALRVTEFVGGGMLGALLYKPIAFLFSNIGSYFIGFLFILLGLFLMTPW
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DIYDVSHLVKEAVDKLAVAYQENKEKRFIKREEHRLQAEKEALEKQAQEEEKRLAELTVD
CHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
PETGEIVEDSQSQVSYDLAEDMTKEPEILAYDSHLKDDEASLFDQEDLAYAHEEIGAYDS
CCCCCHHCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHCCHHHHHHHHHHHCCHHH
LSALASSEDEMDMDEPVEVDFTPKTHLLYKLPTIDLFAPDKPKNQSKEKNLVRKNIKVLE
HHHHHCCCCCCCCCCCCEEECCCCCEEEEECCEEEEECCCCCCCCHHHHHHHHHHHHHHH
DTFQSFGIDVKVERAEIGPSVTKYEIKPAVGVRVNRISNLADDLALALAAKDVRIEAPIP
HHHHHCCCCEEEEHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCC
GKSLIGIEVPNSEIATVSFRELWEQSDANPENLLEVPLGKAVNGNARSFNLARMPHLLVA
CCCEEEEECCCCCEEEEHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCEEHHHCCEEEEE
GSTGSGKSVAVNGIISSILMKARPDQVKFMMIDPKMVELSVYNDIPHLLIPVVTNPRKAS
CCCCCCCCEEHHHHHHHHHHHCCCCCEEEEEECCEEEEEEECCCCCCCEEECCCCCHHHH
KALQKVVDEMENRYELFSKIGVRNIAGYNTKVEEFNASSEQKQIPLPLIVVIVDELADLM
HHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
MVASKEVEDAIIRLGQKARAAGIHMILATQRPSVDVISGLIKANVPSRMAFAVSSGTDSR
HHHHHHHHHHHHHHCCHHHHCCEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEECCCCCC
TILDENGAEKLLGRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKDQAEADYDDAFD
EEECCCCHHHHHCCCCCEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCC
PGEVSDNDPGFSGNGGAAEGDPLFEEAKALVLETQKASASMIQRRLSVGFNRATRLMDEL
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
EEAGVIGPAEGTKPRKVLQTN
HHCCCCCCCCCCCCCHHCCCC
>Mature Secondary Structure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HHCCCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]