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The map label for this gene is tcp [H]

Identifier: 94314854

GI number: 94314854

Start: 138284

End: 139846

Strand: Direct

Name: tcp [H]

Synonym: Rmet_5935

Alternate gene names: 94314854

Gene position: 138284-139846 (Clockwise)

Preceding gene: 94314852

Following gene: 291481478

Centisome position: 5.36

GC content: 66.35

Gene sequence:

>1563_bases
ATGAATCGACTTACCCTCAATACCAAACTCTGGGCGGCGCTTGCCGTCATGTGGTTGCTGCTGCTTGCGCTCGGTACATG
GAATGCCTTCCACGCGCGGTCCGTGATGATGGCCGAGCGGCGCGACGCGCTGCAATCGCTTGTGACCACCGGCGAGGGCA
TCGTCAAGCTGTACGCTGAACGCGCCGCCAAGGGCGTGATGTCGAAAGAGGACGCCCAGGCCGCCGCCAAGGACGCGCTG
CGCGCGATGCGCTTCGGCCAGAACGGCTACCTGTTCATTGTCGATTCCAAGCCGCAGGTGGTGCTGAACCCGGGCCTGCC
GCAGACCGAAGGCAATATGGTCGGCGACTTCAAGGACCCCGACGGGGTGTACGTCTACCGCGCGATTATCGAAGGCGCGC
GCCGCACCACCGGCGAGGACGCTGGCTTTTCGACCTACCGGGGCCGCCTGCCCGGCACCGAAACGCCGAAGCGCAAGCTG
ACCTACGGGCGCTACGTGGCGGACTGGGACTGGTTCGTCGCCACGGGCGTGTTCCTGGTCGACATCGAGGATGCCTTCCG
CGCCAACCTGATCAACGCGATCGCCAGTACCTTGCTGATCGGAGCGCTGATTGCGGCCGTGATGGGCATGATCATGCGGA
CGGTCCAGCGCAGTCTTGGTGGCGAGCCGGCCTACGCCGTGGAATCAGTGACGCGTATCGCGGGCGGCGACCTGACCGTG
CCGCTGCAGGTGCGCGGTGACGACGATCGCAGCGTGCTGGCCGCCATGCAGCAGATGCAGGAGCGACTTGCCGCAACGCT
GGGCGATATCCGCGGCGCGGCCGGCGCCATCGCCAGCGCCACGCATCAGATCTCGGCTGGCAACAACGATCTCTCGCAAC
GGACTGAACAGCAGGCCGCCGCGCTCGAGCAGACCGCATCGAGCATGGAGGAACTGACCGGCATCGTGCGCCAGAACGCC
GACAATGCGCGGCAGGCCAGCGCGCTGGCCGTCAACGCGTCGGAGATCGCCAACCGTGGCGGCGAGGTGGTCAGCGAAGT
GGTGAGCACGATGGGCGAGATCAACCAGGCCTCGCGCAAGATCGTCGACATCATCGGCGTGATCGAGGGCATCGCATTCC
AGACCAATATCCTGGCGCTGAACGCTGCGGTGGAAGCCGCGCGCGCCGGTGAACAAGGACGCGGGTTCGCGGTGGTGGCG
GGTGAGGTGCGTAGTCTCGCCCAACGCAGCGCCAATGCGGCGAAGGAGATCAAGACGCTGATCGACAACTCGGTGGCGCA
GGTCGACACCGGTTCGACACTGGTGGCCAAGGCCGGCGCCACAATGCAGGAGGTGGTTGGCGCGGTCAGACGCGTCACCG
ACATCATGGGCGAGATCAGCGCCGCGTCGGCCGAGCAGAGCACCGGCATCGAGCAGGTGGGCCAGGCCGTGACGCAGATG
GACTCCGTCACGCAGCAGAATGCCGCGCTTGTGGAAGAAGCGGCCGCTGCCGCGCAATCGCTGGCCGAGCAGGCGCAGTC
GATGATGCGTGCGGTGTCGGCGTTCCGGCTGGCAACGGTCTGA

Upstream 100 bases:

>100_bases
GCGTGGCGCCAGTGGCGTGACCCCCGACCAGGGGCGGACTAAGGGTTTTGCCGCGGTGTGCCGATATTCACGAGGTCTCA
GGTAACCCCCCTGCCGGATC

Downstream 100 bases:

>100_bases
ACCTGCTGGCCTTCCTGTTATCGACGACTTCCCGTCATCACGCCGTCTGCGATGATGCGGGCTGTAGCGCGCGCATGGCA
TCGGCTGCGATCTCGAACGA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 520; Mature: 520

Protein sequence:

>520_residues
MNRLTLNTKLWAALAVMWLLLLALGTWNAFHARSVMMAERRDALQSLVTTGEGIVKLYAERAAKGVMSKEDAQAAAKDAL
RAMRFGQNGYLFIVDSKPQVVLNPGLPQTEGNMVGDFKDPDGVYVYRAIIEGARRTTGEDAGFSTYRGRLPGTETPKRKL
TYGRYVADWDWFVATGVFLVDIEDAFRANLINAIASTLLIGALIAAVMGMIMRTVQRSLGGEPAYAVESVTRIAGGDLTV
PLQVRGDDDRSVLAAMQQMQERLAATLGDIRGAAGAIASATHQISAGNNDLSQRTEQQAAALEQTASSMEELTGIVRQNA
DNARQASALAVNASEIANRGGEVVSEVVSTMGEINQASRKIVDIIGVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVA
GEVRSLAQRSANAAKEIKTLIDNSVAQVDTGSTLVAKAGATMQEVVGAVRRVTDIMGEISAASAEQSTGIEQVGQAVTQM
DSVTQQNAALVEEAAAAAQSLAEQAQSMMRAVSAFRLATV

Sequences:

>Translated_520_residues
MNRLTLNTKLWAALAVMWLLLLALGTWNAFHARSVMMAERRDALQSLVTTGEGIVKLYAERAAKGVMSKEDAQAAAKDAL
RAMRFGQNGYLFIVDSKPQVVLNPGLPQTEGNMVGDFKDPDGVYVYRAIIEGARRTTGEDAGFSTYRGRLPGTETPKRKL
TYGRYVADWDWFVATGVFLVDIEDAFRANLINAIASTLLIGALIAAVMGMIMRTVQRSLGGEPAYAVESVTRIAGGDLTV
PLQVRGDDDRSVLAAMQQMQERLAATLGDIRGAAGAIASATHQISAGNNDLSQRTEQQAAALEQTASSMEELTGIVRQNA
DNARQASALAVNASEIANRGGEVVSEVVSTMGEINQASRKIVDIIGVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVA
GEVRSLAQRSANAAKEIKTLIDNSVAQVDTGSTLVAKAGATMQEVVGAVRRVTDIMGEISAASAEQSTGIEQVGQAVTQM
DSVTQQNAALVEEAAAAAQSLAEQAQSMMRAVSAFRLATV
>Mature_520_residues
MNRLTLNTKLWAALAVMWLLLLALGTWNAFHARSVMMAERRDALQSLVTTGEGIVKLYAERAAKGVMSKEDAQAAAKDAL
RAMRFGQNGYLFIVDSKPQVVLNPGLPQTEGNMVGDFKDPDGVYVYRAIIEGARRTTGEDAGFSTYRGRLPGTETPKRKL
TYGRYVADWDWFVATGVFLVDIEDAFRANLINAIASTLLIGALIAAVMGMIMRTVQRSLGGEPAYAVESVTRIAGGDLTV
PLQVRGDDDRSVLAAMQQMQERLAATLGDIRGAAGAIASATHQISAGNNDLSQRTEQQAAALEQTASSMEELTGIVRQNA
DNARQASALAVNASEIANRGGEVVSEVVSTMGEINQASRKIVDIIGVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVA
GEVRSLAQRSANAAKEIKTLIDNSVAQVDTGSTLVAKAGATMQEVVGAVRRVTDIMGEISAASAEQSTGIEQVGQAVTQM
DSVTQQNAALVEEAAAAAQSLAEQAQSMMRAVSAFRLATV

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=323, Percent_Identity=61.3003095975232, Blast_Score=330, Evalue=2e-91,
Organism=Escherichia coli, GI1788195, Length=305, Percent_Identity=61.6393442622951, Blast_Score=316, Evalue=3e-87,
Organism=Escherichia coli, GI1787690, Length=323, Percent_Identity=57.8947368421053, Blast_Score=310, Evalue=2e-85,
Organism=Escherichia coli, GI1788194, Length=286, Percent_Identity=60.8391608391608, Blast_Score=304, Evalue=1e-83,
Organism=Escherichia coli, GI1789453, Length=272, Percent_Identity=40.0735294117647, Blast_Score=195, Evalue=7e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 55008; Mature: 55008

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRLTLNTKLWAALAVMWLLLLALGTWNAFHARSVMMAERRDALQSLVTTGEGIVKLYAE
CCCEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
RAAKGVMSKEDAQAAAKDALRAMRFGQNGYLFIVDSKPQVVLNPGLPQTEGNMVGDFKDP
HHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCCCCCCCCCCCCCCCC
DGVYVYRAIIEGARRTTGEDAGFSTYRGRLPGTETPKRKLTYGRYVADWDWFVATGVFLV
CCHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCHHCCCCCEECCCHHHHHCCEEEE
DIEDAFRANLINAIASTLLIGALIAAVMGMIMRTVQRSLGGEPAYAVESVTRIAGGDLTV
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEE
PLQVRGDDDRSVLAAMQQMQERLAATLGDIRGAAGAIASATHQISAGNNDLSQRTEQQAA
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
ALEQTASSMEELTGIVRQNADNARQASALAVNASEIANRGGEVVSEVVSTMGEINQASRK
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHEECHHHHHHCCHHHHHHHHHHHHHHHHHHHH
IVDIIGVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRSLAQRSANAAKEIKTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
IDNSVAQVDTGSTLVAKAGATMQEVVGAVRRVTDIMGEISAASAEQSTGIEQVGQAVTQM
HCCHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHH
DSVTQQNAALVEEAAAAAQSLAEQAQSMMRAVSAFRLATV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNRLTLNTKLWAALAVMWLLLLALGTWNAFHARSVMMAERRDALQSLVTTGEGIVKLYAE
CCCEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
RAAKGVMSKEDAQAAAKDALRAMRFGQNGYLFIVDSKPQVVLNPGLPQTEGNMVGDFKDP
HHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCCCCCCCCCCCCCCCC
DGVYVYRAIIEGARRTTGEDAGFSTYRGRLPGTETPKRKLTYGRYVADWDWFVATGVFLV
CCHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCHHCCCCCEECCCHHHHHCCEEEE
DIEDAFRANLINAIASTLLIGALIAAVMGMIMRTVQRSLGGEPAYAVESVTRIAGGDLTV
ECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEE
PLQVRGDDDRSVLAAMQQMQERLAATLGDIRGAAGAIASATHQISAGNNDLSQRTEQQAA
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
ALEQTASSMEELTGIVRQNADNARQASALAVNASEIANRGGEVVSEVVSTMGEINQASRK
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHEECHHHHHHCCHHHHHHHHHHHHHHHHHHHH
IVDIIGVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRSLAQRSANAAKEIKTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
IDNSVAQVDTGSTLVAKAGATMQEVVGAVRRVTDIMGEISAASAEQSTGIEQVGQAVTQM
HCCHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHH
DSVTQQNAALVEEAAAAAQSLAEQAQSMMRAVSAFRLATV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]