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The map label for this gene is hyuA [H]

Identifier: 94971910

GI number: 94971910

Start: 41764

End: 43848

Strand: Direct

Name: hyuA [H]

Synonym: Dgeo_2442

Alternate gene names: 94971910

Gene position: 41764-43848 (Clockwise)

Preceding gene: 94971911

Following gene: 94971904

Centisome position: 7.27

GC content: 67.19

Gene sequence:

>2085_bases
TTGACCGCGGCTACAGATCCCCCGGGGTCCATTCCGGTGCGGATTGGCATCGATGTGGGCGGCACCTTTACCAAGGGTGT
CGCTCTCGATCCCGAGGGGCGCATGCTTGCGGTGTCCCACGTGCCCACCACGCACGGCCACGAACATGGCGTTGCCAACG
GTGTCCTCCAAGCCCTGCGGGCGCTGCTGCGTGACTTGCCGCCCACAGCTGTTCCGGTGCTGATTGCTCACTCCACCACG
CAGGCCACCAATGCCCTGCTGGAGGGGGACACGGCCTTGGTCGGGATCCTTGCCCTGGGCGAAGTGCGCGACGAGCGGCG
TATCAGGAAGGTCACGCGACCCCCGATGGGCCTGCGTGCGCTCCAGGCGTTTGTGGCGACCGATCGGCCTGGTTTCGAGG
AGCGGGTTCAGACCGTGCTGAAAGACTGGAGGAGCCGGAAGGTCGGGGCGGTGGCCGTCTCGCAGGCATTCGGTGTGGAC
GACCCTCGCTTTGAGCGGCGCGCGGGGGAACTGGCAAGGGAGGCGGGCTTACCCGTCAGCCTCGGCAGTGATCTATCGGG
CGCCTACGGATTGGAGATGCGCACCCTGTCCGCCACCGTGAATGCCAGCATCCTCCCGACGATGGTGCGCACGGCCGAGC
ACGTCCGGAGAGCGGTGGGTGAGCTTCTGCCAGACGTACCGCTCCTGATCGTCCGCGGAGACGGCGGCGCGGCCGATCTG
CGCGCCTTTGAGGAAATGCCGCTGCATACCGTGGTGAGTGGTCCTGCCGCGAGTCTGAGTGGAGCGATTCTCACGCACGG
CGTGATGGACGGCGTGTTCTTTGAGGTGGGCGGCACGAGTACGAACATTGGCGTGATCAAAGACGGGCGGCCCGCCCTGA
AGTACATGACGGTGATGGACGTACCGACTGGGCTACGTGCCGCGGACATCCGCATTGCTGGCGTTGCGGGTGGCAGCTTG
GTGCGGTTGCGTGGGCGCCGGATCGAGGATGTTGGCCCAAGAAGTGCTCACATTGCAGGGTTGCCGTATGCGAGCTTCGT
GTCACCAGACCGTCTGGCGCATGCACGGGTTGAGCGCCTCGCTCCCCGTCCTGGCGACCCGGCAGACTATGCGGTGCTTC
AGACGCCCGACGGGTCGCGGTTCGCGATCACCCCGACGTGCGCCGCGAACGCTCTGGGCGCCATTCCCGAGGGTGCCTCT
GCCTATGCCGTTCCCGAGAGTGCTCGGCTCGCGCTCGGTCTACTGGGGCAGGCCCTCGGCGCCGGGATGGAAGCGGCCGC
CCACGCCGTGCTGGAAGCCAGCGCGGAGAAGCTGATGGGCACTGTACAGGCGCTCGTGCGCGAGTACGGGCTGCGCGGCA
CGCCTCTGTATGGCGGCGGCGGCGCGGCCAGCGTGCTTGGTCCAGTCGTCGCCCGCCGCTTGAATGCTCCCTTCATCCCA
ATTCCGCACAGCGACGTGATTTCGTCTATTGGGGCAGCTCTCGCCGTCATTCGGGTGGAACGAGAGCGCAGCGTGACCCG
CCAGGATCCCGCCGTTGCGGATCTCCTCGAGCGCGAGGTGGGCGAGGAGGCCGTGCGGCTGGGCGCTGACCCCGCCTCAC
TGCGCATCGACCTAGAGTACAGGGCCCGTGAAGGCCGCCTGCTGGCCGTCGCGATCGGTGCCCATCCGCTGAGCACCCAT
ACCCGCCTGCTTGACGCAGACGAGTTGTGGCAGCAGGCCCGGCAGGTGCTGGGAGGCCAGGCCCAACCGGTGTTCGGCAG
TCCCCATCACATGTTGTTTGTCGCTGCCCGTAGCCGGCGCGGCCTGTTGCGGCGAGGCGAACAGCACGCCGCCCTCGTTC
TTGATCGGCGCGGGGTACGGCTGCTGCGCTTCGAGAACGCACAGGTCCTCACCGGTCATCCGCACGAGGTGCTGGAACGG
TTGTGCGCACGGCTTGCAAAACGCGCTATCGCGCCGCATGTCGTCGCCCTGACCACCTCCCGGGTGCGGGATTACGCCCA
CCTGCACGACCCGGCCCTGCTGTTGCAGCAACTTGCTGAGAACCTGCAACTGGAGGACCAGGTCGCGCTCATTGTCGAGC
CGTGA

Upstream 100 bases:

>100_bases
CTGATGGTTCTGGTGTACGTCGTGGGTGTTATTGTGTTCCGCCTGCGCACACAGCGCCGGGCGGAGCGCGGAGCACACAC
GTGATGGCGGAGGCTCAGCG

Downstream 100 bases:

>100_bases
GTTTTGGGGCCGGAGCTGCTCTCAACACGCGCACTGCGGGCCAGGAGCAGAACATTTGCCAAAGGCGCTGGGGTTAGGGC
ACGCGAACCTGGAAACACAC

Product: hydantoinase/oxoprolinase

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 694; Mature: 693

Protein sequence:

>694_residues
MTAATDPPGSIPVRIGIDVGGTFTKGVALDPEGRMLAVSHVPTTHGHEHGVANGVLQALRALLRDLPPTAVPVLIAHSTT
QATNALLEGDTALVGILALGEVRDERRIRKVTRPPMGLRALQAFVATDRPGFEERVQTVLKDWRSRKVGAVAVSQAFGVD
DPRFERRAGELAREAGLPVSLGSDLSGAYGLEMRTLSATVNASILPTMVRTAEHVRRAVGELLPDVPLLIVRGDGGAADL
RAFEEMPLHTVVSGPAASLSGAILTHGVMDGVFFEVGGTSTNIGVIKDGRPALKYMTVMDVPTGLRAADIRIAGVAGGSL
VRLRGRRIEDVGPRSAHIAGLPYASFVSPDRLAHARVERLAPRPGDPADYAVLQTPDGSRFAITPTCAANALGAIPEGAS
AYAVPESARLALGLLGQALGAGMEAAAHAVLEASAEKLMGTVQALVREYGLRGTPLYGGGGAASVLGPVVARRLNAPFIP
IPHSDVISSIGAALAVIRVERERSVTRQDPAVADLLEREVGEEAVRLGADPASLRIDLEYRAREGRLLAVAIGAHPLSTH
TRLLDADELWQQARQVLGGQAQPVFGSPHHMLFVAARSRRGLLRRGEQHAALVLDRRGVRLLRFENAQVLTGHPHEVLER
LCARLAKRAIAPHVVALTTSRVRDYAHLHDPALLLQQLAENLQLEDQVALIVEP

Sequences:

>Translated_694_residues
MTAATDPPGSIPVRIGIDVGGTFTKGVALDPEGRMLAVSHVPTTHGHEHGVANGVLQALRALLRDLPPTAVPVLIAHSTT
QATNALLEGDTALVGILALGEVRDERRIRKVTRPPMGLRALQAFVATDRPGFEERVQTVLKDWRSRKVGAVAVSQAFGVD
DPRFERRAGELAREAGLPVSLGSDLSGAYGLEMRTLSATVNASILPTMVRTAEHVRRAVGELLPDVPLLIVRGDGGAADL
RAFEEMPLHTVVSGPAASLSGAILTHGVMDGVFFEVGGTSTNIGVIKDGRPALKYMTVMDVPTGLRAADIRIAGVAGGSL
VRLRGRRIEDVGPRSAHIAGLPYASFVSPDRLAHARVERLAPRPGDPADYAVLQTPDGSRFAITPTCAANALGAIPEGAS
AYAVPESARLALGLLGQALGAGMEAAAHAVLEASAEKLMGTVQALVREYGLRGTPLYGGGGAASVLGPVVARRLNAPFIP
IPHSDVISSIGAALAVIRVERERSVTRQDPAVADLLEREVGEEAVRLGADPASLRIDLEYRAREGRLLAVAIGAHPLSTH
TRLLDADELWQQARQVLGGQAQPVFGSPHHMLFVAARSRRGLLRRGEQHAALVLDRRGVRLLRFENAQVLTGHPHEVLER
LCARLAKRAIAPHVVALTTSRVRDYAHLHDPALLLQQLAENLQLEDQVALIVEP
>Mature_693_residues
TAATDPPGSIPVRIGIDVGGTFTKGVALDPEGRMLAVSHVPTTHGHEHGVANGVLQALRALLRDLPPTAVPVLIAHSTTQ
ATNALLEGDTALVGILALGEVRDERRIRKVTRPPMGLRALQAFVATDRPGFEERVQTVLKDWRSRKVGAVAVSQAFGVDD
PRFERRAGELAREAGLPVSLGSDLSGAYGLEMRTLSATVNASILPTMVRTAEHVRRAVGELLPDVPLLIVRGDGGAADLR
AFEEMPLHTVVSGPAASLSGAILTHGVMDGVFFEVGGTSTNIGVIKDGRPALKYMTVMDVPTGLRAADIRIAGVAGGSLV
RLRGRRIEDVGPRSAHIAGLPYASFVSPDRLAHARVERLAPRPGDPADYAVLQTPDGSRFAITPTCAANALGAIPEGASA
YAVPESARLALGLLGQALGAGMEAAAHAVLEASAEKLMGTVQALVREYGLRGTPLYGGGGAASVLGPVVARRLNAPFIPI
PHSDVISSIGAALAVIRVERERSVTRQDPAVADLLEREVGEEAVRLGADPASLRIDLEYRAREGRLLAVAIGAHPLSTHT
RLLDADELWQQARQVLGGQAQPVFGSPHHMLFVAARSRRGLLRRGEQHAALVLDRRGVRLLRFENAQVLTGHPHEVLERL
CARLAKRAIAPHVVALTTSRVRDYAHLHDPALLLQQLAENLQLEDQVALIVEP

Specific function: HyuA and hyuB convert D- and L-substituted hydantoins to corresponding N-carbamyl-amino acids [H]

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: NA

Molecular weight: Translated: 73564; Mature: 73432

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAATDPPGSIPVRIGIDVGGTFTKGVALDPEGRMLAVSHVPTTHGHEHGVANGVLQALR
CCCCCCCCCCCEEEEEEECCCCCCCCEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
ALLRDLPPTAVPVLIAHSTTQATNALLEGDTALVGILALGEVRDERRIRKVTRPPMGLRA
HHHHHCCCCCEEEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
LQAFVATDRPGFEERVQTVLKDWRSRKVGAVAVSQAFGVDDPRFERRAGELAREAGLPVS
HHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEHHHCCCCCHHHHHHHHHHHHHCCCCEE
LGSDLSGAYGLEMRTLSATVNASILPTMVRTAEHVRRAVGELLPDVPLLIVRGDGGAADL
CCCCCCCCCCCEEEEEEHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHH
RAFEEMPLHTVVSGPAASLSGAILTHGVMDGVFFEVGGTSTNIGVIKDGRPALKYMTVMD
HHHHHCCCHHEECCCHHHHCCHHHHHHHHHCEEEEECCCCCCEEEEECCCCHHEEEEEEE
VPTGLRAADIRIAGVAGGSLVRLRGRRIEDVGPRSAHIAGLPYASFVSPDRLAHARVERL
CCCCCEEEEEEEEEECCCCEEEECCCCCCCCCCCCCEEECCCCHHHCCHHHHHHHHHHHH
APRPGDPADYAVLQTPDGSRFAITPTCAANALGAIPEGASAYAVPESARLALGLLGQALG
CCCCCCCCCEEEEECCCCCEEEECCCHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHC
AGMEAAAHAVLEASAEKLMGTVQALVREYGLRGTPLYGGGGAASVLGPVVARRLNAPFIP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
IPHSDVISSIGAALAVIRVERERSVTRQDPAVADLLEREVGEEAVRLGADPASLRIDLEY
CCCHHHHHHHHHHHHHHEEHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEE
RAREGRLLAVAIGAHPLSTHTRLLDADELWQQARQVLGGQAQPVFGSPHHMLFVAARSRR
ECCCCCEEEEEECCCCCCCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECHHH
GLLRRGEQHAALVLDRRGVRLLRFENAQVLTGHPHEVLERLCARLAKRAIAPHVVALTTS
HHHHCCCCCEEEEEECCCEEEEEECCCEEEECCHHHHHHHHHHHHHHHHCCCEEEEEEHH
RVRDYAHLHDPALLLQQLAENLQLEDQVALIVEP
HHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEECC
>Mature Secondary Structure 
TAATDPPGSIPVRIGIDVGGTFTKGVALDPEGRMLAVSHVPTTHGHEHGVANGVLQALR
CCCCCCCCCCEEEEEEECCCCCCCCEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
ALLRDLPPTAVPVLIAHSTTQATNALLEGDTALVGILALGEVRDERRIRKVTRPPMGLRA
HHHHHCCCCCEEEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
LQAFVATDRPGFEERVQTVLKDWRSRKVGAVAVSQAFGVDDPRFERRAGELAREAGLPVS
HHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEHHHCCCCCHHHHHHHHHHHHHCCCCEE
LGSDLSGAYGLEMRTLSATVNASILPTMVRTAEHVRRAVGELLPDVPLLIVRGDGGAADL
CCCCCCCCCCCEEEEEEHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHH
RAFEEMPLHTVVSGPAASLSGAILTHGVMDGVFFEVGGTSTNIGVIKDGRPALKYMTVMD
HHHHHCCCHHEECCCHHHHCCHHHHHHHHHCEEEEECCCCCCEEEEECCCCHHEEEEEEE
VPTGLRAADIRIAGVAGGSLVRLRGRRIEDVGPRSAHIAGLPYASFVSPDRLAHARVERL
CCCCCEEEEEEEEEECCCCEEEECCCCCCCCCCCCCEEECCCCHHHCCHHHHHHHHHHHH
APRPGDPADYAVLQTPDGSRFAITPTCAANALGAIPEGASAYAVPESARLALGLLGQALG
CCCCCCCCCEEEEECCCCCEEEECCCHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHC
AGMEAAAHAVLEASAEKLMGTVQALVREYGLRGTPLYGGGGAASVLGPVVARRLNAPFIP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
IPHSDVISSIGAALAVIRVERERSVTRQDPAVADLLEREVGEEAVRLGADPASLRIDLEY
CCCHHHHHHHHHHHHHHEEHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEE
RAREGRLLAVAIGAHPLSTHTRLLDADELWQQARQVLGGQAQPVFGSPHHMLFVAARSRR
ECCCCCEEEEEECCCCCCCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECHHH
GLLRRGEQHAALVLDRRGVRLLRFENAQVLTGHPHEVLERLCARLAKRAIAPHVVALTTS
HHHHCCCCCEEEEEECCCEEEEEECCCEEEECCHHHHHHHHHHHHHHHHCCCEEEEEEHH
RVRDYAHLHDPALLLQQLAENLQLEDQVALIVEP
HHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1732229 [H]