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The map label for this gene is citZ [H]

Identifier: 94986344

GI number: 94986344

Start: 2369011

End: 2370219

Strand: Reverse

Name: citZ [H]

Synonym: Dgeo_2245

Alternate gene names: 94986344

Gene position: 2370219-2369011 (Counterclockwise)

Preceding gene: 162139470

Following gene: 94986342

Centisome position: 96.07

GC content: 75.02

Gene sequence:

>1209_bases
GTGACGGCTCGGACCCTGACGACCGCCGAGGCGATCGCCCTACTGGGGGTGAAGCCCGCTACGCTCTATGCCTACGTGTC
GCGCGGCCTGATTCGCAGCGAGCCCGGCCCGCCCGGCACACGTGAGCGGCGCTATCACGCGGAGGATGTCCAGAAGCTGG
TGCGGCGCCGGGGGGTGCGGCGCGATCCTGAAGCCGCTACTGAGGAAGCGGTGCAGGAGGCGCTGGCCTGGGGAACGCCG
GTGCTGGACAGCGCGCTGACCCGGATCGCCGAGGGCACGCTGAGTTACCGCGGTCGGGACGCCGTGGAGCTGGCCGAAAC
CGCCACGGTGGAGGAGGTGGCGGCGCTGCTGTGGACCGGCGCGGCAGACGGCTGGACGAGGCTCCCGCTGCGAGCCCGGT
TGACCCTGGCGCCGCTGCCCCGAGCTGAGAGTGCGCTGGAGGCGCTGGGTTTCGCGCTGGTGCACGCGGGGGCGCACGAC
CTCGCCGCCCTGGATGCCCGGCCCGAGGCCCTGCCCACGGCGGCGGCCCGGGTACTGAGTCTGCTCTACGGCACGCTGGA
GCGCCATCTCGGCGTGCCGCCGGCCCCCGACCTGCCGCTGCATGCTCGTCTGGCCCGCGCGTGGCAGACTGACGCGCCGG
GGGCCGACCTGCTGCGCCGGGCGTTGGTGCTGCTGGCCGACCACGAGCTCAATGTCAGTGCCTTTACGGCCCGGGTGGCG
GCGGGCGGGGGAGCCAGCCTACCCCACACCACCCTGGCGGCGCTGGCCGCCCTGCAGGGGCCGCGGCATGGGCTGGCGGG
TGCGGCCGCGTATGACCTCGTGCGGCAGGCGCTGGAGGGTGACGCCGGGGCTGCCCTGCGCGAGACCCTGCGCCTCCAGG
CCCATCCGCCCGGCTTCGGGCACCGGCTCTATCCTGGGGGGGATCCACGGGCCCGGGCACTGCTCGCGGCGTTGCAGGCG
GCGCGGCCCAAGGCGCCCGCCGTGCAGGCTGTCCGCGCCCTGGCTGAGCGGATGCGGGAGGAGACGGGCGAAGCCCCCAA
TCTTGATCTGGCCCTCGCCGCGCTGGTCCATGCGCTCGGCCGTGCTGCTGAGGACACCGTCGCGCTGTTTGCGCTGGGGC
GCAGCTCGGGCTGGCTGGCCCACGCGATCGAGGCGCGCATGGGGGGGCGGTTCATCCGGCCCCGTGCGCGCTACGTCGGC
CCGCCGTGA

Upstream 100 bases:

>100_bases
GCCACATCAGCTACGGTGGAGAACGTTGTCATGGCTGCACGCTAGTCCGGTCTATCTATATCGTCAATCTTGATGAAAGA
ATCAATGTTAGAGTGGAAGA

Downstream 100 bases:

>100_bases
CTATGCGGCTGTCCGGCGTTTTTCCCGCACCAGGGCAAAGGCTCGGCCACCCAGCACCGCCACCAGAGCTGCACCGAGCA
GGGCGATGCCCAGCGCTGCG

Product: citrate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MTARTLTTAEAIALLGVKPATLYAYVSRGLIRSEPGPPGTRERRYHAEDVQKLVRRRGVRRDPEAATEEAVQEALAWGTP
VLDSALTRIAEGTLSYRGRDAVELAETATVEEVAALLWTGAADGWTRLPLRARLTLAPLPRAESALEALGFALVHAGAHD
LAALDARPEALPTAAARVLSLLYGTLERHLGVPPAPDLPLHARLARAWQTDAPGADLLRRALVLLADHELNVSAFTARVA
AGGGASLPHTTLAALAALQGPRHGLAGAAAYDLVRQALEGDAGAALRETLRLQAHPPGFGHRLYPGGDPRARALLAALQA
ARPKAPAVQAVRALAERMREETGEAPNLDLALAALVHALGRAAEDTVALFALGRSSGWLAHAIEARMGGRFIRPRARYVG
PP

Sequences:

>Translated_402_residues
MTARTLTTAEAIALLGVKPATLYAYVSRGLIRSEPGPPGTRERRYHAEDVQKLVRRRGVRRDPEAATEEAVQEALAWGTP
VLDSALTRIAEGTLSYRGRDAVELAETATVEEVAALLWTGAADGWTRLPLRARLTLAPLPRAESALEALGFALVHAGAHD
LAALDARPEALPTAAARVLSLLYGTLERHLGVPPAPDLPLHARLARAWQTDAPGADLLRRALVLLADHELNVSAFTARVA
AGGGASLPHTTLAALAALQGPRHGLAGAAAYDLVRQALEGDAGAALRETLRLQAHPPGFGHRLYPGGDPRARALLAALQA
ARPKAPAVQAVRALAERMREETGEAPNLDLALAALVHALGRAAEDTVALFALGRSSGWLAHAIEARMGGRFIRPRARYVG
PP
>Mature_401_residues
TARTLTTAEAIALLGVKPATLYAYVSRGLIRSEPGPPGTRERRYHAEDVQKLVRRRGVRRDPEAATEEAVQEALAWGTPV
LDSALTRIAEGTLSYRGRDAVELAETATVEEVAALLWTGAADGWTRLPLRARLTLAPLPRAESALEALGFALVHAGAHDL
AALDARPEALPTAAARVLSLLYGTLERHLGVPPAPDLPLHARLARAWQTDAPGADLLRRALVLLADHELNVSAFTARVAA
GGGASLPHTTLAALAALQGPRHGLAGAAAYDLVRQALEGDAGAALRETLRLQAHPPGFGHRLYPGGDPRARALLAALQAA
RPKAPAVQAVRALAERMREETGEAPNLDLALAALVHALGRAAEDTVALFALGRSSGWLAHAIEARMGGRFIRPRARYVGP
P

Specific function: Catalyzes The Synthesis Of 2-Methylcitrate From Propionyl-CoA And Oxaloacetate. Also Catalyzes The Condensation Of Oxaloacetate With Acetyl-CoA But With A Lower Specificity. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786527, Length=358, Percent_Identity=30.4469273743017, Blast_Score=121, Evalue=9e-29,
Organism=Escherichia coli, GI1786939, Length=207, Percent_Identity=30.4347826086957, Blast_Score=78, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011278
- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 42457; Mature: 42326

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARTLTTAEAIALLGVKPATLYAYVSRGLIRSEPGPPGTRERRYHAEDVQKLVRRRGVR
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
RDPEAATEEAVQEALAWGTPVLDSALTRIAEGTLSYRGRDAVELAETATVEEVAALLWTG
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
AADGWTRLPLRARLTLAPLPRAESALEALGFALVHAGAHDLAALDARPEALPTAAARVLS
CCCCCEECCCEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHH
LLYGTLERHLGVPPAPDLPLHARLARAWQTDAPGADLLRRALVLLADHELNVSAFTARVA
HHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
AGGGASLPHTTLAALAALQGPRHGLAGAAAYDLVRQALEGDAGAALRETLRLQAHPPGFG
CCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCC
HRLYPGGDPRARALLAALQAARPKAPAVQAVRALAERMREETGEAPNLDLALAALVHALG
CCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHC
RAAEDTVALFALGRSSGWLAHAIEARMGGRFIRPRARYVGPP
CCHHHHEEEEEECCCCCHHHHHHHHHHCCCEECCCCCCCCCC
>Mature Secondary Structure 
TARTLTTAEAIALLGVKPATLYAYVSRGLIRSEPGPPGTRERRYHAEDVQKLVRRRGVR
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
RDPEAATEEAVQEALAWGTPVLDSALTRIAEGTLSYRGRDAVELAETATVEEVAALLWTG
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
AADGWTRLPLRARLTLAPLPRAESALEALGFALVHAGAHDLAALDARPEALPTAAARVLS
CCCCCEECCCEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHH
LLYGTLERHLGVPPAPDLPLHARLARAWQTDAPGADLLRRALVLLADHELNVSAFTARVA
HHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
AGGGASLPHTTLAALAALQGPRHGLAGAAAYDLVRQALEGDAGAALRETLRLQAHPPGFG
CCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCC
HRLYPGGDPRARALLAALQAARPKAPAVQAVRALAERMREETGEAPNLDLALAALVHALG
CCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHC
RAAEDTVALFALGRSSGWLAHAIEARMGGRFIRPRARYVGPP
CCHHHHEEEEEECCCCCHHHHHHHHHHCCCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9006016; 12397186 [H]