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The map label for this gene is rhtC [H]

Identifier: 94314834

GI number: 94314834

Start: 116538

End: 117152

Strand: Reverse

Name: rhtC [H]

Synonym: Rmet_5915

Alternate gene names: 94314834

Gene position: 117152-116538 (Counterclockwise)

Preceding gene: 94314837

Following gene: 94314830

Centisome position: 4.54

GC content: 62.93

Gene sequence:

>615_bases
ATGACCCCACTCGCCGAACTGCTGGCCGTCGCGGCCATCACCCTTCTTGCCGTCATCAGCCCTGGCCCGGACTTCGCCAT
GGTCACGCGCAACAGCTACCTGTTTGGCCGCCGCACCGGGCTGCTTTGCGCGCTGGGCATCGCGCTCGGCGTGCAGGTAC
ACGTCGCCTACACCATGTTCGGCGTGTCACTGCTGGTGCGCCACGCGCACGGGCTGCTCTCGATCATCAAGCTGGCTGGT
GCGGCCTACTTGATCTGGATCGGCATTCAGACACTACGCAATCGCAAGGCGTTGGACGTCGACGCCGATGGGGCACCCGC
CGTTTCGGGACTGGTGGCGTTTCGCATGGGTTTCCTGACCAATGCGCTCAACCCGAAGACCACACTGTTCGTGGTCAGCA
CGTACTCGCAGGTCGTCAACGCGCACACGCCCGCCGCCGTGCAGTTTGGCTATGGATTGTTCATGTCGGCCACGCATTGG
GTCTGGTTTAGCATCGTCGCGTGGTGTTTCGGCTCGAAGTCGCTGCGTGCCACGATGCTGCGATACCAACGACAGCTCGA
TGTCATCATCGGGACTGCCCTATTCGGGCTGGGCGTGGCACTTGGCGTCAGGTAG

Upstream 100 bases:

>100_bases
TATATTGTTTGCCGTACCCGTTTCTGCGAATAAAAATGGCATATGTCGTGCCATCGAATACACGGCTTACGCAACGAAAA
CTGACTGAAATACCACAACA

Downstream 100 bases:

>100_bases
CCCACCGCATTGAGCAAGCCATCCAGATACTGCATGCAACATGCGTTACAGCCGTTACATGGCAGATCTGAAGCCAACAC
TCAGAGCGGCTGTCCGGGCG

Product: transporter, LysE-family

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MTPLAELLAVAAITLLAVISPGPDFAMVTRNSYLFGRRTGLLCALGIALGVQVHVAYTMFGVSLLVRHAHGLLSIIKLAG
AAYLIWIGIQTLRNRKALDVDADGAPAVSGLVAFRMGFLTNALNPKTTLFVVSTYSQVVNAHTPAAVQFGYGLFMSATHW
VWFSIVAWCFGSKSLRATMLRYQRQLDVIIGTALFGLGVALGVR

Sequences:

>Translated_204_residues
MTPLAELLAVAAITLLAVISPGPDFAMVTRNSYLFGRRTGLLCALGIALGVQVHVAYTMFGVSLLVRHAHGLLSIIKLAG
AAYLIWIGIQTLRNRKALDVDADGAPAVSGLVAFRMGFLTNALNPKTTLFVVSTYSQVVNAHTPAAVQFGYGLFMSATHW
VWFSIVAWCFGSKSLRATMLRYQRQLDVIIGTALFGLGVALGVR
>Mature_203_residues
TPLAELLAVAAITLLAVISPGPDFAMVTRNSYLFGRRTGLLCALGIALGVQVHVAYTMFGVSLLVRHAHGLLSIIKLAGA
AYLIWIGIQTLRNRKALDVDADGAPAVSGLVAFRMGFLTNALNPKTTLFVVSTYSQVVNAHTPAAVQFGYGLFMSATHWV
WFSIVAWCFGSKSLRATMLRYQRQLDVIIGTALFGLGVALGVR

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=200, Percent_Identity=30.5, Blast_Score=89, Evalue=1e-19,
Organism=Escherichia coli, GI1786522, Length=194, Percent_Identity=28.3505154639175, Blast_Score=88, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 21882; Mature: 21751

Theoretical pI: Translated: 10.56; Mature: 10.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPLAELLAVAAITLLAVISPGPDFAMVTRNSYLFGRRTGLLCALGIALGVQVHVAYTMF
CCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEECHHHHHHHHHHHHHHHHHHHHHHH
GVSLLVRHAHGLLSIIKLAGAAYLIWIGIQTLRNRKALDVDADGAPAVSGLVAFRMGFLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
NALNPKTTLFVVSTYSQVVNAHTPAAVQFGYGLFMSATHWVWFSIVAWCFGSKSLRATML
CCCCCCEEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RYQRQLDVIIGTALFGLGVALGVR
HHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TPLAELLAVAAITLLAVISPGPDFAMVTRNSYLFGRRTGLLCALGIALGVQVHVAYTMF
CHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEECHHHHHHHHHHHHHHHHHHHHHHH
GVSLLVRHAHGLLSIIKLAGAAYLIWIGIQTLRNRKALDVDADGAPAVSGLVAFRMGFLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
NALNPKTTLFVVSTYSQVVNAHTPAAVQFGYGLFMSATHWVWFSIVAWCFGSKSLRATML
CCCCCCEEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RYQRQLDVIIGTALFGLGVALGVR
HHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]