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The map label for this gene is glpD2 [H]

Identifier: 94971989

GI number: 94971989

Start: 525981

End: 527540

Strand: Direct

Name: glpD2 [H]

Synonym: Dgeo_2521

Alternate gene names: 94971989

Gene position: 525981-527540 (Clockwise)

Preceding gene: 94971990

Following gene: 94971987

Centisome position: 91.61

GC content: 68.65

Gene sequence:

>1560_bases
ATGCTCCAAGATCCCCGCTCGGCTATCCTCGCCGCCGCCACCGCCCCCGGAACCTGGGACGTTCTCGTGATTGGGGGCGG
CGCGTCTGGCCTAGGTACCGCCGTAGAGGCCGCCACGCGCGGCCACCGTACCCTGCTGCTCGAAGGCCATGACTACGCCA
AGGGCACCAGCAGCCGCTCCACCAAACTCGTTCATGGGGGCGTGCGTTATCTCGCACAGGGAAATGTCAGCCTGGTGCGC
GAGGCGCTCCACGAGCGCGGCCTGCTGCGCAAGAACGCGCCCCATCTCACGCGCAACCTGAGCTTTGTGGTCCCCGCCTA
TGACTGGTGGGCGGGTCCCTTTTATGGGATTGGCCTGAAACTGTATGACATCCTGGCTGGGCGATTGAACCTGGGGAGCA
GCAAGTACCTGGGCAAAGAGGCTGCTCTGGAACGCACACCTACCCTCCAAGCGGAGGGCCTGATGGGCGGCATCCTGTAC
TTCGACGGCCAGTTCGACGACGCCCGGCTGGCTGTGACGCTGCTGCGGACGCTGGAAGACCACGGCGGGGTGGCGCTCAA
CTATGCTCCCGTCACCGGGCTGATTCAGGAAAACGGCAAGGTGGTGGGCGCCCGCTTCCGCGACCTGGAAACGGGCCAGG
CGTACGCGGCGCGGGCGCGGGTGGTGGTGAACGCGACGGGCGTGTGGGTGGATGACATCCGCCGCATGGAGAACCCGGAC
GCAAAGCCGATGCTCTCCCCCAGCCAGGGGTCACACGTGGTCGTGGAGAAACGCTTTCTGCCCGGCGACAGCGCCATCAT
GATCCCGCGCACCGACGACGGGCGGGTGCTGTTCGCGGTGCCCTGGCATGACCATGTGGTGATCGGCACCACCGATCTCC
CCGTTCCCAGCACCCCCTTCGAGCCGCGCCCGCTGGAAGAGGAGATCGAGTTCATCCTGAAGACCGCCGCGCGCTACCTG
GACCCGGCCCCCACCCGTGCGGACGTGCGCAGCGTGTACGCTGGCTTGCGACCCCTGGTCAAAAACGAGCGGACCGACGG
CGCCGGCTCGACGGCAGCGCTCTCGCGCGACCACGTGATTCGCATCTCGGATGGTGGCCTGGTCACACTGACGGGTGGCA
AGTGGACGACCTATCGCCGTATGGGTGAGGACACCGTGAACCGTGCAGAGCAGGTGGGCGGTCTGTCTGGGCGCCTCACG
GTCACCCCCGGCCTGCACCTGCACGGCTGGTCGGAAGAACCCCGCCCCGATCCGCTCAGGGTCTACGGCAGCGATGCCGA
GCGGATCAGGGCCCTGCCCGGCGCCGACCGCCTCCTCCACCCCGAACTCCCCTACACCGAGGCCGAGCTGCGCTGGGGCG
TCCGCTTCGAGAGTGCGCGCACGGTGGAGGACCTGCTCGCCCGGCGGACCCGCGCCCTGCTGCTGCATGCCCGCGCCAGC
ATCGAGGCGGCACCTCGCGCCGCCGCCATCCTCGCGGAAGAACTGGGCCGAGACCAGGCGTGGGCCGAGGAGCAGGTGCG
GCGCTACGAGGAGGTCGCGCGGGGCTACGTGCTGGCGTGA

Upstream 100 bases:

>100_bases
AAGGACTCGCTCAAGATGACTCGCCAGTGGACATTCGTTCATACTAGGTGAACATTCGTTCGGATGTGTAGTGCCTCTCC
GTTCAGAAAGGATTTTCCTG

Downstream 100 bases:

>100_bases
GGGTGGCCCCCCTGCTCCCAGTTGTGCACTACCCGTTGTGCATGGACTCCCGCAAGATGCCTTCCAGGTCTTGCGCCGTC
GGGGTCCGGGGCGCGACGGC

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 519; Mature: 519

Protein sequence:

>519_residues
MLQDPRSAILAAATAPGTWDVLVIGGGASGLGTAVEAATRGHRTLLLEGHDYAKGTSSRSTKLVHGGVRYLAQGNVSLVR
EALHERGLLRKNAPHLTRNLSFVVPAYDWWAGPFYGIGLKLYDILAGRLNLGSSKYLGKEAALERTPTLQAEGLMGGILY
FDGQFDDARLAVTLLRTLEDHGGVALNYAPVTGLIQENGKVVGARFRDLETGQAYAARARVVVNATGVWVDDIRRMENPD
AKPMLSPSQGSHVVVEKRFLPGDSAIMIPRTDDGRVLFAVPWHDHVVIGTTDLPVPSTPFEPRPLEEEIEFILKTAARYL
DPAPTRADVRSVYAGLRPLVKNERTDGAGSTAALSRDHVIRISDGGLVTLTGGKWTTYRRMGEDTVNRAEQVGGLSGRLT
VTPGLHLHGWSEEPRPDPLRVYGSDAERIRALPGADRLLHPELPYTEAELRWGVRFESARTVEDLLARRTRALLLHARAS
IEAAPRAAAILAEELGRDQAWAEEQVRRYEEVARGYVLA

Sequences:

>Translated_519_residues
MLQDPRSAILAAATAPGTWDVLVIGGGASGLGTAVEAATRGHRTLLLEGHDYAKGTSSRSTKLVHGGVRYLAQGNVSLVR
EALHERGLLRKNAPHLTRNLSFVVPAYDWWAGPFYGIGLKLYDILAGRLNLGSSKYLGKEAALERTPTLQAEGLMGGILY
FDGQFDDARLAVTLLRTLEDHGGVALNYAPVTGLIQENGKVVGARFRDLETGQAYAARARVVVNATGVWVDDIRRMENPD
AKPMLSPSQGSHVVVEKRFLPGDSAIMIPRTDDGRVLFAVPWHDHVVIGTTDLPVPSTPFEPRPLEEEIEFILKTAARYL
DPAPTRADVRSVYAGLRPLVKNERTDGAGSTAALSRDHVIRISDGGLVTLTGGKWTTYRRMGEDTVNRAEQVGGLSGRLT
VTPGLHLHGWSEEPRPDPLRVYGSDAERIRALPGADRLLHPELPYTEAELRWGVRFESARTVEDLLARRTRALLLHARAS
IEAAPRAAAILAEELGRDQAWAEEQVRRYEEVARGYVLA
>Mature_519_residues
MLQDPRSAILAAATAPGTWDVLVIGGGASGLGTAVEAATRGHRTLLLEGHDYAKGTSSRSTKLVHGGVRYLAQGNVSLVR
EALHERGLLRKNAPHLTRNLSFVVPAYDWWAGPFYGIGLKLYDILAGRLNLGSSKYLGKEAALERTPTLQAEGLMGGILY
FDGQFDDARLAVTLLRTLEDHGGVALNYAPVTGLIQENGKVVGARFRDLETGQAYAARARVVVNATGVWVDDIRRMENPD
AKPMLSPSQGSHVVVEKRFLPGDSAIMIPRTDDGRVLFAVPWHDHVVIGTTDLPVPSTPFEPRPLEEEIEFILKTAARYL
DPAPTRADVRSVYAGLRPLVKNERTDGAGSTAALSRDHVIRISDGGLVTLTGGKWTTYRRMGEDTVNRAEQVGGLSGRLT
VTPGLHLHGWSEEPRPDPLRVYGSDAERIRALPGADRLLHPELPYTEAELRWGVRFESARTVEDLLARRTRALLLHARAS
IEAAPRAAAILAEELGRDQAWAEEQVRRYEEVARGYVLA

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=552, Percent_Identity=40.036231884058, Blast_Score=381, Evalue=1e-105,
Organism=Homo sapiens, GI285002231, Length=552, Percent_Identity=40.036231884058, Blast_Score=381, Evalue=1e-105,
Organism=Escherichia coli, GI2367226, Length=463, Percent_Identity=31.5334773218143, Blast_Score=173, Evalue=3e-44,
Organism=Escherichia coli, GI1788574, Length=504, Percent_Identity=29.9603174603175, Blast_Score=128, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17509253, Length=549, Percent_Identity=39.5264116575592, Blast_Score=351, Evalue=5e-97,
Organism=Caenorhabditis elegans, GI115534726, Length=544, Percent_Identity=37.5, Blast_Score=334, Evalue=5e-92,
Organism=Saccharomyces cerevisiae, GI6322036, Length=577, Percent_Identity=35.7019064124783, Blast_Score=311, Evalue=1e-85,
Organism=Drosophila melanogaster, GI161077125, Length=548, Percent_Identity=38.8686131386861, Blast_Score=361, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24653942, Length=548, Percent_Identity=38.8686131386861, Blast_Score=361, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24653944, Length=548, Percent_Identity=38.8686131386861, Blast_Score=361, Evalue=1e-100,
Organism=Drosophila melanogaster, GI20130025, Length=548, Percent_Identity=38.8686131386861, Blast_Score=361, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24586295, Length=537, Percent_Identity=34.4506517690875, Blast_Score=289, Evalue=3e-78,
Organism=Drosophila melanogaster, GI19921278, Length=537, Percent_Identity=30.5400372439479, Blast_Score=240, Evalue=2e-63,
Organism=Drosophila melanogaster, GI45550977, Length=396, Percent_Identity=29.040404040404, Blast_Score=167, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 56658; Mature: 56658

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQDPRSAILAAATAPGTWDVLVIGGGASGLGTAVEAATRGHRTLLLEGHDYAKGTSSRS
CCCCCCHHEEEEECCCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCC
TKLVHGGVRYLAQGNVSLVREALHERGLLRKNAPHLTRNLSFVVPAYDWWAGPFYGIGLK
EEEEECCCHHEECCCHHHHHHHHHHCCCCCCCCCCHHCCCEEEEECHHHCCCCHHHCCHH
LYDILAGRLNLGSSKYLGKEAALERTPTLQAEGLMGGILYFDGQFDDARLAVTLLRTLED
HHHHHHHHCCCCCCHHCCCHHHHCCCCCCEECCCEEEEEEECCCCCCHHHHHHHHHHHHH
HGGVALNYAPVTGLIQENGKVVGARFRDLETGQAYAARARVVVNATGVWVDDIRRMENPD
CCCEEEEECCEEEEEECCCEEEEEEECCCCCCCHHHEEEEEEEEECCCCHHHHHHHCCCC
AKPMLSPSQGSHVVVEKRFLPGDSAIMIPRTDDGRVLFAVPWHDHVVIGTTDLPVPSTPF
CCCCCCCCCCCEEEEEEEECCCCCEEEEEECCCCEEEEEECCCCEEEEECCCCCCCCCCC
EPRPLEEEIEFILKTAARYLDPAPTRADVRSVYAGLRPLVKNERTDGAGSTAALSRDHVI
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCEE
RISDGGLVTLTGGKWTTYRRMGEDTVNRAEQVGGLSGRLTVTPGLHLHGWSEEPRPDPLR
EECCCCEEEEECCCEEEHHHHCHHHHHHHHHHCCCCCEEEECCCEEEECCCCCCCCCCEE
VYGSDAERIRALPGADRLLHPELPYTEAELRWGVRFESARTVEDLLARRTRALLLHARAS
EECCCHHHHCCCCCCCCCCCCCCCCCHHHEEECEEECCCCCHHHHHHHHHHHHHHHHHHC
IEAAPRAAAILAEELGRDQAWAEEQVRRYEEVARGYVLA
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEECC
>Mature Secondary Structure
MLQDPRSAILAAATAPGTWDVLVIGGGASGLGTAVEAATRGHRTLLLEGHDYAKGTSSRS
CCCCCCHHEEEEECCCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCC
TKLVHGGVRYLAQGNVSLVREALHERGLLRKNAPHLTRNLSFVVPAYDWWAGPFYGIGLK
EEEEECCCHHEECCCHHHHHHHHHHCCCCCCCCCCHHCCCEEEEECHHHCCCCHHHCCHH
LYDILAGRLNLGSSKYLGKEAALERTPTLQAEGLMGGILYFDGQFDDARLAVTLLRTLED
HHHHHHHHCCCCCCHHCCCHHHHCCCCCCEECCCEEEEEEECCCCCCHHHHHHHHHHHHH
HGGVALNYAPVTGLIQENGKVVGARFRDLETGQAYAARARVVVNATGVWVDDIRRMENPD
CCCEEEEECCEEEEEECCCEEEEEEECCCCCCCHHHEEEEEEEEECCCCHHHHHHHCCCC
AKPMLSPSQGSHVVVEKRFLPGDSAIMIPRTDDGRVLFAVPWHDHVVIGTTDLPVPSTPF
CCCCCCCCCCCEEEEEEEECCCCCEEEEEECCCCEEEEEECCCCEEEEECCCCCCCCCCC
EPRPLEEEIEFILKTAARYLDPAPTRADVRSVYAGLRPLVKNERTDGAGSTAALSRDHVI
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCEE
RISDGGLVTLTGGKWTTYRRMGEDTVNRAEQVGGLSGRLTVTPGLHLHGWSEEPRPDPLR
EECCCCEEEEECCCEEEHHHHCHHHHHHHHHHCCCCCEEEECCCEEEECCCCCCCCCCEE
VYGSDAERIRALPGADRLLHPELPYTEAELRWGVRFESARTVEDLLARRTRALLLHARAS
EECCCHHHHCCCCCCCCCCCCCCCCCHHHEEECEEECCCCCHHHHHHHHHHHHHHHHHHC
IEAAPRAAAILAEELGRDQAWAEEQVRRYEEVARGYVLA
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]