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The map label for this gene is yqhT [H]

Identifier: 94985191

GI number: 94985191

Start: 1156317

End: 1157363

Strand: Reverse

Name: yqhT [H]

Synonym: Dgeo_1087

Alternate gene names: 94985191

Gene position: 1157363-1156317 (Counterclockwise)

Preceding gene: 94985202

Following gene: 94985190

Centisome position: 46.91

GC content: 70.77

Gene sequence:

>1047_bases
ATGGCTTCATTACGCGAGTTGAGGACCGCCCTCAAGGCGGCAGGCGTGGACGCCCTCTGGGTGAGCGACCCAGCGAACGT
GCGTGCTCTGAGCGGCTTTTCGAGCGGCAAGGATGGCAAGGTGCTGGTCACCGGCGACAGCGCGACACTCTACACCGACG
CGCGCTACACCGTGCAGGCACAGGAGGAGTCGCGCCTGCCCCAGGTGATTGCTCGCCCGCCTGAGACGTATCAGGACGCG
GCGGCTCGGGTGCAGGGCCAGCGGGTGGGCTTCGAAGCCGAACACCTCACGGTCGCCGGATGGGAAGCGCTGCGCGAGCA
CTGGGACGCGACGCTGGTGCCGACGCGCGGCCTGGTGGAAGGCGTGCGGCGGGTAAAAGCGCCCGAGGAGGTGCAGGCGA
TCCGCGCGGCGCAGGCCATCGCAGACCGCGTGTTTGAGGCGGTGCGCCCGACCATCCAGGCGGGGGTGCGCGAGCTGGAC
GTGGCGCTGGCGCTCGAGCTGGGACTGCGGCGTGCGGGGGCGGAAGTGGGCTTTGACGTGATTGTGGCGAGCGGGCCGCG
CGGGGCGATGCCGCACGGTGTGGCCTCGGCGCGGGTGATCGAGGACGGTGACCTGGTGACGATCGATTTTGGTGCGCGGG
TCGGGGGCTACCACTCCGATATGACACGGACGGTGGCGGTGGGCCAGCCGTCCGCGGAACTGCGCCGCATCTACCGCGCC
GTGTTGGAGGCTGAGACGGCGGCGGTGGCGGCCATTCGGCCGGGCGCGCAAGCGGGTGAGCTGGATGCCCTGGCCCGCGG
CATTCTGGAACGGCACGGTTTGGGTGAGGCGTTCGCGCACTCGCTGGGGCATGGCGTCGGCCTCAGCATCCACGAGGGTC
CCAGCTTGCGGGCAGGCAGTGAGGACGTGCTGGAGCCGGGCATGGTGGTCACGGTGGAGCCGGGGGCGTACCTGCCGGGG
CTGGGTGGCGTGCGGATCGAGGATCTGGTGCTGGTGACCGAGAGCGGCCACGAGGTGCTGAGCCGCGCGCCCAAGGAGCA
GCTGTGA

Upstream 100 bases:

>100_bases
GTATAAGCCGCATTGCACGTTCTTCGGCGCCTTGTCCCCCCAGTGGGGACAGGAAGCAAAGGCCCGGTGTGGGGTGCGGG
GCCGTGTTACCTTCCGCCTC

Downstream 100 bases:

>100_bases
GGGTGCGGCTGGCGCTTGCGGCGCTGCTGCTGGCCAGCTCGGCCGGGGCGGCGGGCACCTACCGGGTCAAGCCGGGAGAT
TCGCTCTGGACCGTAGCCCG

Product: peptidase M24

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MASLRELRTALKAAGVDALWVSDPANVRALSGFSSGKDGKVLVTGDSATLYTDARYTVQAQEESRLPQVIARPPETYQDA
AARVQGQRVGFEAEHLTVAGWEALREHWDATLVPTRGLVEGVRRVKAPEEVQAIRAAQAIADRVFEAVRPTIQAGVRELD
VALALELGLRRAGAEVGFDVIVASGPRGAMPHGVASARVIEDGDLVTIDFGARVGGYHSDMTRTVAVGQPSAELRRIYRA
VLEAETAAVAAIRPGAQAGELDALARGILERHGLGEAFAHSLGHGVGLSIHEGPSLRAGSEDVLEPGMVVTVEPGAYLPG
LGGVRIEDLVLVTESGHEVLSRAPKEQL

Sequences:

>Translated_348_residues
MASLRELRTALKAAGVDALWVSDPANVRALSGFSSGKDGKVLVTGDSATLYTDARYTVQAQEESRLPQVIARPPETYQDA
AARVQGQRVGFEAEHLTVAGWEALREHWDATLVPTRGLVEGVRRVKAPEEVQAIRAAQAIADRVFEAVRPTIQAGVRELD
VALALELGLRRAGAEVGFDVIVASGPRGAMPHGVASARVIEDGDLVTIDFGARVGGYHSDMTRTVAVGQPSAELRRIYRA
VLEAETAAVAAIRPGAQAGELDALARGILERHGLGEAFAHSLGHGVGLSIHEGPSLRAGSEDVLEPGMVVTVEPGAYLPG
LGGVRIEDLVLVTESGHEVLSRAPKEQL
>Mature_347_residues
ASLRELRTALKAAGVDALWVSDPANVRALSGFSSGKDGKVLVTGDSATLYTDARYTVQAQEESRLPQVIARPPETYQDAA
ARVQGQRVGFEAEHLTVAGWEALREHWDATLVPTRGLVEGVRRVKAPEEVQAIRAAQAIADRVFEAVRPTIQAGVRELDV
ALALELGLRRAGAEVGFDVIVASGPRGAMPHGVASARVIEDGDLVTIDFGARVGGYHSDMTRTVAVGQPSAELRRIYRAV
LEAETAAVAAIRPGAQAGELDALARGILERHGLGEAFAHSLGHGVGLSIHEGPSLRAGSEDVLEPGMVVTVEPGAYLPGL
GGVRIEDLVLVTESGHEVLSRAPKEQL

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=349, Percent_Identity=28.9398280802292, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI264681563, Length=225, Percent_Identity=35.1111111111111, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI264681565, Length=222, Percent_Identity=34.2342342342342, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI149589008, Length=288, Percent_Identity=27.0833333333333, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI260593665, Length=289, Percent_Identity=26.9896193771626, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI260593663, Length=230, Percent_Identity=29.5652173913043, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI93141226, Length=165, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI164420681, Length=256, Percent_Identity=24.21875, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI40385867, Length=248, Percent_Identity=24.1935483870968, Blast_Score=75, Evalue=8e-14,
Organism=Escherichia coli, GI1788728, Length=359, Percent_Identity=41.7827298050139, Blast_Score=241, Evalue=6e-65,
Organism=Escherichia coli, GI1789275, Length=275, Percent_Identity=32, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1786364, Length=202, Percent_Identity=29.2079207920792, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790282, Length=303, Percent_Identity=22.4422442244224, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17508215, Length=289, Percent_Identity=26.9896193771626, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17509539, Length=307, Percent_Identity=28.0130293159609, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17507601, Length=196, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6321118, Length=283, Percent_Identity=29.3286219081272, Blast_Score=106, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6320922, Length=340, Percent_Identity=23.5294117647059, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322999, Length=174, Percent_Identity=31.6091954022989, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19920384, Length=268, Percent_Identity=29.4776119402985, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21357079, Length=291, Percent_Identity=27.4914089347079, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17137632, Length=165, Percent_Identity=32.7272727272727, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21355531, Length=242, Percent_Identity=23.1404958677686, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24583427, Length=186, Percent_Identity=26.3440860215054, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 36750; Mature: 36619

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLRELRTALKAAGVDALWVSDPANVRALSGFSSGKDGKVLVTGDSATLYTDARYTVQA
CCHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCCCCEEEEECCCEEEEECCEEEEEC
QEESRLPQVIARPPETYQDAAARVQGQRVGFEAEHLTVAGWEALREHWDATLVPTRGLVE
CHHHCCHHHHCCCCHHHHHHHHHHCCHHCCCCCCEEEEHHHHHHHHHCCCEECCCHHHHH
GVRRVKAPEEVQAIRAAQAIADRVFEAVRPTIQAGVRELDVALALELGLRRAGAEVGFDV
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
IVASGPRGAMPHGVASARVIEDGDLVTIDFGARVGGYHSDMTRTVAVGQPSAELRRIYRA
EEECCCCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCCEEEECCCCHHHHHHHHHH
VLEAETAAVAAIRPGAQAGELDALARGILERHGLGEAFAHSLGHGVGLSIHEGPSLRAGS
HHHHHHHHEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEECCCCCCCCC
EDVLEPGMVVTVEPGAYLPGLGGVRIEDLVLVTESGHEVLSRAPKEQL
HHHCCCCEEEEECCCCCCCCCCCCEEEEEEEEECCCHHHHHCCCCCCC
>Mature Secondary Structure 
ASLRELRTALKAAGVDALWVSDPANVRALSGFSSGKDGKVLVTGDSATLYTDARYTVQA
CHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCCCCEEEEECCCEEEEECCEEEEEC
QEESRLPQVIARPPETYQDAAARVQGQRVGFEAEHLTVAGWEALREHWDATLVPTRGLVE
CHHHCCHHHHCCCCHHHHHHHHHHCCHHCCCCCCEEEEHHHHHHHHHCCCEECCCHHHHH
GVRRVKAPEEVQAIRAAQAIADRVFEAVRPTIQAGVRELDVALALELGLRRAGAEVGFDV
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
IVASGPRGAMPHGVASARVIEDGDLVTIDFGARVGGYHSDMTRTVAVGQPSAELRRIYRA
EEECCCCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCCEEEECCCCHHHHHHHHHH
VLEAETAAVAAIRPGAQAGELDALARGILERHGLGEAFAHSLGHGVGLSIHEGPSLRAGS
HHHHHHHHEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEECCCCCCCCC
EDVLEPGMVVTVEPGAYLPGLGGVRIEDLVLVTESGHEVLSRAPKEQL
HHHCCCCEEEEECCCCCCCCCCCCEEEEEEEEECCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]