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The map label for this gene is yggV [C]

Identifier: 94986308

GI number: 94986308

Start: 2329902

End: 2330501

Strand: Reverse

Name: yggV [C]

Synonym: Dgeo_2209

Alternate gene names: 94986308

Gene position: 2330501-2329902 (Counterclockwise)

Preceding gene: 94986309

Following gene: 94986307

Centisome position: 94.46

GC content: 67.33

Gene sequence:

>600_bases
ATGCGGGTGGTCGTGGCGACCGGAAACGCCGGGAAGGTGCGCGAGATCGCAGAGGCGCTCTCGGAGTTGGGCTGGCAACT
GGAGGGCCTGAATGGTCTGACTCTCCCCGAGGAGACCGGGACCACCTACGAGGAGAACGCCGCCCTCAAGGCGTGTGCGG
CGGCGTTGGCAAAGGGCTTGCCCGCTCTGGCCGACGATTCCGGCCTGGAGGTGGCGGCCCTAGACGGGCAACCTGGGGTC
TACAGCGCCCGCTTTGGCAATCGCCCGAACGACACCGAGCGGAACCTCTACCTGCTGGAAAAACTGCGGGGCGTGCAGGA
CCGCCGGGCTAAATTCGTCTCGGTGGTGATGCTGGCCTATCCCGACGGTCACGTGGAAACCTACCGCGGCGAGCTGACCG
GCACGCTGCTGGAGGGTCCGCGCGGCGAGAACGGCTTCGGCTACGATCCCCTTTTTGTTCCTGACGGCGAGACCCGCACC
CTGGCCGAGATGACGGTGGCAGAAAAACGCACGATCAGCCACCGGGGGCGGGCGCTGGCGGCGCTGTTGGCGACGCACCG
AAATGGGCCGCCTCCCCGGGAAACGGTGCGCACAGAGTGA

Upstream 100 bases:

>100_bases
TCCCTCGCTCCCCCCCAAACGGCGTGACCCTCTCGCGCTGAGGCCGCGCCTCCCCTACACTCGGCGAGTGACGAGGAACG
CTGGAACAGGCGAGAACGGA

Downstream 100 bases:

>100_bases
AGATAAAGACCGGCAGCCCGCTGGGAAGCAGCCGGGTTGGCCGCTCGTGGTCAAGGGCGGACTGACGCTCCTAGAGGCTG
GGTCGAAGGCAAACCAAGTT

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MRVVVATGNAGKVREIAEALSELGWQLEGLNGLTLPEETGTTYEENAALKACAAALAKGLPALADDSGLEVAALDGQPGV
YSARFGNRPNDTERNLYLLEKLRGVQDRRAKFVSVVMLAYPDGHVETYRGELTGTLLEGPRGENGFGYDPLFVPDGETRT
LAEMTVAEKRTISHRGRALAALLATHRNGPPPRETVRTE

Sequences:

>Translated_199_residues
MRVVVATGNAGKVREIAEALSELGWQLEGLNGLTLPEETGTTYEENAALKACAAALAKGLPALADDSGLEVAALDGQPGV
YSARFGNRPNDTERNLYLLEKLRGVQDRRAKFVSVVMLAYPDGHVETYRGELTGTLLEGPRGENGFGYDPLFVPDGETRT
LAEMTVAEKRTISHRGRALAALLATHRNGPPPRETVRTE
>Mature_199_residues
MRVVVATGNAGKVREIAEALSELGWQLEGLNGLTLPEETGTTYEENAALKACAAALAKGLPALADDSGLEVAALDGQPGV
YSARFGNRPNDTERNLYLLEKLRGVQDRRAKFVSVVMLAYPDGHVETYRGELTGTLLEGPRGENGFGYDPLFVPDGETRT
LAEMTVAEKRTISHRGRALAALLATHRNGPPPRETVRTE

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family

Homologues:

Organism=Homo sapiens, GI15626999, Length=184, Percent_Identity=33.1521739130435, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI31657144, Length=153, Percent_Identity=34.640522875817, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1789324, Length=198, Percent_Identity=45.4545454545455, Blast_Score=141, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6322529, Length=188, Percent_Identity=30.3191489361702, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19920712, Length=186, Percent_Identity=34.4086021505376, Blast_Score=81, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPA_DEIGD (Q1IW81)

Other databases:

- EMBL:   CP000359
- RefSeq:   YP_605672.1
- ProteinModelPortal:   Q1IW81
- SMR:   Q1IW81
- STRING:   Q1IW81
- GeneID:   4056884
- GenomeReviews:   CP000359_GR
- KEGG:   dge:Dgeo_2209
- NMPDR:   fig|68909.1.peg.2760
- eggNOG:   COG0127
- HOGENOM:   HBG697237
- OMA:   TGVTFAE
- PhylomeDB:   Q1IW81
- ProtClustDB:   PRK00120
- BioCyc:   DGEO319795:DGEO_2209-MONOMER
- HAMAP:   MF_01405
- InterPro:   IPR002637
- InterPro:   IPR020922
- PANTHER:   PTHR11067
- TIGRFAMs:   TIGR00042

Pfam domain/function: PF01725 Ham1p_like

EC number: =3.6.1.15

Molecular weight: Translated: 21430; Mature: 21430

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVVVATGNAGKVREIAEALSELGWQLEGLNGLTLPEETGTTYEENAALKACAAALAKGL
CEEEEEECCCCHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
PALADDSGLEVAALDGQPGVYSARFGNRPNDTERNLYLLEKLRGVQDRRAKFVSVVMLAY
CCCCCCCCCEEEEECCCCCEEECCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHEEEEEEC
PDGHVETYRGELTGTLLEGPRGENGFGYDPLFVPDGETRTLAEMTVAEKRTISHRGRALA
CCCCCEEECCCEEEEEECCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
ALLATHRNGPPPRETVRTE
HHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MRVVVATGNAGKVREIAEALSELGWQLEGLNGLTLPEETGTTYEENAALKACAAALAKGL
CEEEEEECCCCHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
PALADDSGLEVAALDGQPGVYSARFGNRPNDTERNLYLLEKLRGVQDRRAKFVSVVMLAY
CCCCCCCCCEEEEECCCCCEEECCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHEEEEEEC
PDGHVETYRGELTGTLLEGPRGENGFGYDPLFVPDGETRTLAEMTVAEKRTISHRGRALA
CCCCCEEECCCEEEEEECCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
ALLATHRNGPPPRETVRTE
HHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA