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The map label for this gene is ygbD [C]

Identifier: 94984818

GI number: 94984818

Start: 769870

End: 771222

Strand: Reverse

Name: ygbD [C]

Synonym: Dgeo_0711

Alternate gene names: 94984818

Gene position: 771222-769870 (Counterclockwise)

Preceding gene: 94984821

Following gene: 94984816

Centisome position: 31.26

GC content: 70.44

Gene sequence:

>1353_bases
ATGCGAATCGTGGTGGTGGGTGGGGTGGCGGCGGGCATGAGCGCGGCGAGTCGAGCGAGGCGGCAGAACCCGCAAGCGCA
GGTTACGGTCTTCGAGCGCGGCGGGGAGATCAGCTACGGCGCCTGTGGCCTCCCCTACGTGATCGGCGGTGAGGTACCCG
GCTTCGAGCGCCTGATCGCCCGCACGCCCGAGCAGATGCGCGCGCAGGGAATCGACGTGCGCCTGCGCCACGAGGTGACG
GACGTGAATACCGCTACTCGCACTGTCACGGTGCACGACCGGGGAGCGGGCCGTTCCTTCACCGAGCCTTACGACCGCCT
GCTGCTCGCCACGGGGGTAAACGCCATATGGCCGGAGTGGGCCAGCAGCCACCTGCATGCTGTTCACGTCCTGCGCGACC
TTGCCGATGGGCGGGCCATCTTGGCAAGCCTTGCGGGGGCAAGCCGCGCCTGCATCGTCGGTGGCGGCTACATCGGGCTG
GAAATGGCAGAGGCGCTGCGCTCGCGCGGGCTGGAGGTGATCCTGCTGGAAAAGGGACCGGAGGTCGCGGGCCGAATGCT
GGACCGGGCCTCTCAGCAGCGGGTGAGGGCCGAACTGGAGCGGCACGGTGTGGACGTACGCTGCGGAACGACCGTAGAAG
GGCTGGCGGGAAAGGACAGGCGCGTGAGCAGCGTGCAGACAGACGGTGGCCCGGTCCCCGCCGACGTGGTGATCGTGGCT
GTGGGCGTGCAGCCGAACACGGCCCTCGCACGAGCGGCGGGGGCGCGGCTCGGGGAGACGGGCGCTGTCGCCGTGGATGC
CCGGCAGGAAACCAGCGTGGCGGGCGTGTACGCGGCGGGCGACAACACCGAGAGCACCCACCGCGTCACCGGGCAAAAGG
TCCACCTGCCCCTGGGCCTCACCGCCAACCGCATGGGCCGGGTGGCGGGCGTGAACATGGCGGGCGGGGATGCCCGCTTT
CCCGGCATCGTCGGCACCGGCATCTTCAAGGCGTTCGACCTGGGAGCAGCCCGCACCGGCGTCACGCAGGCGGAGGCAGA
AGGGCTGGGGCTGAAGGCCGTCAGCGTGGACGTGGACAGCACCGACCACGCCGAGTACTACCCCGACGCCGCGCCTATCC
ACGTGCGGCTGACCGGCGAGCGTGGCAGCGGACGGCTGCTGGGCGTGCAACTCGTGGGCCAGCCCGAGAGCGTCAAGCGG
GTGGACGTGGTCGCCGCGCTCCTCCACCAAGGCGGCAGCGCGCAGGACCTCTTCGAGCTGGACCTCGCCTACGCTCCGCC
TTTTTCCAGTGTGTGGGACGTGCTGCTGGTGGCAGCGGACCGACTGGGGCGGGAACTCTGCGAGGAAGGCTAG

Upstream 100 bases:

>100_bases
GGCCAGGGCCAGCAGGGACAGCGCCAGCCGGGCAGCGCGGCACGGCGCGGCGGAGGAGAGGGGCTTCACCCCTCCAGGCT
AGCGGGTCTACCCTCAGGTC

Downstream 100 bases:

>100_bases
GGCCGAGCCGGTCCAGCAGGCGCAGGCCGCCCCTCCGGTCCCAGGCCAAGGCATGCCGTCCGCCAGACAGCAGGGCGAGG
AGGTGCTCACTGTGGCAGGC

Product: FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Products: NA

Alternate protein names: CoA-disulfide reductase; CoADR [H]

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MRIVVVGGVAAGMSAASRARRQNPQAQVTVFERGGEISYGACGLPYVIGGEVPGFERLIARTPEQMRAQGIDVRLRHEVT
DVNTATRTVTVHDRGAGRSFTEPYDRLLLATGVNAIWPEWASSHLHAVHVLRDLADGRAILASLAGASRACIVGGGYIGL
EMAEALRSRGLEVILLEKGPEVAGRMLDRASQQRVRAELERHGVDVRCGTTVEGLAGKDRRVSSVQTDGGPVPADVVIVA
VGVQPNTALARAAGARLGETGAVAVDARQETSVAGVYAAGDNTESTHRVTGQKVHLPLGLTANRMGRVAGVNMAGGDARF
PGIVGTGIFKAFDLGAARTGVTQAEAEGLGLKAVSVDVDSTDHAEYYPDAAPIHVRLTGERGSGRLLGVQLVGQPESVKR
VDVVAALLHQGGSAQDLFELDLAYAPPFSSVWDVLLVAADRLGRELCEEG

Sequences:

>Translated_450_residues
MRIVVVGGVAAGMSAASRARRQNPQAQVTVFERGGEISYGACGLPYVIGGEVPGFERLIARTPEQMRAQGIDVRLRHEVT
DVNTATRTVTVHDRGAGRSFTEPYDRLLLATGVNAIWPEWASSHLHAVHVLRDLADGRAILASLAGASRACIVGGGYIGL
EMAEALRSRGLEVILLEKGPEVAGRMLDRASQQRVRAELERHGVDVRCGTTVEGLAGKDRRVSSVQTDGGPVPADVVIVA
VGVQPNTALARAAGARLGETGAVAVDARQETSVAGVYAAGDNTESTHRVTGQKVHLPLGLTANRMGRVAGVNMAGGDARF
PGIVGTGIFKAFDLGAARTGVTQAEAEGLGLKAVSVDVDSTDHAEYYPDAAPIHVRLTGERGSGRLLGVQLVGQPESVKR
VDVVAALLHQGGSAQDLFELDLAYAPPFSSVWDVLLVAADRLGRELCEEG
>Mature_450_residues
MRIVVVGGVAAGMSAASRARRQNPQAQVTVFERGGEISYGACGLPYVIGGEVPGFERLIARTPEQMRAQGIDVRLRHEVT
DVNTATRTVTVHDRGAGRSFTEPYDRLLLATGVNAIWPEWASSHLHAVHVLRDLADGRAILASLAGASRACIVGGGYIGL
EMAEALRSRGLEVILLEKGPEVAGRMLDRASQQRVRAELERHGVDVRCGTTVEGLAGKDRRVSSVQTDGGPVPADVVIVA
VGVQPNTALARAAGARLGETGAVAVDARQETSVAGVYAAGDNTESTHRVTGQKVHLPLGLTANRMGRVAGVNMAGGDARF
PGIVGTGIFKAFDLGAARTGVTQAEAEGLGLKAVSVDVDSTDHAEYYPDAAPIHVRLTGERGSGRLLGVQLVGQPESVKR
VDVVAALLHQGGSAQDLFELDLAYAPPFSSVWDVLLVAADRLGRELCEEG

Specific function: Unknown

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI65787454, Length=333, Percent_Identity=27.027027027027, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI226437568, Length=333, Percent_Identity=27.027027027027, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI21389617, Length=333, Percent_Identity=27.027027027027, Blast_Score=93, Evalue=6e-19,
Organism=Escherichia coli, GI1789065, Length=329, Percent_Identity=26.4437689969605, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789765, Length=312, Percent_Identity=27.2435897435897, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17559934, Length=247, Percent_Identity=26.7206477732794, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24585130, Length=334, Percent_Identity=26.9461077844311, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24639257, Length=344, Percent_Identity=26.7441860465116, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI281359715, Length=344, Percent_Identity=26.7441860465116, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI281359713, Length=344, Percent_Identity=26.7441860465116, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24639250, Length=344, Percent_Identity=26.7441860465116, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI18543267, Length=344, Percent_Identity=26.7441860465116, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24639252, Length=344, Percent_Identity=26.7441860465116, Blast_Score=96, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017758
- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.14 [H]

Molecular weight: Translated: 47185; Mature: 47185

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVVVGGVAAGMSAASRARRQNPQAQVTVFERGGEISYGACGLPYVIGGEVPGFERLIA
CEEEEEECHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCEEECCCCCCHHHHHH
RTPEQMRAQGIDVRLRHEVTDVNTATRTVTVHDRGAGRSFTEPYDRLLLATGVNAIWPEW
CCCHHHHHCCCCEEEEEEEECCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCHH
ASSHLHAVHVLRDLADGRAILASLAGASRACIVGGGYIGLEMAEALRSRGLEVILLEKGP
HHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCEEEEEECCC
EVAGRMLDRASQQRVRAELERHGVDVRCGTTVEGLAGKDRRVSSVQTDGGPVPADVVIVA
HHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHCCCCCCCCCCEECCCCCCCCCEEEEEE
VGVQPNTALARAAGARLGETGAVAVDARQETSVAGVYAAGDNTESTHRVTGQKVHLPLGL
ECCCCCHHHHHHHCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCEEECCCEEEEEECC
TANRMGRVAGVNMAGGDARFPGIVGTGIFKAFDLGAARTGVTQAEAEGLGLKAVSVDVDS
CHHHCCCEEECEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHCCCCEEEEEEECCC
TDHAEYYPDAAPIHVRLTGERGSGRLLGVQLVGQPESVKRVDVVAALLHQGGSAQDLFEL
CCCCCCCCCCCCEEEEEECCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCEEE
DLAYAPPFSSVWDVLLVAADRLGRELCEEG
HEECCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRIVVVGGVAAGMSAASRARRQNPQAQVTVFERGGEISYGACGLPYVIGGEVPGFERLIA
CEEEEEECHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCEEECCCCCCHHHHHH
RTPEQMRAQGIDVRLRHEVTDVNTATRTVTVHDRGAGRSFTEPYDRLLLATGVNAIWPEW
CCCHHHHHCCCCEEEEEEEECCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCHH
ASSHLHAVHVLRDLADGRAILASLAGASRACIVGGGYIGLEMAEALRSRGLEVILLEKGP
HHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCEEEEEECCC
EVAGRMLDRASQQRVRAELERHGVDVRCGTTVEGLAGKDRRVSSVQTDGGPVPADVVIVA
HHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHCCCCCCCCCCEECCCCCCCCCEEEEEE
VGVQPNTALARAAGARLGETGAVAVDARQETSVAGVYAAGDNTESTHRVTGQKVHLPLGL
ECCCCCHHHHHHHCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCCEEECCCEEEEEECC
TANRMGRVAGVNMAGGDARFPGIVGTGIFKAFDLGAARTGVTQAEAEGLGLKAVSVDVDS
CHHHCCCEEECEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHCCCCEEEEEEECCC
TDHAEYYPDAAPIHVRLTGERGSGRLLGVQLVGQPESVKRVDVVAALLHQGGSAQDLFEL
CCCCCCCCCCCCEEEEEECCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCEEE
DLAYAPPFSSVWDVLLVAADRLGRELCEEG
HEECCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA