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The map label for this gene is yqjD [H]

Identifier: 94984596

GI number: 94984596

Start: 506586

End: 508148

Strand: Reverse

Name: yqjD [H]

Synonym: Dgeo_0489

Alternate gene names: 94984596

Gene position: 508148-506586 (Counterclockwise)

Preceding gene: 94984597

Following gene: 94984587

Centisome position: 20.6

GC content: 63.92

Gene sequence:

>1563_bases
ATGACGCAACCGGGCGCAGAACTTCAGGAACTGATCGCCGAGATGGAGCAGCGCCGTGCGAAGATCGAGGCGGGCGGCGG
CCAGGAGCGGCAGCAAAAGCAGCGCGCGGGCGGCAAGCTCACCGCCCGCGAGCGCATCGAACGCCTCCTTGACCCCGGCT
CCTTTCTGGAACTTTCCACCTTCGTCGAGCACGGCCACAACCGCCTGATGGCCGATGTGGAGGCCCCCGGCGAGGGCGTG
GTGACCGGGCGCGGCACTATTGGCGGGCGGCAGGTCTTTGTGTTCAGCCAGGATTTCACGGTGCTGGGCGGTTCACTGGG
CAAGATGAACGCCGCCAAGGTCACCAAGGTGATGGACCTGGCCGCCAAGACCGGCTGCCCGGTGATTGGCCTGAACGACT
CGGCGGGCGCGCGCATTCAGGAGGGCGTAGATTCCCTGAGTGGCTACGGCGAGATCTTCTACCGCAACGCAATCTACTCC
GGCAGTATCCCGCAGATCAGCGCGATCCTGGGGCCGTGTGCGGGCGGCGCGGTCTACTCGCCGGCCCTGACCGACTTCAT
CCTGATGAGCCGCGGCACGTCGTACATGTTCATCACCGGGCCGGAAGTCATCAAGAGCGTCACCCGCGAGGACGTGACCT
TTGATCAGCTGGGCGGTGCGGACGTGCATACGCGCAAAAGCGGCGTGGCCCATCTGGAATATGACGGTGACGAGGCGGTT
CTAGACGGGATCCGCGAACTGCTCTCCTACCTGCCGCAGAATGCCCGCGAGCAGCCGCCCGTGCGCACATGCACCGACCC
GCTGGACCGCCCGAATACTCGCCTCCTGGAGATCATCACACCCGACCAGCGCAAGCCCTACGCGATGCATGACGTGATCC
ACGAGCTGGTGGACGACGGTCAATTTTTGGAAATCCAGCCGGGATGGGCGAAGAACATCCTCTGCGGCTTCGCGCGGCTA
AACGGCTTTCCGGTGGGCATCGTGGCCAACAACCCTAAGGTGATGGCGGGCACGCTGAATATTGACGCCTCAGACAAGGC
CGCCCGCTTCATCCGTACCTGCGACTGCTACAACATCCCGATCCTGACGCTGGTGGACGTGACGGGCTTCCTGCCGGGTG
TAGCGCAGGAGCACGCCGGGATTATCCGCCACGGCGCCAAGATGCTCTACGCCTATGCCGAGGCGACCGTCCCCAAGATC
ACGCTCATTACGCGCAAGAGCTACGGCGGCGCCTACCTCGCCATGAACAGCCGCGACATGGGCGCCGACGTGGTATATGC
CTGGCCGACCGCAGCCGTCGCCGTGATGGGCGCGGAGGGGGCTGCCAACATCGTCTACCGCCGCGAGATTCAGAACTCCG
AGAATCCCGCCGCCACCCGCGCCGAGAAGATCAAGCAGTACAAGGATACCTTCGATAACCCCTATGTGGCCGCCGCCAAG
GGCTATATCGACGACGTGATCCCCATCGAGGACACCCGCCGAATTCTGATCCAGACTTTCGCCATGCTGCGGGGCAAGGA
AGAGGCGCGGCCTTTCAAAAAGCACGGGAATATGCCGCTGTAA

Upstream 100 bases:

>100_bases
CTGCCCTCAAGCGGTGCGAAGACCTCCACCGCTGCCCTGCCTTGTCCCCCTGCTAGGAACGCATGAGCGGCTTAGATGCC
TGCCCGGGTAGCATGGCGGC

Downstream 100 bases:

>100_bases
GGGCAGGCGCCCTTCTTGCCAGCAAGCGTGGGGCGCTCTGCTGGCACCGCCTTTGCCGCCGCCGCGGCCAGACACCGCAC
GTTCAGCAGCCTGCCTGGCT

Product: carboxyl transferase

Products: NA

Alternate protein names: PCCase; Propanoyl-CoA:carbon dioxide ligase [H]

Number of amino acids: Translated: 520; Mature: 519

Protein sequence:

>520_residues
MTQPGAELQELIAEMEQRRAKIEAGGGQERQQKQRAGGKLTARERIERLLDPGSFLELSTFVEHGHNRLMADVEAPGEGV
VTGRGTIGGRQVFVFSQDFTVLGGSLGKMNAAKVTKVMDLAAKTGCPVIGLNDSAGARIQEGVDSLSGYGEIFYRNAIYS
GSIPQISAILGPCAGGAVYSPALTDFILMSRGTSYMFITGPEVIKSVTREDVTFDQLGGADVHTRKSGVAHLEYDGDEAV
LDGIRELLSYLPQNAREQPPVRTCTDPLDRPNTRLLEIITPDQRKPYAMHDVIHELVDDGQFLEIQPGWAKNILCGFARL
NGFPVGIVANNPKVMAGTLNIDASDKAARFIRTCDCYNIPILTLVDVTGFLPGVAQEHAGIIRHGAKMLYAYAEATVPKI
TLITRKSYGGAYLAMNSRDMGADVVYAWPTAAVAVMGAEGAANIVYRREIQNSENPAATRAEKIKQYKDTFDNPYVAAAK
GYIDDVIPIEDTRRILIQTFAMLRGKEEARPFKKHGNMPL

Sequences:

>Translated_520_residues
MTQPGAELQELIAEMEQRRAKIEAGGGQERQQKQRAGGKLTARERIERLLDPGSFLELSTFVEHGHNRLMADVEAPGEGV
VTGRGTIGGRQVFVFSQDFTVLGGSLGKMNAAKVTKVMDLAAKTGCPVIGLNDSAGARIQEGVDSLSGYGEIFYRNAIYS
GSIPQISAILGPCAGGAVYSPALTDFILMSRGTSYMFITGPEVIKSVTREDVTFDQLGGADVHTRKSGVAHLEYDGDEAV
LDGIRELLSYLPQNAREQPPVRTCTDPLDRPNTRLLEIITPDQRKPYAMHDVIHELVDDGQFLEIQPGWAKNILCGFARL
NGFPVGIVANNPKVMAGTLNIDASDKAARFIRTCDCYNIPILTLVDVTGFLPGVAQEHAGIIRHGAKMLYAYAEATVPKI
TLITRKSYGGAYLAMNSRDMGADVVYAWPTAAVAVMGAEGAANIVYRREIQNSENPAATRAEKIKQYKDTFDNPYVAAAK
GYIDDVIPIEDTRRILIQTFAMLRGKEEARPFKKHGNMPL
>Mature_519_residues
TQPGAELQELIAEMEQRRAKIEAGGGQERQQKQRAGGKLTARERIERLLDPGSFLELSTFVEHGHNRLMADVEAPGEGVV
TGRGTIGGRQVFVFSQDFTVLGGSLGKMNAAKVTKVMDLAAKTGCPVIGLNDSAGARIQEGVDSLSGYGEIFYRNAIYSG
SIPQISAILGPCAGGAVYSPALTDFILMSRGTSYMFITGPEVIKSVTREDVTFDQLGGADVHTRKSGVAHLEYDGDEAVL
DGIRELLSYLPQNAREQPPVRTCTDPLDRPNTRLLEIITPDQRKPYAMHDVIHELVDDGQFLEIQPGWAKNILCGFARLN
GFPVGIVANNPKVMAGTLNIDASDKAARFIRTCDCYNIPILTLVDVTGFLPGVAQEHAGIIRHGAKMLYAYAEATVPKIT
LITRKSYGGAYLAMNSRDMGADVVYAWPTAAVAVMGAEGAANIVYRREIQNSENPAATRAEKIKQYKDTFDNPYVAAAKG
YIDDVIPIEDTRRILIQTFAMLRGKEEARPFKKHGNMPL

Specific function: This Protein Is A Component Of The Acetyl Coenzyme A Carboxylase Complex; First, Biotin Carboxylase Catalyzes The Carboxylation Of The Carrier Protein And Then The Transcarboxylase Transfers The Carboxyl Group To Form Malonyl-CoA. [C]

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=509, Percent_Identity=55.4027504911591, Blast_Score=560, Evalue=1e-159,
Organism=Homo sapiens, GI295821216, Length=529, Percent_Identity=53.3081285444234, Blast_Score=548, Evalue=1e-156,
Organism=Homo sapiens, GI11545863, Length=510, Percent_Identity=34.7058823529412, Blast_Score=267, Evalue=2e-71,
Organism=Homo sapiens, GI134142062, Length=347, Percent_Identity=23.6311239193084, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI38679974, Length=472, Percent_Identity=23.3050847457627, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI38679960, Length=472, Percent_Identity=23.3050847457627, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI38679977, Length=472, Percent_Identity=23.3050847457627, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI38679967, Length=472, Percent_Identity=23.3050847457627, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI38679971, Length=472, Percent_Identity=23.3050847457627, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1788655, Length=188, Percent_Identity=28.7234042553192, Blast_Score=76, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI25147362, Length=508, Percent_Identity=54.5275590551181, Blast_Score=566, Evalue=1e-161,
Organism=Caenorhabditis elegans, GI25147359, Length=508, Percent_Identity=54.5275590551181, Blast_Score=565, Evalue=1e-161,
Organism=Caenorhabditis elegans, GI17552936, Length=508, Percent_Identity=32.6771653543307, Blast_Score=268, Evalue=6e-72,
Organism=Caenorhabditis elegans, GI71997163, Length=310, Percent_Identity=25.4838709677419, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI133931226, Length=307, Percent_Identity=23.4527687296417, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6323863, Length=409, Percent_Identity=23.4718826405868, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6324343, Length=345, Percent_Identity=24.3478260869565, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24586065, Length=519, Percent_Identity=34.1040462427746, Blast_Score=258, Evalue=6e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.3 [H]

Molecular weight: Translated: 56581; Mature: 56450

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQPGAELQELIAEMEQRRAKIEAGGGQERQQKQRAGGKLTARERIERLLDPGSFLELST
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHH
FVEHGHNRLMADVEAPGEGVVTGRGTIGGRQVFVFSQDFTVLGGSLGKMNAAKVTKVMDL
HHHCCCCEEEEEECCCCCCEEEECCCCCCEEEEEEECCCCEECCCCCCCCHHHHHHHHHH
AAKTGCPVIGLNDSAGARIQEGVDSLSGYGEIFYRNAIYSGSIPQISAILGPCAGGAVYS
HHHCCCCEEECCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHCCCCCCCCCC
PALTDFILMSRGTSYMFITGPEVIKSVTREDVTFDQLGGADVHTRKSGVAHLEYDGDEAV
HHHHHHHHHCCCCCEEEEECHHHHHHHHHCCCCHHHCCCCCCEECCCCCEEEEECCCHHH
LDGIRELLSYLPQNAREQPPVRTCTDPLDRPNTRLLEIITPDQRKPYAMHDVIHELVDDG
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCC
QFLEIQPGWAKNILCGFARLNGFPVGIVANNPKVMAGTLNIDASDKAARFIRTCDCYNIP
CEEEECCCHHHHHHHHHHHHCCEEEEEEECCCEEEEEEEECCCCHHHHHHHHHCCCCCCC
ILTLVDVTGFLPGVAQEHAGIIRHGAKMLYAYAEATVPKITLITRKSYGGAYLAMNSRDM
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEECCCCC
GADVVYAWPTAAVAVMGAEGAANIVYRREIQNSENPAATRAEKIKQYKDTFDNPYVAAAK
CCCEEEECCCEEEEEECCCCCHHHEEEEHHCCCCCCHHHHHHHHHHHHHHCCCCEEEECC
GYIDDVIPIEDTRRILIQTFAMLRGKEEARPFKKHGNMPL
CCCCCCCCCHHHHHHHHHHHHHHHCCHHCCHHHHCCCCCC
>Mature Secondary Structure 
TQPGAELQELIAEMEQRRAKIEAGGGQERQQKQRAGGKLTARERIERLLDPGSFLELST
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHH
FVEHGHNRLMADVEAPGEGVVTGRGTIGGRQVFVFSQDFTVLGGSLGKMNAAKVTKVMDL
HHHCCCCEEEEEECCCCCCEEEECCCCCCEEEEEEECCCCEECCCCCCCCHHHHHHHHHH
AAKTGCPVIGLNDSAGARIQEGVDSLSGYGEIFYRNAIYSGSIPQISAILGPCAGGAVYS
HHHCCCCEEECCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHCCCCCCCCCC
PALTDFILMSRGTSYMFITGPEVIKSVTREDVTFDQLGGADVHTRKSGVAHLEYDGDEAV
HHHHHHHHHCCCCCEEEEECHHHHHHHHHCCCCHHHCCCCCCEECCCCCEEEEECCCHHH
LDGIRELLSYLPQNAREQPPVRTCTDPLDRPNTRLLEIITPDQRKPYAMHDVIHELVDDG
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCC
QFLEIQPGWAKNILCGFARLNGFPVGIVANNPKVMAGTLNIDASDKAARFIRTCDCYNIP
CEEEECCCHHHHHHHHHHHHCCEEEEEEECCCEEEEEEEECCCCHHHHHHHHHCCCCCCC
ILTLVDVTGFLPGVAQEHAGIIRHGAKMLYAYAEATVPKITLITRKSYGGAYLAMNSRDM
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEECCCCC
GADVVYAWPTAAVAVMGAEGAANIVYRREIQNSENPAATRAEKIKQYKDTFDNPYVAAAK
CCCEEEECCCEEEEEECCCCCHHHEEEEHHCCCCCCHHHHHHHHHHHHHHCCCCEEEECC
GYIDDVIPIEDTRRILIQTFAMLRGKEEARPFKKHGNMPL
CCCCCCCCCHHHHHHHHHHHHHHHCCHHCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]