Click here to switch to the map view.

The map label for this gene is ycbL [H]

Identifier: 94972148

GI number: 94972148

Start: 348002

End: 349396

Strand: Direct

Name: ycbL [H]

Synonym: Dgeo_2681

Alternate gene names: 94972148

Gene position: 348002-349396 (Clockwise)

Preceding gene: 94972150

Following gene: 94972147

Centisome position: 60.61

GC content: 65.73

Gene sequence:

>1395_bases
ATGTTCTTCAAACGCTTCTACGACACGGACCTCGCGCAGGCCTCCTACATGATCGGCTGCCAGCAGACCGGCGAATGCCT
GGTCGTTGACCCCATCCGGGATATTCAGCAGTACCTCGACGAGGCCAAGAGCCAGAAGCTGCGCGTCACCCACGTCACCG
AGACGCACATCCACGCCGACTACCTCTCGGGCAGCCGCGAGCTGGCAAAGGCCACGGGCGCGAAGCTGCTGCTCTCGGAC
GAGGGCGGCGAGGGCTGGCGTTATACCTACGACGACGGGAACCAGATACGGCTGCACGACGGCGACACCTTCATGGTGGG
CAACGTCCGGATCGATGTGCTGCATACGCCCGGCCACACGCCGGAGCATCTGAGCTTCCTGGTCACCGATACCCCCCGGG
GCGATACCCCCTCAATGATCCTGACCGGCGACTTCGTGTTTGTCGGCGACCTGGGCCGCCCCGACCTGCTCGACGAGGCA
GCGGGCGGTCAGGACACCCGGTTTGTGGGCGCGAAGCAAATGTTCGCCTCGCTGCGTGACAAGTTCCTGTCCCTGCCCGA
CTACGTGCAGGTGTGGCCCGGCCACGGCGCCGGCAGTGCTTGCGGCAAAGCGCTGGGCGCAGTCCCCACAACCACGGTGG
GGTACGAGCGGGCGCTGAGCTGGTGGGGCAAGCTCGTCGAGAAGGGCGACGAAGAGGCCTTTACCCAAGAATTGCTGAGC
GGCCAGCCCGACGCGCCGCTGTACTACGGGCGCATGAAGCGGGAAAACCGCGACGGTCCGGCTCTGCTGGGCGAGGTGCA
GGCCTTGCCTGAGCTGAGTGTCAAGGACGTGCAGGCGTGGCTTGCGGCCGGAGCCCGACTCATCGACACCCGCAGAAAAG
AGGAACACCAGGCCGCCGCGCCTGTAGGCAGCATCAACATCCCCGACGGCAACACCTTTGAGACCTGGGCCGGATGGCTG
CTCAAGCCAGAACGAGCCTTTATCCTGTTGGCCCCCGCTCACCGTGCCGAGGTGCTGCGCCGCCGGCTGTGGATGGTGGG
CCTCGACAACGTGATTGGCTTTATTCCCAGCGCCGAGGGGCTGGAGACAGCACCCGCCCAGCCCATCCCGGCGAGCGAAC
TTCCCCAACACGAGGACGCCCTGATTCTCGATGTACGGGCGAAAACTGAGTATGAGCGCGGGCATATCCCCGGTGCCCAC
CAACTGCACGCCGGACGCCTTCCTTGGCGCCTCAGCACCCTGCCGCGTGACCGCGAGATCGTGGTGCATTGCCAGGGAGG
CGCCCGGAGCGCTGCCGCTGCCAGCCTGCTCCGTGCCGAGGGCTTCCAGGTCACCGAACTTGCCGGTGGCTATGACGCCT
GGGCCAAAACCCAACAAGAAACCCTACCCGCGTAA

Upstream 100 bases:

>100_bases
GCGCTCAGAATAAGCTTTATTGGAATTTCCAATAAGTCACGCGAGATTATTGCTCTTATACCTCCGAGGGGTATACCTTC
AAGCCAACCAAGGAGGGACC

Downstream 100 bases:

>100_bases
CCCGCAATCGACGGGGGGCGGACCTCAGCGCCGCCCCCGATTTTCTTGAAAGGAGGGTGCTATGCCCTATCAGGACATCT
TTCCCAATGAACTCGAAGCC

Product: beta-lactamase-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MFFKRFYDTDLAQASYMIGCQQTGECLVVDPIRDIQQYLDEAKSQKLRVTHVTETHIHADYLSGSRELAKATGAKLLLSD
EGGEGWRYTYDDGNQIRLHDGDTFMVGNVRIDVLHTPGHTPEHLSFLVTDTPRGDTPSMILTGDFVFVGDLGRPDLLDEA
AGGQDTRFVGAKQMFASLRDKFLSLPDYVQVWPGHGAGSACGKALGAVPTTTVGYERALSWWGKLVEKGDEEAFTQELLS
GQPDAPLYYGRMKRENRDGPALLGEVQALPELSVKDVQAWLAAGARLIDTRRKEEHQAAAPVGSINIPDGNTFETWAGWL
LKPERAFILLAPAHRAEVLRRRLWMVGLDNVIGFIPSAEGLETAPAQPIPASELPQHEDALILDVRAKTEYERGHIPGAH
QLHAGRLPWRLSTLPRDREIVVHCQGGARSAAAASLLRAEGFQVTELAGGYDAWAKTQQETLPA

Sequences:

>Translated_464_residues
MFFKRFYDTDLAQASYMIGCQQTGECLVVDPIRDIQQYLDEAKSQKLRVTHVTETHIHADYLSGSRELAKATGAKLLLSD
EGGEGWRYTYDDGNQIRLHDGDTFMVGNVRIDVLHTPGHTPEHLSFLVTDTPRGDTPSMILTGDFVFVGDLGRPDLLDEA
AGGQDTRFVGAKQMFASLRDKFLSLPDYVQVWPGHGAGSACGKALGAVPTTTVGYERALSWWGKLVEKGDEEAFTQELLS
GQPDAPLYYGRMKRENRDGPALLGEVQALPELSVKDVQAWLAAGARLIDTRRKEEHQAAAPVGSINIPDGNTFETWAGWL
LKPERAFILLAPAHRAEVLRRRLWMVGLDNVIGFIPSAEGLETAPAQPIPASELPQHEDALILDVRAKTEYERGHIPGAH
QLHAGRLPWRLSTLPRDREIVVHCQGGARSAAAASLLRAEGFQVTELAGGYDAWAKTQQETLPA
>Mature_464_residues
MFFKRFYDTDLAQASYMIGCQQTGECLVVDPIRDIQQYLDEAKSQKLRVTHVTETHIHADYLSGSRELAKATGAKLLLSD
EGGEGWRYTYDDGNQIRLHDGDTFMVGNVRIDVLHTPGHTPEHLSFLVTDTPRGDTPSMILTGDFVFVGDLGRPDLLDEA
AGGQDTRFVGAKQMFASLRDKFLSLPDYVQVWPGHGAGSACGKALGAVPTTTVGYERALSWWGKLVEKGDEEAFTQELLS
GQPDAPLYYGRMKRENRDGPALLGEVQALPELSVKDVQAWLAAGARLIDTRRKEEHQAAAPVGSINIPDGNTFETWAGWL
LKPERAFILLAPAHRAEVLRRRLWMVGLDNVIGFIPSAEGLETAPAQPIPASELPQHEDALILDVRAKTEYERGHIPGAH
QLHAGRLPWRLSTLPRDREIVVHCQGGARSAAAASLLRAEGFQVTELAGGYDAWAKTQQETLPA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=202, Percent_Identity=26.2376237623762, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1787158, Length=230, Percent_Identity=29.1304347826087, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17538952, Length=198, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI221330176, Length=201, Percent_Identity=24.3781094527363, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24667703, Length=184, Percent_Identity=28.2608695652174, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 51019; Mature: 51019

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS00380 RHODANESE_1 ; PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFKRFYDTDLAQASYMIGCQQTGECLVVDPIRDIQQYLDEAKSQKLRVTHVTETHIHAD
CCCHHHHCCHHHHHHEEEECCCCCCEEEECCHHHHHHHHHHHHCCCEEEEEEEEHHEEHH
YLSGSRELAKATGAKLLLSDEGGEGWRYTYDDGNQIRLHDGDTFMVGNVRIDVLHTPGHT
HHCCCHHHHHHCCCEEEEECCCCCCCEEEECCCCEEEEECCCEEEECCEEEEEEECCCCC
PEHLSFLVTDTPRGDTPSMILTGDFVFVGDLGRPDLLDEAAGGQDTRFVGAKQMFASLRD
CCCEEEEEECCCCCCCCCEEEEECEEEEECCCCCCHHHHCCCCCCCEEHHHHHHHHHHHH
KFLSLPDYVQVWPGHGAGSACGKALGAVPTTTVGYERALSWWGKLVEKGDEEAFTQELLS
HHCCCCCCEEEECCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
GQPDAPLYYGRMKRENRDGPALLGEVQALPELSVKDVQAWLAAGARLIDTRRKEEHQAAA
CCCCCCEEECHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHC
PVGSINIPDGNTFETWAGWLLKPERAFILLAPAHRAEVLRRRLWMVGLDNVIGFIPSAEG
CCCEEECCCCCCHHHHHCCEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LETAPAQPIPASELPQHEDALILDVRAKTEYERGHIPGAHQLHAGRLPWRLSTLPRDREI
CCCCCCCCCCHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEE
VVHCQGGARSAAAASLLRAEGFQVTELAGGYDAWAKTQQETLPA
EEEECCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHCHHHCCCC
>Mature Secondary Structure
MFFKRFYDTDLAQASYMIGCQQTGECLVVDPIRDIQQYLDEAKSQKLRVTHVTETHIHAD
CCCHHHHCCHHHHHHEEEECCCCCCEEEECCHHHHHHHHHHHHCCCEEEEEEEEHHEEHH
YLSGSRELAKATGAKLLLSDEGGEGWRYTYDDGNQIRLHDGDTFMVGNVRIDVLHTPGHT
HHCCCHHHHHHCCCEEEEECCCCCCCEEEECCCCEEEEECCCEEEECCEEEEEEECCCCC
PEHLSFLVTDTPRGDTPSMILTGDFVFVGDLGRPDLLDEAAGGQDTRFVGAKQMFASLRD
CCCEEEEEECCCCCCCCCEEEEECEEEEECCCCCCHHHHCCCCCCCEEHHHHHHHHHHHH
KFLSLPDYVQVWPGHGAGSACGKALGAVPTTTVGYERALSWWGKLVEKGDEEAFTQELLS
HHCCCCCCEEEECCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
GQPDAPLYYGRMKRENRDGPALLGEVQALPELSVKDVQAWLAAGARLIDTRRKEEHQAAA
CCCCCCEEECHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHC
PVGSINIPDGNTFETWAGWLLKPERAFILLAPAHRAEVLRRRLWMVGLDNVIGFIPSAEG
CCCEEECCCCCCHHHHHCCEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LETAPAQPIPASELPQHEDALILDVRAKTEYERGHIPGAHQLHAGRLPWRLSTLPRDREI
CCCCCCCCCCHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEE
VVHCQGGARSAAAASLLRAEGFQVTELAGGYDAWAKTQQETLPA
EEEECCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]