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The map label for this gene is leuD [H]

Identifier: 94985256

GI number: 94985256

Start: 1226204

End: 1226713

Strand: Reverse

Name: leuD [H]

Synonym: Dgeo_1154

Alternate gene names: 94985256

Gene position: 1226713-1226204 (Counterclockwise)

Preceding gene: 94985257

Following gene: 94985255

Centisome position: 49.72

GC content: 64.31

Gene sequence:

>510_bases
ATGCCCCGAGTCTGGAAATTCGGCGACTCCGTCAATACCGACGACATCCTCCCCGGCAAGTTTGCGCCCTTCATGGCGGG
CGAGGACGTGTTTCAGACCTTCGCCTTTCACTACCTCCGCCCGGAGTTCGCCGCCCAGGTCCAGCCCGGCGATGTGCTGG
TCGGCGGGCGTAACTGGGGCCTGGGTTCCAGCCGCGAGTACGCGCCGCAGGCCCTCAAGAAGCTCCGTATTGGCGGCATC
ATCGCCCCCTCGTTTGCCCGCATTCATTACCGCAACCTGCTGAACCTGGGGATTCCCGCCTTCGAGGCGGATCTGACAGG
CGTTCTCCAGGACGGTGATGAGGTCAGCTTGGACGTGGAAACGGGGGTGTTGACCTACGCGGGCGGGACCATTCAGCTGC
CGCCGCCGCCTGAGTTCCTGCGCGAGGCGCTGCGCGAAGGGAGCATCCTGGCCTTTTTCAAGAAGTATGGCCGTTTTCCA
GGCGAACCGCCCGCAGAGAGCGGCCCGTAA

Upstream 100 bases:

>100_bases
GAACACCCTCTTGTTGGGGTCGCAGTTCCTGTTTTTTGCCCGTCACCGTCCCGTCATTGAATGGGAGCGGCCCTGAAGCC
GCTCCGGAAGGAGACCTCCT

Downstream 100 bases:

>100_bases
ACTGGGCGTATGGCGACCCTGGAGATTGTCTGCCCCGTATGCGCGGAGGTGCTGGAACTCACCGACGCCGACCGTTCCGA
GTTGCAGGTGGGCGACGTGA

Product: 3-isopropylmalate dehydratase small subunit

Products: NA

Alternate protein names: Alpha-IPM isomerase 1; IPMI 1; Isopropylmalate isomerase 1 [H]

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MPRVWKFGDSVNTDDILPGKFAPFMAGEDVFQTFAFHYLRPEFAAQVQPGDVLVGGRNWGLGSSREYAPQALKKLRIGGI
IAPSFARIHYRNLLNLGIPAFEADLTGVLQDGDEVSLDVETGVLTYAGGTIQLPPPPEFLREALREGSILAFFKKYGRFP
GEPPAESGP

Sequences:

>Translated_169_residues
MPRVWKFGDSVNTDDILPGKFAPFMAGEDVFQTFAFHYLRPEFAAQVQPGDVLVGGRNWGLGSSREYAPQALKKLRIGGI
IAPSFARIHYRNLLNLGIPAFEADLTGVLQDGDEVSLDVETGVLTYAGGTIQLPPPPEFLREALREGSILAFFKKYGRFP
GEPPAESGP
>Mature_168_residues
PRVWKFGDSVNTDDILPGKFAPFMAGEDVFQTFAFHYLRPEFAAQVQPGDVLVGGRNWGLGSSREYAPQALKKLRIGGII
APSFARIHYRNLLNLGIPAFEADLTGVLQDGDEVSLDVETGVLTYAGGTIQLPPPPEFLREALREGSILAFFKKYGRFPG
EPPAESGP

Specific function: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate [H]

COG id: COG0066

COG function: function code E; 3-isopropylmalate dehydratase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the leuD family. LeuD type 2 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012305
- InterPro:   IPR015937
- InterPro:   IPR015928
- InterPro:   IPR000573
- InterPro:   IPR011827 [H]

Pfam domain/function: PF00694 Aconitase_C [H]

EC number: =4.2.1.33 [H]

Molecular weight: Translated: 18466; Mature: 18335

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRVWKFGDSVNTDDILPGKFAPFMAGEDVFQTFAFHYLRPEFAAQVQPGDVLVGGRNWG
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCHHHHCCCCCCCEEECCCCCC
LGSSREYAPQALKKLRIGGIIAPSFARIHYRNLLNLGIPAFEADLTGVLQDGDEVSLDVE
CCCCCCHHHHHHHHHHCCCEECCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEEC
TGVLTYAGGTIQLPPPPEFLREALREGSILAFFKKYGRFPGEPPAESGP
CCEEEECCCEEECCCCHHHHHHHHHCCCEEEHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
PRVWKFGDSVNTDDILPGKFAPFMAGEDVFQTFAFHYLRPEFAAQVQPGDVLVGGRNWG
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCHHHHCCCCCCCEEECCCCCC
LGSSREYAPQALKKLRIGGIIAPSFARIHYRNLLNLGIPAFEADLTGVLQDGDEVSLDVE
CCCCCCHHHHHHHHHHCCCEECCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEEC
TGVLTYAGGTIQLPPPPEFLREALREGSILAFFKKYGRFPGEPPAESGP
CCEEEECCCEEECCCCHHHHHHHHHCCCEEEHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]