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The map label for this gene is sipU [H]

Identifier: 94985180

GI number: 94985180

Start: 1145710

End: 1146489

Strand: Reverse

Name: sipU [H]

Synonym: Dgeo_1076

Alternate gene names: 94985180

Gene position: 1146489-1145710 (Counterclockwise)

Preceding gene: 94985181

Following gene: 94985174

Centisome position: 46.47

GC content: 64.74

Gene sequence:

>780_bases
ATGACAAGACTGAACAAACCCGCGCCGGGACCGCTCGGGAAACTGTGGAAGGAAGTGCTGGAACCCATCGTCTTCGCGGT
GGTGATCACGCAGTTCGTGGCGACGCTGGTCGGAGTGGACGGCGTGAGCATGATGCCGAACCTGCGTGACCATGAGCGCG
TGTTCGTGCCGAAATACGAGACGTGGCTGCACAAGGCGGGCGTCGGCGACTTCCACCGTGGGGACATCCTGATCTTCAAG
CCCCCCCGTGAGGCAGCCGCACAAGCCCCCAACCTCACCAAGAGTGCCTTTGGTCTGTGGACCTATCGCCCCTTTCTGAT
CAAACGCTTGATTGGCCTGCCCGGCGACCGGGTGCGGGTGGAGGGCGGCCAGGTGTATGTCAACGGTGTGCGGCTAGATC
AGAGCTGGACGACCGACTACTGGCGCGAGCAGGGCTGCTGGGACACCCAGAGCGACCTGGCCAATCACGCCACCTCCAGC
GCCGCGGGTATCCTGCCCGACCAGCCCGAAATCACGGTGCCCCCCGGCCATTACTTTGTGATGGGAGACAACCGCACGGC
GGGCGGCAGCGAGGACTCGCGCCTGTTCGGGCCGGTGGCCAAGCGTGATATCGCCGGGCGCGCAGTCGCGGTGATCTGGC
CGATCATGCGCAAGGCCAACGCCCGCTACGACTGCTCAACCGGGCGGGTCGCAGAGTTCAGCGGGCCAAATGTGCTGAAC
TGGCGCCTGCTGAAGCGGCCCGAAGCCTTCGATACCCTCAAGACGCAGCTGGCGAAGTAG

Upstream 100 bases:

>100_bases
GCTGCCGCAGCTGAGGGCGCTGCTTTCCTGACCCGCCGGCGGGGGAAGCACGCGGGGAAGGGCTGCCGTCCGCTATCCTG
CGCGGCGGACAAGGAGCCGC

Downstream 100 bases:

>100_bases
CTCTCGCGCGGTCGGCAGCGGAGCGTTGGCCCCGGCAAGGGTCAGCGCTCTTTCCTGTTGGAGCAGCTCGCCCGCCGTCA
GTCCTCGTCGCCGCCCAGCA

Product: peptidase S26A, signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MTRLNKPAPGPLGKLWKEVLEPIVFAVVITQFVATLVGVDGVSMMPNLRDHERVFVPKYETWLHKAGVGDFHRGDILIFK
PPREAAAQAPNLTKSAFGLWTYRPFLIKRLIGLPGDRVRVEGGQVYVNGVRLDQSWTTDYWREQGCWDTQSDLANHATSS
AAGILPDQPEITVPPGHYFVMGDNRTAGGSEDSRLFGPVAKRDIAGRAVAVIWPIMRKANARYDCSTGRVAEFSGPNVLN
WRLLKRPEAFDTLKTQLAK

Sequences:

>Translated_259_residues
MTRLNKPAPGPLGKLWKEVLEPIVFAVVITQFVATLVGVDGVSMMPNLRDHERVFVPKYETWLHKAGVGDFHRGDILIFK
PPREAAAQAPNLTKSAFGLWTYRPFLIKRLIGLPGDRVRVEGGQVYVNGVRLDQSWTTDYWREQGCWDTQSDLANHATSS
AAGILPDQPEITVPPGHYFVMGDNRTAGGSEDSRLFGPVAKRDIAGRAVAVIWPIMRKANARYDCSTGRVAEFSGPNVLN
WRLLKRPEAFDTLKTQLAK
>Mature_258_residues
TRLNKPAPGPLGKLWKEVLEPIVFAVVITQFVATLVGVDGVSMMPNLRDHERVFVPKYETWLHKAGVGDFHRGDILIFKP
PREAAAQAPNLTKSAFGLWTYRPFLIKRLIGLPGDRVRVEGGQVYVNGVRLDQSWTTDYWREQGCWDTQSDLANHATSSA
AGILPDQPEITVPPGHYFVMGDNRTAGGSEDSRLFGPVAKRDIAGRAVAVIWPIMRKANARYDCSTGRVAEFSGPNVLNW
RLLKRPEAFDTLKTQLAK

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 28836; Mature: 28705

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS00760 SPASE_I_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRLNKPAPGPLGKLWKEVLEPIVFAVVITQFVATLVGVDGVSMMPNLRDHERVFVPKYE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCEEECCCHH
TWLHKAGVGDFHRGDILIFKPPREAAAQAPNLTKSAFGLWTYRPFLIKRLIGLPGDRVRV
HHHHHCCCCCCCCCCEEEECCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEE
EGGQVYVNGVRLDQSWTTDYWREQGCWDTQSDLANHATSSAAGILPDQPEITVPPGHYFV
ECCEEEEEEEEECCCCCHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCEEECCCEEEE
MGDNRTAGGSEDSRLFGPVAKRDIAGRAVAVIWPIMRKANARYDCSTGRVAEFSGPNVLN
EECCCCCCCCCCCHHCCHHHHHHHCCCHHHHHHHHHHHCCCCEECCCCCEEECCCCCEEE
WRLLKRPEAFDTLKTQLAK
EEEECCCCHHHHHHHHHCC
>Mature Secondary Structure 
TRLNKPAPGPLGKLWKEVLEPIVFAVVITQFVATLVGVDGVSMMPNLRDHERVFVPKYE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCEEECCCHH
TWLHKAGVGDFHRGDILIFKPPREAAAQAPNLTKSAFGLWTYRPFLIKRLIGLPGDRVRV
HHHHHCCCCCCCCCCEEEECCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEE
EGGQVYVNGVRLDQSWTTDYWREQGCWDTQSDLANHATSSAAGILPDQPEITVPPGHYFV
ECCEEEEEEEEECCCCCHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCEEECCCEEEE
MGDNRTAGGSEDSRLFGPVAKRDIAGRAVAVIWPIMRKANARYDCSTGRVAEFSGPNVLN
EECCCCCCCCCCCHHCCHHHHHHHCCCHHHHHHHHHHHCCCCEECCCCCEEECCCCCEEE
WRLLKRPEAFDTLKTQLAK
EEEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9823656 [H]