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The map label for this gene is bpr [H]

Identifier: 94986180

GI number: 94986180

Start: 2190618

End: 2193164

Strand: Reverse

Name: bpr [H]

Synonym: Dgeo_2081

Alternate gene names: 94986180

Gene position: 2193164-2190618 (Counterclockwise)

Preceding gene: 94986181

Following gene: 94986179

Centisome position: 88.89

GC content: 66.39

Gene sequence:

>2547_bases
ATGAAGAGAACACAGGCAATCCTGCTCCTCGGCGCAGCGCTGACGCTGGGGAGCGCGACCCAAGCGAGCGCGGCGGGGCT
GTCGCGCTCGCTGTATGAAAAGGCGCTGCGCGGGGACAAGCAGACGGTGGGCGTCATTGTGCGTTTCAGCTTTCCGAACA
CCGCGCGGGGTCGGGCCCTCTTTAAGACTGCGCGGCAGCAGCTCAGTGCCCGCATCGCGCAGCTCGGCCCCGCCGCCGGA
TTTATCCAGCAGGCCCTCAACTCTGGCCGAGCGACCCAGCTGTGGCTCGACCAGAGCGTGTACCTGCCGATGACTCCGGC
GCAGGCGCAGGCCGTCTCGCTGCTGCCCTACGTGGATGCTGTCTTTGAGAACTTCAAGGTGCAGGTACCCAAGGCGGTGG
CTCTGAGTGCCGCTTCTGCTCCCGCCGGGACGCCCTGGCACCTCCAGAAGATCGGTGCGCCTCAGGCCTGGGCGGCCGGC
TTCCGCGGCCAGAATGTCCGGATCGGCCACCTCGACACCGGGATCGACCCCAACCACCCGGAACTCGCCGGGAAGCTGGC
GGCTTTCGCGGAGTTCAACGCGGAAGGTGACCGGGTGCAGAGCCAGCCCCACGACACCACCAACCACGGTACCCACACGG
CGGGCCTGCTGGTCGGTAAGGATGTCGGCGTGGCACCCCAAGCCAAACTCATCAGCGCGCTGGTGCTTCCCAACAACGAG
GGGACCTTCGCGCAGGTGATCGCCGGGATGCAGTACGTCCTCGATCCGGACAACAACGCCGATACCGACGACGGCGCCGA
CGTGGTGAACATGAGTCTGGGCATTCCCGGCACCTACAACGAGTTCATCGTGCCGGTGCAGAACATGCTCAAGGCGGGCG
TGGTGCCGGTCTTCGCCATCGGCAACTTTGGTCCCGGCAGCGCGACCACCGGCAGCCCCGGCAACCTCCCCGACGCGATC
GGCGTGGGCGCGGTGGACCAAAACGGGCAGGTCGCCAGCTTCAGCAGCCGCGGGCCGGTTGCTTGGCAGGGCCAGATCAA
CGGCGTCTTCGTGAAGCCCGACATCGCCGCGCCGGGGGTGAACATCACCAGCACTTTCCCGAACGGGCAGTACGGCGCTC
TGAGCGGGACCAGCCAGGCCAGCCCCATCGCGGCGGGCGCGGTGGCCCTCTTGCTGAGTGCCAAGCCCGGCAGCAGCGTA
GATGCGATCAAGAATGCTCTCTTCTCCAGCGCCAGCAACGCGGGCAGCAAGAACAACAACGTCGGCTACGGATTGATCAG
TGTGCCCGGCGCCCTCGCCAAGCTGGGTGTGAATGTGGGCGGCAGCCAGCCCACGCCGCAGCCGCAGCCACAACCCACTC
CCCAGCCGCAGCCCCAACCTCAACCTCAACCGCAGCCCCAACCTCAACCTCAACCGCAGCCCCAACCTCAACCGCAGCCC
ACGCCGCAGCCACAGCCTACCGGGCCTGCCGGGTATACGCTGTGCGCGGTGGAAGGCGGCACCTGCACCAACGTCGCCAA
CAAGCAGGTGGCCTTTGGGACGGCGGGGCGCTATGTCTACGGCACCAATGACGCCTCACCCAGCTTTAAGTGCACCGTGG
AGGAGTGGGGCGGCAATGATCCGGCCCGGGGTCAACTCAAGGGCTGCTTCGTCAAGAACTCGTCGGGGTCGCCCGCTCCA
GCACCTACCCCGGCGCCCGCGCCGCAGCCACCGAGCAGCGGGAAGAAACCCAGCGTGCTGCTGGTGGATGACGATATGGG
CCAGGGTGCAGACGTGACGAACGCGCTGCGCGACGCGATCAAGGCCAATGCGGCCAGCGGCGGCGCTTTTGTCTGGAACA
CCCAGACTCAGGGCGCGGTGCCGCTCGATCAGTTGCAGCGGGCCGACATCGTGATCTGGGCGACCGGTGAGCAGTACCAG
AACACCATCACGCCGCAGGATCAGAACACGCTGCGCCAGTACCTCGCGGGCGGGGGCCGTCTGCTGGTCACGGGGCAGGA
CGTGGGCTACGACATTGGGAACAGCGATTTCTACCGCAGCGTCCTGAAGACCCGTTTTGTGGCCGACAGCAGCGGCACGC
CCAAGTTCGTGACGCGCGGCGCTTTTGGCAACACCGCCTTTACCCTCAACGCGCAGGGCAGCGCTGGAAACCAGTACTAC
CCCGACGTGATCGCCGACCTGAACGGCTCGCAGGTGGTGGCTTCGTGGGGCAGCGCGAATGCGAATGCGGGCACCATCAC
CGCCCAGAGCATCCGAGTGGATCCCAACAAGAACCGCGCCCAGCAAAAGGTCGAGGATCCGCGCGGCCTGGTCGAGCGCT
TGGCGGCCAATGTGATCGGCTCCATTCTGAACCAGGTGCTGGGCGGCCAGCAGCCCACCCAGCGCCCGCGCGTCACCGCC
CAGAACGCGGGCGAGAATGCCGGAGCTATCGTGGTGAACGATGCCGGCAAGTACCGCACGGTGAACATGGGCTTTGGCCT
GGAAGGGCTCTCGCCCAACAGCCGCAATCTGCTGATCAAGACGAGCTTTGACTGGCTGATGCGATAA

Upstream 100 bases:

>100_bases
GCCTTCATCCCCAAAAGACTGACGCGCCCCTGACCTCAGCTCAAGGCATCCTCACCTGGTCTTCAGGGGACGTCACAGGC
GGCCCGTTAGGCTGCGGAGT

Downstream 100 bases:

>100_bases
GCAGTCAGGATTCAGAGGAGAGGGGAAGGGCCACAGGTGCGCGGCTTCCCCTCTCTCTGTCTGTCTTTAGCTCGTTCCTA
TCGAGAGAAAAGGTGGGCAG

Product: peptidase S8/S53 subtilisin kexin sedolisin

Products: NA

Alternate protein names: 90 kDa serine proteinase; Esterase; RP-I protease [H]

Number of amino acids: Translated: 848; Mature: 848

Protein sequence:

>848_residues
MKRTQAILLLGAALTLGSATQASAAGLSRSLYEKALRGDKQTVGVIVRFSFPNTARGRALFKTARQQLSARIAQLGPAAG
FIQQALNSGRATQLWLDQSVYLPMTPAQAQAVSLLPYVDAVFENFKVQVPKAVALSAASAPAGTPWHLQKIGAPQAWAAG
FRGQNVRIGHLDTGIDPNHPELAGKLAAFAEFNAEGDRVQSQPHDTTNHGTHTAGLLVGKDVGVAPQAKLISALVLPNNE
GTFAQVIAGMQYVLDPDNNADTDDGADVVNMSLGIPGTYNEFIVPVQNMLKAGVVPVFAIGNFGPGSATTGSPGNLPDAI
GVGAVDQNGQVASFSSRGPVAWQGQINGVFVKPDIAAPGVNITSTFPNGQYGALSGTSQASPIAAGAVALLLSAKPGSSV
DAIKNALFSSASNAGSKNNNVGYGLISVPGALAKLGVNVGGSQPTPQPQPQPTPQPQPQPQPQPQPQPQPQPQPQPQPQP
TPQPQPTGPAGYTLCAVEGGTCTNVANKQVAFGTAGRYVYGTNDASPSFKCTVEEWGGNDPARGQLKGCFVKNSSGSPAP
APTPAPAPQPPSSGKKPSVLLVDDDMGQGADVTNALRDAIKANAASGGAFVWNTQTQGAVPLDQLQRADIVIWATGEQYQ
NTITPQDQNTLRQYLAGGGRLLVTGQDVGYDIGNSDFYRSVLKTRFVADSSGTPKFVTRGAFGNTAFTLNAQGSAGNQYY
PDVIADLNGSQVVASWGSANANAGTITAQSIRVDPNKNRAQQKVEDPRGLVERLAANVIGSILNQVLGGQQPTQRPRVTA
QNAGENAGAIVVNDAGKYRTVNMGFGLEGLSPNSRNLLIKTSFDWLMR

Sequences:

>Translated_848_residues
MKRTQAILLLGAALTLGSATQASAAGLSRSLYEKALRGDKQTVGVIVRFSFPNTARGRALFKTARQQLSARIAQLGPAAG
FIQQALNSGRATQLWLDQSVYLPMTPAQAQAVSLLPYVDAVFENFKVQVPKAVALSAASAPAGTPWHLQKIGAPQAWAAG
FRGQNVRIGHLDTGIDPNHPELAGKLAAFAEFNAEGDRVQSQPHDTTNHGTHTAGLLVGKDVGVAPQAKLISALVLPNNE
GTFAQVIAGMQYVLDPDNNADTDDGADVVNMSLGIPGTYNEFIVPVQNMLKAGVVPVFAIGNFGPGSATTGSPGNLPDAI
GVGAVDQNGQVASFSSRGPVAWQGQINGVFVKPDIAAPGVNITSTFPNGQYGALSGTSQASPIAAGAVALLLSAKPGSSV
DAIKNALFSSASNAGSKNNNVGYGLISVPGALAKLGVNVGGSQPTPQPQPQPTPQPQPQPQPQPQPQPQPQPQPQPQPQP
TPQPQPTGPAGYTLCAVEGGTCTNVANKQVAFGTAGRYVYGTNDASPSFKCTVEEWGGNDPARGQLKGCFVKNSSGSPAP
APTPAPAPQPPSSGKKPSVLLVDDDMGQGADVTNALRDAIKANAASGGAFVWNTQTQGAVPLDQLQRADIVIWATGEQYQ
NTITPQDQNTLRQYLAGGGRLLVTGQDVGYDIGNSDFYRSVLKTRFVADSSGTPKFVTRGAFGNTAFTLNAQGSAGNQYY
PDVIADLNGSQVVASWGSANANAGTITAQSIRVDPNKNRAQQKVEDPRGLVERLAANVIGSILNQVLGGQQPTQRPRVTA
QNAGENAGAIVVNDAGKYRTVNMGFGLEGLSPNSRNLLIKTSFDWLMR
>Mature_848_residues
MKRTQAILLLGAALTLGSATQASAAGLSRSLYEKALRGDKQTVGVIVRFSFPNTARGRALFKTARQQLSARIAQLGPAAG
FIQQALNSGRATQLWLDQSVYLPMTPAQAQAVSLLPYVDAVFENFKVQVPKAVALSAASAPAGTPWHLQKIGAPQAWAAG
FRGQNVRIGHLDTGIDPNHPELAGKLAAFAEFNAEGDRVQSQPHDTTNHGTHTAGLLVGKDVGVAPQAKLISALVLPNNE
GTFAQVIAGMQYVLDPDNNADTDDGADVVNMSLGIPGTYNEFIVPVQNMLKAGVVPVFAIGNFGPGSATTGSPGNLPDAI
GVGAVDQNGQVASFSSRGPVAWQGQINGVFVKPDIAAPGVNITSTFPNGQYGALSGTSQASPIAAGAVALLLSAKPGSSV
DAIKNALFSSASNAGSKNNNVGYGLISVPGALAKLGVNVGGSQPTPQPQPQPTPQPQPQPQPQPQPQPQPQPQPQPQPQP
TPQPQPTGPAGYTLCAVEGGTCTNVANKQVAFGTAGRYVYGTNDASPSFKCTVEEWGGNDPARGQLKGCFVKNSSGSPAP
APTPAPAPQPPSSGKKPSVLLVDDDMGQGADVTNALRDAIKANAASGGAFVWNTQTQGAVPLDQLQRADIVIWATGEQYQ
NTITPQDQNTLRQYLAGGGRLLVTGQDVGYDIGNSDFYRSVLKTRFVADSSGTPKFVTRGAFGNTAFTLNAQGSAGNQYY
PDVIADLNGSQVVASWGSANANAGTITAQSIRVDPNKNRAQQKVEDPRGLVERLAANVIGSILNQVLGGQQPTQRPRVTA
QNAGENAGAIVVNDAGKYRTVNMGFGLEGLSPNSRNLLIKTSFDWLMR

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI4506775, Length=269, Percent_Identity=33.8289962825279, Blast_Score=116, Evalue=8e-26,
Organism=Homo sapiens, GI31317307, Length=306, Percent_Identity=29.4117647058824, Blast_Score=88, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6319893, Length=248, Percent_Identity=31.8548387096774, Blast_Score=94, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6324576, Length=286, Percent_Identity=29.7202797202797, Blast_Score=91, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6320775, Length=235, Percent_Identity=31.4893617021277, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI45550681, Length=250, Percent_Identity=29.2, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17137360, Length=266, Percent_Identity=32.3308270676692, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24653270, Length=266, Percent_Identity=32.3308270676692, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008969
- InterPro:   IPR014766
- InterPro:   IPR008985
- InterPro:   IPR012103
- InterPro:   IPR008757
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR010259 [H]

Pfam domain/function: PF05922 Inhibitor_I9; PF05547 Peptidase_M6; PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 88005; Mature: 88005

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRTQAILLLGAALTLGSATQASAAGLSRSLYEKALRGDKQTVGVIVRFSFPNTARGRAL
CCCCCEEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCHHHH
FKTARQQLSARIAQLGPAAGFIQQALNSGRATQLWLDQSVYLPMTPAQAQAVSLLPYVDA
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHH
VFENFKVQVPKAVALSAASAPAGTPWHLQKIGAPQAWAAGFRGQNVRIGHLDTGIDPNHP
HHHCCEEECCHHHEEECCCCCCCCCHHHHHCCCCHHHHHCCCCCCEEEEECCCCCCCCCH
ELAGKLAAFAEFNAEGDRVQSQPHDTTNHGTHTAGLLVGKDVGVAPQAKLISALVLPNNE
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHEEEEEECCCC
GTFAQVIAGMQYVLDPDNNADTDDGADVVNMSLGIPGTYNEFIVPVQNMLKAGVVPVFAI
CHHHHHHHCCEEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEE
GNFGPGSATTGSPGNLPDAIGVGAVDQNGQVASFSSRGPVAWQGQINGVFVKPDIAAPGV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCEEEECCCCCCCCC
NITSTFPNGQYGALSGTSQASPIAAGAVALLLSAKPGSSVDAIKNALFSSASNAGSKNNN
EEEECCCCCCCCCCCCCCCCCCHHHCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCC
VGYGLISVPGALAKLGVNVGGSQPTPQPQPQPTPQPQPQPQPQPQPQPQPQPQPQPQPQP
CEEEEEECCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TPQPQPTGPAGYTLCAVEGGTCTNVANKQVAFGTAGRYVYGTNDASPSFKCTVEEWGGND
CCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCEEEECCCCCCCEEEEEHCCCCCC
PARGQLKGCFVKNSSGSPAPAPTPAPAPQPPSSGKKPSVLLVDDDMGQGADVTNALRDAI
CCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHH
KANAASGGAFVWNTQTQGAVPLDQLQRADIVIWATGEQYQNTITPQDQNTLRQYLAGGGR
HCCCCCCCEEEEECCCCCCCCHHHHCCCCEEEEECCHHHHCCCCCCCHHHHHHHHCCCCE
LLVTGQDVGYDIGNSDFYRSVLKTRFVADSSGTPKFVTRGAFGNTAFTLNAQGSAGNQYY
EEEECCCCCCCCCCHHHHHHHHHHHHEECCCCCCCEEEECCCCCEEEEEECCCCCCCCCC
PDVIADLNGSQVVASWGSANANAGTITAQSIRVDPNKNRAQQKVEDPRGLVERLAANVIG
CHHHHCCCCCEEEEECCCCCCCCCEEEEEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHH
SILNQVLGGQQPTQRPRVTAQNAGENAGAIVVNDAGKYRTVNMGFGLEGLSPNSRNLLIK
HHHHHHHCCCCCCCCCCCEECCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCEEEEE
TSFDWLMR
ECHHHHCC
>Mature Secondary Structure
MKRTQAILLLGAALTLGSATQASAAGLSRSLYEKALRGDKQTVGVIVRFSFPNTARGRAL
CCCCCEEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCHHHH
FKTARQQLSARIAQLGPAAGFIQQALNSGRATQLWLDQSVYLPMTPAQAQAVSLLPYVDA
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEECCCEEECCCCCHHHHHHHHHHHHH
VFENFKVQVPKAVALSAASAPAGTPWHLQKIGAPQAWAAGFRGQNVRIGHLDTGIDPNHP
HHHCCEEECCHHHEEECCCCCCCCCHHHHHCCCCHHHHHCCCCCCEEEEECCCCCCCCCH
ELAGKLAAFAEFNAEGDRVQSQPHDTTNHGTHTAGLLVGKDVGVAPQAKLISALVLPNNE
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHEEEEEECCCC
GTFAQVIAGMQYVLDPDNNADTDDGADVVNMSLGIPGTYNEFIVPVQNMLKAGVVPVFAI
CHHHHHHHCCEEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEE
GNFGPGSATTGSPGNLPDAIGVGAVDQNGQVASFSSRGPVAWQGQINGVFVKPDIAAPGV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCEEEECCCCCCCCC
NITSTFPNGQYGALSGTSQASPIAAGAVALLLSAKPGSSVDAIKNALFSSASNAGSKNNN
EEEECCCCCCCCCCCCCCCCCCHHHCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCC
VGYGLISVPGALAKLGVNVGGSQPTPQPQPQPTPQPQPQPQPQPQPQPQPQPQPQPQPQP
CEEEEEECCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TPQPQPTGPAGYTLCAVEGGTCTNVANKQVAFGTAGRYVYGTNDASPSFKCTVEEWGGND
CCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCEEEECCCCCCCEEEEEHCCCCCC
PARGQLKGCFVKNSSGSPAPAPTPAPAPQPPSSGKKPSVLLVDDDMGQGADVTNALRDAI
CCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHH
KANAASGGAFVWNTQTQGAVPLDQLQRADIVIWATGEQYQNTITPQDQNTLRQYLAGGGR
HCCCCCCCEEEEECCCCCCCCHHHHCCCCEEEEECCHHHHCCCCCCCHHHHHHHHCCCCE
LLVTGQDVGYDIGNSDFYRSVLKTRFVADSSGTPKFVTRGAFGNTAFTLNAQGSAGNQYY
EEEECCCCCCCCCCHHHHHHHHHHHHEECCCCCCCEEEECCCCCEEEEEECCCCCCCCCC
PDVIADLNGSQVVASWGSANANAGTITAQSIRVDPNKNRAQQKVEDPRGLVERLAANVIG
CHHHHCCCCCEEEEECCCCCCCCCEEEEEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHH
SILNQVLGGQQPTQRPRVTAQNAGENAGAIVVNDAGKYRTVNMGFGLEGLSPNSRNLLIK
HHHHHHHCCCCCCCCCCCEECCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCEEEEE
TSFDWLMR
ECHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2106512; 2118514; 2108961; 9384377; 3139638; 2106671 [H]