Click here to switch to the map view.

The map label for this gene is yngJ [H]

Identifier: 94984843

GI number: 94984843

Start: 797229

End: 798368

Strand: Reverse

Name: yngJ [H]

Synonym: Dgeo_0736

Alternate gene names: 94984843

Gene position: 798368-797229 (Counterclockwise)

Preceding gene: 94984846

Following gene: 94984842

Centisome position: 32.36

GC content: 61.4

Gene sequence:

>1140_bases
ATGATCGATTTTACCCTCACCGACGAGCAAAAACAGCTCCAGCAACTCGCGCGTGACTTTACCCGCAAGGAGATTATTCC
GGTGGCCGCCGAGTACGACCAGAAGGAAGAACTGCCCTGGCAAGTGGTCGAAAAGGCTTTCGAGGTCGGCCTGCTGAATA
TCGCCATTCCCGAACACGCGGGCGGCCTGGGTCTGGGGATGCTCGACGAATGCATCATCGGAGAAGAGCTGGCCTACGGC
TGCATGGGCATCTATACGGTTCTGATGGCCTCGGAACTGGGCATCACGCCAATTTTGGTGGGCGGCACCGAAGAGCAGCA
GAAGCGCTTCCTGACCCCGCTCACCGAAAAGCCCGCCTTGGCAGCCTTTGCCCTCAGCGAGCCGAACAACGGTTCCGACG
CCGCCGCTATGAGCACGACTGCCGTGCTGGACGGCGACGAGTGGGTGATCAACGGAACGAAAATGTGGATCAGCAACGGC
GGCGTGGCGGACATCACCGTGGTCTTTGCCACCACCAATCGCCAAGGCGGGCACCGGGCGACGGTGGCGCTGGTGGTGCC
CAAGGACGCTCCCGGGTTCAGCTTCAACAAGATCAAGCACAAGATGGGACAGCGCGCCAGCCTGACCAGTGAACTCGTCT
TCGAGAATGTCCGCGTTCCCAAGGAAAACCAGCTCGGCGGGGTGGGAGACGGATTCAAGATCGCCATGAAGACGCTCGAC
AAGACCCGTATCCCGGTCGCCGCCGGATCGGTCGGGGTCGCCCGCCGCGCGCTGGAGGAGAGCTTGAAGTATGCCAAGCA
GCGTGAGGCGTTCGGCCAGCCGATCGCACAGTTCCAAGCGATCCAATTCAAACTGGCCGAGATGGCCATGGGCATTGAGA
CCGGGCGCCTGATGACCTGGAAGGCTGCCTGGCTGGTGGACCAGGGGCTGCCCCACGGCTACGAGAGTGCCATCGCCAAG
GCCTACTGCTCGGAGATGGCCTTTGACGCCGCCAACGAGGCGATCCAGATTCACGGCGGTTACGGCTATGTGGGCGAGTA
TCCGGTCGAAAAGCTGCTGCGCGACGTGAAACTCAACCAGATCTACGAGGGCACCAACGAGATTCAGCGCGTGGTGATCA
GCCGCCACCTGCTGAGATAA

Upstream 100 bases:

>100_bases
GGTGCATGTTAAATTGAACCGAGTCCAGCTGTAGACGGTTCAGAGAAGCCCTGCTCCTCTGTCCGACGAGGTTCTTTCCC
TTCTTCACAGGAGTCCTGTC

Downstream 100 bases:

>100_bases
AAACCGCCGCACCGCCCCGGGGACGTGACGCTGCCGCCACGTCCCCGCCTTGTATCTGCAAGCAACCTGCTGAGCTTGAC
TTCCCCCGTCTCCAACCCGA

Product: acyl-CoA dehydrogenase-like protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MIDFTLTDEQKQLQQLARDFTRKEIIPVAAEYDQKEELPWQVVEKAFEVGLLNIAIPEHAGGLGLGMLDECIIGEELAYG
CMGIYTVLMASELGITPILVGGTEEQQKRFLTPLTEKPALAAFALSEPNNGSDAAAMSTTAVLDGDEWVINGTKMWISNG
GVADITVVFATTNRQGGHRATVALVVPKDAPGFSFNKIKHKMGQRASLTSELVFENVRVPKENQLGGVGDGFKIAMKTLD
KTRIPVAAGSVGVARRALEESLKYAKQREAFGQPIAQFQAIQFKLAEMAMGIETGRLMTWKAAWLVDQGLPHGYESAIAK
AYCSEMAFDAANEAIQIHGGYGYVGEYPVEKLLRDVKLNQIYEGTNEIQRVVISRHLLR

Sequences:

>Translated_379_residues
MIDFTLTDEQKQLQQLARDFTRKEIIPVAAEYDQKEELPWQVVEKAFEVGLLNIAIPEHAGGLGLGMLDECIIGEELAYG
CMGIYTVLMASELGITPILVGGTEEQQKRFLTPLTEKPALAAFALSEPNNGSDAAAMSTTAVLDGDEWVINGTKMWISNG
GVADITVVFATTNRQGGHRATVALVVPKDAPGFSFNKIKHKMGQRASLTSELVFENVRVPKENQLGGVGDGFKIAMKTLD
KTRIPVAAGSVGVARRALEESLKYAKQREAFGQPIAQFQAIQFKLAEMAMGIETGRLMTWKAAWLVDQGLPHGYESAIAK
AYCSEMAFDAANEAIQIHGGYGYVGEYPVEKLLRDVKLNQIYEGTNEIQRVVISRHLLR
>Mature_379_residues
MIDFTLTDEQKQLQQLARDFTRKEIIPVAAEYDQKEELPWQVVEKAFEVGLLNIAIPEHAGGLGLGMLDECIIGEELAYG
CMGIYTVLMASELGITPILVGGTEEQQKRFLTPLTEKPALAAFALSEPNNGSDAAAMSTTAVLDGDEWVINGTKMWISNG
GVADITVVFATTNRQGGHRATVALVVPKDAPGFSFNKIKHKMGQRASLTSELVFENVRVPKENQLGGVGDGFKIAMKTLD
KTRIPVAAGSVGVARRALEESLKYAKQREAFGQPIAQFQAIQFKLAEMAMGIETGRLMTWKAAWLVDQGLPHGYESAIAK
AYCSEMAFDAANEAIQIHGGYGYVGEYPVEKLLRDVKLNQIYEGTNEIQRVVISRHLLR

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI187960098, Length=378, Percent_Identity=48.1481481481481, Blast_Score=375, Evalue=1e-104,
Organism=Homo sapiens, GI4557231, Length=378, Percent_Identity=48.1481481481481, Blast_Score=375, Evalue=1e-104,
Organism=Homo sapiens, GI4557233, Length=375, Percent_Identity=45.8666666666667, Blast_Score=333, Evalue=1e-91,
Organism=Homo sapiens, GI7656849, Length=375, Percent_Identity=37.6, Blast_Score=260, Evalue=1e-69,
Organism=Homo sapiens, GI4501859, Length=375, Percent_Identity=35.7333333333333, Blast_Score=248, Evalue=9e-66,
Organism=Homo sapiens, GI21361497, Length=352, Percent_Identity=38.6363636363636, Blast_Score=235, Evalue=5e-62,
Organism=Homo sapiens, GI226958412, Length=376, Percent_Identity=35.3723404255319, Blast_Score=231, Evalue=9e-61,
Organism=Homo sapiens, GI4501857, Length=375, Percent_Identity=34.1333333333333, Blast_Score=226, Evalue=3e-59,
Organism=Homo sapiens, GI226958414, Length=332, Percent_Identity=36.4457831325301, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI4557235, Length=383, Percent_Identity=36.8146214099217, Blast_Score=211, Evalue=7e-55,
Organism=Homo sapiens, GI76496475, Length=383, Percent_Identity=36.8146214099217, Blast_Score=211, Evalue=7e-55,
Organism=Homo sapiens, GI4503943, Length=373, Percent_Identity=28.9544235924933, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI7669494, Length=361, Percent_Identity=28.808864265928, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI211971008, Length=404, Percent_Identity=29.2079207920792, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI48976061, Length=404, Percent_Identity=29.2079207920792, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI38505218, Length=402, Percent_Identity=28.6069651741293, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI218563752, Length=236, Percent_Identity=27.1186440677966, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1786223, Length=380, Percent_Identity=28.9473684210526, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI87081958, Length=385, Percent_Identity=32.4675324675325, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI87082384, Length=294, Percent_Identity=26.1904761904762, Blast_Score=82, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17570075, Length=380, Percent_Identity=46.5789473684211, Blast_Score=357, Evalue=6e-99,
Organism=Caenorhabditis elegans, GI17534899, Length=381, Percent_Identity=45.6692913385827, Blast_Score=345, Evalue=2e-95,
Organism=Caenorhabditis elegans, GI17569725, Length=380, Percent_Identity=45.2631578947368, Blast_Score=344, Evalue=3e-95,
Organism=Caenorhabditis elegans, GI17508101, Length=371, Percent_Identity=37.466307277628, Blast_Score=256, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI17533517, Length=364, Percent_Identity=36.8131868131868, Blast_Score=243, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI17506239, Length=371, Percent_Identity=35.0404312668464, Blast_Score=242, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI17538396, Length=379, Percent_Identity=37.2031662269129, Blast_Score=236, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI71985184, Length=381, Percent_Identity=32.2834645669291, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI71990804, Length=306, Percent_Identity=35.6209150326797, Blast_Score=198, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17505929, Length=370, Percent_Identity=31.3513513513514, Blast_Score=167, Evalue=9e-42,
Organism=Caenorhabditis elegans, GI17534353, Length=373, Percent_Identity=27.6139410187668, Blast_Score=161, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI71985192, Length=327, Percent_Identity=31.1926605504587, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17551932, Length=367, Percent_Identity=28.3378746594005, Blast_Score=158, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=37.2294372294372, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI71982178, Length=274, Percent_Identity=30.6569343065693, Blast_Score=151, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI17531909, Length=241, Percent_Identity=29.4605809128631, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17562446, Length=349, Percent_Identity=28.3667621776504, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17531913, Length=176, Percent_Identity=28.4090909090909, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI86563383, Length=275, Percent_Identity=26.9090909090909, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI86563381, Length=275, Percent_Identity=26.9090909090909, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24660351, Length=377, Percent_Identity=53.5809018567639, Blast_Score=409, Evalue=1e-114,
Organism=Drosophila melanogaster, GI21356377, Length=375, Percent_Identity=44.2666666666667, Blast_Score=330, Evalue=1e-90,
Organism=Drosophila melanogaster, GI24646207, Length=374, Percent_Identity=44.9197860962567, Blast_Score=323, Evalue=1e-88,
Organism=Drosophila melanogaster, GI24666513, Length=375, Percent_Identity=37.0666666666667, Blast_Score=254, Evalue=7e-68,
Organism=Drosophila melanogaster, GI21355753, Length=381, Percent_Identity=35.9580052493438, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI281363737, Length=384, Percent_Identity=36.4583333333333, Blast_Score=213, Evalue=1e-55,
Organism=Drosophila melanogaster, GI19920834, Length=380, Percent_Identity=28.1578947368421, Blast_Score=140, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 41464; Mature: 41464

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDFTLTDEQKQLQQLARDFTRKEIIPVAAEYDQKEELPWQVVEKAFEVGLLNIAIPEHA
CCEEEECCHHHHHHHHHHHHHHHHCEEHHHCCCCCCCCCHHHHHHHHHCCEEEEECCCCC
GGLGLGMLDECIIGEELAYGCMGIYTVLMASELGITPILVGGTEEQQKRFLTPLTEKPAL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHCCCCCCCCCE
AAFALSEPNNGSDAAAMSTTAVLDGDEWVINGTKMWISNGGVADITVVFATTNRQGGHRA
EEEEECCCCCCCCHHHHEEEEEECCCEEEEECEEEEEECCCEEEEEEEEEECCCCCCCEE
TVALVVPKDAPGFSFNKIKHKMGQRASLTSELVFENVRVPKENQLGGVGDGFKIAMKTLD
EEEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
KTRIPVAAGSVGVARRALEESLKYAKQREAFGQPIAQFQAIQFKLAEMAMGIETGRLMTW
HCCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEE
KAAWLVDQGLPHGYESAIAKAYCSEMAFDAANEAIQIHGGYGYVGEYPVEKLLRDVKLNQ
EHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHH
IYEGTNEIQRVVISRHLLR
HHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIDFTLTDEQKQLQQLARDFTRKEIIPVAAEYDQKEELPWQVVEKAFEVGLLNIAIPEHA
CCEEEECCHHHHHHHHHHHHHHHHCEEHHHCCCCCCCCCHHHHHHHHHCCEEEEECCCCC
GGLGLGMLDECIIGEELAYGCMGIYTVLMASELGITPILVGGTEEQQKRFLTPLTEKPAL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHCCCCCCCCCE
AAFALSEPNNGSDAAAMSTTAVLDGDEWVINGTKMWISNGGVADITVVFATTNRQGGHRA
EEEEECCCCCCCCHHHHEEEEEECCCEEEEECEEEEEECCCEEEEEEEEEECCCCCCCEE
TVALVVPKDAPGFSFNKIKHKMGQRASLTSELVFENVRVPKENQLGGVGDGFKIAMKTLD
EEEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
KTRIPVAAGSVGVARRALEESLKYAKQREAFGQPIAQFQAIQFKLAEMAMGIETGRLMTW
HCCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEE
KAAWLVDQGLPHGYESAIAKAYCSEMAFDAANEAIQIHGGYGYVGEYPVEKLLRDVKLNQ
EHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHH
IYEGTNEIQRVVISRHLLR
HHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]