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The map label for this gene is ycfX [C]

Identifier: 94993609

GI number: 94993609

Start: 223459

End: 224397

Strand: Direct

Name: ycfX [C]

Synonym: MGAS10750_Spy0213

Alternate gene names: 94993609

Gene position: 223459-224397 (Clockwise)

Preceding gene: 94993608

Following gene: 94993611

Centisome position: 11.54

GC content: 41.43

Gene sequence:

>939_bases
ATGAAGCATTATTTAGCAATTGATATTGGTGGTACTGCTATCAAGTATGGCTTGATTTCTGAAACAGGAGACCTGTTGGA
AAAAGAGGAAATGGCCACTGAGGCTTATAAAGGTGGTCCCTCTATTTTGGAAAAGGTCAAGGGCTTGGTAAAGACCTATC
AAGACCAAATGGATCTGGCTGGAGTGGCCATTTCTTCTGCAGGAATGGTTAATCCTGATAAGGGAGAAATCTTTTATGCC
GGCCCTCAGATTCCTAACTATGCTGGAACTCAGTTTAAAAAAGAGATTGAAGAGACTTTCGGGTTACCGTGTGAAGTGGA
AAACGATGTTAACTGTGCTGGTCTAGCCGAAGCTATTTCTGGTAGTGCCAAGGATTATCCTGTGGCTCTTTGCTTGACAA
TTGGGACGGGAATCGGTGGCTGTTTATTGTTTAATTCCCAAGTTTTTCATGGTAGTAGTCATTCAGCTTGCGAAGTTGGT
TACCTTCATTTGTCAGATGGTCAGTTTCAGGATCTGGCATCTACCACAGCTCTTGTTCAAGAGGTGGCCTTAGCTTATGG
CGATGACATTAGCCAATGGGATGGTCGTCGTATTTTTGAGCAGGCTAAAGCGGGTGATGCGATTTGTATAGCAGCCATTA
GTAAGCAGGTGGATTACTTAGGACAAGGTATTGCTAATATCTGCTACGTTGTTAACCCAAATGTGGTGGTGCTTGGTGGA
GGAATCATGGCGCAAAAAGACTATTTAGCTGATAAATTAAAGACAGCTCTTGATAGCTACTTGGTTTCTAGTCTTGCCAA
GAAAACTCAGCTGAAGTTTGCTAGTCATGGAAATAATGCTGGTATATTAGGAGCTTACTACCATTTTAAACAAAAGAATG
AGCGATCTTGTTCATTTATAACTCTTGAGAAAATCGAAAATAATTTAGCGAGTAGCTAA

Upstream 100 bases:

>100_bases
AGCTGAGTTGGTCGAGGAAGATAGGGTTATTTGCCAACGGGCTGCTGCTCTGATTAATCAGGCTAAGGAAACCTTTTAAT
AAGATGCGAGGGGATAACAA

Downstream 100 bases:

>100_bases
TCTTAGTGGCTGTGAGTCTATATGACGTGAAGAGTTCTTGTTTAAGTATACTGGGGGAGGTGAATGACGACCCTTTAAAA
AGAAAACAACGCCCTTTTTG

Product: N-acetylmannosamine kinase / transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MKHYLAIDIGGTAIKYGLISETGDLLEKEEMATEAYKGGPSILEKVKGLVKTYQDQMDLAGVAISSAGMVNPDKGEIFYA
GPQIPNYAGTQFKKEIEETFGLPCEVENDVNCAGLAEAISGSAKDYPVALCLTIGTGIGGCLLFNSQVFHGSSHSACEVG
YLHLSDGQFQDLASTTALVQEVALAYGDDISQWDGRRIFEQAKAGDAICIAAISKQVDYLGQGIANICYVVNPNVVVLGG
GIMAQKDYLADKLKTALDSYLVSSLAKKTQLKFASHGNNAGILGAYYHFKQKNERSCSFITLEKIENNLASS

Sequences:

>Translated_312_residues
MKHYLAIDIGGTAIKYGLISETGDLLEKEEMATEAYKGGPSILEKVKGLVKTYQDQMDLAGVAISSAGMVNPDKGEIFYA
GPQIPNYAGTQFKKEIEETFGLPCEVENDVNCAGLAEAISGSAKDYPVALCLTIGTGIGGCLLFNSQVFHGSSHSACEVG
YLHLSDGQFQDLASTTALVQEVALAYGDDISQWDGRRIFEQAKAGDAICIAAISKQVDYLGQGIANICYVVNPNVVVLGG
GIMAQKDYLADKLKTALDSYLVSSLAKKTQLKFASHGNNAGILGAYYHFKQKNERSCSFITLEKIENNLASS
>Mature_312_residues
MKHYLAIDIGGTAIKYGLISETGDLLEKEEMATEAYKGGPSILEKVKGLVKTYQDQMDLAGVAISSAGMVNPDKGEIFYA
GPQIPNYAGTQFKKEIEETFGLPCEVENDVNCAGLAEAISGSAKDYPVALCLTIGTGIGGCLLFNSQVFHGSSHSACEVG
YLHLSDGQFQDLASTTALVQEVALAYGDDISQWDGRRIFEQAKAGDAICIAAISKQVDYLGQGIANICYVVNPNVVVLGG
GIMAQKDYLADKLKTALDSYLVSSLAKKTQLKFASHGNNAGILGAYYHFKQKNERSCSFITLEKIENNLASS

Specific function: Unknown

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI190014632, Length=260, Percent_Identity=28.0769230769231, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI298566315, Length=260, Percent_Identity=28.0769230769231, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI4885285, Length=260, Percent_Identity=28.0769230769231, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI298566325, Length=260, Percent_Identity=28.0769230769231, Blast_Score=90, Evalue=3e-18,
Organism=Escherichia coli, GI1787363, Length=305, Percent_Identity=25.9016393442623, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI87081733, Length=310, Percent_Identity=22.5806451612903, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786891, Length=270, Percent_Identity=21.8518518518519, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 33338; Mature: 33338

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHYLAIDIGGTAIKYGLISETGDLLEKEEMATEAYKGGPSILEKVKGLVKTYQDQMDLA
CCEEEEEEECCCEEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
GVAISSAGMVNPDKGEIFYAGPQIPNYAGTQFKKEIEETFGLPCEVENDVNCAGLAEAIS
HEEECCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCEECCCCCCHHHHHHHHC
GSAKDYPVALCLTIGTGIGGCLLFNSQVFHGSSHSACEVGYLHLSDGQFQDLASTTALVQ
CCCCCCCEEEEEEECCCCCEEEEECCEEECCCCCCCEEEEEEEECCCCHHHHHHHHHHHH
EVALAYGDDISQWDGRRIFEQAKAGDAICIAAISKQVDYLGQGIANICYVVNPNVVVLGG
HHHHHHCCCCHHCCHHHHHHHHCCCCEEEEHHHHHHHHHHHCCHHHEEEEECCCEEEEEC
GIMAQKDYLADKLKTALDSYLVSSLAKKTQLKFASHGNNAGILGAYYHFKQKNERSCSFI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHCCCCCCCCCEE
TLEKIENNLASS
EHHHHHHHHCCC
>Mature Secondary Structure
MKHYLAIDIGGTAIKYGLISETGDLLEKEEMATEAYKGGPSILEKVKGLVKTYQDQMDLA
CCEEEEEEECCCEEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
GVAISSAGMVNPDKGEIFYAGPQIPNYAGTQFKKEIEETFGLPCEVENDVNCAGLAEAIS
HEEECCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCCEECCCCCCHHHHHHHHC
GSAKDYPVALCLTIGTGIGGCLLFNSQVFHGSSHSACEVGYLHLSDGQFQDLASTTALVQ
CCCCCCCEEEEEEECCCCCEEEEECCEEECCCCCCCEEEEEEEECCCCHHHHHHHHHHHH
EVALAYGDDISQWDGRRIFEQAKAGDAICIAAISKQVDYLGQGIANICYVVNPNVVVLGG
HHHHHHCCCCHHCCHHHHHHHHCCCCEEEEHHHHHHHHHHHCCHHHEEEEECCCEEEEEC
GIMAQKDYLADKLKTALDSYLVSSLAKKTQLKFASHGNNAGILGAYYHFKQKNERSCSFI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHCCCCCCCCCEE
TLEKIENNLASS
EHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11792842; 8177218 [H]