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The map label for this gene is yuxL [H]

Identifier: 94984473

GI number: 94984473

Start: 370256

End: 372250

Strand: Reverse

Name: yuxL [H]

Synonym: Dgeo_0365

Alternate gene names: 94984473

Gene position: 372250-370256 (Counterclockwise)

Preceding gene: 94984476

Following gene: 94984471

Centisome position: 15.09

GC content: 68.52

Gene sequence:

>1995_bases
ATGGCGCACTCCAACCCGGCCATGCCTGGCCCCGAGAGCCTGCTTGCTCTCGCTTTCCCATCCGACCCCCAGGTCAGCCC
CGATGGACAGCGGGTGGTCTTTGTTCTGTCGCGGATCGAGGAGGAAGACCCCCAGCGGCCCGATCCTGCCTTTGCGCGGC
CCCGCTACAAGTCGCAGCTTTGGCTTTCGGGCGGTGGAGAAGCCCAGCCCCTCACTCGGGGCGAGGGGCGCGACAGCTCG
CCGCGCTGGTCACCCGATGGTCAGACGCTCGCCTTTGTGCGGGAGGAGGGCGGGCAGAAGGGCCAGCTCTTCCTGCTGCC
ACTGACCGGGGGCGAAGCAAAACGAATCACCCGCTTTCGGGGTGCGGTCCAGGACGTGCAGTGGAGTCCGGATGGCCGCT
TTCTGACTTTTCTGAGCACCGCTGACGACGAGGACAGACGCGACGAGCGCGGCGAGGCTCGGGTGATCACCCGCCCGCGC
TACCGCTTCAACGGGCGCGACTGGCTGCCCGAACGCCCCGCTCGCCTCTGGCGCTACGACGTGGCGGCAGAAGAGCTGCA
CGAGTGGCTCACGCCGGACGTGGAAGTCACGGGCTATGCCTGGTGGCCCGACAGCCGGGGGGTCTTGCTCGTTTCCAGCC
GCAGCGAGGAGGACGCAGCGCACTGGCGCCAGGAGGCGAACACCCTGCACCTGGACGGCGAACGCACCCACCTGACCCGC
TGGAACTCAGCCATCGACGCGGTGATTCCCCACCCCGACGGCCAGCGCTTCGCCCTGGTGGGCCGTCCTGAGGGCAAAGG
CAGCCCAGAAGACCACCACCTTTTCCTGGTGGGGCCGGACGGTGCCTGGCAGCGGCTCGACGAGGGGTGGGACCGGCCCA
TCGGCAACCTGGTGGGGGGCGACTGTCACGTGGGTGCTTTCCCCTCGCGGCCCGTGTGGCTGGATGCAGAAACGCTGCTC
GTGTCCAGCACGGTGGGCGGCGCCTGCGGCCTGTTCCGGGTCCGGCTGGACGGCACGGTCACCGCCCAGGACCACGATCC
GCAGGCCGTGATTGCCGCCTTCACCGCCCGCGGGGACGGCGTGGCCCTGATCCGCGAGCGGGCGGACCGTTTTCCGGAAG
TGGAGTTGAACGGCCTACAGGTCACAGCTCTGCACCGCCGCCTCCCCTTCCCTACCCGTACCCCGCGGCGCGTCACCTTC
ACCAATGAGCTGGGCGAGGGCGAGGGCTGGGTGCTGCTACCGGAGGGCGAAGGTCGCGCCCCCGCCCTGCTCAGCATCCA
TGGCGGCCCGCACACCGCCTACGGGCACGCCTTTATGCACGAGTTTCAGCTGTTCGCAGCGCGGGGATACGGGGTGTGCT
ACGGCAACCCGCGTGGCAGTGCCGGCTACGGGCAGGCGTGGACCTCGGCCATCCACGGGCGCTGGGGCACGGTGGACATG
GCCGATCTGCTGGCCTTTTTCGACGCTTGCCTCGCGGCAGAGCACCGACTCGACCCCCGGCGAACGGCGGTGATGGGCGG
CAGTTACGGCGGCTACATGACGAACTGGATCACGGGGCACACAGATCGCTTCCAGGCCGCGATCACCGACCGCTCGATCT
GCAACCTGATCTCCTTCGGGGGGACCAGCGACATCGGCATGCGCTTCTGGGATGACGAACTCGGCCTAAATTTCCACCGC
AGCGAAGGCGCCCTGCGGCTCTGGGACATGAGTCCTCTCAAGTACGTGGAGAACGTGCGCACCCCCACCCTGATCATCCA
CTCGGTGCTTGACCACCGCTGCCCGATTGAGCAGGCCGAGCAGTGGTACACGGCGCTGAAGCTCCACGGCGTCCCGGTGC
GCTTCGTGCGCTTTCCGGGCGAGGACCACGAGCTTTCACGCTCGGGGCGTCCGGACCGGCGCTTGAGGCGGCTGGAGGAG
TATCTGGAGTGGCTGGAAGAATGGGTGCCGGGGGCAGCACAGCAGGAGCAGCGCACAGCAGACACCCGCGCGTAG

Upstream 100 bases:

>100_bases
AGTGTAGGTCGGGCCCCTCTGGGAAGCACGAGAAGGGCCGCCTCACACCTTGAGTAAAGCCTCATGAGCCAGATGCGCTC
AACTTGTGCTTGACTGCAGT

Downstream 100 bases:

>100_bases
GTCAGTCTGCGAGCCAAAGGAGAAGGCCGGGAATTGTTTCCCGGCCCACGCTCTTCTTTCCTTATTCCTCGTCGCGGCGC
TTGTTGCCCCAGCCCCGATC

Product: peptidase S9, prolyl oligopeptidase active site region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 664; Mature: 663

Protein sequence:

>664_residues
MAHSNPAMPGPESLLALAFPSDPQVSPDGQRVVFVLSRIEEEDPQRPDPAFARPRYKSQLWLSGGGEAQPLTRGEGRDSS
PRWSPDGQTLAFVREEGGQKGQLFLLPLTGGEAKRITRFRGAVQDVQWSPDGRFLTFLSTADDEDRRDERGEARVITRPR
YRFNGRDWLPERPARLWRYDVAAEELHEWLTPDVEVTGYAWWPDSRGVLLVSSRSEEDAAHWRQEANTLHLDGERTHLTR
WNSAIDAVIPHPDGQRFALVGRPEGKGSPEDHHLFLVGPDGAWQRLDEGWDRPIGNLVGGDCHVGAFPSRPVWLDAETLL
VSSTVGGACGLFRVRLDGTVTAQDHDPQAVIAAFTARGDGVALIRERADRFPEVELNGLQVTALHRRLPFPTRTPRRVTF
TNELGEGEGWVLLPEGEGRAPALLSIHGGPHTAYGHAFMHEFQLFAARGYGVCYGNPRGSAGYGQAWTSAIHGRWGTVDM
ADLLAFFDACLAAEHRLDPRRTAVMGGSYGGYMTNWITGHTDRFQAAITDRSICNLISFGGTSDIGMRFWDDELGLNFHR
SEGALRLWDMSPLKYVENVRTPTLIIHSVLDHRCPIEQAEQWYTALKLHGVPVRFVRFPGEDHELSRSGRPDRRLRRLEE
YLEWLEEWVPGAAQQEQRTADTRA

Sequences:

>Translated_664_residues
MAHSNPAMPGPESLLALAFPSDPQVSPDGQRVVFVLSRIEEEDPQRPDPAFARPRYKSQLWLSGGGEAQPLTRGEGRDSS
PRWSPDGQTLAFVREEGGQKGQLFLLPLTGGEAKRITRFRGAVQDVQWSPDGRFLTFLSTADDEDRRDERGEARVITRPR
YRFNGRDWLPERPARLWRYDVAAEELHEWLTPDVEVTGYAWWPDSRGVLLVSSRSEEDAAHWRQEANTLHLDGERTHLTR
WNSAIDAVIPHPDGQRFALVGRPEGKGSPEDHHLFLVGPDGAWQRLDEGWDRPIGNLVGGDCHVGAFPSRPVWLDAETLL
VSSTVGGACGLFRVRLDGTVTAQDHDPQAVIAAFTARGDGVALIRERADRFPEVELNGLQVTALHRRLPFPTRTPRRVTF
TNELGEGEGWVLLPEGEGRAPALLSIHGGPHTAYGHAFMHEFQLFAARGYGVCYGNPRGSAGYGQAWTSAIHGRWGTVDM
ADLLAFFDACLAAEHRLDPRRTAVMGGSYGGYMTNWITGHTDRFQAAITDRSICNLISFGGTSDIGMRFWDDELGLNFHR
SEGALRLWDMSPLKYVENVRTPTLIIHSVLDHRCPIEQAEQWYTALKLHGVPVRFVRFPGEDHELSRSGRPDRRLRRLEE
YLEWLEEWVPGAAQQEQRTADTRA
>Mature_663_residues
AHSNPAMPGPESLLALAFPSDPQVSPDGQRVVFVLSRIEEEDPQRPDPAFARPRYKSQLWLSGGGEAQPLTRGEGRDSSP
RWSPDGQTLAFVREEGGQKGQLFLLPLTGGEAKRITRFRGAVQDVQWSPDGRFLTFLSTADDEDRRDERGEARVITRPRY
RFNGRDWLPERPARLWRYDVAAEELHEWLTPDVEVTGYAWWPDSRGVLLVSSRSEEDAAHWRQEANTLHLDGERTHLTRW
NSAIDAVIPHPDGQRFALVGRPEGKGSPEDHHLFLVGPDGAWQRLDEGWDRPIGNLVGGDCHVGAFPSRPVWLDAETLLV
SSTVGGACGLFRVRLDGTVTAQDHDPQAVIAAFTARGDGVALIRERADRFPEVELNGLQVTALHRRLPFPTRTPRRVTFT
NELGEGEGWVLLPEGEGRAPALLSIHGGPHTAYGHAFMHEFQLFAARGYGVCYGNPRGSAGYGQAWTSAIHGRWGTVDMA
DLLAFFDACLAAEHRLDPRRTAVMGGSYGGYMTNWITGHTDRFQAAITDRSICNLISFGGTSDIGMRFWDDELGLNFHRS
EGALRLWDMSPLKYVENVRTPTLIIHSVLDHRCPIEQAEQWYTALKLHGVPVRFVRFPGEDHELSRSGRPDRRLRRLEEY
LEWLEEWVPGAAQQEQRTADTRA

Specific function: Involved In The Tonb-Independent Uptake Of Group A Colicins (Colicins A, E1, E2, E3 And K). Necessary For The Colicins To Reach Their Respective Targets After Initial Binding To The Bacteria. [C]

COG id: COG1506

COG function: function code E; Dipeptidyl aminopeptidases/acylaminoacyl-peptidases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9B family [H]

Homologues:

Organism=Homo sapiens, GI23510451, Length=226, Percent_Identity=30.9734513274336, Blast_Score=114, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI25149159, Length=225, Percent_Identity=25.7777777777778, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI25144540, Length=228, Percent_Identity=29.8245614035088, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI25144537, Length=228, Percent_Identity=29.8245614035088, Blast_Score=83, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17552908, Length=227, Percent_Identity=25.5506607929515, Blast_Score=80, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR011659
- InterPro:   IPR001375 [H]

Pfam domain/function: PF07676 PD40; PF00326 Peptidase_S9 [H]

EC number: NA

Molecular weight: Translated: 74465; Mature: 74334

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHSNPAMPGPESLLALAFPSDPQVSPDGQRVVFVLSRIEEEDPQRPDPAFARPRYKSQL
CCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEEHHHHHCCCCCCCCCCCCCCCCCEE
WLSGGGEAQPLTRGEGRDSSPRWSPDGQTLAFVREEGGQKGQLFLLPLTGGEAKRITRFR
EECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHHHH
GAVQDVQWSPDGRFLTFLSTADDEDRRDERGEARVITRPRYRFNGRDWLPERPARLWRYD
HHHHCCEECCCCCEEEEEECCCCCHHHHCCCCEEEEECCCEEECCCCCCCCCCHHHHHHH
VAAEELHEWLTPDVEVTGYAWWPDSRGVLLVSSRSEEDAAHWRQEANTLHLDGERTHLTR
HHHHHHHHHCCCCEEEEEEEECCCCCCEEEEECCCCHHHHHHHHCCCEEEECCCCEEEEH
WNSAIDAVIPHPDGQRFALVGRPEGKGSPEDHHLFLVGPDGAWQRLDEGWDRPIGNLVGG
HCCCCCEEECCCCCCEEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCHHCCCC
DCHVGAFPSRPVWLDAETLLVSSTVGGACGLFRVRLDGTVTAQDHDPQAVIAAFTARGDG
CEEECCCCCCCEEECCCEEEEECCCCCCEEEEEEEECCEEEECCCCCCEEEEEEECCCCC
VALIRERADRFPEVELNGLQVTALHRRLPFPTRTPRRVTFTNELGEGEGWVLLPEGEGRA
HHHHHHHHHCCCCEEECCEEEEEEHHCCCCCCCCCCEEEEECCCCCCCCEEEEECCCCCC
PALLSIHGGPHTAYGHAFMHEFQLFAARGYGVCYGNPRGSAGYGQAWTSAIHGRWGTVDM
CEEEEECCCCCCHHHHHHHHHHHHHEECCCEEEECCCCCCCCCCHHHHHHHCCCCCCCCH
ADLLAFFDACLAAEHRLDPRRTAVMGGSYGGYMTNWITGHTDRFQAAITDRSICNLISFG
HHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCEECCCCCCCHHHEEHHHHHHHHHHHHCC
GTSDIGMRFWDDELGLNFHRSEGALRLWDMSPLKYVENVRTPTLIIHSVLDHRCPIEQAE
CCCCCCCEEECHHCCCEEECCCCCEEEECCCHHHHHHHCCCHHHHHHHHHHCCCCHHHHH
QWYTALKLHGVPVRFVRFPGEDHELSRSGRPDRRLRRLEEYLEWLEEWVPGAAQQEQRTA
HHHHHHEECCCCEEEEECCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
DTRA
CCCC
>Mature Secondary Structure 
AHSNPAMPGPESLLALAFPSDPQVSPDGQRVVFVLSRIEEEDPQRPDPAFARPRYKSQL
CCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEEHHHHHCCCCCCCCCCCCCCCCCEE
WLSGGGEAQPLTRGEGRDSSPRWSPDGQTLAFVREEGGQKGQLFLLPLTGGEAKRITRFR
EECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHHHH
GAVQDVQWSPDGRFLTFLSTADDEDRRDERGEARVITRPRYRFNGRDWLPERPARLWRYD
HHHHCCEECCCCCEEEEEECCCCCHHHHCCCCEEEEECCCEEECCCCCCCCCCHHHHHHH
VAAEELHEWLTPDVEVTGYAWWPDSRGVLLVSSRSEEDAAHWRQEANTLHLDGERTHLTR
HHHHHHHHHCCCCEEEEEEEECCCCCCEEEEECCCCHHHHHHHHCCCEEEECCCCEEEEH
WNSAIDAVIPHPDGQRFALVGRPEGKGSPEDHHLFLVGPDGAWQRLDEGWDRPIGNLVGG
HCCCCCEEECCCCCCEEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCHHCCCC
DCHVGAFPSRPVWLDAETLLVSSTVGGACGLFRVRLDGTVTAQDHDPQAVIAAFTARGDG
CEEECCCCCCCEEECCCEEEEECCCCCCEEEEEEEECCEEEECCCCCCEEEEEEECCCCC
VALIRERADRFPEVELNGLQVTALHRRLPFPTRTPRRVTFTNELGEGEGWVLLPEGEGRA
HHHHHHHHHCCCCEEECCEEEEEEHHCCCCCCCCCCEEEEECCCCCCCCEEEEECCCCCC
PALLSIHGGPHTAYGHAFMHEFQLFAARGYGVCYGNPRGSAGYGQAWTSAIHGRWGTVDM
CEEEEECCCCCCHHHHHHHHHHHHHEECCCEEEECCCCCCCCCCHHHHHHHCCCCCCCCH
ADLLAFFDACLAAEHRLDPRRTAVMGGSYGGYMTNWITGHTDRFQAAITDRSICNLISFG
HHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCEECCCCCCCHHHEEHHHHHHHHHHHHCC
GTSDIGMRFWDDELGLNFHRSEGALRLWDMSPLKYVENVRTPTLIIHSVLDHRCPIEQAE
CCCCCCCEEECHHCCCEEECCCCCEEEECCCHHHHHHHCCCHHHHHHHHHHCCCCHHHHH
QWYTALKLHGVPVRFVRFPGEDHELSRSGRPDRRLRRLEEYLEWLEEWVPGAAQQEQRTA
HHHHHHEECCCCEEEEECCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
DTRA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 3098560 [H]