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The map label for this gene is adrA [H]

Identifier: 94986328

GI number: 94986328

Start: 2349085

End: 2349690

Strand: Reverse

Name: adrA [H]

Synonym: Dgeo_2229

Alternate gene names: 94986328

Gene position: 2349690-2349085 (Counterclockwise)

Preceding gene: 94986331

Following gene: 94986327

Centisome position: 95.24

GC content: 67.99

Gene sequence:

>606_bases
ATGCCCCGTCCCAACATCCTCACCCGACCCGCCTTTGAGGAGGCCTTCGAGGCCCTGAACGGCGCCCCGGTGACGCTGGC
CGTCCTCGACCTCGACCATTTCAAGCGGCTCAATGACACCTTGGGCCATGCTGAGGGGGACCGGGTGCTGCGCGGCGTTG
AGAGGCTGCTCTCCGAGAGTCTGCCCAGCGGCAGCATCGTCGGACGGCTGGGAGGGGATGAGTACGCCGTCCTGCTGCCC
GAGACCGCTGCCGAGACGGCCCTGATCCTCTTTGACGAGGTGATCAAGCACTTCCATATCCACCGCGACCCCCATTGGCC
GCGTACCCTGGGCCTGAGCGTGGGGCTGGCGGCCCGGCCCGCCCACGCCCACACCTTCGCTGACCTGTACCGCGCCGCGG
ACGAGGCGCTGCTGCGGGCCAAGCGTGAGGGCCGCTCACGGGCGTGCATCTACGTGGAGGGCAAGATGGTGCTGAAGAGC
AACTATTACCCCAGGAGCCAGCTCGAACGCCTCGCCAAGCTGTCGGGGGCACTGGGCCGGACGGAGGCGAGCCTGTTGCG
GGAAGCGCTGGACGAGCTGATTGAGCGGTACCGGGAGGCGCTGTAA

Upstream 100 bases:

>100_bases
GCCCCTGGCATTGCCGTAATAGTCCTGATATATATATATAATTCCTATATATAGAAATTGCGAGCTGACCTTTTTCTGAT
CCTGGAGAGGAGAACCCGCT

Downstream 100 bases:

>100_bases
TGCGGGAGCGGGAAACGGTGCGTGGCCCGTGGTGGTTGGCCTTCGCCCTGGTCCATGGCCATCAAGACCTGAGATGATCG
CTCAGACGCTCCACCTTACC

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MPRPNILTRPAFEEAFEALNGAPVTLAVLDLDHFKRLNDTLGHAEGDRVLRGVERLLSESLPSGSIVGRLGGDEYAVLLP
ETAAETALILFDEVIKHFHIHRDPHWPRTLGLSVGLAARPAHAHTFADLYRAADEALLRAKREGRSRACIYVEGKMVLKS
NYYPRSQLERLAKLSGALGRTEASLLREALDELIERYREAL

Sequences:

>Translated_201_residues
MPRPNILTRPAFEEAFEALNGAPVTLAVLDLDHFKRLNDTLGHAEGDRVLRGVERLLSESLPSGSIVGRLGGDEYAVLLP
ETAAETALILFDEVIKHFHIHRDPHWPRTLGLSVGLAARPAHAHTFADLYRAADEALLRAKREGRSRACIYVEGKMVLKS
NYYPRSQLERLAKLSGALGRTEASLLREALDELIERYREAL
>Mature_200_residues
PRPNILTRPAFEEAFEALNGAPVTLAVLDLDHFKRLNDTLGHAEGDRVLRGVERLLSESLPSGSIVGRLGGDEYAVLLPE
TAAETALILFDEVIKHFHIHRDPHWPRTLGLSVGLAARPAHAHTFADLYRAADEALLRAKREGRSRACIYVEGKMVLKSN
YYPRSQLERLAKLSGALGRTEASLLREALDELIERYREAL

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=125, Percent_Identity=38.4, Blast_Score=90, Evalue=8e-20,
Organism=Escherichia coli, GI1787262, Length=159, Percent_Identity=29.559748427673, Blast_Score=84, Evalue=5e-18,
Organism=Escherichia coli, GI1788381, Length=135, Percent_Identity=34.8148148148148, Blast_Score=77, Evalue=6e-16,
Organism=Escherichia coli, GI145693134, Length=151, Percent_Identity=32.4503311258278, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87081881, Length=124, Percent_Identity=35.4838709677419, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI87081974, Length=145, Percent_Identity=32.4137931034483, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1787056, Length=142, Percent_Identity=33.8028169014084, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1787541, Length=159, Percent_Identity=28.9308176100629, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1787802, Length=130, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87082007, Length=134, Percent_Identity=35.8208955223881, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788085, Length=156, Percent_Identity=27.5641025641026, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 22398; Mature: 22267

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPNILTRPAFEEAFEALNGAPVTLAVLDLDHFKRLNDTLGHAEGDRVLRGVERLLSES
CCCCCCCCCCCHHHHHHHHCCCCEEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
LPSGSIVGRLGGDEYAVLLPETAAETALILFDEVIKHFHIHRDPHWPRTLGLSVGLAARP
CCCCCEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCC
AHAHTFADLYRAADEALLRAKREGRSRACIYVEGKMVLKSNYYPRSQLERLAKLSGALGR
CHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECEEEEECCCCCHHHHHHHHHHHCCCCC
TEASLLREALDELIERYREAL
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PRPNILTRPAFEEAFEALNGAPVTLAVLDLDHFKRLNDTLGHAEGDRVLRGVERLLSES
CCCCCCCCCCHHHHHHHHCCCCEEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
LPSGSIVGRLGGDEYAVLLPETAAETALILFDEVIKHFHIHRDPHWPRTLGLSVGLAARP
CCCCCEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCC
AHAHTFADLYRAADEALLRAKREGRSRACIYVEGKMVLKSNYYPRSQLERLAKLSGALGR
CHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECEEEEECCCCCHHHHHHHHHHHCCCCC
TEASLLREALDELIERYREAL
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]