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The map label for this gene is xylR [H]

Identifier: 94972150

GI number: 94972150

Start: 345838

End: 347040

Strand: Direct

Name: xylR [H]

Synonym: Dgeo_2683

Alternate gene names: 94972150

Gene position: 345838-347040 (Clockwise)

Preceding gene: 94972152

Following gene: 94972148

Centisome position: 60.24

GC content: 66.0

Gene sequence:

>1203_bases
ATGACCTCAGTGCCTATCCATGCCCGCGCCGGAGACCAGGGTTTCCTCAAGCAGCTCAATCGGTCGGCCGTTCTGGAGTT
GATTCGGCGCGAGCCGGGCATCTCCCGGGCAGAACTGGCCGCGCGCACCCAACTCACCAAGGTCACCGTCGGCGCGATGG
TCCAGGAACTGCTGGATCAGGGCTGGTTGGTCGAGGGGAGTTTGCAGCAGGGAAGCCTCGGACGTCCGGGGCGTGCCCTG
CACCTCAACGAACGGCGGCATGTTCTGCTGGGTGCGGAGGTTGGCGTCCAGGGCCTGCGGGTGGTGGCCTGCACATTGAC
CGGCCGGGCCCTTGGGCAGCGCGCTATCCTCGTCCCCTCGACCACTCCCGAGGCCACCGCCCAGCATCTGGCTACCCTGA
TTATGGAAGTGCTGACCTATCCCGAGGTGGCGGGCCGGGAGGTGCTGGGCCTGGGGGTGGCAGTCCCGGGGCCCGTGGCG
CTCCACGATCCCACCCTGCTGTTCGCCCCGAACCTGGGCTGGCGCGACGTGCCCTTCCTCACGGTCCTGAAGCCATTCCT
GCCTGATCTACCCGGGCCCTGGCTGCTCGAAAACGAGGCGAAGGCCGCCGCGTTCGGGGAGGTTTACTTCTCCGGGGGAG
ACAAGCCGGAACTGCTGGCCTACCTGAGCCTGGGGACGGGCATCGGCAGTGGCCTTATGGTAGGCGCCCCCGTCCCTTAC
CTGTTGCGTGGCGCCCAGGGTCTGGCGGGTGAGATCGGGCATTCCGTGCTGCAATCAGGAGGACTGTATTGTCACTGCGG
GAACCGCGGCTGTGCCGAAACCCTGGTCAGCGGCTGGGCCATTCGCGCCGCGCTGGACATTCCCCCCGGCGTCCCCCTAG
AGCCCGCCCTCCAGCCCCGCATGCAGGATGCGGACGTGCAGGTCACCCTTCGGCGCGCAGGGGAAGCGTTGGGGATGCTC
CTGACGAACCTACACCACACCCTCAACCCCAGTGACATCGTGCTCGGGGGCTCACTGACCCGCCTGGGTGAACCGCTACT
TGGGCCCGCGCTAGCCTTCTTTAGGGAGCACCAACATGACCTGTATACCCGTACAGCATCGATCAGCATTCACATCCGTA
CGGACAGCACCTTCCTTCCAGCACGCGGGGCTGCAGCACAAGTTCTGGCCAGCGTTTTTCACGAGTCGAGTGTCTTGGGT
TGA

Upstream 100 bases:

>100_bases
GGCCTAAGATGTCCCCCATGTTTGTAATCTCCACTTACTTAACAACCACCAGTTTCCGCCGTGACCGCCTCAGTTCTCGT
GCTCCTGGGAAGATACGCGT

Downstream 100 bases:

>100_bases
GGTCAAACTTGCACCTAAATGGGTAGCGAAAAGGCGCTCCCGGACGCGAGAAAGAGGGGATGTGGAACCTCAAGCTTCGC
GGGGAGCGCGCGTCCATTCT

Product: ROK domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MTSVPIHARAGDQGFLKQLNRSAVLELIRREPGISRAELAARTQLTKVTVGAMVQELLDQGWLVEGSLQQGSLGRPGRAL
HLNERRHVLLGAEVGVQGLRVVACTLTGRALGQRAILVPSTTPEATAQHLATLIMEVLTYPEVAGREVLGLGVAVPGPVA
LHDPTLLFAPNLGWRDVPFLTVLKPFLPDLPGPWLLENEAKAAAFGEVYFSGGDKPELLAYLSLGTGIGSGLMVGAPVPY
LLRGAQGLAGEIGHSVLQSGGLYCHCGNRGCAETLVSGWAIRAALDIPPGVPLEPALQPRMQDADVQVTLRRAGEALGML
LTNLHHTLNPSDIVLGGSLTRLGEPLLGPALAFFREHQHDLYTRTASISIHIRTDSTFLPARGAAAQVLASVFHESSVLG

Sequences:

>Translated_400_residues
MTSVPIHARAGDQGFLKQLNRSAVLELIRREPGISRAELAARTQLTKVTVGAMVQELLDQGWLVEGSLQQGSLGRPGRAL
HLNERRHVLLGAEVGVQGLRVVACTLTGRALGQRAILVPSTTPEATAQHLATLIMEVLTYPEVAGREVLGLGVAVPGPVA
LHDPTLLFAPNLGWRDVPFLTVLKPFLPDLPGPWLLENEAKAAAFGEVYFSGGDKPELLAYLSLGTGIGSGLMVGAPVPY
LLRGAQGLAGEIGHSVLQSGGLYCHCGNRGCAETLVSGWAIRAALDIPPGVPLEPALQPRMQDADVQVTLRRAGEALGML
LTNLHHTLNPSDIVLGGSLTRLGEPLLGPALAFFREHQHDLYTRTASISIHIRTDSTFLPARGAAAQVLASVFHESSVLG
>Mature_399_residues
TSVPIHARAGDQGFLKQLNRSAVLELIRREPGISRAELAARTQLTKVTVGAMVQELLDQGWLVEGSLQQGSLGRPGRALH
LNERRHVLLGAEVGVQGLRVVACTLTGRALGQRAILVPSTTPEATAQHLATLIMEVLTYPEVAGREVLGLGVAVPGPVAL
HDPTLLFAPNLGWRDVPFLTVLKPFLPDLPGPWLLENEAKAAAFGEVYFSGGDKPELLAYLSLGTGIGSGLMVGAPVPYL
LRGAQGLAGEIGHSVLQSGGLYCHCGNRGCAETLVSGWAIRAALDIPPGVPLEPALQPRMQDADVQVTLRRAGEALGMLL
TNLHHTLNPSDIVLGGSLTRLGEPLLGPALAFFREHQHDLYTRTASISIHIRTDSTFLPARGAAAQVLASVFHESSVLG

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=269, Percent_Identity=27.5092936802974, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI298566325, Length=269, Percent_Identity=27.5092936802974, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI4885285, Length=269, Percent_Identity=27.5092936802974, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI190014632, Length=269, Percent_Identity=27.5092936802974, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1786891, Length=362, Percent_Identity=23.7569060773481, Blast_Score=99, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 42353; Mature: 42221

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSVPIHARAGDQGFLKQLNRSAVLELIRREPGISRAELAARTQLTKVTVGAMVQELLDQ
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
GWLVEGSLQQGSLGRPGRALHLNERRHVLLGAEVGVQGLRVVACTLTGRALGQRAILVPS
CCEEECCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCEEEEEEEECCHHHCCEEEEECC
TTPEATAQHLATLIMEVLTYPEVAGREVLGLGVAVPGPVALHDPTLLFAPNLGWRDVPFL
CCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCEEECCCEEEEECCCCCCCCCHH
TVLKPFLPDLPGPWLLENEAKAAAFGEVYFSGGDKPELLAYLSLGTGIGSGLMVGAPVPY
HHHHHHHCCCCCCCEECCCCCHHEEEEEEECCCCCCCEEEEEECCCCCCCCCEECCCHHH
LLRGAQGLAGEIGHSVLQSGGLYCHCGNRGCAETLVSGWAIRAALDIPPGVPLEPALQPR
HHHCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHCCCEEEEEEECCCCCCCCCCCCCC
MQDADVQVTLRRAGEALGMLLTNLHHTLNPSDIVLGGSLTRLGEPLLGPALAFFREHQHD
CCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHCCCHHHHHHHHHHHHHHH
LYTRTASISIHIRTDSTFLPARGAAAQVLASVFHESSVLG
HHEEEEEEEEEEEECCEECCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TSVPIHARAGDQGFLKQLNRSAVLELIRREPGISRAELAARTQLTKVTVGAMVQELLDQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
GWLVEGSLQQGSLGRPGRALHLNERRHVLLGAEVGVQGLRVVACTLTGRALGQRAILVPS
CCEEECCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCEEEEEEEECCHHHCCEEEEECC
TTPEATAQHLATLIMEVLTYPEVAGREVLGLGVAVPGPVALHDPTLLFAPNLGWRDVPFL
CCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCEEECCCEEEEECCCCCCCCCHH
TVLKPFLPDLPGPWLLENEAKAAAFGEVYFSGGDKPELLAYLSLGTGIGSGLMVGAPVPY
HHHHHHHCCCCCCCEECCCCCHHEEEEEEECCCCCCCEEEEEECCCCCCCCCEECCCHHH
LLRGAQGLAGEIGHSVLQSGGLYCHCGNRGCAETLVSGWAIRAALDIPPGVPLEPALQPR
HHHCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHCCCEEEEEEECCCCCCCCCCCCCC
MQDADVQVTLRRAGEALGMLLTNLHHTLNPSDIVLGGSLTRLGEPLLGPALAFFREHQHD
CCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHCCCHHHHHHHHHHHHHHH
LYTRTASISIHIRTDSTFLPARGAAAQVLASVFHESSVLG
HHEEEEEEEEEEEECCEECCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544559 [H]