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The map label for this gene is galE [H]

Identifier: 94986341

GI number: 94986341

Start: 2365653

End: 2366657

Strand: Reverse

Name: galE [H]

Synonym: Dgeo_2242

Alternate gene names: 94986341

Gene position: 2366657-2365653 (Counterclockwise)

Preceding gene: 94986342

Following gene: 94986339

Centisome position: 95.92

GC content: 65.77

Gene sequence:

>1005_bases
ATGAAGCTGATGGTGGTGGGAGGGGCTGGCTACATCGGGTCGCATACCGTGCGGCAGCTGCGGCAGGCCGGATACGAGGT
GGTGGTGTTCGACAACCTGTCGAGCGGGCATGCGGCGGCCCTGCCGCCCGAGGTGCCGCTGGTGCGCGGTGATCTGCTCG
ACCTGGAGGCGGTGAAGGGGGCACTGGAGGCGCACAAGCCCGATGCGGTGATTCATTTCGCCGCGCTGATCGAGGTCGGC
GAGAGTATGCGGGCGCCGGGGCGCTACTACCGCAACAACGTGGTGGGCAGCCTGAACCTGTTACAGGCCATCGTGAAGAC
ACGCAAGGTGCCGCTGGTCTTCAGTTCGACTGCCGCCGTCTACGGCACCACCGATGCTGTGCCGATCCCCGAGGACGCGC
CGCTCCACCCCGAGAGTGTCTACGGCGAAACGAAGCTGATGACAGAGCGCATGATCCACGCCTTCCATGTGGCGCACGGC
CTACCCTACATCATCCTGCGGTACTTCAACGTGTGCGGCGCGGCCCCGGATGGCCAGATCGGGGAGGCCCATCCCCACAA
GACGCACCTGATCGAACTGGCCTGCCTGACCGCCCTGGGCCAGCGCGAGCAGATGATGATCTTCGGTGCTGACTATCCCA
CCCCCGACGGCACCTGCATCCGCGATTACATCCACGTGCTCGACCTGGCCGACGCGCACGTCCTGGCTGTGCAGGCTCTG
GCACAAGGCCAGCGGGACGCCGCCACCTACAATGTTGGCCTGGGCTACGGCTTCAGTGTGCTGCAGGTGCTTGACGCGGT
GGACGCGGTGATTGCTGAAGACGGCCTCCCGCCCCTGAAACGCGAGATTGCCCCCCGCCGCCCCGGTGATCCCCCACGGT
TGGTTGCGGATGCCCGCCGCATCGTGGAGGAGCTGGGGTTCAAGCCGCAGTTGACTGAGCTCAAGGAGATCGTGCGGACA
GCCTGGGAATGGCACCGGAAACATCCGCAGGGGTATGAGGCCTAG

Upstream 100 bases:

>100_bases
GTGACGCTGCCGACCCGCTTGGTGGTGCGAGGGAGCAGCGGCGCCCCCTAAAGGAATCCTTTGGCGCCCCGCGGCCGTTC
CATCGCTTACCCTGTCTTTC

Downstream 100 bases:

>100_bases
GGCAGCGCTGTTGTCGCTTGTGGTGTTGGCGCTGCCGAGATGGCTCCCGCCCAGGTCGGCAGGTTTGGGGGCTGCCAGGA
GCTCAAGCTCAGGCGGCCCC

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MKLMVVGGAGYIGSHTVRQLRQAGYEVVVFDNLSSGHAAALPPEVPLVRGDLLDLEAVKGALEAHKPDAVIHFAALIEVG
ESMRAPGRYYRNNVVGSLNLLQAIVKTRKVPLVFSSTAAVYGTTDAVPIPEDAPLHPESVYGETKLMTERMIHAFHVAHG
LPYIILRYFNVCGAAPDGQIGEAHPHKTHLIELACLTALGQREQMMIFGADYPTPDGTCIRDYIHVLDLADAHVLAVQAL
AQGQRDAATYNVGLGYGFSVLQVLDAVDAVIAEDGLPPLKREIAPRRPGDPPRLVADARRIVEELGFKPQLTELKEIVRT
AWEWHRKHPQGYEA

Sequences:

>Translated_334_residues
MKLMVVGGAGYIGSHTVRQLRQAGYEVVVFDNLSSGHAAALPPEVPLVRGDLLDLEAVKGALEAHKPDAVIHFAALIEVG
ESMRAPGRYYRNNVVGSLNLLQAIVKTRKVPLVFSSTAAVYGTTDAVPIPEDAPLHPESVYGETKLMTERMIHAFHVAHG
LPYIILRYFNVCGAAPDGQIGEAHPHKTHLIELACLTALGQREQMMIFGADYPTPDGTCIRDYIHVLDLADAHVLAVQAL
AQGQRDAATYNVGLGYGFSVLQVLDAVDAVIAEDGLPPLKREIAPRRPGDPPRLVADARRIVEELGFKPQLTELKEIVRT
AWEWHRKHPQGYEA
>Mature_334_residues
MKLMVVGGAGYIGSHTVRQLRQAGYEVVVFDNLSSGHAAALPPEVPLVRGDLLDLEAVKGALEAHKPDAVIHFAALIEVG
ESMRAPGRYYRNNVVGSLNLLQAIVKTRKVPLVFSSTAAVYGTTDAVPIPEDAPLHPESVYGETKLMTERMIHAFHVAHG
LPYIILRYFNVCGAAPDGQIGEAHPHKTHLIELACLTALGQREQMMIFGADYPTPDGTCIRDYIHVLDLADAHVLAVQAL
AQGQRDAATYNVGLGYGFSVLQVLDAVDAVIAEDGLPPLKREIAPRRPGDPPRLVADARRIVEELGFKPQLTELKEIVRT
AWEWHRKHPQGYEA

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=349, Percent_Identity=37.8223495702006, Blast_Score=199, Evalue=3e-51,
Organism=Homo sapiens, GI56118217, Length=349, Percent_Identity=37.8223495702006, Blast_Score=199, Evalue=3e-51,
Organism=Homo sapiens, GI189083684, Length=349, Percent_Identity=37.8223495702006, Blast_Score=199, Evalue=3e-51,
Organism=Homo sapiens, GI7657641, Length=345, Percent_Identity=23.768115942029, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI42516563, Length=332, Percent_Identity=23.4939759036145, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1786974, Length=343, Percent_Identity=40.8163265306122, Blast_Score=241, Evalue=6e-65,
Organism=Escherichia coli, GI48994969, Length=361, Percent_Identity=28.808864265928, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788353, Length=357, Percent_Identity=29.6918767507003, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1790049, Length=272, Percent_Identity=26.8382352941176, Blast_Score=71, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71982035, Length=355, Percent_Identity=37.7464788732394, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI71982038, Length=357, Percent_Identity=37.5350140056022, Blast_Score=205, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17539532, Length=322, Percent_Identity=24.8447204968944, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17568069, Length=332, Percent_Identity=25, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI115532424, Length=326, Percent_Identity=23.6196319018405, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=350, Percent_Identity=37.4285714285714, Blast_Score=218, Evalue=1e-57,
Organism=Drosophila melanogaster, GI19923002, Length=347, Percent_Identity=36.3112391930836, Blast_Score=213, Evalue=1e-55,
Organism=Drosophila melanogaster, GI21356223, Length=315, Percent_Identity=23.1746031746032, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36443; Mature: 36443

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLMVVGGAGYIGSHTVRQLRQAGYEVVVFDNLSSGHAAALPPEVPLVRGDLLDLEAVKG
CEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEECCCCHHHHHHHH
ALEAHKPDAVIHFAALIEVGESMRAPGRYYRNNVVGSLNLLQAIVKTRKVPLVFSSTAAV
HHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHCCCCEEEECCEEE
YGTTDAVPIPEDAPLHPESVYGETKLMTERMIHAFHVAHGLPYIILRYFNVCGAAPDGQI
EECCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCC
GEAHPHKTHLIELACLTALGQREQMMIFGADYPTPDGTCIRDYIHVLDLADAHVLAVQAL
CCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHH
AQGQRDAATYNVGLGYGFSVLQVLDAVDAVIAEDGLPPLKREIAPRRPGDPPRLVADARR
HCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHH
IVEELGFKPQLTELKEIVRTAWEWHRKHPQGYEA
HHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKLMVVGGAGYIGSHTVRQLRQAGYEVVVFDNLSSGHAAALPPEVPLVRGDLLDLEAVKG
CEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEECCCCHHHHHHHH
ALEAHKPDAVIHFAALIEVGESMRAPGRYYRNNVVGSLNLLQAIVKTRKVPLVFSSTAAV
HHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHCCCCEEEECCEEE
YGTTDAVPIPEDAPLHPESVYGETKLMTERMIHAFHVAHGLPYIILRYFNVCGAAPDGQI
EECCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCC
GEAHPHKTHLIELACLTALGQREQMMIFGADYPTPDGTCIRDYIHVLDLADAHVLAVQAL
CCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHH
AQGQRDAATYNVGLGYGFSVLQVLDAVDAVIAEDGLPPLKREIAPRRPGDPPRLVADARR
HCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHH
IVEELGFKPQLTELKEIVRTAWEWHRKHPQGYEA
HHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]