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The map label for this gene is bacA [H]

Identifier: 94993631

GI number: 94993631

Start: 246474

End: 247313

Strand: Direct

Name: bacA [H]

Synonym: MGAS10750_Spy0235

Alternate gene names: 94993631

Gene position: 246474-247313 (Clockwise)

Preceding gene: 94993630

Following gene: 94993632

Centisome position: 12.72

GC content: 37.38

Gene sequence:

>840_bases
ATGTTAATAATCGAATTGCTAAAAGCCATTTTCTTTGGCATCATTGAGGGAATCACAGAATGGTTACCAGTTTCAAGCAC
TGGTCACCTCATTTTAGTGCAGGAATTTATCCGACTAAATCAGGATAAGGCTTTTATAGAAATGTTTAATATCGTTATAC
AACTAGGGGCGATTATCGCTGTTATGTTGATTTATTTTGAACGTCTCAATCCCTTCCAACCTGGGAAAACAGCAAGAGAA
GTACAGCTTACCTGGCAATTATGGCTAAAAGTGGTGATTGCGTGTATTCCTTCTATTTTAATAGCGGTTCCTCTTGATAA
TTGGTTTGAAGCACATTTTTATTTTATGGTTCCGATTGCCATCGCTTTAATCGTCTACGGGATTGCCTTTATCTGGATTG
AAAAACAAAATGCTCAACAAGAACCTGCCGTCACTGACTTAGCTAGAATGTCTTACAAAACAGCTTTCTTCATTGGTTGT
TTTCAAGTCTTAAGTATTGTGCCTGGTACTAGTCGATCAGGGGCTACCATCTTAGGAGCTATTATTTTAGGAACTAGTCG
AACAGTGGCCGCTGATTTCACCTTCTTTTTGGCCATTCCTACCATGTTTGGATATAGTGGATTAAAGGCTGTGAAATTTT
TCCTTGATGGCCATCACCTTGATTTTGCACAAGTCCTTATTCTTTTAGTGGCTAGCTTGACCGCTTTTGTGGTTAGTTTA
TTGGCGATTAGGTTCTTGACAGATTATGTTAAGAAACACGATTTCACCATTTTTGGGAAATACCGTATTGTGTTAGGAAG
CCTTTTACTTATTTATAGCTTCTTTAAATTTGTTTTTTAA

Upstream 100 bases:

>100_bases
GCGGTGGCGGAGGAGGCGGCGGCGGTGCCTTTTAAAAAAGCTGCTTGGCATTAATCACAGTTTAGAAAATCACAATAAGA
GTGGTTAATAAGGAGAAAAC

Downstream 100 bases:

>100_bases
ACTTACATATCGTTTAGGATGTTGCGACAGACCTTGGGGACTGTCGCTTTTTAAATTTCCTTTTGTAGAAGAGGAGTTAG
TCATAAATTGCGAAATTACA

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MLIIELLKAIFFGIIEGITEWLPVSSTGHLILVQEFIRLNQDKAFIEMFNIVIQLGAIIAVMLIYFERLNPFQPGKTARE
VQLTWQLWLKVVIACIPSILIAVPLDNWFEAHFYFMVPIAIALIVYGIAFIWIEKQNAQQEPAVTDLARMSYKTAFFIGC
FQVLSIVPGTSRSGATILGAIILGTSRTVAADFTFFLAIPTMFGYSGLKAVKFFLDGHHLDFAQVLILLVASLTAFVVSL
LAIRFLTDYVKKHDFTIFGKYRIVLGSLLLIYSFFKFVF

Sequences:

>Translated_279_residues
MLIIELLKAIFFGIIEGITEWLPVSSTGHLILVQEFIRLNQDKAFIEMFNIVIQLGAIIAVMLIYFERLNPFQPGKTARE
VQLTWQLWLKVVIACIPSILIAVPLDNWFEAHFYFMVPIAIALIVYGIAFIWIEKQNAQQEPAVTDLARMSYKTAFFIGC
FQVLSIVPGTSRSGATILGAIILGTSRTVAADFTFFLAIPTMFGYSGLKAVKFFLDGHHLDFAQVLILLVASLTAFVVSL
LAIRFLTDYVKKHDFTIFGKYRIVLGSLLLIYSFFKFVF
>Mature_279_residues
MLIIELLKAIFFGIIEGITEWLPVSSTGHLILVQEFIRLNQDKAFIEMFNIVIQLGAIIAVMLIYFERLNPFQPGKTARE
VQLTWQLWLKVVIACIPSILIAVPLDNWFEAHFYFMVPIAIALIVYGIAFIWIEKQNAQQEPAVTDLARMSYKTAFFIGC
FQVLSIVPGTSRSGATILGAIILGTSRTVAADFTFFLAIPTMFGYSGLKAVKFFLDGHHLDFAQVLILLVASLTAFVVSL
LAIRFLTDYVKKHDFTIFGKYRIVLGSLLLIYSFFKFVF

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin [H]

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family [H]

Homologues:

Organism=Escherichia coli, GI1789437, Length=275, Percent_Identity=35.2727272727273, Blast_Score=149, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003824 [H]

Pfam domain/function: PF02673 BacA [H]

EC number: =3.6.1.27 [H]

Molecular weight: Translated: 31496; Mature: 31496

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure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HHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]