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The map label for this gene is ade

Identifier: 94984528

GI number: 94984528

Start: 427961

End: 429655

Strand: Reverse

Name: ade

Synonym: Dgeo_0420

Alternate gene names: 94984528

Gene position: 429655-427961 (Counterclockwise)

Preceding gene: 94984529

Following gene: 94984527

Centisome position: 17.41

GC content: 73.22

Gene sequence:

>1695_bases
ATGACCACAGCAAGCGCGGCGAGTGAGCGGGCGGTGCGGCAACGGCTGGTGCGGGTTGCCCGGGGTCTGGAAGCAGGTGA
CCTGCTGGTTCGCGGCGCCCAGGTGGTCCAGCCCGCCACCGGCGAGGTGTTCGGGGCGGATGTGCTGGTTGCGGAGGGCC
GGGTGGCGGCGCTTGTGGGTCCAGGGTTGGGTGTACGGGCCGCGCGGACGGTGGAGGCACGCGGTGCCTACCTCGCCCCC
GGCTTCCTGGACGCGCACATCCACATCGAGTCCAGCCTGCTCACCCCCGCGCGCTTTGCGGCAGCGGTGTTGCCGCGCGG
CACGACGGCGGTGGTAGCCGAACCGCACGAGACCGTAAACGTGATGGGCCTGAGCGGACTCCGGTGGATGCTGGAAGCCG
GGAAAGGATCGGGCCTGCGGGTCTTCGGCTCGGTGCCGTCCTCGGTGCCCGCCAGCCCCTTCGAGTGTGGCGGCGCGGTG
CTGGACGCGGCGGAGGTGGCCGAGGCGCTGCGCCTACCGGGCGTGCTGGGCCTCGCGGAGATGATGAACTATCCGGGCGT
GCTGAACCTGGAACGCGGGGCGTGGGAGGTGCTGGACGCCGGATACGGGGGGCGCATCGACGGGCACGCGGCGGGCGTGG
CGGGCCGCGACCTGCAAGCCTACGCGGCGGCCGGTCCCCACTCCGACCACGAGGCGACCACGCCGGAGGAGGCCCGCGAA
CGCCTGCGCGCCGGGCTGTGGCTGATGGTGCGCGAGGGGTCGGCGGCCAGAAACCTGGAAGCCCTGCTCCCCGTGCTGCG
CGAACGCCCCCGCCGCGCGATGCTGGTGAGTGACGACGTGAGCGTGGACGAGCTGCTCTCGCTCGGGCACCTCGACCGCC
TGCTGCGGGCCTGCGTGGCGGGCGGCCTGCACCCCGCCGACGCGGTCGCGCTGGTGACCTGCAACCCCGCAGAGTACTGG
GGCCTGCACGACCTGGGCCTGGTCGCGCCGGGCTACCACGCGGATTTTGTGCTGCTGCGCGACCTGGAGCGGTTCGAGGT
GCTGGACACCTTCGTGGGCGGTGTGGAGGCGCAGGCCGGCAGCGAGACGCCTCCCCTCCCGGGCGGCGGCGTGAACCTGG
GGCCGAGCTGGGCAACCGCCACCTTCGAGGTTCCCGCGAGCTGGCCGGTGATGCAGGTTCGCCCCGACCAGATCACGACC
GGGGTGGGCGCACCGGGGTCGGGCGACGCCCGGCTGGTGGTCGCGGACCGCTACGGGCGCGGCGAACACGCGGCCTGCTG
GACTTCTGGCACGGGTCTGACCGGGGGAGCGCTGGCGATCAGCCTGCTGCACGACGCACACCATGTCGCCGTGCTGGGCG
GGAGCAACGCGGACGTGCGGGCGGCGGGCCGGGCGCTGGAAGCCATGGGCGGCGGCGTGGTCGTGGTTGCGGGCGGCGAG
GTGCGCTCAAACCTCCCCCTCCCCTACGCGGGCCTGATGAGCGACCTGCCCCCGCAGGAAGCCGCCGCCCGGCTCTCGGA
GGTAACGGCGGCCGCGCGGGTGCTGGGCTGCACCCTTCCCTACCCGGTCACCACCCTGAGTTTCCTAGGCCTGAGTGTGA
TCCCGGCGCTCAAACTCACGCCACGCGGGCTGCTGGATGTGGGGGCCTGGCAGCTTCTACCACGCGAAACGGTGCGTGTG
GGCGCGGAAGGTTGA

Upstream 100 bases:

>100_bases
GCAAAACCGCGCCTCCGCTGAACGACGCGCAGGCGTTCGCACGCGCGCTGGCCGAGCGGGGGCCAGGGCTGGAGCTGTTC
CGGCGGCGCTAGACTGCGCC

Downstream 100 bases:

>100_bases
CCATGCCAGAGCTGACCGAACATCAGGTCGTCGTGAACGGCGTGCGCCTGCATTGCGTTGCTGCGGGACCGGAAGACGGG
CCGCCCGTGCTGCTGCTACA

Product: adenine deaminase

Products: NA

Alternate protein names: Adenase; Adenine aminase

Number of amino acids: Translated: 564; Mature: 563

Protein sequence:

>564_residues
MTTASAASERAVRQRLVRVARGLEAGDLLVRGAQVVQPATGEVFGADVLVAEGRVAALVGPGLGVRAARTVEARGAYLAP
GFLDAHIHIESSLLTPARFAAAVLPRGTTAVVAEPHETVNVMGLSGLRWMLEAGKGSGLRVFGSVPSSVPASPFECGGAV
LDAAEVAEALRLPGVLGLAEMMNYPGVLNLERGAWEVLDAGYGGRIDGHAAGVAGRDLQAYAAAGPHSDHEATTPEEARE
RLRAGLWLMVREGSAARNLEALLPVLRERPRRAMLVSDDVSVDELLSLGHLDRLLRACVAGGLHPADAVALVTCNPAEYW
GLHDLGLVAPGYHADFVLLRDLERFEVLDTFVGGVEAQAGSETPPLPGGGVNLGPSWATATFEVPASWPVMQVRPDQITT
GVGAPGSGDARLVVADRYGRGEHAACWTSGTGLTGGALAISLLHDAHHVAVLGGSNADVRAAGRALEAMGGGVVVVAGGE
VRSNLPLPYAGLMSDLPPQEAAARLSEVTAAARVLGCTLPYPVTTLSFLGLSVIPALKLTPRGLLDVGAWQLLPRETVRV
GAEG

Sequences:

>Translated_564_residues
MTTASAASERAVRQRLVRVARGLEAGDLLVRGAQVVQPATGEVFGADVLVAEGRVAALVGPGLGVRAARTVEARGAYLAP
GFLDAHIHIESSLLTPARFAAAVLPRGTTAVVAEPHETVNVMGLSGLRWMLEAGKGSGLRVFGSVPSSVPASPFECGGAV
LDAAEVAEALRLPGVLGLAEMMNYPGVLNLERGAWEVLDAGYGGRIDGHAAGVAGRDLQAYAAAGPHSDHEATTPEEARE
RLRAGLWLMVREGSAARNLEALLPVLRERPRRAMLVSDDVSVDELLSLGHLDRLLRACVAGGLHPADAVALVTCNPAEYW
GLHDLGLVAPGYHADFVLLRDLERFEVLDTFVGGVEAQAGSETPPLPGGGVNLGPSWATATFEVPASWPVMQVRPDQITT
GVGAPGSGDARLVVADRYGRGEHAACWTSGTGLTGGALAISLLHDAHHVAVLGGSNADVRAAGRALEAMGGGVVVVAGGE
VRSNLPLPYAGLMSDLPPQEAAARLSEVTAAARVLGCTLPYPVTTLSFLGLSVIPALKLTPRGLLDVGAWQLLPRETVRV
GAEG
>Mature_563_residues
TTASAASERAVRQRLVRVARGLEAGDLLVRGAQVVQPATGEVFGADVLVAEGRVAALVGPGLGVRAARTVEARGAYLAPG
FLDAHIHIESSLLTPARFAAAVLPRGTTAVVAEPHETVNVMGLSGLRWMLEAGKGSGLRVFGSVPSSVPASPFECGGAVL
DAAEVAEALRLPGVLGLAEMMNYPGVLNLERGAWEVLDAGYGGRIDGHAAGVAGRDLQAYAAAGPHSDHEATTPEEARER
LRAGLWLMVREGSAARNLEALLPVLRERPRRAMLVSDDVSVDELLSLGHLDRLLRACVAGGLHPADAVALVTCNPAEYWG
LHDLGLVAPGYHADFVLLRDLERFEVLDTFVGGVEAQAGSETPPLPGGGVNLGPSWATATFEVPASWPVMQVRPDQITTG
VGAPGSGDARLVVADRYGRGEHAACWTSGTGLTGGALAISLLHDAHHVAVLGGSNADVRAAGRALEAMGGGVVVVAGGEV
RSNLPLPYAGLMSDLPPQEAAARLSEVTAAARVLGCTLPYPVTTLSFLGLSVIPALKLTPRGLLDVGAWQLLPRETVRVG
AEG

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family

Homologues:

Organism=Escherichia coli, GI1790098, Length=566, Percent_Identity=37.2791519434629, Blast_Score=300, Evalue=1e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADEC_DEIGD (Q1J1B1)

Other databases:

- EMBL:   CP000359
- RefSeq:   YP_603892.1
- ProteinModelPortal:   Q1J1B1
- STRING:   Q1J1B1
- GeneID:   4057156
- GenomeReviews:   CP000359_GR
- KEGG:   dge:Dgeo_0420
- NMPDR:   fig|68909.1.peg.294
- eggNOG:   COG1001
- HOGENOM:   HBG725357
- OMA:   VGLGEMM
- PhylomeDB:   Q1J1B1
- ProtClustDB:   CLSK445813
- BioCyc:   DGEO319795:DGEO_0420-MONOMER
- HAMAP:   MF_01518
- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01178

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.4.2

Molecular weight: Translated: 58273; Mature: 58142

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTASAASERAVRQRLVRVARGLEAGDLLVRGAQVVQPATGEVFGADVLVAEGRVAALVG
CCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHCCCCCCCEECCEEEEECCCEEEEEC
PGLGVRAARTVEARGAYLAPGFLDAHIHIESSLLTPARFAAAVLPRGTTAVVAEPHETVN
CCCCCCCEEEECCCCCEECCCEEEEEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCEEE
VMGLSGLRWMLEAGKGSGLRVFGSVPSSVPASPFECGGAVLDAAEVAEALRLPGVLGLAE
EEECCCHHHHHCCCCCCCEEEEECCCCCCCCCCHHCCCHHCCHHHHHHHHHCCCHHHHHH
MMNYPGVLNLERGAWEVLDAGYGGRIDGHAAGVAGRDLQAYAAAGPHSDHEATTPEEARE
HHCCCCEEEECCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHHH
RLRAGLWLMVREGSAARNLEALLPVLRERPRRAMLVSDDVSVDELLSLGHLDRLLRACVA
HHHCCEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHH
GGLHPADAVALVTCNPAEYWGLHDLGLVAPGYHADFVLLRDLERFEVLDTFVGGVEAQAG
CCCCCCCEEEEEEECCHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCCCCC
SETPPLPGGGVNLGPSWATATFEVPASWPVMQVRPDQITTGVGAPGSGDARLVVADRYGR
CCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEECCCHHCCCCCCCCCCCEEEEEEECCCC
GEHAACWTSGTGLTGGALAISLLHDAHHVAVLGGSNADVRAAGRALEAMGGGVVVVAGGE
CCCCEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEECCC
VRSNLPLPYAGLMSDLPPQEAAARLSEVTAAARVLGCTLPYPVTTLSFLGLSVIPALKLT
CCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
PRGLLDVGAWQLLPRETVRVGAEG
CCCHHHCCHHHHCCHHHHCCCCCC
>Mature Secondary Structure 
TTASAASERAVRQRLVRVARGLEAGDLLVRGAQVVQPATGEVFGADVLVAEGRVAALVG
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHCCCCCCCEECCEEEEECCCEEEEEC
PGLGVRAARTVEARGAYLAPGFLDAHIHIESSLLTPARFAAAVLPRGTTAVVAEPHETVN
CCCCCCCEEEECCCCCEECCCEEEEEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCEEE
VMGLSGLRWMLEAGKGSGLRVFGSVPSSVPASPFECGGAVLDAAEVAEALRLPGVLGLAE
EEECCCHHHHHCCCCCCCEEEEECCCCCCCCCCHHCCCHHCCHHHHHHHHHCCCHHHHHH
MMNYPGVLNLERGAWEVLDAGYGGRIDGHAAGVAGRDLQAYAAAGPHSDHEATTPEEARE
HHCCCCEEEECCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHHH
RLRAGLWLMVREGSAARNLEALLPVLRERPRRAMLVSDDVSVDELLSLGHLDRLLRACVA
HHHCCEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHH
GGLHPADAVALVTCNPAEYWGLHDLGLVAPGYHADFVLLRDLERFEVLDTFVGGVEAQAG
CCCCCCCEEEEEEECCHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCCCCC
SETPPLPGGGVNLGPSWATATFEVPASWPVMQVRPDQITTGVGAPGSGDARLVVADRYGR
CCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEECCCHHCCCCCCCCCCCEEEEEEECCCC
GEHAACWTSGTGLTGGALAISLLHDAHHVAVLGGSNADVRAAGRALEAMGGGVVVVAGGE
CCCCEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEECCC
VRSNLPLPYAGLMSDLPPQEAAARLSEVTAAARVLGCTLPYPVTTLSFLGLSVIPALKLT
CCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
PRGLLDVGAWQLLPRETVRVGAEG
CCCHHHCCHHHHCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA