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The map label for this gene is yfdE [H]

Identifier: 94314444

GI number: 94314444

Start: 2271579

End: 2272715

Strand: Direct

Name: yfdE [H]

Synonym: Rmet_5525

Alternate gene names: 94314444

Gene position: 2271579-2272715 (Clockwise)

Preceding gene: 94314432

Following gene: 94314450

Centisome position: 88.04

GC content: 58.75

Gene sequence:

>1137_bases
ATGGGGCCGTTGAAAGGCATCAAGGTCGTAGAAATGGCGGGAATTGCTCCAGGGCCATTCGCCGCGATGATGTTGGCCGA
CATGGGTGCGGAGGTGCTGTGCATTGAACGTCCTACTGCGGCACAGCATTGCCAACCGACTGCGTCGAACGTACTGCACC
GTAATCGTCGCTCACTGGCGTTGGACCTGAAAAATCCTGTTGCACTGAGAGTGTTGCGAAGACTGATTTCGTCTGCGAAT
GCCCTGATCGAGGGCTACCGTCCGGGAGTGATGGAGCGACTCGGATTGGGACCGGAGATCTGCCTCGCCGACAATCCGAG
CCTGGTGTACGGGCGCATGACTGGATGGGGTCAAGATGGGCCTATGGCACAAGCCGCAGGCCATGACGTGAATTACATTT
CGCTTACTGGGGCGCTTCACGCTATCGGACGTCGTGACGCTCCTCCTCCGATTCCGTTGAACCTCGTCGGGGATTTCGGC
GGTGGTGGGATGTTTCTGGCGTTCGGCGTTGTCTGCGCACTCCTAGAGGCTCAGACTTCCGGGCTGGGCCAAGTTGTCGA
CGCAGCGATGGTCGATGGCGCCGCGGCCATGATGGCCTACATGTGCGCTGCCCGAGCGTCGGGACGCTGGAGTGACCAAA
GAGGTGAGAATGTCCTTGACGGAGCAGCCCCTTGGTACCGGGTGTATGAGACTTCCGACGGACAATACATTTCTGTTGCC
GCGGCCGAGCCGAAATTTTACGCGGAACTCCTTCGCCTGTTAGAACTCTCCGATGAGACTTTGCCCGACCAATTCGATCG
CAGCGGCTGGCCAACCCTGACGGAACGCCTTACAACCGTATTCGGCACAAGAAGCCGCGCGGAATGGTCCAAGTTGCTGG
AAGGTACAGACGCTTGCTTTGCACCTGTGCTGTCTCTCGCTGAAGCACCAGGCCACCCCCACTTGCGAGCTCGAAACACA
TTCATTGAAGTCGACGGCATCATCCAGCCTGCCCCAGCTCCAAGATTTAGTCGGACCGTCCCGGCACAGCCACTGCCCTG
GACACCGGCGAAGACCGATGATCGCGCCACACTGACGGCTTGGGGCATTGACGAATACGAGATCTCACAACTGGAAAGCG
CTGGGATTCTCGGCTAA

Upstream 100 bases:

>100_bases
AATGGGAAATAGAACGGGCGCAACGAAAGCGTCTAGGGCGCACCTGTCGTGCGCGAGACGGGTCGATATGGACCACAGGC
TCAACTAAAGGGGGAATCAC

Downstream 100 bases:

>100_bases
GCGTCATAAGGGACGAGGCGCACGGCAGGCAACTGCTGTACGCCTCCTTGGGGAACTCAGTCACTCACCTGCTTCGCCCA
TCGCGGACTGTTAATGCTCA

Product: alpha-methylacyl-CoA racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MGPLKGIKVVEMAGIAPGPFAAMMLADMGAEVLCIERPTAAQHCQPTASNVLHRNRRSLALDLKNPVALRVLRRLISSAN
ALIEGYRPGVMERLGLGPEICLADNPSLVYGRMTGWGQDGPMAQAAGHDVNYISLTGALHAIGRRDAPPPIPLNLVGDFG
GGGMFLAFGVVCALLEAQTSGLGQVVDAAMVDGAAAMMAYMCAARASGRWSDQRGENVLDGAAPWYRVYETSDGQYISVA
AAEPKFYAELLRLLELSDETLPDQFDRSGWPTLTERLTTVFGTRSRAEWSKLLEGTDACFAPVLSLAEAPGHPHLRARNT
FIEVDGIIQPAPAPRFSRTVPAQPLPWTPAKTDDRATLTAWGIDEYEISQLESAGILG

Sequences:

>Translated_378_residues
MGPLKGIKVVEMAGIAPGPFAAMMLADMGAEVLCIERPTAAQHCQPTASNVLHRNRRSLALDLKNPVALRVLRRLISSAN
ALIEGYRPGVMERLGLGPEICLADNPSLVYGRMTGWGQDGPMAQAAGHDVNYISLTGALHAIGRRDAPPPIPLNLVGDFG
GGGMFLAFGVVCALLEAQTSGLGQVVDAAMVDGAAAMMAYMCAARASGRWSDQRGENVLDGAAPWYRVYETSDGQYISVA
AAEPKFYAELLRLLELSDETLPDQFDRSGWPTLTERLTTVFGTRSRAEWSKLLEGTDACFAPVLSLAEAPGHPHLRARNT
FIEVDGIIQPAPAPRFSRTVPAQPLPWTPAKTDDRATLTAWGIDEYEISQLESAGILG
>Mature_377_residues
GPLKGIKVVEMAGIAPGPFAAMMLADMGAEVLCIERPTAAQHCQPTASNVLHRNRRSLALDLKNPVALRVLRRLISSANA
LIEGYRPGVMERLGLGPEICLADNPSLVYGRMTGWGQDGPMAQAAGHDVNYISLTGALHAIGRRDAPPPIPLNLVGDFGG
GGMFLAFGVVCALLEAQTSGLGQVVDAAMVDGAAAMMAYMCAARASGRWSDQRGENVLDGAAPWYRVYETSDGQYISVAA
AEPKFYAELLRLLELSDETLPDQFDRSGWPTLTERLTTVFGTRSRAEWSKLLEGTDACFAPVLSLAEAPGHPHLRARNTF
IEVDGIIQPAPAPRFSRTVPAQPLPWTPAKTDDRATLTAWGIDEYEISQLESAGILG

Specific function: Unknown

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI42794625, Length=379, Percent_Identity=42.2163588390501, Blast_Score=314, Evalue=1e-85,
Organism=Homo sapiens, GI266456254, Length=379, Percent_Identity=42.2163588390501, Blast_Score=313, Evalue=1e-85,
Organism=Homo sapiens, GI266458393, Length=281, Percent_Identity=43.7722419928826, Blast_Score=243, Evalue=2e-64,
Organism=Homo sapiens, GI266458397, Length=249, Percent_Identity=46.5863453815261, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI300863128, Length=408, Percent_Identity=26.9607843137255, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI300863124, Length=434, Percent_Identity=25.8064516129032, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI42822893, Length=139, Percent_Identity=48.9208633093525, Blast_Score=138, Evalue=7e-33,
Organism=Homo sapiens, GI266458395, Length=139, Percent_Identity=48.9208633093525, Blast_Score=138, Evalue=9e-33,
Organism=Homo sapiens, GI300863126, Length=407, Percent_Identity=25.0614250614251, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI13376042, Length=432, Percent_Identity=23.6111111111111, Blast_Score=111, Evalue=1e-24,
Organism=Escherichia coli, GI87082093, Length=350, Percent_Identity=28.8571428571429, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1788717, Length=200, Percent_Identity=31, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1786222, Length=402, Percent_Identity=25.8706467661692, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI32564160, Length=335, Percent_Identity=34.3283582089552, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI115535051, Length=346, Percent_Identity=33.5260115606936, Blast_Score=209, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24585488, Length=338, Percent_Identity=43.7869822485207, Blast_Score=287, Evalue=9e-78,
Organism=Drosophila melanogaster, GI24648431, Length=378, Percent_Identity=27.5132275132275, Blast_Score=132, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: NA

Molecular weight: Translated: 40479; Mature: 40348

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPLKGIKVVEMAGIAPGPFAAMMLADMGAEVLCIERPTAAQHCQPTASNVLHRNRRSLA
CCCCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCHHHCCCHHHHHHHHCCCCEE
LDLKNPVALRVLRRLISSANALIEGYRPGVMERLGLGPEICLADNPSLVYGRMTGWGQDG
EECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEECCCCEEEEECCCCCCCC
PMAQAAGHDVNYISLTGALHAIGRRDAPPPIPLNLVGDFGGGGMFLAFGVVCALLEAQTS
CCHHHCCCCCEEEEHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHC
GLGQVVDAAMVDGAAAMMAYMCAARASGRWSDQRGENVLDGAAPWYRVYETSDGQYISVA
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEE
AAEPKFYAELLRLLELSDETLPDQFDRSGWPTLTERLTTVFGTRSRAEWSKLLEGTDACF
ECCCHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCHHHH
APVLSLAEAPGHPHLRARNTFIEVDGIIQPAPAPRFSRTVPAQPLPWTPAKTDDRATLTA
HHHHHHHHCCCCCCEEECCCEEEECCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
WGIDEYEISQLESAGILG
ECCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
GPLKGIKVVEMAGIAPGPFAAMMLADMGAEVLCIERPTAAQHCQPTASNVLHRNRRSLA
CCCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCHHHCCCHHHHHHHHCCCCEE
LDLKNPVALRVLRRLISSANALIEGYRPGVMERLGLGPEICLADNPSLVYGRMTGWGQDG
EECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEECCCCEEEEECCCCCCCC
PMAQAAGHDVNYISLTGALHAIGRRDAPPPIPLNLVGDFGGGGMFLAFGVVCALLEAQTS
CCHHHCCCCCEEEEHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHC
GLGQVVDAAMVDGAAAMMAYMCAARASGRWSDQRGENVLDGAAPWYRVYETSDGQYISVA
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEE
AAEPKFYAELLRLLELSDETLPDQFDRSGWPTLTERLTTVFGTRSRAEWSKLLEGTDACF
ECCCHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCHHHH
APVLSLAEAPGHPHLRARNTFIEVDGIIQPAPAPRFSRTVPAQPLPWTPAKTDDRATLTA
HHHHHHHHCCCCCCEEECCCEEEECCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
WGIDEYEISQLESAGILG
ECCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8125343 [H]