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The map label for this gene is ldh [H]

Identifier: 94984311

GI number: 94984311

Start: 188222

End: 189256

Strand: Reverse

Name: ldh [H]

Synonym: Dgeo_0203

Alternate gene names: 94984311

Gene position: 189256-188222 (Counterclockwise)

Preceding gene: 94984315

Following gene: 94984310

Centisome position: 7.67

GC content: 70.14

Gene sequence:

>1035_bases
ATGCAGATATTCGAGGAGATGCAATCACGCGGGCACGAGGCCCTGACGCTACTCCACCACGCCCCCAGCGGGCTTAAGGC
AGCACTGGCCGTGCATTCAACCGTGCTGGGTCCCGCCATCGCCGGGGTGCGCCTGCGCCCGATGGACGAGCAGGAGGCGC
TGCGAAGTGCCCTGACCCTCAGCGAGAGCCTCACGCTCAAGGCGGCGCTCGCGGGCCTGAACTACGGTGGGGGCGCTTGT
GTGCTGCTGATGCCCGAAACCGGTGTGGACGACCCGCATGCCCGCGAGGCGCTGTTTCGCGCGCTGGGGCGCAAGGTCCG
GCCCCTCCAGTCTCTGGTCGTGCTGACCGAGGACATCGGCGTGACGCCGAGTGACATCGCCTTTGTGGCGCAGGAGACAC
CTGCCACCCTGGGCGTCAACACCGACACCAGCAGCGTGACCGGCTACGGCGTGTACCGGGGGATGAAGGCCGCCGCCCGT
TCTGCCTTGGGCAGCGAGAGCATGCGCGGTGTGCGGGTGGCGATTCTGGGCGTGGGCGCGGTGGGCCGCACGCTCGCCGA
ATACCTGCACCGCGAAGGCGCCCGCCTCACCGTCGCGGACGAGCGGCCCGAGCGGGCCGAGGCGCTGGCGGACGACCTCG
ACGGCGTGACCGTGGTGGGCGCGCAGGACCTGCTCGACGTGCCCTGCGACATCCTCTCGCCCTGCGGCTACGGCCACTCC
GTCCACAGCGCCGACGTGCCGAGGTTGCAGTGCCGCCTGATCGCGGGCGGCGAGCACCATCCCCTCTCCCGCCGGGGCGA
AGACGCCGTCAAAGAAGCCGGGATCATGTATATCCCCGACTTCGCGATCAACGCGGCGGGCCTGATCGCCGCCGCGAGCA
CGCTCACCCCCGAACAGGCCGCCGAGCGGGTCTACAGCACCGTGAGTCGCATCGTCCATATCGCCGAACAGGTCGGCAAG
CCGCCGCATGTGGTCGCACGGCGCATGGCGGAACGGCGGATCGACCTGATCGGCAGTCTGGGACGGGGCGCGTGA

Upstream 100 bases:

>100_bases
ATGAGCGTGTTCCCGGCGCCTGAATCCCGGCGCCCAAATGCTATCTTGTGAGGGTTGCCGCGCCGCGCCGCGCCGGAGGG
GAGCGGGCACCAGGAGAACG

Downstream 100 bases:

>100_bases
GGCGGAAAAGGCCCGTGGAGCGGCGGTCTGTCTTGGCCCACTTCCCCCTCACCACTTCCCACTCACCGCGCGGGGGGCGC
ACATGACCGCTCCCTTTGTC

Product: Glu/Leu/Phe/Val dehydrogenase

Products: NA

Alternate protein names: LeuDH [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MQIFEEMQSRGHEALTLLHHAPSGLKAALAVHSTVLGPAIAGVRLRPMDEQEALRSALTLSESLTLKAALAGLNYGGGAC
VLLMPETGVDDPHAREALFRALGRKVRPLQSLVVLTEDIGVTPSDIAFVAQETPATLGVNTDTSSVTGYGVYRGMKAAAR
SALGSESMRGVRVAILGVGAVGRTLAEYLHREGARLTVADERPERAEALADDLDGVTVVGAQDLLDVPCDILSPCGYGHS
VHSADVPRLQCRLIAGGEHHPLSRRGEDAVKEAGIMYIPDFAINAAGLIAAASTLTPEQAAERVYSTVSRIVHIAEQVGK
PPHVVARRMAERRIDLIGSLGRGA

Sequences:

>Translated_344_residues
MQIFEEMQSRGHEALTLLHHAPSGLKAALAVHSTVLGPAIAGVRLRPMDEQEALRSALTLSESLTLKAALAGLNYGGGAC
VLLMPETGVDDPHAREALFRALGRKVRPLQSLVVLTEDIGVTPSDIAFVAQETPATLGVNTDTSSVTGYGVYRGMKAAAR
SALGSESMRGVRVAILGVGAVGRTLAEYLHREGARLTVADERPERAEALADDLDGVTVVGAQDLLDVPCDILSPCGYGHS
VHSADVPRLQCRLIAGGEHHPLSRRGEDAVKEAGIMYIPDFAINAAGLIAAASTLTPEQAAERVYSTVSRIVHIAEQVGK
PPHVVARRMAERRIDLIGSLGRGA
>Mature_344_residues
MQIFEEMQSRGHEALTLLHHAPSGLKAALAVHSTVLGPAIAGVRLRPMDEQEALRSALTLSESLTLKAALAGLNYGGGAC
VLLMPETGVDDPHAREALFRALGRKVRPLQSLVVLTEDIGVTPSDIAFVAQETPATLGVNTDTSSVTGYGVYRGMKAAAR
SALGSESMRGVRVAILGVGAVGRTLAEYLHREGARLTVADERPERAEALADDLDGVTVVGAQDLLDVPCDILSPCGYGHS
VHSADVPRLQCRLIAGGEHHPLSRRGEDAVKEAGIMYIPDFAINAAGLIAAASTLTPEQAAERVYSTVSRIVHIAEQVGK
PPHVVARRMAERRIDLIGSLGRGA

Specific function: Functions catabolically in the bacterial metabolism of branched-chain L-amino acids. Catalyzes the reversible deamination of these branched-chain L-amino acids to their oxo analogs [H]

COG id: COG0334

COG function: function code E; Glutamate dehydrogenase/leucine dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Glu/Leu/Phe/Val dehydrogenases family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006095
- InterPro:   IPR006096
- InterPro:   IPR006097
- InterPro:   IPR016211
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00208 ELFV_dehydrog; PF02812 ELFV_dehydrog_N [H]

EC number: =1.4.1.9 [H]

Molecular weight: Translated: 36256; Mature: 36256

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIFEEMQSRGHEALTLLHHAPSGLKAALAVHSTVLGPAIAGVRLRPMDEQEALRSALTL
CCHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHH
SESLTLKAALAGLNYGGGACVLLMPETGVDDPHAREALFRALGRKVRPLQSLVVLTEDIG
HHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHCCC
VTPSDIAFVAQETPATLGVNTDTSSVTGYGVYRGMKAAARSALGSESMRGVRVAILGVGA
CCHHHHEEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHCCCEEEEEEECCH
VGRTLAEYLHREGARLTVADERPERAEALADDLDGVTVVGAQDLLDVPCDILSPCGYGHS
HHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCCEEEECCHHHHHCCHHHHCCCCCCCC
VHSADVPRLQCRLIAGGEHHPLSRRGEDAVKEAGIMYIPDFAINAAGLIAAASTLTPEQA
CCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHCCCEEECCHHHCHHHHHHHHHCCCHHHH
AERVYSTVSRIVHIAEQVGKPPHVVARRMAERRIDLIGSLGRGA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQIFEEMQSRGHEALTLLHHAPSGLKAALAVHSTVLGPAIAGVRLRPMDEQEALRSALTL
CCHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHH
SESLTLKAALAGLNYGGGACVLLMPETGVDDPHAREALFRALGRKVRPLQSLVVLTEDIG
HHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHCCC
VTPSDIAFVAQETPATLGVNTDTSSVTGYGVYRGMKAAARSALGSESMRGVRVAILGVGA
CCHHHHEEEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHCCCEEEEEEECCH
VGRTLAEYLHREGARLTVADERPERAEALADDLDGVTVVGAQDLLDVPCDILSPCGYGHS
HHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCCEEEECCHHHHHCCHHHHCCCCCCCC
VHSADVPRLQCRLIAGGEHHPLSRRGEDAVKEAGIMYIPDFAINAAGLIAAASTLTPEQA
CCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHCCCEEECCHHHCHHHHHHHHHCCCHHHH
AERVYSTVSRIVHIAEQVGKPPHVVARRMAERRIDLIGSLGRGA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8020469 [H]