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The map label for this gene is qseC [H]

Identifier: 94314716

GI number: 94314716

Start: 2554898

End: 2556229

Strand: Reverse

Name: qseC [H]

Synonym: Rmet_5797

Alternate gene names: 94314716

Gene position: 2556229-2554898 (Counterclockwise)

Preceding gene: 94314717

Following gene: 94314714

Centisome position: 99.08

GC content: 68.09

Gene sequence:

>1332_bases
ATGCGCTCGATTCAACGTACGCTGCTCTGGTGGCTGGCGGCGGGGCTTGCCGTGGGGATCGCCGTGGCCACCGCGCTGAT
CTATGGGCAGGCGCGGCAGGAAGCCAACGCGCTGTTCGACTACCAGATGAAGCAACTGGCGGCCGCGTTGCCGAGCCAGT
TTTCCGCGCCGGCGCCGCCGCCGTTCGATTCCGGCAGCGCCACCGGCGCCGACCTGCTGCATGCCGACGAGGACGTCGTG
ATCCATATCTGGGATGGATCGGGACGCAGCCTCTATCTGTCGCACTCGCATCCGGCGTTGCCCCCGCAGGCGGAGCTGGG
TTTCTCGAATGCGCAGACCAACTCTGGCGAGTGGCGCATCTACAGCGTGCAGCTCGGGCCGGCGGTCGTGCAGATCGCCC
AGCCGATGAGCGCGCGTCGCACGCTGGCCGCGCATATGGCGCTGCGCACGGTGGCGCCGCTGCTGCTGTTGTTGCCGCTG
CTTGGCTGGCTGGTGTGGCTGGCGGTGGGGCGTGGCCTGCGGCCGCTGCGCGAGATTGCCAGCGAGGTGAGCGCGCGCGA
TGCCAACACGCTGGCGCCGCTGTCCGTGCGCAATATGCCCGTGGAGATCGCGCCGTTATCCGATGCCTTGAATCAGTTGC
TGGGGCGGCTGGCGCATGCCATCGACACGCAACGCGCGTTCGTGGCCGATGCCGCTCATGCGTTGCGCACGCCGCTGGCC
GCGCTGCAGTTGCAGGCTCAACTCGTCGAACGCGCCGAAAATGCCGAGGCCCGGCAGGAGGCCGTGGGCCAGCTACGGCA
GGGGCTTGAGCGGTTGACCCACCTCGTGGCGCAGTTGCTCACGCTGGCGCGGCAGGAGCCAGGTGCCGTGCCGCCGCCAC
ATGAACCGATCGACCTGCGCGAACTGGCCGTCGGCGTGGTGGCGGATATGTCCCAGGCCGCCATCAATCGCGATATCGAC
CTCGGTCTGGATGACAAGGCCGGGAGTCAGGCCACCGTGCGTGGCGATGCCGATGCCTTGCGCATCCTGCTGACCAATCT
GGTCGACAACGCGCTGCAATACATTCCGCGTGGCGGTTGCATCGATGTGCGGGTGAGCGAGATCGCGGCGGGTGTGGAAC
TGGCCGTGATCGACAACGGCCCGGGCATCTCAGCCGCCGAGCGCGAGCGCGTATTCGATCGCTTCTATCGCGTTCCAGAT
GCGCCCACCGGCGGCAGCGGGCTGGGTCTGGCCATCGTGGCCGAGATCGCACAGTCGCACGGCGCGCGCGTCTTTCTGGA
AGATGCGGCGCCGGGGCTGTGTGTGCGGGTGGTGTTTCCTGTGACCGCCTGA

Upstream 100 bases:

>100_bases
CGGCGCTGATTCGCAATATCCGCGGGGTGGGCTATGTGATCCCCGCCGAAAGCGGCGCGGAACAAGACACCAAGGGTGGT
CCCGAGGGAGCCATGCATTG

Downstream 100 bases:

>100_bases
TCTGTCGGCTGATCAGAGTACCGGCGCCACCAGCGGCTCGCCGGCAAAGTGCCGCCGCGCGTTCTCGACGAACTGGCTGA
CCGAGGCGAAGATTGCTTCG

Product: sensory histidine kinase in two-component regulatory system

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MRSIQRTLLWWLAAGLAVGIAVATALIYGQARQEANALFDYQMKQLAAALPSQFSAPAPPPFDSGSATGADLLHADEDVV
IHIWDGSGRSLYLSHSHPALPPQAELGFSNAQTNSGEWRIYSVQLGPAVVQIAQPMSARRTLAAHMALRTVAPLLLLLPL
LGWLVWLAVGRGLRPLREIASEVSARDANTLAPLSVRNMPVEIAPLSDALNQLLGRLAHAIDTQRAFVADAAHALRTPLA
ALQLQAQLVERAENAEARQEAVGQLRQGLERLTHLVAQLLTLARQEPGAVPPPHEPIDLRELAVGVVADMSQAAINRDID
LGLDDKAGSQATVRGDADALRILLTNLVDNALQYIPRGGCIDVRVSEIAAGVELAVIDNGPGISAAERERVFDRFYRVPD
APTGGSGLGLAIVAEIAQSHGARVFLEDAAPGLCVRVVFPVTA

Sequences:

>Translated_443_residues
MRSIQRTLLWWLAAGLAVGIAVATALIYGQARQEANALFDYQMKQLAAALPSQFSAPAPPPFDSGSATGADLLHADEDVV
IHIWDGSGRSLYLSHSHPALPPQAELGFSNAQTNSGEWRIYSVQLGPAVVQIAQPMSARRTLAAHMALRTVAPLLLLLPL
LGWLVWLAVGRGLRPLREIASEVSARDANTLAPLSVRNMPVEIAPLSDALNQLLGRLAHAIDTQRAFVADAAHALRTPLA
ALQLQAQLVERAENAEARQEAVGQLRQGLERLTHLVAQLLTLARQEPGAVPPPHEPIDLRELAVGVVADMSQAAINRDID
LGLDDKAGSQATVRGDADALRILLTNLVDNALQYIPRGGCIDVRVSEIAAGVELAVIDNGPGISAAERERVFDRFYRVPD
APTGGSGLGLAIVAEIAQSHGARVFLEDAAPGLCVRVVFPVTA
>Mature_443_residues
MRSIQRTLLWWLAAGLAVGIAVATALIYGQARQEANALFDYQMKQLAAALPSQFSAPAPPPFDSGSATGADLLHADEDVV
IHIWDGSGRSLYLSHSHPALPPQAELGFSNAQTNSGEWRIYSVQLGPAVVQIAQPMSARRTLAAHMALRTVAPLLLLLPL
LGWLVWLAVGRGLRPLREIASEVSARDANTLAPLSVRNMPVEIAPLSDALNQLLGRLAHAIDTQRAFVADAAHALRTPLA
ALQLQAQLVERAENAEARQEAVGQLRQGLERLTHLVAQLLTLARQEPGAVPPPHEPIDLRELAVGVVADMSQAAINRDID
LGLDDKAGSQATVRGDADALRILLTNLVDNALQYIPRGGCIDVRVSEIAAGVELAVIDNGPGISAAERERVFDRFYRVPD
APTGGSGLGLAIVAEIAQSHGARVFLEDAAPGLCVRVVFPVTA

Specific function: Member of a two-component regulatory system qseB/qseC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=447, Percent_Identity=29.7539149888143, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI1790551, Length=278, Percent_Identity=34.1726618705036, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1786783, Length=452, Percent_Identity=26.3274336283186, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1786600, Length=263, Percent_Identity=33.4600760456274, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788393, Length=229, Percent_Identity=32.7510917030568, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1788279, Length=390, Percent_Identity=24.8717948717949, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1790346, Length=286, Percent_Identity=29.3706293706294, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1787374, Length=298, Percent_Identity=27.1812080536913, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790436, Length=201, Percent_Identity=33.3333333333333, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1786912, Length=221, Percent_Identity=29.4117647058824, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789149, Length=244, Percent_Identity=25.4098360655738, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790861, Length=251, Percent_Identity=29.4820717131474, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1787894, Length=235, Percent_Identity=30.2127659574468, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788713, Length=249, Percent_Identity=24.0963855421687, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1789808, Length=242, Percent_Identity=26.4462809917355, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI145693157, Length=234, Percent_Identity=23.5042735042735, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082128, Length=250, Percent_Identity=26.8, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788549, Length=198, Percent_Identity=23.2323232323232, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 47149; Mature: 47149

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSIQRTLLWWLAAGLAVGIAVATALIYGQARQEANALFDYQMKQLAAALPSQFSAPAPP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PFDSGSATGADLLHADEDVVIHIWDGSGRSLYLSHSHPALPPQAELGFSNAQTNSGEWRI
CCCCCCCCCCHHEECCCCEEEEEEECCCCEEEEECCCCCCCCCHHCCCCCCCCCCCCEEE
YSVQLGPAVVQIAQPMSARRTLAAHMALRTVAPLLLLLPLLGWLVWLAVGRGLRPLREIA
EEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
SEVSARDANTLAPLSVRNMPVEIAPLSDALNQLLGRLAHAIDTQRAFVADAAHALRTPLA
HHHHHCCCCCCCCCEECCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALQLQAQLVERAENAEARQEAVGQLRQGLERLTHLVAQLLTLARQEPGAVPPPHEPIDLR
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
ELAVGVVADMSQAAINRDIDLGLDDKAGSQATVRGDADALRILLTNLVDNALQYIPRGGC
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCE
IDVRVSEIAAGVELAVIDNGPGISAAERERVFDRFYRVPDAPTGGSGLGLAIVAEIAQSH
EEEEHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHC
GARVFLEDAAPGLCVRVVFPVTA
CCEEEEECCCCCEEEEEEEECCC
>Mature Secondary Structure
MRSIQRTLLWWLAAGLAVGIAVATALIYGQARQEANALFDYQMKQLAAALPSQFSAPAPP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PFDSGSATGADLLHADEDVVIHIWDGSGRSLYLSHSHPALPPQAELGFSNAQTNSGEWRI
CCCCCCCCCCHHEECCCCEEEEEEECCCCEEEEECCCCCCCCCHHCCCCCCCCCCCCEEE
YSVQLGPAVVQIAQPMSARRTLAAHMALRTVAPLLLLLPLLGWLVWLAVGRGLRPLREIA
EEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
SEVSARDANTLAPLSVRNMPVEIAPLSDALNQLLGRLAHAIDTQRAFVADAAHALRTPLA
HHHHHCCCCCCCCCEECCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALQLQAQLVERAENAEARQEAVGQLRQGLERLTHLVAQLLTLARQEPGAVPPPHEPIDLR
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
ELAVGVVADMSQAAINRDIDLGLDDKAGSQATVRGDADALRILLTNLVDNALQYIPRGGC
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCE
IDVRVSEIAAGVELAVIDNGPGISAAERERVFDRFYRVPDAPTGGSGLGLAIVAEIAQSH
EEEEHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHC
GARVFLEDAAPGLCVRVVFPVTA
CCEEEEECCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]