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The map label for this gene is aroB [H]

Identifier: 94971942

GI number: 94971942

Start: 2611

End: 3828

Strand: Direct

Name: aroB [H]

Synonym: Dgeo_2474

Alternate gene names: 94971942

Gene position: 2611-3828 (Clockwise)

Preceding gene: 94971943

Following gene: 94971941

Centisome position: 0.45

GC content: 66.09

Gene sequence:

>1218_bases
ATGCCGCTGAACCGGGTGATCGCGCAGACTGTGCCGGTCACGTTTCGTTACACCGTTCAGTTCACCCACGGCCTGTTTCA
GCTGGAGAATCCGGTGCTGCGCACCACGCTGGCCGGGGACACCCAGGACCCTGTCAAGGTGATGTGCGTCATCGACGCCG
GGGTTCTGGCAGCTTTTCCCGAGCTGCGAGACCAGATCGGCCGCTATTTCGCCCGGCACGCTGGCGCCCTGCATCTGGTC
GCGCCGCCCCTGATCGTACCAGGTGGTGAGCGCGTCAAGCAGGAAGAAGGCTGGGTGCGGCAGGTGCAGGACCAGATTCA
CTGCTGCGGGATCGACCGTCATTCCTTTGTGATGGTGGTGGGCGGCGGCGCGGTGATCGACATGGTGGGCTTTGCAGCTG
CCACGGCCCACCGAGGGGTCCGGCTGGTTCGGGTGCCCACCACCGTCCTCGCGCAGAACGACTCGGGCGTGGGCGTCAAG
AACAGCGTGAATGCCTACGGCAAGAAGAATTGGCTGGGGACCTTCGCGCCGCCCTACGCCGTGTTGAACGACTTGGGCTT
CTTGCCGGCGCTGGCGGACCGCGATTGGCTGGGCGGGCTGGCTGAGGCAGTCAAGGTCGCGCTGCTGAAAGACGCTGCCT
TCTTCGCCTGGCTTGAGGACCACGCCGGAGCGCTGGTGAACCGCGACCTGACGGCGATGGAGGACGCGGTTTACCGCTGT
GCGGAGTTGCATCTCGCGCACATTGCCGGAAGCGGTGATCCCTTTGAGATGGGTTCCTCGCGGCCCCTCGACTTCGGGCA
CTGGGCGGCGCACAAGCTTGAGAGCCTGACCGCCTACACGCTGCGCCACGGTGAGGCGGTGGCGGTAGGCTTGGCCCTCG
ACTGCACCTATGCCGTGCTCAAGGGCCTGCTCCCCGAAGCCGACTGGCGGCGCGTCCTCGACCTGCTGCTGGCGCTGCGG
CTCCCGGTCTATGTACCGGAACTGGGTACCTCGGCCCAGGACCCCGCAGACCCCATGAGCGTGTTGAGCGGCTTGAACGA
GTTCCGCGAGCACCTGGGCGGGCGCCTCACCGTCCCGCTGCTGACCGCCGTCGGCCAGATGACCGAGGTGCATGAGCTGG
ATCTCGGCCTGCTGCGCCGCAGTGTTGGCCTGCTCAAAGACCTGCACGACCACCACTCAGGAGCGATATGTCTGCCTACG
CCAATCCCTGCCTGCTAA

Upstream 100 bases:

>100_bases
GATTCGTTTATGTCGACTGCGGCAGATTGCTGGGCATGAACACCAAGCCGAGAGGCAAGGTCTGTGGCAGGGCCAGTGAA
GGCCCCTGTGCGAGGAACGT

Downstream 100 bases:

>100_bases
CCCAGACGCAACTGCTTGATCTCTCCTTTCTGGAACACCGTGCCCAGCTGCTCGCGCTGGCGGCCTTTCTGGACCGGCTG
GACCGGGCGCAAGGGGCTGA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MPLNRVIAQTVPVTFRYTVQFTHGLFQLENPVLRTTLAGDTQDPVKVMCVIDAGVLAAFPELRDQIGRYFARHAGALHLV
APPLIVPGGERVKQEEGWVRQVQDQIHCCGIDRHSFVMVVGGGAVIDMVGFAAATAHRGVRLVRVPTTVLAQNDSGVGVK
NSVNAYGKKNWLGTFAPPYAVLNDLGFLPALADRDWLGGLAEAVKVALLKDAAFFAWLEDHAGALVNRDLTAMEDAVYRC
AELHLAHIAGSGDPFEMGSSRPLDFGHWAAHKLESLTAYTLRHGEAVAVGLALDCTYAVLKGLLPEADWRRVLDLLLALR
LPVYVPELGTSAQDPADPMSVLSGLNEFREHLGGRLTVPLLTAVGQMTEVHELDLGLLRRSVGLLKDLHDHHSGAICLPT
PIPAC

Sequences:

>Translated_405_residues
MPLNRVIAQTVPVTFRYTVQFTHGLFQLENPVLRTTLAGDTQDPVKVMCVIDAGVLAAFPELRDQIGRYFARHAGALHLV
APPLIVPGGERVKQEEGWVRQVQDQIHCCGIDRHSFVMVVGGGAVIDMVGFAAATAHRGVRLVRVPTTVLAQNDSGVGVK
NSVNAYGKKNWLGTFAPPYAVLNDLGFLPALADRDWLGGLAEAVKVALLKDAAFFAWLEDHAGALVNRDLTAMEDAVYRC
AELHLAHIAGSGDPFEMGSSRPLDFGHWAAHKLESLTAYTLRHGEAVAVGLALDCTYAVLKGLLPEADWRRVLDLLLALR
LPVYVPELGTSAQDPADPMSVLSGLNEFREHLGGRLTVPLLTAVGQMTEVHELDLGLLRRSVGLLKDLHDHHSGAICLPT
PIPAC
>Mature_404_residues
PLNRVIAQTVPVTFRYTVQFTHGLFQLENPVLRTTLAGDTQDPVKVMCVIDAGVLAAFPELRDQIGRYFARHAGALHLVA
PPLIVPGGERVKQEEGWVRQVQDQIHCCGIDRHSFVMVVGGGAVIDMVGFAAATAHRGVRLVRVPTTVLAQNDSGVGVKN
SVNAYGKKNWLGTFAPPYAVLNDLGFLPALADRDWLGGLAEAVKVALLKDAAFFAWLEDHAGALVNRDLTAMEDAVYRCA
ELHLAHIAGSGDPFEMGSSRPLDFGHWAAHKLESLTAYTLRHGEAVAVGLALDCTYAVLKGLLPEADWRRVLDLLLALRL
PVYVPELGTSAQDPADPMSVLSGLNEFREHLGGRLTVPLLTAVGQMTEVHELDLGLLRRSVGLLKDLHDHHSGAICLPTP
IPAC

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=225, Percent_Identity=39.5555555555556, Blast_Score=131, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6320332, Length=312, Percent_Identity=29.1666666666667, Blast_Score=127, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 43785; Mature: 43654

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLNRVIAQTVPVTFRYTVQFTHGLFQLENPVLRTTLAGDTQDPVKVMCVIDAGVLAAFP
CCHHHHHHHHCCEEEEEEEEEHHHHHHHCCCHHEEEECCCCCCCEEEEEEECCHHHHHHH
ELRDQIGRYFARHAGALHLVAPPLIVPGGERVKQEEGWVRQVQDQIHCCGIDRHSFVMVV
HHHHHHHHHHHHHCCEEEEECCCEECCCCHHHHHHHHHHHHHHHHHHEECCCCCCEEEEE
GGGAVIDMVGFAAATAHRGVRLVRVPTTVLAQNDSGVGVKNSVNAYGKKNWLGTFAPPYA
CCCHHHHHHHHHHHHHHCCEEEEEECCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHH
VLNDLGFLPALADRDWLGGLAEAVKVALLKDAAFFAWLEDHAGALVNRDLTAMEDAVYRC
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHH
AELHLAHIAGSGDPFEMGSSRPLDFGHWAAHKLESLTAYTLRHGEAVAVGLALDCTYAVL
HHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEECCCEEEEEEHHHHHHHHH
KGLLPEADWRRVLDLLLALRLPVYVPELGTSAQDPADPMSVLSGLNEFREHLGGRLTVPL
HHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEHHH
LTAVGQMTEVHELDLGLLRRSVGLLKDLHDHHSGAICLPTPIPAC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
>Mature Secondary Structure 
PLNRVIAQTVPVTFRYTVQFTHGLFQLENPVLRTTLAGDTQDPVKVMCVIDAGVLAAFP
CHHHHHHHHCCEEEEEEEEEHHHHHHHCCCHHEEEECCCCCCCEEEEEEECCHHHHHHH
ELRDQIGRYFARHAGALHLVAPPLIVPGGERVKQEEGWVRQVQDQIHCCGIDRHSFVMVV
HHHHHHHHHHHHHCCEEEEECCCEECCCCHHHHHHHHHHHHHHHHHHEECCCCCCEEEEE
GGGAVIDMVGFAAATAHRGVRLVRVPTTVLAQNDSGVGVKNSVNAYGKKNWLGTFAPPYA
CCCHHHHHHHHHHHHHHCCEEEEEECCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHH
VLNDLGFLPALADRDWLGGLAEAVKVALLKDAAFFAWLEDHAGALVNRDLTAMEDAVYRC
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHH
AELHLAHIAGSGDPFEMGSSRPLDFGHWAAHKLESLTAYTLRHGEAVAVGLALDCTYAVL
HHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEECCCEEEEEEHHHHHHHHH
KGLLPEADWRRVLDLLLALRLPVYVPELGTSAQDPADPMSVLSGLNEFREHLGGRLTVPL
HHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEHHH
LTAVGQMTEVHELDLGLLRRSVGLLKDLHDHHSGAICLPTPIPAC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA