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The map label for this gene is ycbL [H]

Identifier: 94986360

GI number: 94986360

Start: 2386668

End: 2387327

Strand: Reverse

Name: ycbL [H]

Synonym: Dgeo_2261

Alternate gene names: 94986360

Gene position: 2387327-2386668 (Counterclockwise)

Preceding gene: 94986361

Following gene: 94986359

Centisome position: 96.76

GC content: 69.7

Gene sequence:

>660_bases
ATGATCAAGCCGAGACAACACGGCGCGGCGCGGGTGTGGGTCCTGCCGACCGGGCCGCTTCAGGAAAACGCGCTGCTGGT
GGCGGGGCAGGCGGGTGAGGGCTTCCTCGTCGACCCCGGCGACGACGCCGAGCAGGTACTGGCCCTGGTGCGCGACTCGG
GCGTGAAGGTACGGGGGATCTTGCTGACGCACGCGCACTTTGACCACATTGGCGCGGTGCAGCCGGTGCGGGAGGCGCTG
GCTGTGCCGGTGTACCTCCACCCTGCCGACCTGTCGATCTACCAGCAGGGCGAGGCCTCAGCGGCCCGTTGGGGTCTGCC
CTTTACCCAGCCGGAGGCGCCCGACGTGGAGATCGCGCAGGGGCAGACGTTCACAGCGGGGGATCTGAGGCTAACGGCCC
GCGAGTTGCCGGGGCACGCGCCCGGGCATGTGGTCTTTGTGGCTCAGAGCGGAGAGGAGCCGGGGTTCGTGGTGGCGGGC
GACACCCTCTTCCAGGGAAGCATCGGGCGCACCGACCTGCCGGGCGGGAACCACCCCCAGCTCATCGCGGGCATCCGGCG
CGAGCTGCTGAGCTTGCCCGACGAGACAGCGATCTACCCGGGGCATGGTCCTGCGACCACCGTTGGAGCCGAGCGGCGCA
CCAACCTTTTTTTGCGCTGA

Upstream 100 bases:

>100_bases
CCCGAGCCTCAGTTTTCAGGTGTTCGCCCTGAACCTGCGGGAGGCGTTCGGGGAGGGGTGAGGGGTCGCTCCTTGCTCTG
CTCCGTCCTAGACTCACGCC

Downstream 100 bases:

>100_bases
ACCAGGGGATGGACTGATGAAGGCTGACCCGAGAGAGCTGATTCGCGCGGAGGTGGGCTGATGCCGGGGGTGGGCAGCGG
GCCGGGCGCCGTGCTCGACC

Product: beta-lactamase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MIKPRQHGAARVWVLPTGPLQENALLVAGQAGEGFLVDPGDDAEQVLALVRDSGVKVRGILLTHAHFDHIGAVQPVREAL
AVPVYLHPADLSIYQQGEASAARWGLPFTQPEAPDVEIAQGQTFTAGDLRLTARELPGHAPGHVVFVAQSGEEPGFVVAG
DTLFQGSIGRTDLPGGNHPQLIAGIRRELLSLPDETAIYPGHGPATTVGAERRTNLFLR

Sequences:

>Translated_219_residues
MIKPRQHGAARVWVLPTGPLQENALLVAGQAGEGFLVDPGDDAEQVLALVRDSGVKVRGILLTHAHFDHIGAVQPVREAL
AVPVYLHPADLSIYQQGEASAARWGLPFTQPEAPDVEIAQGQTFTAGDLRLTARELPGHAPGHVVFVAQSGEEPGFVVAG
DTLFQGSIGRTDLPGGNHPQLIAGIRRELLSLPDETAIYPGHGPATTVGAERRTNLFLR
>Mature_219_residues
MIKPRQHGAARVWVLPTGPLQENALLVAGQAGEGFLVDPGDDAEQVLALVRDSGVKVRGILLTHAHFDHIGAVQPVREAL
AVPVYLHPADLSIYQQGEASAARWGLPFTQPEAPDVEIAQGQTFTAGDLRLTARELPGHAPGHVVFVAQSGEEPGFVVAG
DTLFQGSIGRTDLPGGNHPQLIAGIRRELLSLPDETAIYPGHGPATTVGAERRTNLFLR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI21703352, Length=204, Percent_Identity=28.4313725490196, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI116642887, Length=204, Percent_Identity=28.4313725490196, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787158, Length=208, Percent_Identity=38.9423076923077, Blast_Score=149, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17538952, Length=191, Percent_Identity=26.7015706806283, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356335, Length=193, Percent_Identity=30.5699481865285, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24667711, Length=193, Percent_Identity=30.5699481865285, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24667703, Length=193, Percent_Identity=30.5699481865285, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 23252; Mature: 23252

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKPRQHGAARVWVLPTGPLQENALLVAGQAGEGFLVDPGDDAEQVLALVRDSGVKVRGI
CCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCEEECCCCCHHHHHHHHHCCCCEEEEE
LLTHAHFDHIGAVQPVREALAVPVYLHPADLSIYQQGEASAARWGLPFTQPEAPDVEIAQ
EEEECCCCCCCCHHHHHHHHCCCEEEECCCCEEEECCCCCHHHCCCCCCCCCCCCEEEEC
GQTFTAGDLRLTARELPGHAPGHVVFVAQSGEEPGFVVAGDTLFQGSIGRTDLPGGNHPQ
CCEEECCCEEEEHHHCCCCCCCEEEEEEECCCCCCEEEECCEEEECCCCCCCCCCCCCHH
LIAGIRRELLSLPDETAIYPGHGPATTVGAERRTNLFLR
HHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCEECC
>Mature Secondary Structure
MIKPRQHGAARVWVLPTGPLQENALLVAGQAGEGFLVDPGDDAEQVLALVRDSGVKVRGI
CCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCEEECCCCCHHHHHHHHHCCCCEEEEE
LLTHAHFDHIGAVQPVREALAVPVYLHPADLSIYQQGEASAARWGLPFTQPEAPDVEIAQ
EEEECCCCCCCCHHHHHHHHCCCEEEECCCCEEEECCCCCHHHCCCCCCCCCCCCEEEEC
GQTFTAGDLRLTARELPGHAPGHVVFVAQSGEEPGFVVAGDTLFQGSIGRTDLPGGNHPQ
CCEEECCCEEEEHHHCCCCCCCEEEEEEECCCCCCEEEECCEEEECCCCCCCCCCCCCHH
LIAGIRRELLSLPDETAIYPGHGPATTVGAERRTNLFLR
HHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]