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The map label for this gene is citT [H]

Identifier: 94984462

GI number: 94984462

Start: 358420

End: 359073

Strand: Reverse

Name: citT [H]

Synonym: Dgeo_0354

Alternate gene names: 94984462

Gene position: 359073-358420 (Counterclockwise)

Preceding gene: 94984463

Following gene: 94984461

Centisome position: 14.55

GC content: 71.25

Gene sequence:

>654_bases
GTGACGTTCATCCGTACCCTGATTGTCGAGGACGACCCGCGCATCGCCAGGCTGCACCGCGGTCAGCTGGAAGGCGCCGG
GGACTTCGAGGTGCTGGGGACAGCGGAGACGCTGCAGGTGGCGCGGGTGATGGCAGAGACGCTTTGCCCCGACCTGCTGC
TGCTCGACGTGTATCTGCCCGACGGGCGCGGCCTGGACCTGCTGCGTGAGCTGCGGGCGCGCGGCCAGCGGGTGGACGCG
GTCCTCCTCACCGCCGCCAGCGACATTCCCAGTGTGCAGGAGGCACTGGCCCTGGGCGCGGCGGACTACCTGGTGAAACC
CTGCACGCCCGAACGCTTCGCTCTGGCCCTCGACCGGGTGCGTGAACGCTCCGCCCTGTGGCAGCAGGAGGCCGTACGGC
AGGGGCACCTCGACGCGCTGTTTGCCCGTCCCCCCCTGCCCGCTTCTGGCCTAGACCCGGAAACCCTCCACCGCGTCCGG
GCAACACTGCGGAGCGGCAGGGCCTACAGCGCGCGTGAACTCGGGCAGACCCTGGGCCTGAGCCGTGTCACCGCCTGGCG
GTACCTCGAGCACCTGGTCGAGGCGGGCGAGGCCTGCGCCGCAACAGACGTGCGCGGAATCGGGCGACCCGTCAAACGGT
ACCGGCGGGCGTGA

Upstream 100 bases:

>100_bases
TGCAGCGCCGTGCGGACGACCTCGGCGCGACGCTCACCCATGACCGGAGAGCCGACGCGACAGGCCAGCACTGGACCCGC
TTTACCCTGGAGGTGCCGCT

Downstream 100 bases:

>100_bases
CAGCGACAGGCTGTCCCTGCAACGGGAACGCGCCGCAGTTGGCCGGCGGGGTGGGTGGTAGGCTCGGGAGTGGTTATGGA
TGCTTACGACGTGTTGGTGA

Product: response regulator receiver/unknown domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MTFIRTLIVEDDPRIARLHRGQLEGAGDFEVLGTAETLQVARVMAETLCPDLLLLDVYLPDGRGLDLLRELRARGQRVDA
VLLTAASDIPSVQEALALGAADYLVKPCTPERFALALDRVRERSALWQQEAVRQGHLDALFARPPLPASGLDPETLHRVR
ATLRSGRAYSARELGQTLGLSRVTAWRYLEHLVEAGEACAATDVRGIGRPVKRYRRA

Sequences:

>Translated_217_residues
MTFIRTLIVEDDPRIARLHRGQLEGAGDFEVLGTAETLQVARVMAETLCPDLLLLDVYLPDGRGLDLLRELRARGQRVDA
VLLTAASDIPSVQEALALGAADYLVKPCTPERFALALDRVRERSALWQQEAVRQGHLDALFARPPLPASGLDPETLHRVR
ATLRSGRAYSARELGQTLGLSRVTAWRYLEHLVEAGEACAATDVRGIGRPVKRYRRA
>Mature_216_residues
TFIRTLIVEDDPRIARLHRGQLEGAGDFEVLGTAETLQVARVMAETLCPDLLLLDVYLPDGRGLDLLRELRARGQRVDAV
LLTAASDIPSVQEALALGAADYLVKPCTPERFALALDRVRERSALWQQEAVRQGHLDALFARPPLPASGLDPETLHRVRA
TLRSGRAYSARELGQTLGLSRVTAWRYLEHLVEAGEACAATDVRGIGRPVKRYRRA

Specific function: Member of the two-component regulatory system CitT/CitS. Regulates the expression of the citM-yflN operon. Phosphorylated CitT binds to the citM promoter to activate the transcription of the citM-yflN operon [H]

COG id: COG4565

COG function: function code KT; Response regulator of citrate/malate metabolism

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786838, Length=218, Percent_Identity=37.1559633027523, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790566, Length=225, Percent_Identity=32.4444444444444, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786911, Length=106, Percent_Identity=44.3396226415094, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR013196
- InterPro:   IPR001789 [H]

Pfam domain/function: PF08279 HTH_11; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23983; Mature: 23852

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFIRTLIVEDDPRIARLHRGQLEGAGDFEVLGTAETLQVARVMAETLCPDLLLLDVYLP
CCHHEEEEECCCCHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCHHEEEEEECC
DGRGLDLLRELRARGQRVDAVLLTAASDIPSVQEALALGAADYLVKPCTPERFALALDRV
CCCCHHHHHHHHHCCCHHHHHEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RERSALWQQEAVRQGHLDALFARPPLPASGLDPETLHRVRATLRSGRAYSARELGQTLGL
HHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCH
SRVTAWRYLEHLVEAGEACAATDVRGIGRPVKRYRRA
HHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHCC
>Mature Secondary Structure 
TFIRTLIVEDDPRIARLHRGQLEGAGDFEVLGTAETLQVARVMAETLCPDLLLLDVYLP
CHHEEEEECCCCHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCHHEEEEEECC
DGRGLDLLRELRARGQRVDAVLLTAASDIPSVQEALALGAADYLVKPCTPERFALALDRV
CCCCHHHHHHHHHCCCHHHHHEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
RERSALWQQEAVRQGHLDALFARPPLPASGLDPETLHRVRATLRSGRAYSARELGQTLGL
HHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCH
SRVTAWRYLEHLVEAGEACAATDVRGIGRPVKRYRRA
HHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377; 10972810 [H]