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The map label for this gene is etfA [H]

Identifier: 94314437

GI number: 94314437

Start: 2265044

End: 2265976

Strand: Reverse

Name: etfA [H]

Synonym: Rmet_5518

Alternate gene names: 94314437

Gene position: 2265976-2265044 (Counterclockwise)

Preceding gene: 94314438

Following gene: 94314436

Centisome position: 87.83

GC content: 64.63

Gene sequence:

>933_bases
ATGACTGCACTCGTCATTGCTGAACACGACAATCAATCGATCAAGGCCGCCACGCTGAACGCCGTGACGGCTGCTGCCCA
ATGCGGCGGCGATGTCCACGTGCTGGTGGCCGGCTCGAACGCCAAGGCTGCCGCCGATGCCGCCGCGAAGATCGCCGGCG
TGTCGAAGGTCCTGCTGGCCGACGCACCGTACTTTGGTGACGGCCTGGCCGAGAACGTTGCCGAGCAGATCCTGGCCGTC
GCCAGCGACTACTCGCACATCCTGGCTCCGGCAACCGCCTCGGGCAAGAACATCCTGCCGCGCGTGGCCGCCAAGCTGGA
CGTGGCCCAACTGTCGGACATCACCAAGGTCGATTCGCCCGACACGTTCGAGCGCCCGATCTACGCTGGCAACGCCATCG
CCATCGTGAAGTCGTCGGACAAGATCAAGGTCATCACCGTGCGCGGTACCGGTTTCGACGCCGCCGCCGCTGAAGGTGGC
TCGGCTTCCGTGGACACGATCCCGGCCGTGACCGACGCTGGCATCTCGCAATTCGTGTCGCGTGAAGTGACCAAGAGCGA
CCGTCCGGAACTGACCGCCGCCAAGATCATCGTTTCGGGTGGCCGTGGCGTGGGCTCGGGCGAGAACTACACCAAGGTAC
TGACCCCGCTGGCCGACAAGCTCGGCGCCGCGCTGGGCGCATCGCGTGCGGCAGTCGATGCCGGCTTCGTGCCGAACGAC
TACCAGGTCGGTCAGACTGGCAAGATCGTTGCCCCGCAGTTGTACATCGCCGTCGGTATCTCGGGTGCGATCCAGCATCT
GGCCGGCATGAAGGACTCCAAGGTGATCGTCGCGATCAACAAGGACGCTGAAGCCCCGATCTTCTCGGTGGCGGACTACG
GCCTGGTGGGCGACCTGAACACGATGGTGCCGGAGTTGGTGGGATCACTGTAA

Upstream 100 bases:

>100_bases
CGCGAAGCGCAGTGCTGGCGTGATGGTCCCGGATGTGGCCACGCTGGTGCAGAAGCTGAAGACGGAAGCCAAGGTTATCT
GAGCGCGGGGGAGATAGAAC

Downstream 100 bases:

>100_bases
CGTGTCCTGTTGACGACTCCTGTGCGTTGACGCAGGGACCAACCTGTAATAATTTCGGGTGGTGACTTCAACCAGCTTTA
TCCTGCTGGCTTACGGCGGC

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MTALVIAEHDNQSIKAATLNAVTAAAQCGGDVHVLVAGSNAKAAADAAAKIAGVSKVLLADAPYFGDGLAENVAEQILAV
ASDYSHILAPATASGKNILPRVAAKLDVAQLSDITKVDSPDTFERPIYAGNAIAIVKSSDKIKVITVRGTGFDAAAAEGG
SASVDTIPAVTDAGISQFVSREVTKSDRPELTAAKIIVSGGRGVGSGENYTKVLTPLADKLGAALGASRAAVDAGFVPND
YQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDAEAPIFSVADYGLVGDLNTMVPELVGSL

Sequences:

>Translated_310_residues
MTALVIAEHDNQSIKAATLNAVTAAAQCGGDVHVLVAGSNAKAAADAAAKIAGVSKVLLADAPYFGDGLAENVAEQILAV
ASDYSHILAPATASGKNILPRVAAKLDVAQLSDITKVDSPDTFERPIYAGNAIAIVKSSDKIKVITVRGTGFDAAAAEGG
SASVDTIPAVTDAGISQFVSREVTKSDRPELTAAKIIVSGGRGVGSGENYTKVLTPLADKLGAALGASRAAVDAGFVPND
YQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDAEAPIFSVADYGLVGDLNTMVPELVGSL
>Mature_309_residues
TALVIAEHDNQSIKAATLNAVTAAAQCGGDVHVLVAGSNAKAAADAAAKIAGVSKVLLADAPYFGDGLAENVAEQILAVA
SDYSHILAPATASGKNILPRVAAKLDVAQLSDITKVDSPDTFERPIYAGNAIAIVKSSDKIKVITVRGTGFDAAAAEGGS
ASVDTIPAVTDAGISQFVSREVTKSDRPELTAAKIIVSGGRGVGSGENYTKVLTPLADKLGAALGASRAAVDAGFVPNDY
QVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDAEAPIFSVADYGLVGDLNTMVPELVGSL

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=307, Percent_Identity=61.2377850162867, Blast_Score=361, Evalue=1e-100,
Organism=Homo sapiens, GI189181759, Length=271, Percent_Identity=62.3616236162362, Blast_Score=324, Evalue=8e-89,
Organism=Escherichia coli, GI1787990, Length=247, Percent_Identity=34.412955465587, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1786226, Length=229, Percent_Identity=34.061135371179, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI87082157, Length=252, Percent_Identity=32.5396825396825, Blast_Score=99, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17506929, Length=314, Percent_Identity=56.3694267515924, Blast_Score=330, Evalue=6e-91,
Organism=Saccharomyces cerevisiae, GI6325261, Length=285, Percent_Identity=45.6140350877193, Blast_Score=238, Evalue=7e-64,
Organism=Drosophila melanogaster, GI17136898, Length=312, Percent_Identity=62.1794871794872, Blast_Score=361, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24652801, Length=312, Percent_Identity=62.1794871794872, Blast_Score=361, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31304; Mature: 31173

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALVIAEHDNQSIKAATLNAVTAAAQCGGDVHVLVAGSNAKAAADAAAKIAGVSKVLLA
CEEEEEEECCCCCEEEEHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHEEEEE
DAPYFGDGLAENVAEQILAVASDYSHILAPATASGKNILPRVAAKLDVAQLSDITKVDSP
CCCCCCCHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
DTFERPIYAGNAIAIVKSSDKIKVITVRGTGFDAAAAEGGSASVDTIPAVTDAGISQFVS
CCCCCCEECCCEEEEEECCCCEEEEEEECCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHH
REVTKSDRPELTAAKIIVSGGRGVGSGENYTKVLTPLADKLGAALGASRAAVDAGFVPND
HHHCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCC
YQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDAEAPIFSVADYGLVGDLN
CEECCCCCEECCEEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCCCCCHH
TMVPELVGSL
HHHHHHHCCC
>Mature Secondary Structure 
TALVIAEHDNQSIKAATLNAVTAAAQCGGDVHVLVAGSNAKAAADAAAKIAGVSKVLLA
EEEEEEECCCCCEEEEHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHEEEEE
DAPYFGDGLAENVAEQILAVASDYSHILAPATASGKNILPRVAAKLDVAQLSDITKVDSP
CCCCCCCHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
DTFERPIYAGNAIAIVKSSDKIKVITVRGTGFDAAAAEGGSASVDTIPAVTDAGISQFVS
CCCCCCEECCCEEEEEECCCCEEEEEEECCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHH
REVTKSDRPELTAAKIIVSGGRGVGSGENYTKVLTPLADKLGAALGASRAAVDAGFVPND
HHHCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCC
YQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDAEAPIFSVADYGLVGDLN
CEECCCCCEECCEEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCCCCCHH
TMVPELVGSL
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]