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The map label for this gene is tatD [H]

Identifier: 94993611

GI number: 94993611

Start: 225527

End: 226414

Strand: Direct

Name: tatD [H]

Synonym: MGAS10750_Spy0215

Alternate gene names: 94993611

Gene position: 225527-226414 (Clockwise)

Preceding gene: 94993609

Following gene: 94993612

Centisome position: 11.64

GC content: 42.79

Gene sequence:

>888_bases
GTGTCAGCTAGCAAAGGGTTTTACGATCAACCTAAACGGCAGAAGTTCTCACCAAGTTTTCTGATGTGGTTAAGATCTTT
ATGTTATAATAACATCATGACAAATAAAGTAGAAAAACTAACTATTTTTGATACCCATACGCACCTGAATGTAGCAGAAT
TTCAAGGACACGAAACTGAAGAATTGACTTTGGCTCAAGAAATGGGCGTGGCCTACCATAATGTGGTTGGCTTTGACCAG
GCCACTATTAGTGGGGCACTAACTCTAGCCAATAAATATGCCAATATTTATGCAACTATTGGGTGGCATCCAACAGAAGC
AGGTTCTTATTCAGAGGCTGTTGAGGAGGCTATCGTCTCTCAATTATCACATCCCAAAGTGATTGCCTTAGGTGAAATTG
GCTTAGACTATTATTGGATGGAGGACCCCAAAGAGGTGCAAATAGAGGTTTTTAAGCGCCAAATGCAATTAGCAAAAGAC
CATGATTTGCCTTTTGTGGTGCACACCCGCGATGCCTTGGAAGATACCTATGAGGTCATCAAAGCAGCTGGTGTTGGCCC
CCGTGGAGGCATCATGCATTCTTACTCAGGGTCATTAGAGATGGCTGAACGTTTCATTGAACTTGGCATGATGATTTCCT
TTTCAGGTGTGGTCACTTTCAAAAAGGCTCTTGATATTCAAGAGGCAGCGCAGCACTTGCCTTTGGATAAGATTTTGGTG
GAAACAGATGCCCCTTATCTTACACCAGTTCCAAAACGTGGCAAACAAAATCATACAGCTTATACCCGTTATGTGGTTGA
TAAAATCGCAGAGCTACGGGGGATGACTGTGGAAGAAGTTGCAAAAGCAACGACTGCTAATGCAAAGAGGGTATTCAAGC
TTGACTGA

Upstream 100 bases:

>100_bases
TGTTCAACCCACTTTATTTGAGTAGGTTGTAGTATTTTTGAGGGCTTATGTAGGAGCCGACTATTAAAGGTCATTTGTCA
AAAAAGTAGAAAATAGACAA

Downstream 100 bases:

>100_bases
AAAAATTAATATTCAAGAGGTTCTTGTTGTAGAAGGCAAGGACGACACGGCTAACCTACGCCGTTTTTACGAGGTGGATA
CCTATGAGACTAGAGGCTCT

Product: DNase, TatD family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MSASKGFYDQPKRQKFSPSFLMWLRSLCYNNIMTNKVEKLTIFDTHTHLNVAEFQGHETEELTLAQEMGVAYHNVVGFDQ
ATISGALTLANKYANIYATIGWHPTEAGSYSEAVEEAIVSQLSHPKVIALGEIGLDYYWMEDPKEVQIEVFKRQMQLAKD
HDLPFVVHTRDALEDTYEVIKAAGVGPRGGIMHSYSGSLEMAERFIELGMMISFSGVVTFKKALDIQEAAQHLPLDKILV
ETDAPYLTPVPKRGKQNHTAYTRYVVDKIAELRGMTVEEVAKATTANAKRVFKLD

Sequences:

>Translated_295_residues
MSASKGFYDQPKRQKFSPSFLMWLRSLCYNNIMTNKVEKLTIFDTHTHLNVAEFQGHETEELTLAQEMGVAYHNVVGFDQ
ATISGALTLANKYANIYATIGWHPTEAGSYSEAVEEAIVSQLSHPKVIALGEIGLDYYWMEDPKEVQIEVFKRQMQLAKD
HDLPFVVHTRDALEDTYEVIKAAGVGPRGGIMHSYSGSLEMAERFIELGMMISFSGVVTFKKALDIQEAAQHLPLDKILV
ETDAPYLTPVPKRGKQNHTAYTRYVVDKIAELRGMTVEEVAKATTANAKRVFKLD
>Mature_294_residues
SASKGFYDQPKRQKFSPSFLMWLRSLCYNNIMTNKVEKLTIFDTHTHLNVAEFQGHETEELTLAQEMGVAYHNVVGFDQA
TISGALTLANKYANIYATIGWHPTEAGSYSEAVEEAIVSQLSHPKVIALGEIGLDYYWMEDPKEVQIEVFKRQMQLAKDH
DLPFVVHTRDALEDTYEVIKAAGVGPRGGIMHSYSGSLEMAERFIELGMMISFSGVVTFKKALDIQEAAQHLPLDKILVE
TDAPYLTPVPKRGKQNHTAYTRYVVDKIAELRGMTVEEVAKATTANAKRVFKLD

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI225903424, Length=206, Percent_Identity=36.4077669902913, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI14042943, Length=190, Percent_Identity=29.4736842105263, Blast_Score=101, Evalue=9e-22,
Organism=Homo sapiens, GI225903439, Length=169, Percent_Identity=30.1775147928994, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI110349730, Length=265, Percent_Identity=26.4150943396226, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI226061853, Length=270, Percent_Identity=26.2962962962963, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI110349734, Length=265, Percent_Identity=26.4150943396226, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI226061614, Length=256, Percent_Identity=25.390625, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI226061595, Length=227, Percent_Identity=25.5506607929515, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1787342, Length=258, Percent_Identity=36.046511627907, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI87082439, Length=256, Percent_Identity=33.203125, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI48994985, Length=258, Percent_Identity=29.4573643410853, Blast_Score=130, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17559024, Length=281, Percent_Identity=28.4697508896797, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI71980746, Length=268, Percent_Identity=26.865671641791, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17543026, Length=215, Percent_Identity=30.6976744186047, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17565396, Length=222, Percent_Identity=29.2792792792793, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24586117, Length=188, Percent_Identity=33.5106382978723, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI221330018, Length=188, Percent_Identity=33.5106382978723, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24648690, Length=295, Percent_Identity=26.7796610169492, Blast_Score=86, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 33139; Mature: 33008

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS01137 TATD_1 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASKGFYDQPKRQKFSPSFLMWLRSLCYNNIMTNKVEKLTIFDTHTHLNVAEFQGHETE
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHCCCCCH
ELTLAQEMGVAYHNVVGFDQATISGALTLANKYANIYATIGWHPTEAGSYSEAVEEAIVS
HHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHH
QLSHPKVIALGEIGLDYYWMEDPKEVQIEVFKRQMQLAKDHDLPFVVHTRDALEDTYEVI
HCCCCCEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHH
KAAGVGPRGGIMHSYSGSLEMAERFIELGMMISFSGVVTFKKALDIQEAAQHLPLDKILV
HHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEECHHHHHHHHHCHHHHHHHCCHHHEEE
ETDAPYLTPVPKRGKQNHTAYTRYVVDKIAELRGMTVEEVAKATTANAKRVFKLD
ECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEECC
>Mature Secondary Structure 
SASKGFYDQPKRQKFSPSFLMWLRSLCYNNIMTNKVEKLTIFDTHTHLNVAEFQGHETE
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHCCCCCH
ELTLAQEMGVAYHNVVGFDQATISGALTLANKYANIYATIGWHPTEAGSYSEAVEEAIVS
HHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHH
QLSHPKVIALGEIGLDYYWMEDPKEVQIEVFKRQMQLAKDHDLPFVVHTRDALEDTYEVI
HCCCCCEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHH
KAAGVGPRGGIMHSYSGSLEMAERFIELGMMISFSGVVTFKKALDIQEAAQHLPLDKILV
HHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEECHHHHHHHHHCHHHHHHHCCHHHEEE
ETDAPYLTPVPKRGKQNHTAYTRYVVDKIAELRGMTVEEVAKATTANAKRVFKLD
ECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]